Karelle Kouam Yacine Madjo, Marius Mbiantcha, Linda Zenab Njoya Fagni, Vanessa Mba Matah Marthe, Elvira Azanze Ngoufack, Gonzal Eric Tsafack, Stephanie Flore Djuichou Nguemnang, Carine Flore Adjouzem, Gilbert Ateufack
OBJECTIVES: In this study, we determined the gastroprotective and ulcer-healing effects of extracts (aqueous and methanolic) of Nauclea pobeguinii stem-back. METHODS: Gastroprotective and healing activity were evaluated following a HCl/ethanol and an indomethacin-induced acute ulcers models; acetic acid, pylorus-ligature, pylorus ligature/histamine and pylorus ligature/acetylcholine-induced chronic ulcers models. RESULTS: It emerges from this study that, at 100, 200 and 400 mg/kg, the extracts significantly reduced the various ulceration parameters...
June 30, 2023: Journal of Complementary & Integrative Medicine