Berro Mariano, Nelson Hamerschlak, Milovic Vera, Castro Belén, García P Andrés, Ferini Gonzalo, Real J José, Vitriu Adriana, Gimenez C Alberto, Bendek Georgina, Yantorno Sebastián, Martinez R Juliana, Saslavsky Martin, Jarchum Sol, Cerutti Amalia, Correa da S Cinthya, Rodrigues Morgani, Riera Leandro, Arbelbide Jorge, Kusminsky Gustavo, Basquiera A Lisa
BACKGROUND AND OBJECTIVES: Allogeneic stem cell transplantation (Allo-SCT) in elderly patients is a growing practice. We aimed to determine the graft-versus-host disease (GVHD) relapse-free survival (GRFS) in patients ≥65 years who underwent Allo-SCT in two countries from Latin America. PATIENTS AND METHODS: We performed a retrospective analysis of patients ≥65 years who underwent Allo-SCT in Argentina and Brazil from 2007 to 2019. RESULTS: Ninety-eight patients were evaluated, with primary diagnoses of acute myeloid leukemia and myelodysplastic syndrome; 30% of patients had a hematopoietic cell transplant-comorbidity index (HCT-CI) score ≥3 and 49% were in complete remission...
May 23, 2023: Hematology/oncology and Stem Cell Therapy