Journals Archives of Cardiovascular Dis...

Archives of Cardiovascular Diseases
Kenza Hamzi, Emmanuel Gall, François Roubille, Antonin Trimaille, Meyer Elbaz, Amine El Ouahidi, Nathalie Noirclerc, Damien Fard, Benoit Lattuca, Charles Fauvel, Marc Goralski, Sean Alvain, Aures Chaib, Nicolas Piliero, Guillaume Schurtz, Thibaut Pommier, Claire Bouleti, Christophe Tron, Guillaume Bonnet, Pascal Nhan, Simon Auvray, Antoine Léquipar, Jean-Guillaume Dillinger, Eric Vicaut, Patrick Henry, Solenn Toupin, Théo Pezel
BACKGROUND: Intensive cardiac care units (ICCUs) were created to manage ventricular arrhythmias after acute coronary syndromes, but have diversified to include a more heterogeneous population, the characteristics of which are not well depicted by conventional methods. AIMS: To identify ICCU patient subgroups by phenotypic unsupervised clustering integrating clinical, biological, and echocardiographic data to reveal pathophysiological differences. METHODS: During 7-22 April 2021, we recruited all consecutive patients admitted to ICCUs in 39 centers...
May 23, 2024: Archives of Cardiovascular Diseases
Alexandre Gautier, Nicolas Danchin, Gregory Ducrocq, Alexandra Rousseau, Yves Cottin, Guillaume Cayla, Fabrice Prunier, Isabelle Durand-Zaleski, Philippe Ravaud, Denis Angoulvant, Pierre Coste, Gilles Lemesle, Claire Bouleti, Batric Popovic, Emile Ferrari, Johanne Silvain, Olivier Dubreuil, Thibault Lhermusier, Pascal Goube, François Schiele, Gérald Vanzetto, Victor Aboyans, Romain Gallet, Hélène Eltchaninoff, Christophe Thuaire, Jean-Guillaume Dillinger, Franck Paganelli, Julie Gourmelen, Philippe Gabriel Steg, Tabassome Simon
BACKGROUND: Despite major advances in prevention and treatment, cardiovascular diseases - particularly acute myocardial infarction - remain a leading cause of death worldwide and in France. Collecting contemporary data about the characteristics, management and outcomes of patients with acute myocardial infarction in France is important. AIMS: The main objectives are to describe baseline characteristics, contemporary management, in-hospital and long-term outcomes of patients with acute myocardial infarction hospitalized in tertiary care centres in France; secondary objectives are to investigate determinants of prognosis (including periodontal disease and sleep-disordered breathing), to identify gaps between evidence-based recommendations and management and to assess medical care costs for the index hospitalization and during the follow-up period...
May 22, 2024: Archives of Cardiovascular Diseases
Pierre-Alexandre Fontanges, Christelle Marquie, Ali Houeijeh, Jean-Benoît Baudelet, Adélaïde Richard, Christian Amenyah, Sophie Lucidarme, Mathilde Bonnet, Alexandre Delarue, Saïd Bichali, Nala Abou Assi, Sylvestre Marechaux, Aymeric Menet, Guy Vaksmann, François Godart, Olivia Domanski
BACKGROUND: Hypertrophic cardiomyopathy (HCM) is rare in children, and sudden cardiac death (SCD) is difficult to predict. Two prognostic scores - HCM Risk-Kids and Precision Medicine for Cardiomyopathy (PRIMaCY) - were developed to assess the risk of SCD in the next 5 years in children with HCM. AIMS: To test the ability of these scores to predict SCD in children with HCM. Also, to identify factors associated with a severe cardiac rhythmic event (SCRE) (ventricular fibrillation, sustained ventricular tachycardia, heart transplant for rhythmic reasons or SCD)...
May 18, 2024: Archives of Cardiovascular Diseases
Laura Sofia Cardelli, Mariarosaria Magaldi, Audrey Agullo, Gaetan Richard, Erika Nogue, Philippe Berdague, Michel Galiner, Frédéric Georger, François Picard, Elvira Prunet, Nicolas Molinari, Arnaud Bourdin, Dany Jaffuel, François Roubille
BACKGROUND: Sacubitril/valsartan has been demonstrated to significantly improve left ventricular performance and remodelling in patients with heart failure. However, its effects on the right ventricle in patients with chronic heart failure and sleep-disordered breathing (SDB) have not been studied. AIM: To investigate the impact of sacubitril/valsartan treatment on right ventricular function in patients with SDB. METHODS: This was a subanalysis of an observational prospective multicentre study involving 101 patients...
