journal
https://read.qxmd.com/read/38435536/cutaneous-t-cell-lymphoma-and-microbiota-etiopathogenesis-and-potential-new-therapeutic-targets
#1
REVIEW
Daniel Rodríguez Baeza, Lía Bejarano Antonio, Marta González de Arriba, José Antonio Picó-Monllor, Javier Cañueto, Vicente Navarro-Lopez
OBJECTIVE: To review the scientific literature related to human microbiota and cutaneous T-cell lymphoma. Methodology . An exploratory and systematic review of the articles retrieved from the bibliographic databases MEDLINE (PubMed), Embase, The Cochrane Library, and Scopus, published in the last 10 years with the following descriptors: "lymphoma, T-cell, cutaneous," "microbiota," "Mycosis Fungoides," "Sézary Syndrome," "lymphoma, primary cutaneous anaplastic large cell," "Lymphomatoid Papulosis" and "Microbiota," "microbiota," "Microbial Community," and "Microbial Communities...
2024: Dermatology Research and Practice
https://read.qxmd.com/read/38249546/facial-papulopustular-eruption-during-the-covid-19-pandemic-in-patients-treated-with-egfr-inhibitors
#2
JOURNAL ARTICLE
Eleonora De Luca, Pietro Sollena, Lucia Di Nardo, Ettore D'Argento, Emanuele Vita, Giampaolo Tortora, Ketty Peris
Papulopustular rash (PPR) is the most frequent cutaneous adverse event during treatment with epidermal growth factor receptor inhibitors (EGFRis). Although often mild in severity, it can impair patients' quality of life and may also be a reason for discontinuing or changing the dose of the antineoplastic treatment. During COVID-19 pandemics, the use of surgical masks drastically increased and it had an impact on the face skin microenvironment, favoring the worsening of dermatological pathologies. We reported the relapse of PPR in patients treated with EGFR inhibitors who consistently wore face masks (>6 hours/day)...
2024: Dermatology Research and Practice
https://read.qxmd.com/read/38188702/herpes-zoster-after-covid-19-infection-or-vaccination-a-prospective-cohort-study-in-a-tertiary-dermatology-clinic
#3
JOURNAL ARTICLE
Charussri Leeyaphan, Pattriya Jirawattanadon, Sumanas Bunyaratavej, Waratchaya Panjapakkul, Thrit Hutachoke, Yanisorn Nanchaipruek, Phumithep Phumariyapong
BACKGROUND: Herpes zoster (HZ) has been observed to occur after COVID-19 infection and vaccination; however, knowledge regarding the demographic data, clinical presentations, and treatment outcomes of HZ is limited. OBJECTIVE: To compare the demographic data, clinical manifestations, treatments, and outcomes of patients with and without HZ within 14 days of COVID-19 infection or vaccination. METHODS: This prospective cohort study involving patients diagnosed with cutaneous HZ was conducted at a dermatology clinic from October 2021 to January 2023...
2023: Dermatology Research and Practice
https://read.qxmd.com/read/38106989/characterizing-granuloma-annulare-in-73-pediatric-patients
#4
JOURNAL ARTICLE
Ania Stolarczyk, Fatima Bawany, Simon Hernandez, Glynis A Scott, Maria R Cordisco
BACKGROUND: Granuloma annulare (GA) is a common, benign, idiopathic inflammatory dermatosis. Aside from case reports and small studies, there are limited data about the characteristics of GA in children. OBJECTIVE: This study aimed to better characterize the epidemiologic and clinical features, triggering factors, disease associations, and outcomes of GA in the pediatric population. METHODS: We conducted a retrospective study of 73 pediatric patients diagnosed with GA at the University of Rochester Medical Center over a 7-year period...
2023: Dermatology Research and Practice
https://read.qxmd.com/read/37564134/open-label-observational-study-of-a-topical-formulation-of-calcium-spirulan-contained-in-a-defined-extract-of-the-microalga-spirulina-platensis-in-the-treatment-of-children-with-molluscum-contagiosum
#5
JOURNAL ARTICLE
Karoline Jungclaus, Rosa Mascarenhas, Oscar Tellechea, Jeremias L K Reich, Kristian Reich
BACKGROUND: Molluscum contagiosum (MC) is a common viral skin infection primarily affecting children which is difficult to treat using available therapeutic approaches. The sulfated polysaccharide named calcium spirulan (Ca-SP) has demonstrated antiviral effects against herpes simplex virus in keratinocytes in vitro , and a cream containing 1.5% Ca-SP and 1% of a defined microalgae extract (Spiralin® ) effectively prevented herpes labialis in a trial with susceptible individuals...
