journal
Journals Current Opinion in Endocrinolo...

Current Opinion in Endocrinology, Diabetes, and Obesity

https://read.qxmd.com/read/38587099/the-interaction-between-gut-microbiome-and-bone-health
#1
JOURNAL ARTICLE
Francesco Inchingolo, Angelo Michele Inchingolo, Fabio Piras, Laura Ferrante, Antonio Mancini, Andrea Palermo, Alessio Danilo Inchingolo, Gianna Dipalma
PURPOSE OF REVIEW: This review critically examines interconnected health domains like gut microbiome, bone health, interleukins, chronic periodontitis, and coronavirus disease 2019 (COVID-19), offering insights into fundamental mechanisms and clinical implications, contributing significantly to healthcare and biomedical research. RECENT FINDINGS: This review explores the relationship between gut microbiome and bone health, a growing area of study. It provides insights into skeletal integrity and potential therapeutic avenues...
April 12, 2024: Current Opinion in Endocrinology, Diabetes, and Obesity
https://read.qxmd.com/read/38533785/gut-motility-and-hormone-changes-after-bariatric-procedures
#2
JOURNAL ARTICLE
Khushboo Gala, Wissam Ghusn, Barham K Abu Dayyeh
PURPOSE OF REVIEW: Metabolic and bariatric surgery (MBS) and endoscopic bariatric therapies (EBT) are being increasingly utilized for the management of obesity. They work through multiple mechanisms, including restriction, malabsorption, and changes in the gastrointestinal hormonal and motility. RECENT FINDINGS: Roux-en-Y gastric bypass (RYGB) and laparoscopic sleeve gastrectomy (LSG) cause decrease in leptin, increase in GLP-1 and PYY, and variable changes in ghrelin (generally thought to decrease)...
March 28, 2024: Current Opinion in Endocrinology, Diabetes, and Obesity
https://read.qxmd.com/read/38511400/gut-hormones-and-appetite-regulation
#3
JOURNAL ARTICLE
So-Hyeon Hong, Kyung Mook Choi
PURPOSE OF REVIEW: Various gut hormones interact with the brain through delicate communication, thereby influencing appetite and subsequent changes in body weight. This review summarizes the effects of gut hormones on appetite, with a focus on recent research. RECENT FINDINGS: Ghrelin is known as an orexigenic hormone, whereas glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), cholecystokinin (CCK), postprandial peptide YY (PYY), and oxyntomodulin (OXM) are known as anorexigenic hormones...
March 22, 2024: Current Opinion in Endocrinology, Diabetes, and Obesity
https://read.qxmd.com/read/38483115/potassium-competitive-acid-blockers-and-acid-related-disorders
#4
JOURNAL ARTICLE
Kevin Z Huang, H Christian Weber
PURPOSE OF THE REVIEW: Potassium-competitive acid blockers (PCABs) represent a new class of compounds for the treatment of acid-related disorders. Recent FDA approval of the PCAB vonoprazan for erosive esophagitis has started an important new approach to acid-related disorders. RECENT FINDINGS: Compared to conventional proton pump inhibitors (PPIs), PCABs provide more rapid, potent, and sustained suppression of gastric acid with faster and more durable symptom relief...
March 15, 2024: Current Opinion in Endocrinology, Diabetes, and Obesity
https://read.qxmd.com/read/38334488/apoc3-sirna-and-aso-therapy-for-dyslipidemia
#5
JOURNAL ARTICLE
Jasmine Chebli, Miriam Larouche, Daniel Gaudet
PURPOSE OF REVIEW: The aim of this review is to present the clinical indications of apolipoprotein C-III (apoC3) inhibition in the therapeutic arsenal for the treatment of lipid disorders and associated risks and to compare the most advanced modalities of apoC3 inhibition currently available or in development, specifically APOC3 antisense oligonucleotides (ASO) and small interfering RNA (siRNA). RECENT FINDINGS: ApoC3 inhibition significantly decreases triglyceride levels by mechanisms coupling both lipoprotein lipase (LPL) upregulation and LPL-independent mechanisms...
February 12, 2024: Current Opinion in Endocrinology, Diabetes, and Obesity
https://read.qxmd.com/read/38411440/addressing-genetic-and-environmental-sources-of-cardiometabolic-disease
#6
JOURNAL ARTICLE
Gerald F Watts, Dick C Chan
No abstract text is available yet for this article.
