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Journal of the Mechanical Behavior of Biomedical Materials

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https://read.qxmd.com/read/30769233/a-noninvasive-mri-based-approach-to-estimate-the-mechanical-properties-of-human-knee-ligaments
#1
Hamid Naghibi, Valentina Mazzoli, Kaj Gijsbertse, Gerjon Hannink, Andre Sprengers, Dennis Janssen, Ton Van den Boogaard, Nico Verdonschot
Characterization of the main tibiofemoral ligaments is an essential step in developing patient-specific computational models of the knee joint for personalized surgery pre-planning. Tensile tests are commonly performed in-vitro to characterize the mechanical stiffness and rupture force of the knee ligaments which makes the technique unsuitable for in-vivo application. The time required for the limited noninvasive approaches for properties estimation based on knee laxity remained the main obstacle in clinical implementation...
February 7, 2019: Journal of the Mechanical Behavior of Biomedical Materials
https://read.qxmd.com/read/30776679/a-fast-degrading-plla-composite-with-a-high-content-of-functionalized-octacalcium-phosphate-mineral-phase-induces-stem-cells-differentiation
#2
Diego Clemente de Souza, Henrique de Luca Vahia de Abreu, Pedro Vitoriano de Oliveira, Luciane Portas Capelo, Maria Rita Passos-Bueno, Luiz Henrique Catalani
Octacalcium phosphate (OCP) was synthesized yielding a combination of OCP and hydroxyapatite (HA) with a ratio of 90:10 (OCP/HA). A method was developed to functionalize the surface of the apatite using lauroyl chloride to improve the dispersion of the mineral phase in a poly(L-lactide) (PLLA) polymeric matrix. Infrared spectra and thermal gravimetric analysis confirmed the presence of laurate on the surface of calcium phosphate (CaP) particles. Neat HA particles were also functionalized with lauryl chloride for comparative purposes...
February 6, 2019: Journal of the Mechanical Behavior of Biomedical Materials
https://read.qxmd.com/read/30769232/hydro-air-abrasion-on-dental-glass-ceramics-a-direct-3d-analysis-by-stylus-profilometry
#3
Marco Salerno, Stefano Benedicenti, Angelo Itri
Air abrasion is used in dentistry for cavity opening, post-endodontic cavity cleaning, and removal of hard deposits or stains. Different applications may require different settings. We aimed to gain better understanding of the effect of some operating parameters on the efficiency of air abrasion on a model dental material. We abraded lithium disilicate glass-ceramic blocks (IPS e.max CAD, Ivoclar Vivadent) with Prepstart H2O device (Danville) and 27-µm-size aluminium oxide abrasive (Danville). At 5 bar constant pressure, we varied incidence direction, treatment time, distance, powder consumption, and supporting medium, in separate experiments addressing individual aspects...
February 4, 2019: Journal of the Mechanical Behavior of Biomedical Materials
https://read.qxmd.com/read/30769231/corrosion-and-metal-release-from-overlapping-arterial-stents-under-mechanical-and-electrochemical-stress-an-experimental-study
#4
Paul Johan Høl, Nils R Gjerdet, Torbjörn Jonung
Intra-arterial stenosis due to atherosclerosis is often treated with endovascular balloon dilatation with a metal stent. Restenosis is common and is frequently treated with a new stent placed inside the existing one or the stents are placed with overlap to cover a larger area of the vessels. Observations of stent fractures, stent compression, accumulation of immunocompetent cells around stents have suggested the possibility of immunologic reactions to substances released from stents. An accelerated corrosion model was developed to study corrosion behaviour of commonly used surgical peripheral stents...
February 4, 2019: Journal of the Mechanical Behavior of Biomedical Materials
https://read.qxmd.com/read/30772704/theoretical-analysis-of-nanoshell-assisted-thermal-treatment-for-subcutaneous-tumor
#5
Jingxuan Ma, Xianfeng Yang, Yuxin Sun, Jialing Yang, Jilin Yu
The hyperthermia is an efficient technique for tumor treatment, in which the tumor is subjected to a heating source, such as laser, supersonic or electromagnetic field. In order to improve the therapeutic efficiency and to protect the surrounding healthy tissues, gold nanoshells are embedded in the tumor as the additive to make it absorb more thermal energy than the healthy tissues. In the present study, a one-dimensional three-layered model is established to investigate the thermal response of the bio-tissue in the hyperthermia treatment for subcutaneous tumor...