2023: Dermatology Research and Practice
https://read.qxmd.com/read/37564133/glove-induced-hand-dermatitis-a-study-in-healthcare-workers-during-covid-19-pandemic-in-indonesia
#6
JOURNAL ARTICLE
Cita Rosita Sigit Prakoeswa, Damayanti, Sylvia Anggraeni, Menul Ayu Umborowati, Fajar Waskito, Niken Indrastuti, Sri Awalia Febriana, Agnes Rosarina Prita Sari, Kristo Alberto Nababan, Cut Putri Hazlianda, Nopriyati, Windy Keumala Budianti, Miranti Pangastuti, Faridha Ilyas, Agnes Kartini, Nurwestu Rusetiyanti, Ika Anggraini, Idrianti Idrus, Herwinda Brahmanti, Gardenia Akhyar
Skin damage among healthcare workers has been reported by many centers around the world. Occupational hand dermatitis is one of the most commonly known occupational skin diseases and a socially significant health issue. The use of gloves is one of the risk factors for the occurrence and/or aggravation of hand dermatitis. This cross-sectional study involved healthcare workers in 14 referral hospitals for COVID-19 throughout Indonesia. Questionnaires were distributed to the participants, which consisted of the subject's characteristics, glove-related skin problems, history of glove use, and clinical history...
2023: Dermatology Research and Practice
https://read.qxmd.com/read/37546347/ultrasonographic-characteristics-in-the-fingers-and-other-superficial-glomus-tumours
#7
JOURNAL ARTICLE
Noboru Takanashi, Satomi Asai, Yoko Ogase, Akiko Fujii, Haruyo Atsumi, Mika Doi, Nobue Kumaki, Tomotaka Mabuchi, Hayato Miyachi
Glomus tumours are painful superficial tumours, and ultrasonography is an extremely useful and noninvasive diagnostic technique for superficial organs. In this study, we retrospectively examined glomus tumours using ultrasonography. Among 18 patients histopathologically diagnosed with glomus tumours via ultrasonography, we observed five different development sites: subungual areas or those surrounding the nail bed (12), other areas on the finger surface (3), abdominal wall (1), upper arm (1), and forearm (1)...
2023: Dermatology Research and Practice
https://read.qxmd.com/read/37520456/effectiveness-of-three-types-of-moisturizers-on-senile-dry-skin-a-randomized-controlled-pilot-trial
#8
JOURNAL ARTICLE
Miku Aoki, Natsuki Hata, Junko Yotsuya
BACKGROUND: For dry skin, the application of a hypoallergenic moisturizer twice daily is recommended in elderly individuals. However, it is not known which is the most effective and appropriate moisturizer among the commercially available moisturizers. AIMS: In this study, we aimed to investigate the efficacy of the three widely used moisturizers for the treatment of senile dry skin. Patients/Methods . This interventional study involved elderly individuals aged >65 years who were living in a nursing home...
2023: Dermatology Research and Practice
https://read.qxmd.com/read/37223320/dermoscopic-features-of-psoriatic-nails-and-their-correlation-to-disease-severity
#9
JOURNAL ARTICLE
Zeinab R Mashal, Emad Eldin A Elgamal, Mohamed S Zaky, Mohamed L Elsaie
BACKGROUND: Nail psoriasis is a challenging chronic condition affecting patients functionally and psychologically. Nail involvement is observed in 15-80% of psoriatic patients with occasional presence of isolated nail psoriasis. OBJECTIVES: To evaluate dermoscopic features of nail psoriasis and correlate them clinically. METHODS: The study included fifty subjects with nail psoriasis. Psoriasis skin and nail severity was evaluated using psoriasis area severity index (PASI) and nail psoriasis severity index (NAPSI)...
2023: Dermatology Research and Practice
https://read.qxmd.com/read/37206671/severe-cutaneous-adverse-drug-reactions-at-a-tertiary-care-center-in-saudi-arabia
#10
JOURNAL ARTICLE
Mohammed I AlJasser
BACKGROUND: Severe cutaneous adverse drug reactions (SCARs), although rare, are known to be associated with significant morbidity and mortality. SCARs include drug reaction with eosinophilia and systemic symptoms (DRESS), Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN), and acute generalized exanthematous pustulosis (AGEP). Studies on SCARs are limited in Saudi Arabia. This study aims to characterize SCARs at a tertiary care center in Saudi Arabia. METHODS: A cross-sectional study was conducted at King Abdulaziz Medical City, Riyadh, Saudi Arabia...
