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BMC Research Notes

Baymot Workineh, Fantahun Ayenew Mekonnen, Mekonnen Sisay, Kedir Abdela Gonete
OBJECTIVE: The aim of this study was to assess the occurrence of malaria outbreak and investigate contracting factors of malaria in Simada District, Northwest Ethiopia. A single observation original research. RESULTS: Among the total 54 cases, 44 (81.5%) of them were confirmed malaria cases. The average attack rate was 20 per 100 and slide positivity rate was 81.5%. People in the age group of 5-14 years were most affected with an attack rate of 37%. Presence of water bodies for mosquito breeding inside less than 1 km radius (AOR = 3...
May 17, 2019: BMC Research Notes
Madinna Mustafa, Fatima Fathy, Abubaker Mirghani, Mona A Mohamed, Mohamed S Muneer, Abdallah E Ahmed, Mohamed Siralkhatim Ali, Rihab A Omer, Emmanuel E Siddig, Nouh S Mohamed, Amjed M Abd Elkareem
OBJECTIVES: Toxoplasma gondii is an opportunistic parasite that causes a clinical manifestation known as toxoplasmosis. We investigated the prevalence and potential risk factors of T. gondii infection among women in Khartoum, Sudan. A sero-parasitological cross-sectional study included 100 women aging between 15 and 50 years old was conducted between January and November 2018. Serum samples were collected and investigated for the presence of anti-T. gondii immunoglobulins. RESULTS: Mean age of the women population included was 26...
May 16, 2019: BMC Research Notes
Ljiljana Milic, Aleksandar Karamarkovic, Dusan Popadic, Ana Sijacki, Ilijana Grigorov, Emina Milosevic, Vladica Cuk, Predrag Pesko
OBJECTIVE: Peptic ulcer disease is a condition in which an important role has infection with H. pylori. The most common complication of peptic ulcer is bleeding. The presence of H. pylori triggers local and systemic cytokine signaling which may affect processes such as healing, gastric or duodenal rupture, and carcinogenesis. In this study, we examined the concentrations of IL-1β, IL-6, IL-10, TNF, TGF-β and IL-17A in serum by enzyme immunoassay and their mRNA expressions in periulcer biopsies obtained from patients with bleeding peptic ulcer by means of real-time-PCR...
May 15, 2019: BMC Research Notes
Yuji Ogihara
OBJECTIVE: The current research examined age differences in self-esteem in Japan from young adults aged 20 to the elderly aged 69 with a focus on self-esteem trajectories from middle age to old age. Previous research in European American cultures has indicated that self-esteem rises from young adulthood into middle age, and sharply declines starting in one's 50s or 60s. However, it was unclear whether this sharp drop would be found in Japan. Therefore, the present research investigated whether the same age differences were present in Japan by analyzing data from a large and diverse sample...
May 15, 2019: BMC Research Notes
Ashenafi Habte Woyessa, Tahir Hasen Ahmed
OBJECTIVE: Despite the fact that quality antenatal care is one of the essential aspects in maternal and child health care, the current perceived quality and associated factors of this service is not well acknowledged in Ethiopia. This study was therefore undertaken to assess focused antenatal care service utilization and associated factors in western Ethiopia. RESULT: This study has measured the utilization of focused antenatal care services in terms of regularity of frequency of attendance, initiation time and completeness of the components...
May 15, 2019: BMC Research Notes
Ayele Semachew Kasa, Alebachew Minibel, Getasew Mulat Bantie
OBJECTIVE: The aim of the study was to assess knowledge, attitude and preventive practice towards tuberculosis. RESULT: More than half of the study participants stated that bacteria are responsible agents in causing tuberculosis and as the same time 12.2% study participants thought that tuberculosis is not preventable disease. Overall, 54% of study participants had good knowledge, 68% had good attitude but only 48% had good practice in preventing tuberculosis. Compared to many national and international studies, knowledge, attitude and preventive practice towards tuberculosis was not satisfactory...
May 15, 2019: BMC Research Notes
Katherin Patsch, Naim Matasci, Anjana Soundararajan, Patricia Diaz, David B Agus, Daniel Ruderman, Mitchell E Gross
OBJECTIVE: Cell-free DNA (cfDNA) is an attractive cancer biomarker, as it is thought to reflect a component of the underlying genetic makeup of the tumor and is readily accessible in serial fashion. Because chemotherapy regimens are expected to act rapidly on cancer and cfDNA is cleared from the blood within minutes, we hypothesized that cfDNA would reflect immediate effects of treatment. Here, we developed a method for monitoring long cfDNA fragments, and report dynamic changes in response to cytotoxic chemotherapy...