February 1, 2019: Journal of the Mechanical Behavior of Biomedical Materials
https://read.qxmd.com/read/30776678/material-anisotropy-and-elasticity-of-cortical-and-trabecular-bone-in-the-adult-mouse-femur-via-afm-indentation
#6
Meisam Asgari, Jad Abi-Rafeh, Geoffrey N Hendy, Damiano Pasini
This paper investigates the elastic properties of bone tissue in the adult mouse femur through Atomic Force Microscopy (AFM) indentation with the goal of understanding its microstructure and underlying mechanics at the nano length scale. Both trabecular and cortical bone types are studied. In particular, we examined the elasticity of cortical bone and individual trabeculae in the longitudinal and transverse directions of the samples. For cortical bone, the elastic modulus in the longitudinal direction was found to be 10-15% higher than that in the transverse direction; for trabecular bone, this difference was 42%...
January 31, 2019: Journal of the Mechanical Behavior of Biomedical Materials
https://read.qxmd.com/read/30769234/assessment-of-pcl-carbon-material-scaffolds-for-bone-regeneration
#7
Weiguang Wang, Boyang Huang, Jae Jong Byun, Paulo Bártolo
Biomanufacturing is a relatively new research domain focusing on the use of additive manufacturing technologies, biomaterials, cells and biomolecular signals to produce tissue constructs for tissue engineering. For bone regeneration, researchers are focusing on the use of polymeric and polymer/ceramic scaffolds seeded with osteoblasts or mesenchymal stem cells. However, the design of high-performance scaffolds in terms of mechanical, cell-stimulation and biological performance is still required. This is the first paper investigating the use of an extrusion additive manufacturing system to produce poly(ε-caprolactone) (PCL), PCL/graphene nanosheet (GNS) and PCL/carbon nanotube (CNT) scaffolds for bone applications...
January 31, 2019: Journal of the Mechanical Behavior of Biomedical Materials
https://read.qxmd.com/read/30772703/atomic-force-microscopy-indentation-demonstrates-that-alginate-beads-are-mechanically-stable-under-cell-culture-conditions
#8
Chih-Yao Chui, Andrea Bonilla-Brunner, Jacob Seifert, Sonia Contera, Hua Ye
Alginate microbeads are extensively used in tissue engineering as microcarriers and cell encapsulation vessels. In this study, we used atomic force microscopy (AFM) based indentation using 20 µm colloidal probes to assess the local reduced elastic modulus (E * ) using a novel method to detect the contact point based on the principle of virtual work, to measure microbead mechanical stability under cell culture conditions for 2 weeks. The bead diameter and swelling were assessed in parallel. Alginate beads swelled up to 150% of their original diameter following addition of cell culture media...
January 30, 2019: Journal of the Mechanical Behavior of Biomedical Materials
https://read.qxmd.com/read/30769251/development-and-characterization-of-biological-bovine-dentin-posts
#9
Alice Gonçalves Penelas, Eduardo Moreira da Silva, Laiza Tatiana Poskus, Amanda Cypriano Alves, Isis Ingrid Nogueira Simões, Viviane Hass, José Guilherme Antunes Guimarães
This study aimed at evaluating the use of biological dentin post (BDP), achieved by milling bovine root, through the analyses of mechanical and optical properties. BDPs were compared to a glass fiber post (GFP) in the following tests (n = 10): a) elastic modulus (E) and flexural resistance (σ) by three point bending test; b) fracture resistance (FR) by compressive load at 45° and failure pattern; c) light transmitting (LT) ability and their influence on the resin cement's degree of conversion (DC%); d) bond strength (BS) by push-out test and failure pattern...
January 30, 2019: Journal of the Mechanical Behavior of Biomedical Materials
https://read.qxmd.com/read/30738327/mechanical-behavior-of-metastatic-femurs-through-patient-specific-computational-models-accounting-for-bone-metastasis-interaction
#10
Cristina Falcinelli, Alberto Di Martino, Alessio Gizzi, Giuseppe Vairo, Vincenzo Denaro
This paper proposes a computational model based on a finite-element formulation for describing the mechanical behavior of femurs affected by metastatic lesions. A novel geometric/constitutive description is introduced by modelling healthy bone and metastases via a linearly poroelastic constitutive approach. A Gaussian-shaped graded transition of material properties between healthy and metastatic tissues is prescribed, in order to account for the bone-metastasis interaction. Loading-induced failure processes are simulated by implementing a progressive damage procedure, formulated via a quasi-static displacement-driven incremental approach, and considering both a stress- and a strain-based failure criterion...