2023: Dermatology Research and Practice
https://read.qxmd.com/read/37206670/interleukin-15-and-tumor-necrosis-factor-%C3%AE-in-iraqi-patients-with-alopecia-areata
#11
JOURNAL ARTICLE
Zainab A Kamil, Galawish A Abdullah, Haider Hashim Zalzala
BACKGROUND: Alopecia areata (AA) is a common form of noncicatricial hair loss of unknown cause, affecting 0.1-0.2% of the general population. Most evidence supports the hypothesis that it is disease of the hair follicle of autoimmune nature mediated by T-cells, with important cytokine role. Objective of the Study . The objective of this study is to study the association and changes in serum levels of interleukin-15 (IL-15) and tumor necrosis factor- α (TNF- α ) in patients with AA in relation to the type, activity, and disease duration...
2023: Dermatology Research and Practice
https://read.qxmd.com/read/36846564/dupilumab-direct-cost-and-clinical-evaluation-in-patients-with-atopic-dermatitis
#12
JOURNAL ARTICLE
Marco Ferrari, Matthew G Donadu, Gabriele Biondi, Laura Saderi, Federica Sucato, Maria A Montesu, Paola Ruggiu, Paola Merella, Carla Chessa, Angela Sias, Gabriella Carmelita, Vittorio Mazzarello, Giovanni Sotgiu, Satta Rosanna
Health care spending in Italy is high and continues to increase; assessing the long-term health and economic outcomes of new therapies is essential. Atopic dermatitis (AD) is a chronic, pruritic, immune-mediated inflammatory dermatosis, a clinical condition that significantly affects patients' quality of life at a high cost and requires continuous care. This retrospective study aimed to assess the direct cost and adverse drug reactions (ADRs) of Dupilumab and patients' clinical outcomes. All AD patients treated with Dupilumab at the Sassari University Hospital, Italy, between January 2019 and December 2021 were included...
2023: Dermatology Research and Practice
https://read.qxmd.com/read/36762366/suggested-guidelines-for-the-treatment-of-mycosis-fungoides-in-countries-with-limited-resources
#13
REVIEW
Mona Abdel-Halim Ibrahim, Nada Eltayeb, Mirna Michel Ibrahim, Ahmed Nassar, Maged Daruish, Maha El-Zimaity, Mahmoud El-Lithy, Ahmed Mostafa, Amal El-Afifi, Haitham Abdelbary, Mahira Hamdy El-Sayed
The treatment options for mycosis fungoides (MF) have been expanding but unfortunately many of the currently used treatment modalities are unavailable in Egypt and other African/Arab countries. In addition, there is a lack of consensus on the treatment of hypopigmented MF (HMF), which is a frequently encountered variant in our population. We aimed to develop regional treatment guidelines based on the international guidelines but modified to encompass the restricted treatment availability and our institutional experience...
2023: Dermatology Research and Practice
https://read.qxmd.com/read/36714681/differential-expression-of-claudin-1-and-4-in-basal-cell-carcinoma-of-the-skin
#14
JOURNAL ARTICLE
T Nakazawa, A Hasegawa, T Nagasaka, K Yoshida, F Guo, D Wu, K Hiroshima, M Takeuchi
Basal cell carcinoma (BCC) is the most common human malignancy. The biological behavior of this entity is remarkably indolent. Claudin plays an important role in tight junctions, regulating paracellular passage of variable substance including growth factors and maintaining the polarity of epithelia. Up- or downregulated claudin expression has been reported in many cancers. Nevertheless, claudin expression in BCC of the skin remains unclear. We therefore examined the status of claudin 1 and 4 expressions in BCC and adjacent normal skin by immunohistochemistry (IHC)...
2023: Dermatology Research and Practice
https://read.qxmd.com/read/36590106/designing-a-band-for-vehicles-drivers-induced-by-ultraviolet-and-infrared-radiations
#15
JOURNAL ARTICLE
Nouf Jubran AlQahtani, Amnah Nabil Bukair, Ghada Naje Alessa, Hoor Fayez AlDushaishi, Syed Mehmood Ali
BACKGROUND: Solar radiations that reach the Earth can be divided into ultraviolet, visible light, and infrared. Overexposure to these radiations can facilitate adverse skin diseases such as sunburn, skin cancer, and photoaging. People who drive vehicles for an extended period are likely to develop skin cancer in the exposed body area. METHOD: This research proposes a wearable protective device around the upper arm to measure the transmitted radiation through the front and the side windows...
