Mahamat Hissene Mahamat, Adeline Ségard, Jean-Baptiste Rayaisse, Rafael Argiles-Herrero, Andrew Gordon Parker, Philippe Solano, Adly Mohamed Mohamed Abd-Alla, Jérémy Bouyer, Sophie Ravel
BACKGROUND: Human African trypanosomiasis (HAT) is a neglected tropical disease caused by Trypanosoma brucei gambiense transmitted by tsetse flies in sub-Saharan West Africa. In southern Chad the most active and persistent focus is the Mandoul focus, with 98% of the reported human cases, and where African animal trypanosomosis (AAT) is also present. Recently, a control project to eliminate tsetse flies (Glossina fuscipes fuscipes) in this focus using the sterile insect technique (SIT) was initiated...
March 22, 2023: Parasites & Vectors
Antsa Rakotonirina, Pierre-Olivier Maquart, Claude Flamand, Chea Sokha, Sébastien Boyer
BACKGROUND: A total of 290 mosquito species are recorded in Cambodia among which 43 are known vectors of pathogens. As Cambodia is heavily affected by deforestation, a potential change in the dynamic of vector-borne diseases (VDBs) could occur through alteration of the diversity and density of sylvatic vector mosquitoes and induce an increase in their interactions with humans. Understanding mosquito diversity is therefore critical, providing valuable data for risk assessments concerning the (re)emergence of local VBDs...
March 21, 2023: Parasites & Vectors
Xuan Zhou, Lidan Wang, Pengchen Zhu, Zijiang Yang, Zhao Wang, Yijun Chen, Xiaobin Gu, Ran He, Jing Xu, Bo Jing, Guangyou Yang, Shun Chen, Shuangyang Wu, Yue Xie
BACKGROUND: Coccidiosis caused by Eimeria is one of the most severe chicken diseases and poses a great economic threat to the poultry industry. Understanding the evolutionary biology of chicken Eimeria parasites underpins development of new interactions toward the improved prevention and control of this poultry disease. METHODS: We presented an evolutionary blueprint of chicken coccidia by genetically characterizing complete mitogenome assemblies of 33 isolates representing all seven known Eimeria species infecting chickens in China...
March 19, 2023: Parasites & Vectors
Megan J Allman, Ya-Hsun Lin, D Albert Joubert, Jessica Addley-Cook, Maria Camila Mejía-Torres, Cameron P Simmons, Heather A Flores, Johanna E Fraser
BACKGROUND: Introgression of the bacterial endosymbiont Wolbachia into Aedes aegypti populations is a biocontrol approach being used to reduce arbovirus transmission. This requires mass release of Wolbachia-infected mosquitoes. While releases have been conducted using a variety of techniques, egg releases, using water-soluble capsules containing mosquito eggs and larval food, offer an attractive method due to its potential to reduce onsite resource requirements. However, optimisation of this approach is required to ensure there is no detrimental impact on mosquito fitness and to promote successful Wolbachia introgression...
March 18, 2023: Parasites & Vectors
Mengshi Yu, Yongfang Yao, Hongtao Xiao, Meng Xie, Ying Xiong, Shengzhi Yang, Qingyong Ni, Mingwang Zhang, Huailiang Xu
BACKGROUND: Blastocystis is a common intestinal protist with a wide range of hosts. Thus far, 38 subtypes have been identified. In recent years, wild animals have been confronted with habitat fragmentation as well as an increasing risk of zoonotic disease transmission due to human disturbance. Only limited data are available on Blastocystis infection and subtype distribution in wild rhesus macaques in China. The aim of the present study was to investigate the prevalence and genetic diversity of Blastocystis in nine wild rhesus macaque populations in China...
March 17, 2023: Parasites & Vectors
Emily L Pascoe, Ankje de Vries, Helen J Esser, Constantianus J M Koenraadt, Hein Sprong
BACKGROUND: Tick-borne encephalitis virus (TBEV) can cause severe neurological disease in humans. Its geographical distribution is expanding in Western Europe with unresolved causes and spatial patterns, necessitating enhanced surveillance. Monitoring the virus in the environment is complicated, as it usually relies on destructive sampling of small rodents to test organs for TBEV, which in addition to ethical considerations also raises issues for long-term monitoring or longitudinal studies...
March 16, 2023: Parasites & Vectors
Sándor Hornok, Andrei D Mihalca, Jenő Kontschán, Nóra Takács, Denis Fedorov, Olivier Plantard, Attila D Sándor
BACKGROUND: The subgenus Pholeoixodes contains Ixodes species typically associated with birds that nest in cavities or with carnivorous mammals that are burrow-dwelling. Among ticks infesting the latter, Ixodes rugicollis is regarded as the rarest species in the western Palearctic. Despite the unique morphology of this species, its identification (especially of subadult stages) is difficult, and molecular-phylogenetic data to offer other diagnostic methods and a better understanding of its taxonomy are not available...