January 30, 2019: Journal of the Mechanical Behavior of Biomedical Materials
https://read.qxmd.com/read/30738326/the-effects-of-surface-treatments-on-tensile-bond-strength-of-polyether-ketone-ketone-pekk-to-veneering-resin
#11
George Fokas, Cecilia Yan Guo, James K H Tsoi
OBJECTIVES: To test the different PEKK surface treatment methods on the tensile bond strength (TBS) of a resin composite to PEKK. METHODS: Two hundred and fifty polished PEKK specimens were fabricated, divided into 5 groups (n = 50) and underwent the following treatments: no pre-treatment (control group C), 110 µm Al2 O3 gritblasting at 2 bar for 10 s (Group Al), 98 wt% sulfuric acid etching for 60 s (Group SA), tribochemical silica-coating through air-abrasion with Rocatec Plus 110 µm at 2 bar for 10 s (Group Trib), and sulfuric acid etching and subsequent tribochemical silica-coating (Group SATrib)...
January 30, 2019: Journal of the Mechanical Behavior of Biomedical Materials
https://read.qxmd.com/read/30735979/tough-robust-dual-responsive-nanocomposite-hydrogel-as-controlled-drug-delivery-carrier-of-asprin
#12
Yang Chen, Shuai Kang, Junrong Yu, Yan Wang, Jing Zhu, Zuming Hu
Smart mechanical strong hydrogels have gained increasing attention in the last decade. A novel tough robust biocompatible and dual pH- and temperature- responsive poly (N-isopropylacrylamide)/clay (Laponite XLS)/gold nanoparticles (Au-S-S NPs)/caboxymethyl chitosan (CMCTs) nanocomposite hydrogel was synthesized by a facile one-pot in situ free radical polymerization, using clay and Au-S-S NPs as the cross-linkers instead of toxic organic molecules. By tuning the crucial factors, concentration of Au-S-S NPs, CMCTs and clay, the obtained hydrogels exhibited the highest tensile stress of 535...
January 30, 2019: Journal of the Mechanical Behavior of Biomedical Materials
https://read.qxmd.com/read/30710832/in-vivo-adhesive-behavior-of-human-facial-skin-by-a-modified-indentation-test
#13
A N Dai, W He, S B Wang, W J Chen, C W Li, Z Y Wang, L A Li
A better understanding of the adhesive behavior of human facial skin is important for dermatological or cosmetic applications. For their in vivo experimental characterization and analysis, the indentation test is an effective and widely used method. In this study, our independently developed transparent indenter and curved surface optical imaging technique are improved, by which the contact area of facial skin can be in vivo and in situ obtained during an indentation test. Thanks to the modified indentation technique, the real contact radii of human facial skin under different conditions (normal, as-moistened, moistened after 30 min) are obtained, and their adhesive behavior is studied...
January 26, 2019: Journal of the Mechanical Behavior of Biomedical Materials
https://read.qxmd.com/read/30685725/the-role-of-bacterial-biofilm-and-mechanical-forces-in-modulating-dental-implant-failures
#14
Sathyanarayanan Sridhar, Frederick Wang, Thomas G Wilson, Kelli Palmer, Pilar Valderrama, Danieli C Rodrigues
Currently many assume that bacteria are the primary etiological factor associated with failure of titanium dental implants. However, emerging data indicates a possible role for mechanical forces in implant failure. This study is based on the hypothesis that the synergistic effect of mechanical forces and bacterial biofilm can lead to surface damage resulting in in vivo release of metallic particles. The primary aim of the study was to develop a dynamic fatigue test method for dental implants immersed in wet environments such as; (i) 0...
January 17, 2019: Journal of the Mechanical Behavior of Biomedical Materials
https://read.qxmd.com/read/30738379/finite-element-simulation-of-three-dimensional-residual-stress-in-the-aortic-wall-using-an-anisotropic-tissue-growth-model
#15
Haofei Liu, Ming Zhang, Minliang Liu, Caitlin Martin, Zongxi Cai, Wei Sun
Residual stress is believed to play a significant role in the in vivo stress state of the arterial wall, but quantifying residual stress in vivo is challenging. Based on the well-known assumptions that residual stress is a result of heterogeneous arterial growth and that it homogenizes the transmural distribution of arterial wall stress, we propose a new anisotropic tissue growth model for the aorta to recover the three-dimensional residual stress field in a bi-layer human aortic wall. Finite element simulations showed that the predicted residual stress magnitude with this method are within the documented range for human aorta...
