Yizhe Zhao, Shuangchen Li, Lizhi Zhang, Zijian Tang, De Wei, Heng Zhang, Qiong Xie, Huangjian Yi, Xiaowei He
Fluorescence molecular tomography (FMT), as a promising technique for early tumor detection, can non-invasively visualize the distribution of fluorescent marker probe three-dimensionally. However, FMT reconstruction is a severely ill-posed problem, which remains an obstacle to wider application of FMT. In this paper, a two-step reconstruction framework was proposed for FMT based on the energy statistical probability. First, the tissue structural information obtained from computed tomography (CT) is employed to associate the tissue optical parameters for rough solution in the global region...
February 13, 2024: Journal of Biophotonics