May 15, 2019: BMC Research Notes
Markus J Ernst, Bettina B Sommer, André Meichtry, Christoph M Bauer
OBJECTIVES: A reliable detection of bony landmarks of the spine is necessary in order to determine rigid bodies and to reduce the variability of marker placement in a movement laboratory setting. In a first study on the thoracic and lumbar spine, we demonstrated that placing markers on their relative positions between two major landmarks was superior to palpation of specific bony landmarks. The aims of this study were to examine the intra-rater reliability when palpating for spinous processes (SPs) of the second (C2) and seventh cervical vertebrae (C7), to determine the distances between C2 and C7 and the relative position of C7 along the length between C2 and the posterior superior iliac spine (PSIS) level...
May 14, 2019: BMC Research Notes
Sarah Sharpe, Bridget Kool, Robyn Whittaker, Arier C Lee, Papaarangi Reid, Ian Civil, Shanthi Ameratunga
OBJECTIVE: Mobile Health approaches show promise as a delivery mode for alcohol screening and brief intervention. The 'YourCall' trial evaluated the effect of a low-intensity mobile phone text message brief intervention compared with usual care on hazardous drinking and alcohol-related harms among injured adults. This paper extends our previously published primary outcome analysis which revealed a significant reduction in hazardous drinking associated with the intervention at 3 months, with the effect maintained across 12 months follow-up...
May 14, 2019: BMC Research Notes
Marina Arkkukangas, Staffan Hultgren
OBJECTIVE: The elderly population over 65 is increasing globally, and interventions promoting health and preventive work, especially fall prevention, will constitute a large part of physiotherapists' duties in the near future. To address the challenges of promoting effective and sustainable health behavior changes among older persons, physiotherapists need support when it comes to how to apply behavior change strategies, especially in fall prevention. Therefore, the aim of this study was to describe implementation of motivational interviewing in a fall prevention exercise program...
May 14, 2019: BMC Research Notes
Tesfay Berhe, Hailay Gebreyesus, Haftom Desta
OBJECTIVE: Preterm deliveries were responsible for 3.1 million neonatal deaths that occurred globally in 2010, of them 35% were directly related to preterm. This study was aimed to assess the determinants of preterm birth among women delivered of Central zone. A facility-based cross-sectional study was carried out from March to May 2018, in four randomly selected hospitals of Central zone. A total of 413 participants were interviewed using a pre-tested structured questionnaire. Data were entered into Epi-info Version 3...
May 14, 2019: BMC Research Notes
Asefa Adimasu Taddese, Adhanom Gebreegziabher Baraki, Kassahun Alemu Gelaye
OBJECTIVES: The aim of this study was to determine the spatial modeling, seasonal variation of malaria and making prediction map of malaria in northwest Ethiopia. RESULTS: The overall average cumulative annual malaria incidence during the study period was 30 per 100 populations at risk. The highest proportion (29.2%) was observed from June 2015 to October 2016. In temporal analysis of clusters, the epidemic was observed from 2015/7/1 to 2016/12/31 throughout the study period in all districts...
May 14, 2019: BMC Research Notes
Bhuvan P Pathak, Eliott Pruett, Huazhong Guan, Vibha Srivastava
OBJECTIVES: Removal of selection marker genes from transgenic plants is highly desirable for their regulatory approval and public acceptance. This study evaluated the use of two nucleases, the yeast homing endonuclease, I-SceI, and the designed zinc finger nuclease, CCR5-ZFN, in excising marker genes from plants using rice and Arabidopsis as the models. RESULTS: In an in vitro culture assay, both nucleases were effective in precisely excising the DNA fragments marked by the nuclease target sites...
May 14, 2019: BMC Research Notes
Rajarshi Ghosh, Paul Kline
OBJECTIVE: QC analysis of carbohydrates has been historically cumbersome due to lengthy and laborious derivatization techniques and the requirement of complimentary instrumentation. HILIC-CAD has emerged as an effective platform for direct monosaccharide composition analysis of complex carbohydrates without derivatization. Although, several neutral sugars have been separated and detected using HILIC-CAD, there has not been any report on acidic and amino sugar analysis using this method...