January 16, 2019: Journal of the Mechanical Behavior of Biomedical Materials
https://read.qxmd.com/read/30710831/porous-and-biodegradable-polycaprolactone-borophosphosilicate-hybrid-scaffolds-for-osteoblast-infiltration-and-stem-cell-differentiation
#16
Dibakar Mondal, Shigang Lin, Amin S Rizkalla, Kibret Mequanint
The composition and microstructure of bone tissue engineering scaffolds play a significant role in regulating cell infiltration, proliferation, differentiation, and extracellular matrix production. While boron is an essential trace element for bone formation, growth, and health, boron-containing biomaterials are poorly studied. Specifically, the effect of boron in hybrid scaffolds on stem cell differentiation is unknown. We have previously reported the synthesis and characterization of class II hybrid biomaterials from polycaprolactone and borophosphosilicate glass (PCL/BPSG)...
January 15, 2019: Journal of the Mechanical Behavior of Biomedical Materials
https://read.qxmd.com/read/30739857/structural-chemical-and-mechanical-study-of-tialv-film-on-uhmwpe-produced-by-dc-magnetron-sputtering
#17
J O Berumen, T De la Mora, N López-Perrusquia, I Jiménez-Palomar, S Muhl, C Hernández-Navarro, E García
Ultra High Molecular Weight Polyethylene (UHMWPE), with a semi-trapezoidal topography, and glass samples were coated with a TiAlV film using magnetron sputtering in order to study its structure, chemical composition and the adhesion film properties on the polymer surfaces. The magnetron sputtering is a PVD technique that depending on the deposited parameter produces a coating with structural, chemical and specific topographic characteristics that increase the electrical, mechanical, optical and biological surface properties of the organic compounds...
January 12, 2019: Journal of the Mechanical Behavior of Biomedical Materials
https://read.qxmd.com/read/30685728/wear-of-ceramic-based-dental-materials
#18
Oscar Borrero-Lopez, Fernando Guiberteau, Yu Zhang, Brian R Lawn
An investigation is made of wear mechanisms in a suite of dental materials with a ceramic component and tooth enamel using a laboratory test that simulates clinically observable wear facets. A ball-on-3-specimen wear tester in a tetrahedral configuration with a rotating hard antagonist zirconia sphere is used to produce circular wear scars on polished surfaces of dental materials in artificial saliva. Images of the wear scars enable interpretation of wear mechanisms, and measurements of scar dimensions quantify wear rates...
January 12, 2019: Journal of the Mechanical Behavior of Biomedical Materials
https://read.qxmd.com/read/30685726/shape-recovery-strain-and-nanostructures-on-recovered-polyurethane-films-and-their-regulation-to-osteoblasts-morphology
#19
Juan Xing, Xianchao Pan, Hui Zhang, Jinfeng Wang, Yufei Ma, Yuanliang Wang, Yanfeng Luo
Shape memory polyurethanes (SMPUs) have emerged as novel dynamic substrates to regulate cell alignment, in which recovery-induced change in substrates topography has been described as the major contributor. This work, for the first time, confirmed the pivotal roles of recovery strain and phase-separated nanostructures of SMPUs in regulating cell morphology. SMPU films with different stretching ratios (0%, 50%, 100%, and 200%) were found to produce an average recovery strain from 19.41% to 34.04% within 2 h in dulbecco's modified eagle medium (DMEM)...
January 11, 2019: Journal of the Mechanical Behavior of Biomedical Materials
https://read.qxmd.com/read/30703738/multi-modal-characterization-of-polymeric-gels-to-determine-the-influence-of-testing-method-on-observed-elastic-modulus
#20
David M Kingsley, Caitlin H McCleery, Christopher D L Johnson, Michael T K Bramson, Deniz Rende, Ryan J Gilbert, David T Corr
Demand for materials that mechanically replicate native tissue has driven development and characterization of various new biomaterials. However, a consequence of materials and characterization technique diversity is a lack of consensus within the field, with no clear way to compare values measured via different modalities. This likely contributes to the difficulty in replicating findings across the research community; recent evidence suggests that different modalities do not yield the same mechanical measurements within a material, and direct comparisons cannot be made across different testing platforms...
January 10, 2019: Journal of the Mechanical Behavior of Biomedical Materials
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