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Clinical Schizophrenia & related Psychoses

Sean Nutting, Christopher Martin, Richard Prensner, Andrew Francis, Alfredo Bellon
Wolff-Parkinson-White syndrome (WPW) is a cardiac conduction abnormality characterized by ventricular contractions that appear sooner than the usual interval regulated by the atrioventricular (AV) node. It is commonly asymptomatic but in rare cases can lead to sudden cardiac death. Little is known about the cardiac effects of antipsychotics on patients with WPW. Here we review all the published information currently available on the use of neuroleptics in patients with this cardiac conduction anomaly. Only a few case reports and one controlled study have been published in this area...
January 3, 2019: Clinical Schizophrenia & related Psychoses
Isabelly Sanally Monteiro Florentino, Catarina de Moraes Braga, Leonardo Machado, Rodrigo Cavalcanti Machado da Silva
No abstract text is available yet for this article.
January 3, 2019: Clinical Schizophrenia & related Psychoses
Tânia Abreu, Joana Pinheiro
INTRODUCTION: Aripiprazole is an antipsychotic used in the treatment of different disorders. The most common side effects are dizziness, insomnia, akathisia, activation, nausea and vomiting. Ophthalmologic side effects are rare. We report a case of myopia induced by aripiprazole. METHODS: Case study and literature review on aripiprazole-induced myopia. RESULTS: a 21-year-old male, with a first psychotic episode, developed myopia two weeks after initiating aripiprazole 20 mg/day...
January 3, 2019: Clinical Schizophrenia & related Psychoses
Aimee Murray, Kris Svendahl, Susanne Lee, Ian S Ramsay, Marc E Mooney
Despite effective pharmacotherapy for positive symptoms of psychosis, cognitive deficits emerge early and are persistent. Efficacy studies have demonstrated cognitive training can produce improvement in cognition, symptoms, and functional outcomes for psychosis. A chart review of seventy-one first episode psychosis patients in a cognitive training program was designed to determine feasibility and effectiveness of the program in a non-research clinic setting. Cognitive testing data, symptom change, and re-hospitalization data were reviewed...
January 3, 2019: Clinical Schizophrenia & related Psychoses
Joanna Fox
No abstract text is available yet for this article.
January 3, 2019: Clinical Schizophrenia & related Psychoses
Alexander Dufort, Robert B Zipursky
Schizophrenia is a chronic, debilitating and costly illness. The course of illness is often exacerbated by relapses which are associated with negative outcomes including rehospitalisation. The most important risk factor associated with relapse is medication nonadherence. Medication nonadherence is not specific to schizophrenia and is an issue across all of medicine. The objective of this paper is to present a narrative review which synthesizes the rates and predictors of medication nonadherence, as well as associated interventions, across schizophrenia, first episode psychosis and general medicine...
January 3, 2019: Clinical Schizophrenia & related Psychoses
Nujsaubnusi C Vue, Quentin Gabor
The Cultural Formulation Interview (CFI) is an assessment tool created and intended for provider use to improve culturally appropriate care. We present a case in which portions of the CFI were used to help a care team better understand the diagnosis and culture of a patient with schizophrenia.
January 3, 2019: Clinical Schizophrenia & related Psychoses
Peter F Buckley
No abstract text is available yet for this article.
2019: Clinical Schizophrenia & related Psychoses
(no author information available yet)
No abstract text is available yet for this article.
2019: Clinical Schizophrenia & related Psychoses
P Vasileiadis, G Mavridis, A Keramidas, D Chardalidou, I Pervos, C Charalampous
BACKGROUND: Chilaiditi's sign is defined as the interposition of bowels between the liver and the right diaphragm. When the patient is symptomatic due to the intestinal obstruction, the case is referred to as Chilaiditi's syndrome. OBJECTIVE: To emphasize the importance of accurate diagnose of Chilaiditi's syndrome in patients with psychotic disturbances. METHOD: A 46 years old male was admitted to our department suffering from a constant epigastric and right upper quadrant pain with radiation to the right shoulder...
June 26, 2018: Clinical Schizophrenia & related Psychoses
Steven Berendsen, Jasper van der Paardt, Marion van Bruggen, Hans Nusselder, Margje Jalink, Jaap Peen, Henricus Van, Jack Dekker, Lieuwe de Haan
OBJECTIVE: clinical staging and profiling of schizophrenia spectrum disorders has been proposed to describe and define the heterogenous course of disease. We examined the construct validity of clinical staging in schizophrenia spectrum disorders by measuring differences in distribution and severity of relevant clinical profilers and therapeutic improvement (HoNOS) across clinical stages. METHODS: we performed a prospective cross-sectional study with 258 inpatiënts who met DSM-IV criteria for schizophrenia spectrum disorders, recruited in an acute ward of a psychiatric hospital from 1-1-2015 until 31-12-2016...
June 26, 2018: Clinical Schizophrenia & related Psychoses
Ciaran Clarke
Although recognized as a feature of schizophrenia since the time of Kraepelin, motor disorders have received relatively little attention, particularly as regard their phenomenology. This is particularly the case in the English-speaking literature, where 'automaticity', mutism, and autonomic instability, have been emphasized among the features of catatonia at the expense of more complex behaviors and mannerisms. The possible relationship between the content of thinking disorders, such as hallucinations and dereistic thinking, and involuntary and semi-voluntary movement disorders, has been little noted...