2022: Dermatology Research and Practice
https://read.qxmd.com/read/36254319/comparative-efficacy-study-combination-of-oral-methotrexate-and-prednisolone-versus-oral-methotrexate-in-patients-with-lichen-planopilaris
#16
JOURNAL ARTICLE
Farahnaz Fatemi, Farifteh Esfahanian, Ali Asilian, Fatemeh Mohaghegh, Mina Saber
BACKGROUND: Lichen planopilaris (LPP) is a rare inflammatory disorder of the scalp that causes cicatricial alopecia. No therapeutic approach has been approved for this disease due to the rare frequency. Methotrexate and corticosteroid are commonly considered second- or third-line therapy. The efficacy of a combination of methotrexate and corticosteroid has been reported in some dermatological and immunological diseases. However, the efficacy of this combination in LPP is not clear. Therefore, this study aimed to compare the impact of methotrexate alone and in combination with corticosteroid on LPP...
2022: Dermatology Research and Practice
https://read.qxmd.com/read/36249714/the-efficacy-of-lactocare%C3%A2-synbiotic-on-the-clinical-symptoms-in-patients-with-psoriasis-a-randomized-double-blind-placebo-controlled-clinical-trial
#17
JOURNAL ARTICLE
Ali Akbarzadeh, Pedram Alirezaei, Amin Doosti-Irani, Maryam Mehrpooya, Fatemeh Nouri
Background: Attention to the administration of probiotics for the treatment of psoriasis has recently increased. Aim: In the present study, improvements in dermatology life quality index (DLQI), psoriasis area severity index (PASI), and visual analogue scale (VAS) scores in the psoriasis patients receiving Lactocare® probiotic were compared to psoriasis patients receiving placebo. Methods: A total of 52 psoriasis patients were included in this study and randomly divided into treatment and placebo (control) groups...
2022: Dermatology Research and Practice
https://read.qxmd.com/read/36193055/fordyce-angiokeratoma-comparison-of-cryotherapy-and-electrocauterization-treatments
#18
JOURNAL ARTICLE
Necmi Bayraktar
Fordyce angiokeratoma is a benign lesion commonly developing on the scrotal skin. The incidence increases with age. About half of these lesions may be symptomatic and frequently cause itching and bleeding. Although the treatment is not always considered necessary, several treatment methods are used for symptomatic cases, especially for cosmetic purposes. Treatment options include surgical excision, laser ablation, electrocoagulation, cryotherapy, and sclerotherapy. The most widely used methods are electrocoagulation and cryotherapy...
2022: Dermatology Research and Practice
https://read.qxmd.com/read/36092493/profile-of-transepidermal-water-loss-tewl-skin-hydration-and-skin-acidity-ph-in-indonesian-batik-workers
#19
JOURNAL ARTICLE
Cita Rosita Sigit Prakoeswa, Damayanti, Sylvia Anggraeni, Menul Ayu Umborowati, Sri Awalia Febriana, Katharina Oginawati, Ikeu Tanziha
Chemical substances used during batik processing may affect the physiological function of the batik worker's skin barrier. This study assessed the level of transepidermal water loss (TEWL), skin hydration, and skin acidity in 61 batik workers from the batik center in Paseseh village, Tanjung Bumi subdistrict, Madura Island, Indonesia. Forty-five batik workers involved in dry work including drawing patterns on the cloth with wax and sixteen batik workers involved in wet work including dyeing the cloth with a dye bath were included in this study...
2022: Dermatology Research and Practice
https://read.qxmd.com/read/36017173/development-and-validation-of-a-simple-model-to-predict-the-risk-of-nonmelanoma-skin-cancer-on-screening-total-body-skin-examination
#20
JOURNAL ARTICLE
Rebecca I Hartman, Yun Xue, Ryan Karmouta, Elizabeth Tkachenko, Sara J Li, David G Li, Cara Joyce, Arash Mostaghimi
Objective: There is insufficient evidence to generate skin cancer screening guidelines at the population level, resulting in arbitrary variation in patient selection for screening skin examinations. This study was aimed at developing an easy-to-use predictive model of nonmelanoma skin cancer (NMSC) risk on screening total body skin examination (TBSE). Methods: This epidemiologic assessment utilized data from a prospective, multicenter international study from primarily academic outpatient dermatology clinics...
2022: Dermatology Research and Practice
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