May 14, 2019: BMC Research Notes
Takashi Kuragaichi, Yuki Kataoka, Chisato Miyakoshi, Tadashi Miyamoto, Yukihito Sato
OBJECTIVE: The risk of atherosclerotic cardiovascular disease (ASCVD) is estimated using the American College of Cardiology (ACC)/American Heart Association (AHA) Pooled Cohort Equations (PCEs). However, the accuracy of this tool remains controversial, particularly among patients who are recommended statin therapy according to the ACC/AHA guidelines. We performed external validation of PCEs among patients eligible for statin therapy using data from the systolic blood pressure intervention trial (SPRINT)...
May 14, 2019: BMC Research Notes
Keneth Iceland Kasozi, Aisha Bukenya, Ejike Daniel Eze, Josephine Kasolo, Dickson Stuart Tayebwa, Fred Ssempijja, Joy Suubo, Andrew Tamale, Isaac Echoru, Ibrahim Ntulume, Sarah Kemuma Onkoba, Lisa Nkatha Micheni, Emmanuel Tiyo Ayikobua, Oscar Hilary Asiimwe, Muhamudu Kalange
OBJECTIVE: The purpose of the study was to generate information on the safety of probiotics, thus the study objectives were to evaluate the effects of Yoba® on basic physiochemical properties. The study assessed male w1118 Drosophila melanogaster which were provided food supplemented with Yoba® at 1%, 3%, 6%, and 12% on motor function, total protein, catalase activity, and hydrogen peroxide scavenging activity and lifespan. RESULTS: Yoba® at high concentration (≥ 6%) increased locomotor activity in Drosophila melanogaster, however, total protein, catalase, and hydrogen peroxide scavenging activity were significantly higher at 1% Yoba® compared to 3%, 6%, and 12% Yoba® ...
May 14, 2019: BMC Research Notes
Diane Korkor Arhin, Kwaku Oppong Asante, Nuworza Kugbey, Mabel Oti-Boadi
OBJECTIVE: One of the pervasive problems in schools that has adverse implication on the wellbeing of students, is bullying victimisation. However, within sub-Saharan Africa, only few studies have examined how psychological distress influences bullying victimisation. The purpose of this study was to explore the association between bullying victimization and psychological distress among school going adolescents in Ghana. RESULTS: One hundred and ninety-eight (198) male and female students completed a series of self-report questionnaires measuring psychological distress (anxiety, stress and depression) and bullying victimisation in a cross-sectional survey...
May 10, 2019: BMC Research Notes
Helle Glud Binderup, Jonna Skov Madsen, Claus Lohman Brasen, Kim Houlind, Rikke Fredslund Andersen
OBJECTIVE: Circulating microRNAs are promising diagnostics and prognostics biomarkers in a wide variety of diseases. However, there is a critical reproducibility challenge, which in part may be due to preanalytical factors. MicroRNA purification has been identified as the major contributor to the total intra assay variation, thus we found great interest in recent papers describing methods for direct quantification of circulating microRNAs without the purification step. With one exception, all the studies we identified where a direct quantification of circulating microRNAs had been performed were using SYBR Green chemistry...
May 10, 2019: BMC Research Notes
Daniel Getacher Feleke, Edosa Kebede Wage, Tigist Getachew, Alemu Gedefie
OBJECTIVE: Intestinal parasitic infections are among the major cause of diseases of public health problems in sub-Saharan Africa. In Ethiopia, epidemiological information on street dwellers is very limited. So, this study aimed to determine the prevalence and associated factors of intestinal parasite among street dwellers' in Dessie town, North-East, Ethiopia. RESULTS: A cross-sectional study was carried out on street dwellers in Dessie town from November 2017 to February, 2018...
May 10, 2019: BMC Research Notes
David Francis Fullon Chan, Milagros M Herrera-Arroyo
OBJECTIVE: Laser/photocoagulation criteria for retinopathy of prematurity (ROP) are generally universal, with > 90% anatomic success reported in varied settings. Outcomes in the Philippines, a developing/lower-middle income nation, were examined. RESULTS: This single-center retrospective chart review covered years 2014 and 2015. Of 214 infants screened, 64 had any ROP. Thirty-four were treated, and 20 had documented outcomes. Only 15 of 25 eyes (8 infants) with laser treatment-requiring ROP were successes (60%)...
May 10, 2019: BMC Research Notes
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