May 18, 2024: Archives of Cardiovascular Diseases
Yohann Bohbot, Théo Pezel
No abstract text is available yet for this article.
May 18, 2024: Archives of Cardiovascular Diseases
Claire Bouleti, Clement Servoz, Benjamin Alos, Ehmer Carsten, Alexis Jacquier, Julien Ternacle, Jean-François Deux, Victoria Tea, Elie Mousseaux, Rodrigue Garcia, Guillaume Bonnet, Olivier Huttin, Mariama Akodad, Theodora Bejan-Angoulvant, Benoit Lattuca, Alban Redheuil, Nicolas Glatt, Denis Angoulvant, Phalla Ou
BACKGROUND: Acute myocarditis usually presents as chest pain with rising troponin and normal coronary arteries. Despite frequent favourable evolution at the acute phase, it is associated with heart failure and ventricular rhythm disorders, and is considered the leading cause of sudden cardiac death in young, apparently healthy, adults. There are no specific recommendations for acute myocarditis diagnosis and management, only expert consensus, given the lack of large databases. AIM: The main objective is to describe the contemporary presentation of acute myocarditis, its management and in-hospital outcomes...
May 8, 2024: Archives of Cardiovascular Diseases
Alessandro Parodi, Tania Puscas, Patricia Réant, Erwan Donal, Dorra M'Barek Raboudi, Clarisse Billon, Anne Bacher, Mohamed El Hachmi, Karim Wahbi, Xavier Jeunemaître, Albert Hagège
BACKGROUND: The efficacy of current pharmacological therapies in hypertrophic cardiomyopathy is limited. A cardiac myosin inhibitor, mavacamten, has recently been approved as a first-in-class treatment for symptomatic hypertrophic obstructive cardiomyopathy. AIMS: To assess the profile and burden of cardiac myosin inhibitor candidates in the hypertrophic cardiomyopathy prospective Register of hypertrophic cardiomyopathy (REMY) held by the French Society of Cardiology...
May 7, 2024: Archives of Cardiovascular Diseases
Karim Wahbi, Guillaume Bassez, Josselin Duchateau, Emmanuelle Salort-Campana, Savine Vicart, Jean-François Desaphy, Fabien Labombarda, Jean-Marc Sellal, Jean-Claude Deharo
In France, mexiletine - a class I antiarrhythmic drug - can be prescribed for the symptomatic treatment of myotonia of the skeletal muscles in adult patients with myotonic dystrophy under a compassionate use programme. Mexiletine is used according to its summary of product characteristics, which describes its use for myotonia treatment in adult patients with non-dystrophic myotonia, a different neuromuscular condition without cardiac involvement. A cardiac assessment is required prior to initiation and throughout treatment due to potential proarrhythmic effects...
April 15, 2024: Archives of Cardiovascular Diseases
Orianne Weizman, Estelle Gandjbakhch, Isabelle Magnin-Poull, Julie Proukhnitzky, Céline Bordet, Aurélien Palmyre, Adrien Bloch, Véronique Fressart, Philippe Charron
BACKGROUND: With the development of advanced sequencing techniques, genetic testing has emerged as a valuable tool for the work-up of non-ischaemic sudden cardiac arrest (SCA). AIMS: To evaluate the effectiveness of genetic testing in patients with unexplained SCA, according to clinical phenotype. METHODS: All patients who underwent molecular genetic testing for non-ischaemic SCA with no left ventricular cardiomyopathy between 2012 and 2021 in two French university hospitals were included...
April 15, 2024: Archives of Cardiovascular Diseases
Mary Philip, Jérôme Hourdain, Noémie Resseguier, Frédérique Gouriet, Jean-Paul Casalta, Florent Arregle, Sandrine Hubert, Alberto Riberi, Jean-Philippe Mouret, Vartan Mardigyan, Jean-Claude Deharo, Gilbert Habib
BACKGROUND: Aortic valve infective endocarditis may be complicated by high-degree atrioventricular block in up to 10-20% of cases. AIM: To assess high-degree atrioventricular block occurrence, contributing factors, prognosis and evolution in patients referred for aortic infective endocarditis. METHODS: Two hundred and five patients referred for aortic valve infective endocarditis between January 2018 and March 2021 were included in this study...
