Jeniffer Cristóvão Moser, Rita de Cássia Vilhena da Silva, Philipe Costa, Luisa Mota da Silva, Nadla Soares Cassemiro, Arquimedes Gasparotto Junior, Denise Brentan Silva, Priscila de Souza
Plectranthus barbatus , popularly known as Brazilian boldo, is used in Brazilian folk medicine to treat cardiovascular disorders including hypertension. This study investigated the chemical profile by UFLC-DAD-MS and the relaxant effect by using an isolated organ bath of the hydroethanolic extract of P. barbatus (HEPB) leaves on the aorta of spontaneously hypertensive rats (SHR). A total of nineteen compounds were annotated from HEPB, and the main metabolite classes found were flavonoids, diterpenoids, cinnamic acid derivatives, and organic acids...
2023: Cardiovascular Therapeutics