Julie Antomarchi, Damien Ambrosetti, Charlotte Cohen, Jérôme Delotte, Anne Chevallier, Babou Karimdjee-Soilihi, Mélanie Ngo-Mai, Annie Schmid-Alliana, Heidy Schmid-Antomarchi
The recent successes of new cancer immunotherapy approaches have led to investigate their relevance in the context of the Endometrial Carcinoma (EC). These therapies, that take the tumor-induced immunosuppressive microenvironment into account, target the tumor immune escape, in particular the inhibitory receptors involved in the regulation of the effector T cells' activity (immune checkpoints). The aim of this study was to identify, in ECs, differences in intergrades immune status that could contribute to the differences in tumor aggressiveness, and could also be used as theranostic tools...
May 27, 2019: Cancer Microenvironment: Official Journal of the International Cancer Microenvironment Society