April 12, 2024: Archives of Cardiovascular Diseases
Nadav Willner, Virginia Nguyen, Graeme Prosperi-Porta, Helene Eltchaninoff, Ian G Burwash, Morgane Michel, Eric Durand, Martine Gilard, Christel Dindorf, Julien Dreyfus, Bernard Iung, Alain Cribier, Alec Vahanian, Karine Chevreul, David Messika-Zeitoun
BACKGROUND: Transcatheter (TAVR) has supplanted surgical (SAVR) aortic valve replacement (AVR). AIM: To evaluate whether adoption of this technology has varied according to centre volume at the nationwide level. METHODS: From an administrative hospital-discharge database, we collected data on all AVRs performed in France between 2007 and 2019. Centres were divided into terciles based on the annual number of SAVRs performed in 2007-2009 ("before TAVR era")...
April 12, 2024: Archives of Cardiovascular Diseases
Quentin Fischer, Vincent Pham, Gabriel Seret, Pierre Brami, Fabien Picard, Olivier Varenne
Coronary artery disease in older patients is more frequently diffuse and complex, and is often treated by percutaneous coronary intervention on top of medical therapy. There are currently no specific recommendations for antiplatelet therapy in patients aged≥75 years. Aspirin remains pivotal, and is still indicated as a long-term treatment after percutaneous coronary intervention. In addition, a P2Y12 inhibitor is administered for 6-12 months according to clinical presentation. Age is a minor bleeding risk factor, but because older patients often have several co-morbidities, they are considered as having a high bleeding risk according to different scoring systems...
April 12, 2024: Archives of Cardiovascular Diseases
Alexandre Salaun, Emmanuel de Maistre, Marlène Daller, Chan Sombrun, Frédéric Chagué, Florence Bichat, Luc Rochette, Nicolas Danchin, Laurent Fauchier, Marianne Zeller, Yves Cottin
Around 10% of patients with acute coronary syndrome are treated by vitamin K antagonists or non-vitamin K antagonist oral anticoagulants for various indications. The initial management of these patients is highly complex, and new guidelines specify that, only during percutaneous coronary intervention, a bolus of unfractionated heparin is recommended in one of the following circumstances: (1) if the patient is receiving a non-vitamin K antagonist oral anticoagulant; or (2) if the international normalized ratio is<2...
April 12, 2024: Archives of Cardiovascular Diseases
Jean-Sébastien Hulot, Philip Janiak, Philippe Boutinaud, Pierre Boutouyrie, Frédérique Chézalviel-Guilbert, Jean-Joseph Christophe, Ariel Cohen, Thibaud Damy, Juliette Djadi-Prat, Hüseyin Firat, Pierre-Yves Hervé, Richard Isnard, Guillaume Jondeau, Elie Mousseaux, Mathieu Pernot, Pierre Prot, Benoit Tyl, Gilles Soulat, Damien Logeart
BACKGROUND: Heart failure with preserved ejection fraction (HFpEF) is a heterogeneous syndrome that is poorly defined, reflecting an incomplete understanding of its pathophysiology. AIM: To redefine the phenotypic spectrum of HFpEF. METHODS: The PACIFIC-PRESERVED study is a prospective multicentre cohort study designed to perform multidimensional deep phenotyping of patients diagnosed with HFpEF (left ventricular ejection fraction≥50%), patients with heart failure with reduced ejection fraction (left ventricular ejection fraction≤40%) and subjects without overt heart failure (3:2:1 ratio)...
April 12, 2024: Archives of Cardiovascular Diseases
Emmanuel Messas
No abstract text is available yet for this article.
May 2024: Archives of Cardiovascular Diseases
François Diévart, Eric Bruckert, Victor Aboyans, Saïd Bekka, Franck Boccara, Barthelemy Bourdon Baron Munoz, Joseph Emmerich, Michel Farnier, Antonio Gallo, Gilles Lemesle, François Paillard, François Schiele, Serge Kownator
Low-density lipoprotein cholesterol has been established as a powerful cardiovascular risk factor; its reduction provides a clinical benefit in primary cardiovascular prevention, irrespective of the characteristics of the patients treated. It is useful to tailor low-density lipoprotein cholesterol targets according to the magnitude of cardiovascular risk (low, high or very high) in order to reduce the cardiovascular risk as fully as possible. In order to provide a uniform approach, it is necessary to propose recommendations for good practice, defining strategies for reducing low-density lipoprotein cholesterol...