March 16, 2023: Parasites & Vectors
María Del Pilar Pérez Rodríguez, Claudia Alarcón-Torrecillas, Miguel Pericacho, Iván Rodríguez-Escolar, Elena Carretón, Rodrigo Morchón
BACKGROUND: Angiogenesis is defined as the formation of new vessels by sprouting of endothelial cells from pre-existing vessels in response to stimuli, such as hypoxia or inflammation. Subcutaneous dirofilariasis, caused by Dirofilaria repens, is a zoonotic disease characterized by the formation of subcutaneous nodules with the presence of at least one encapsulated worm, showing perivascular vascularization around it. The aim of this study is to analyze whether the somatic antigen of adult D...
March 16, 2023: Parasites & Vectors
Olga Barranco-Gómez, Jessica Carreira De Paula, Jennifer Solano Parada, Tamara Gómez-Moracho, Ana Vic Marfil, María Zafra, Francisco José Orantes Bermejo, Antonio Osuna, Luis Miguel De Pablos
No abstract text is available yet for this article.
March 16, 2023: Parasites & Vectors
Faustus Akankperiwen Azerigyik, Astri Nur Faizah, Daisuke Kobayashi, Michael Amoa-Bosompem, Ryo Matsumura, Izumi Kai, Toshinori Sasaki, Yukiko Higa, Haruhiko Isawa, Shiroh Iwanaga, Tomoko Ishino
BACKGROUND: The Getah virus (GETV) is a mosquito-borne Alphavirus (family Togaviridae) that is of significant importance in veterinary medicine. It has been associated with major polyarthritis outbreaks in animals, but there are insufficient data on its clinical symptoms in humans. Serological evidence of GETV exposure and the risk of zoonotic transmission makes GETV a potentially medically relevant arbovirus. However, minimal emphasis has been placed on investigating GETV vector transmission, which limits current knowledge of the factors facilitating the spread and outbreaks of GETV...
March 15, 2023: Parasites & Vectors
Li He, Hong-Run Zhang, Wen-Da Di, Fang-Fang Li, Chun-Qun Wang, Xin Yang, Xiao-Fang Liu, Min Hu
BACKGROUND: The proteasome in eukaryotic cells can degrade a variety of proteins and plays an important role in regulating the cell cycle, cell survival and apoptosis. The proteasome receives much attention as a potential chemotherapeutic target for treatment of a variety of infectious parasitic diseases, but few studies of proteasomes have been done on parasitic nematodes. METHODS: A proteasomal β5 subunit encoding gene (named Hc-pbs-5) and its inferred product (Hc-PBS-5) in Haemonchus contortus were identified and characterized in this study...
March 15, 2023: Parasites & Vectors
Eleonora Perugini, Wamdaogo M Guelbeogo, Federica Guglielmo, Cristiana Poggi, Eugenio Gabrieli, Hilary Ranson, Alessandra Della Torre, Marco Pombi
BACKGROUND: Mosquito and human behaviour interaction is a key determinant of the maximum level of protection against malaria that can be provided by insecticide-treated nets (ITNs). Nevertheless, scant literature focuses on this interaction, overlooking a fundamental factor for efficient malaria control. This study aims to estimate malaria transmission risk in a Burkina Faso village by integrating vector biting rhythms with some key information about human habits. METHODS: Indoor/outdoor human landing catches were conducted for 16 h (16:00-08:00) during 8 nights (September 2020) in Goden village...
March 15, 2023: Parasites & Vectors
Lin-Min Wang, Ni Li, Mao Zhang, Qi Tang, Hong-Zheng Lu, Qing-Ya Zhou, Jia-Xuan Niu, Liang Xiao, Zhe-Yu Peng, Chao Zhang, Miao Liu, Duo-Quan Wang, Sheng-Qun Deng
BACKGROUND: Aedes aegypti is a vector that transmits various viral diseases, including dengue and Zika. The radiation-based sterile insect technique (SIT) has a limited effect on mosquito control because of the difficulty in irradiating males without reducing their mating competitiveness. In this study, the insect sex pheromone heptacosane was applied to Ae. aegypti males to investigate whether it could enhance the mating competitiveness of irradiated males. METHODS: Heptacosane was smeared on the abdomens of Ae...
March 15, 2023: Parasites & Vectors
Daniel A J Parsons, Anthony J Walker, Aidan M Emery, Joanne P Webster, Scott P Lawton
BACKGROUND: Despite successful control efforts in China over the past 60 years, zoonotic schistosomiasis caused by Schistosoma japonicum remains a threat with transmission ongoing and the risk of localised resurgences prompting calls for a novel integrated control strategy, with an anti-schistosome vaccine as a core element. Anti-schistosome vaccine development and immunisation attempts in non-human mammalian host species, intended to interrupt transmission, and utilising various antigen targets, have yielded mixed success, with some studies highlighting variation in schistosome antigen coding genes (ACGs) as possible confounders of vaccine efficacy...