June 26, 2018: Clinical Schizophrenia & related Psychoses
Camila Wanderley Pereira, Isabelly Sanally Monteiro Florentino, Leonardo Machado
Cotard's Syndrome (CS), among the noncognitive changes in the forms of dementia, is a seldom-found manifestation (1). This syndrome is characterized by the delusion of having lost organs (the individual experiences huge changes in the body and believes that he/she no longer has one or more organs) and by nihilistic delusion (the individual believes he/she or everyone in the world has died or been destroyed) (2). In 1880, Jules Cotard (1840-1889) described a clinical condition that he believed corresponded to a new subtype of depression, which he called anxious melancholia...
June 26, 2018: Clinical Schizophrenia & related Psychoses
Cintia R Prokopez, Oscar M Cesoni, Gabriela B Caporusso, María L Reffino-Pereyra, Germán Alberio, Miguel Vallejos
Patients with schizophrenia have higher rates of adverse childhood experiences (ACEs) than the general population, and those who suffered multiple traumatic experiences have a higher prevalence of positive symptoms, poorer social functioning and more suicidal ideations and behavior. The current study aims to determine the prevalence of ACEs in a female patient sample with schizophrenia. An observational descriptive cross-sectional study was conducted. Participants included 50 female patients older than 18 years, with schizophrenia...
June 26, 2018: Clinical Schizophrenia & related Psychoses
Mina Boazak, Benjamin Kahn, Lindsay Cox, James Ragazino, David R Goldsmith, Robert O Cotes
Clozapine-induced neutropenia occurs in 3-5% of individuals treated with clozapine. Current US guidelines require interruption of clozapine when the absolute neutrophil count (ANC) drops below 1000 cells/mm3 . There is minimal available guidance for what dosing schedule to use when restarting clozapine after an episode of neutropenia. Here, we present a case of a 50-year-old Caucasian female with a history of schizoaffective disorder who was successfully rechallenged on clozapine one month after developing clozapine-induced neutropenia (ANC 600 cells/mm3 )...
June 26, 2018: Clinical Schizophrenia & related Psychoses
Isabelly Sanally Monteiro Florentino, José Brasileiro Dourado Júnior, Amaury Cantilino
BACKGROUND: The involvement of Cryptococcus as an etiological agent in behavioral disorders, such as psychosis, is rare finding. METHODS: We report the case of 20-year-old man showed apparent functioning behavior premorbid, immunocompetent, with had a first psychotic episode one day after a clinical condition by mild fever, polyarthralgia, headache, fatigue and insomnia and detected cryptococcal antigen latex and India ink positive for Cryptococus neoformans in lumbar puncture...
June 26, 2018: Clinical Schizophrenia & related Psychoses
Ricardo Coentre, Rodrigo Saraiva, Pedro Levy
Hypokalemia is the most frequent electrolyte abnormality seen in clinical practice. Hypokalemia is defined as serum potassium below 3.5 mEq/L and is usually asymptomatic and only identified in routine laboratory analysis. However, in some cases, symptoms include hypertension, palpitations, muscle weakness, easy fatigability, cramping and myalgias, memory impairment, disorientation and confusion, depressed or anxious mood, and irritability. Although rare, hypokalemia has been associated with psychosis. In particular, hypokalemia has been associated with psychotic exacerbations in patients with chronic psychotic disorder...
June 26, 2018: Clinical Schizophrenia & related Psychoses
Massimiliano Buoli, Chiara Rovera, Cecilia Maria Esposito, Silvia Grassi, Wiepke Cahn, A Carlo Altamura
Aggressive behaviour represents a challenge in the treatment of patients with schizophrenia, being often associated with clinical predictors of severity of illness such as poor insight, psychotic re-exacerbation, concomitant substance misuse or comorbidity with personality disorders. As psychotic relapses and consequent risk of aggressive behaviour are often associated with a poor compliance, purpose of the present manuscript is to give an overview of the available data about the use of depot antipsychotics for the management of violence in patients with schizophrenia...
June 26, 2018: Clinical Schizophrenia & related Psychoses
Barbara Schwartz, Theresa Teslovich, Xiaozhen You, Jae Cho, Nina Schooler, Peter Kokkinos, Chandan Vaidya
Memory impairment in schizophrenia has been linked to abnormal functioning of fronto-temporal networks. In this pilot study, we investigated whether 12-weeks of exercise improved hippocampal-dependent memory functions and resting-state functional connectivity in middle-aged adults with schizophrenia. The exercise regimen was feasible, well-attended, and safe. There was a pre- to post-intervention increase in spatial memory accuracy that was correlated to an increase in hippocampal-prefrontal cortex connectivity...
June 26, 2018: Clinical Schizophrenia & related Psychoses
Mar Fernández-Modamio, Marta Arrieta-Rodríguez, Rosario Bengochea-Seco, Iciar Santacoloma-Cabero, Juan Gómez de Tojeiro-Roce, Bárbara García-Polavieja, Eduardo González-Fraile, Manuel Martín-Carrasco, Kim Griffin, David Gil-Sanz
Previous research on theory of mind suggests that people with schizophrenia have difficulties with complex mentalization tasks that involve the integration of cognition and affective mental states. One of the tools most commonly used to assess theory of mind is the Faux-Pas Test. However, it presents two main methodological problems: 1) the lack of a standard scoring system; 2) the different versions are not comparable due to a lack of information on the stories used. These methodological problems make it difficult to draw conclusions about performance on this test by people with schizophrenia...
June 26, 2018: Clinical Schizophrenia & related Psychoses
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