May 2024: Archives of Cardiovascular Diseases
Antoine Delinière, Francis Bessière, Leslie Placide, Jean-Luc Pasquié, Christelle Haddad, Solenn Tirel, Hajira Mokhtar, Elodie Morel, Kevin Gardey, Arnaud Dulac, Geoffroy Ditac, Frédéric Sacher, Isabelle Denjoy, Philippe Chevalier
BACKGROUND: In patients with congenital long QT syndrome (LQTS), the risk of ventricular arrhythmia is correlated with the duration of the corrected QT interval and the changes in the ST-T wave pattern on the 12-lead surface electrocardiogram (12L-ECG). Remote monitoring of these variables could be useful. AIM: To evaluate the abilities of two wearable electrocardiogram devices (Apple Watch and KardiaMobile 6L) to provide reliable electrocardiograms in terms of corrected QT interval and ST-T wave patterns in patients with LQTS...
May 2024: Archives of Cardiovascular Diseases
Marjorie Richardson, Jean Philippe Bonnet, Capucine Coulon, Olivia Domanski, Benjamin Constans, Max Gonzalez Estevez, Sophie Gautier, Luisa Marsili, Yasmine Ould Hamoud, Augustin Coisne, Hélène Ridon, Anne-Sophie Polge, Stéphanie Mouton, Yasmine Haddad, Francis Juthier, Mouhamed Moussa, Claire Mounier Vehier, Gilles Lemesle, Guillaume Schurtz, Charles Garabedian, Mercedes Jourdain, Sandro Ninni, François Brigadeau, David Montaigne, Nicolas Lamblin, Louise Ghesquiere
BACKGROUND: Cardiovascular diseases (CVDs) are currently the leading cause of maternal death in Western countries. Although multidisciplinary cardio-obstetric teams are recommended to improve the management of pregnant women with CVD, data supporting this approach are scarce. AIMS: To describe the characteristics and outcomes of pregnant patients with CVD managed within the cardio-obstetric programme of a tertiary centre. METHODS: We included every pregnant patient with history of CVD managed by our cardio-obstetric team between June 2017 and December 2019, and collected all major cardiovascular events (death, heart failure, acute coronary syndromes, stroke, endocarditis and aortic dissection) that occurred during pregnancy, peripartum and the following year...
May 2024: Archives of Cardiovascular Diseases
Miloud Cherbi, Eric Bonnefoy, Etienne Puymirat, Nicolas Lamblin, Edouard Gerbaud, Laurent Bonello, Bruno Levy, Pascal Lim, Laura Muller, Hamid Merdji, Grégoire Range, Emile Ferrari, Meyer Elbaz, Hadi Khachab, Jeremy Bourenne, Marie-France Seronde, Nans Florens, Guillaume Schurtz, Vincent Labbé, Brahim Harbaoui, Gerald Vanzetto, Nicolas Combaret, Benjamin Marchandot, Benoit Lattuca, Guillaume Leurent, Stanislas Faguer, François Roubille, Clément Delmas
BACKGROUND: Chronic kidney disease (CKD) is one of the leading causes of death worldwide, closely interrelated with cardiovascular diseases, ultimately leading to the failure of both organs - the so-called "cardiorenal syndrome". Despite this burden, data related to cardiogenic shock outcomes in CKD patients are scarce. METHODS: FRENSHOCK (NCT02703038) was a prospective registry involving 772 patients with cardiogenic shock from 49 centres. One-year outcomes (rehospitalization, death, heart transplantation, ventricular assist device) were analysed according to history of CKD at admission and were adjusted on independent predictive factors...
March 20, 2024: Archives of Cardiovascular Diseases
Mathilde Chanut, Vincent Bonny, Anne-Christine Joly, Hafid Ait-Oufella, Eric Maury, Stephane Ederhy, Jérémie Joffre
No abstract text is available yet for this article.
March 5, 2024: Archives of Cardiovascular Diseases
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