March 14, 2023: Parasites & Vectors
Zhenxiao Lu, Hang Hu, Yashan Song, Siyi Zhou, Olalekan Opeyemi Ayanniyi, Qianming Xu, Zhenyu Yue, Congshan Yang
BACKGROUND: Apicomplexa consist of numerous pathogenic parasitic protistan genera that invade host cells and reside and replicate within the parasitophorous vacuole (PV). Through this interface, the parasite exchanges nutrients and affects transport and immune modulation. During the intracellular life-cycle, the specialized secretory organelles of the parasite secrete an array of proteins, among which dense granule proteins (GRAs) play a major role in the modification of the PV. Despite this important role of GRAs, a large number of potential GRAs remain unidentified in Apicomplexa...
March 14, 2023: Parasites & Vectors
Marcelly Nassar, Larissa A Martins, Josiane Betim de Assis, Eliane Esteves, Anderson Sá-Nunes, Marcelo B Labruna, Sirlei Daffre, Andrea C Fogaça
BACKGROUND: The tick Amblyomma sculptum is the major vector of Rickettsia rickettsii, the causative agent of the highly lethal Brazilian spotted fever. It has been shown that R. rickettsii inhibits apoptosis in both human endothelial cells and tick cells. Apoptosis is regulated by different factors, among which inhibitors of apoptosis proteins (IAPs) play a central role. In the study reported here, we selected an IAP of A. sculptum that has not yet been characterized to assess its role in cell death and to determine the effects of its gene silencing on tick fitness and R...
March 10, 2023: Parasites & Vectors
Thomas Geurden, Sara Chapin, John W McCall, Abdelmoneim Mansour, Sean P Mahabir, Kristina Kryda, Tom McTier
BACKGROUND: Aedes aegypti is one of the main species responsible for the transmission of mosquito-borne pathogens worldwide. The isoxazoline Sarolaner has excellent efficacy as an acaricide against ticks and mites and as an insecticide against fleas, and potential efficacy against other insects. METHODS: In each of two laboratory studies, 24 dogs were randomly allocated (n = 8/group) to an untreated control group, a Simparica-treated group (at the minimum dose of 2...
March 9, 2023: Parasites & Vectors
David M Poché, Donald Wagner, Kylie Green, Zachary Smith, Noah Hawthorne, Batchimeg Tseveenjav, Richard M Poché
BACKGROUND: Odocoileus virginianus (the white-tailed deer) is a key reproductive host for medically important tick species, including Ixodes scapularis and Amblyomma americanum. Orally administering a systemic acaricide to white-tailed deer has the potential to reduce tick reproduction, abundance and pathogen-infected tick bites. Prior studies have demonstrated considerable efficacy of a low-dose fipronil mouse bait in controlling larval I. scapularis parasitizing the pathogen reservoir, Peromyscus leucopus...
March 9, 2023: Parasites & Vectors
Ju Hyeon Kim, Do Eun Lee, Sang Youn Park, John M Clark, Si Hyeock Lee
BACKGROUND: Head louse females secrete liquid gel, which is mainly composed of the louse nit sheath protein 1 (LNSP1) and LNSP2, when they lay eggs. The gel is crosslinked by transglutaminase (TG) to form the nit sheath, which covers most of the egg except the top operculum area where breathing holes are located. Knowledge on the selective mechanism of nit sheath solidification to avoid uncontrolled crosslinking could lead to designing a novel method of louse control, but no information is available yet...
March 9, 2023: Parasites & Vectors
Panagiota Ligda, Manuela Gizzarelli, Despoina Kostopoulou, Valentina Foglia Manzillo, Anastasios Saratsis, Katerina Saratsi, Susan Michler, Hannah Ringeisen, Annette Boegel, Bettina Schunack, Matthias Pollmeier, Michalis Kontrafouris, Ourania Tsatsaki, Gaetano Oliva, Smaragda Sotiraki
BACKGROUND: The objective of this field study was to assess the effect of treating a considerable portion of a dog population naturally exposed to canine vector-borne pathogens (CVBPs) in endemic areas with a 10% w/w imidacloprid/4.5% w/w flumethrin collar (Seresto®) on the transmission of CVBPs and the resulting incidence of infection. METHODS: A total of 479 dogs from two sites were enrolled in the study. Collars were placed on all dogs continuously for 21 months, with replacement of the collar every 7 months...
March 7, 2023: Parasites & Vectors
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read

Save your favorite articles in one place with a free QxMD account.


Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.