April 1, 2024: Current Opinion in Endocrinology, Diabetes, and Obesity
https://read.qxmd.com/read/38411439/editorial-introduction
#7
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
April 1, 2024: Current Opinion in Endocrinology, Diabetes, and Obesity
https://read.qxmd.com/read/38095480/bempedoic-acid-a-new-player-for-statin-intolerant-patients-and-beyond
#8
REVIEW
Salvatore Giordano, Carmen Anna Maria Spaccarotella, Giovanni Esposito, Ciro Indolfi
PURPOSE OF REVIEW: Low-density lipoproteins (LDL) cause atherosclerotic cardiovascular disease, a condition associated with significant morbidity and mortality. Statins represent the cornerstone for preventing cardiovascular events in patients with elevated LDL-cholesterol (LDL-C) levels, however, they are associated with frequent musculoskeletal adverse effects, which lead to drug discontinuation or limit their use to low (and less effective) doses. Bempedoic acid (BA) is a newly approved, safe, cholesterol-lowering agent that inhibits ATP-citrate lyase, an enzyme upstream to 3-hydroxy-3-methyl-glutaryl-CoA (HMG-CoA) reductase, the target of statins...
April 1, 2024: Current Opinion in Endocrinology, Diabetes, and Obesity
https://read.qxmd.com/read/37994661/multifactorial-chylomicronemia-syndrome
#9
REVIEW
Alan Chait
PURPOSE OF REVIEW: The aim of this review was to understand the role of multifactorial chylomicronemia syndrome (MFCS) as a cause of severe hypertriglyceridemia; to distinguish it from other causes of severe hypertriglyceridemia; and to provide a rational approach to treatment. RECENT FINDINGS: There have been advances in understanding the genetic underpinning of MFCS, and a better appreciation as to how to differentiate it from the much rarer familial chylomicronemia syndrome, in which there are substantial differences in the approach to their treatment...
April 1, 2024: Current Opinion in Endocrinology, Diabetes, and Obesity
https://read.qxmd.com/read/38126111/when-history-law-and-medicine-intersect
#10
JOURNAL ARTICLE
Lynne L Levitsky
No abstract text is available yet for this article.
February 1, 2024: Current Opinion in Endocrinology, Diabetes, and Obesity
https://read.qxmd.com/read/38047549/endocrine-features-of-primary-mitochondrial-diseases
#11
REVIEW
Lindsay Romo, Nina B Gold, Melissa A Walker
PURPOSE OF REVIEW: Primary mitochondrial diseases are one of the most prevalent groups of multisystem genetic disorders. Endocrinopathies associated with mitochondrial diseases may have clinical features that are distinct from the more common forms. We provide an overview of mitochondrial disorder genetics and phenotypes, focusing on recent studies regarding identification and treatment of associated endocrinopathies. RECENT FINDINGS: Known endocrine phenotypes of mitochondrial disorders continue to expand, and now include growth hormone deficiency, hypogonadism, precocious puberty, hypoparathyroidism, hypo- and hyperthyroidism, diabetes, and adrenal insufficiency...
February 1, 2024: Current Opinion in Endocrinology, Diabetes, and Obesity
https://read.qxmd.com/read/37902122/adherence-to-pharmacotherapy-sine-qua-non-for-reducing-cumulative-risk-of-premature-coronary-disease-in-familial-hypercholesterolemia
#12
REVIEW
Jing Pang, Frank M Sanfilippo, Dick C Chan, Gerald F Watts
PURPOSE OF REVIEW: Familial hypercholesterolemia (FH) is a dominant and highly penetrant monogenic disorder present from birth that markedly elevates plasma low-density lipoprotein (LDL)-cholesterol concentration and, if untreated, leads to atherosclerotic cardiovascular disease (ASCVD). The risk of ASCVD can be substantially reduced with lipid-lowering treatment (LLT). However, adherence to LLT remains a major challenge in FH patients and an under-recognized issue. We review several barriers to treatment adherence and implementation strategies for improving adherence in patients with FH...
February 1, 2024: Current Opinion in Endocrinology, Diabetes, and Obesity
https://read.qxmd.com/read/37820077/treating-obesity-in-type-1-diabetes-mellitus-review-of-efficacy-and-safety
#13
REVIEW
Matthew Freeby, Kyrstin Lane
PURPOSE OF REVIEW: Obesity is an epidemic in the United States with serious concomitant co-morbid conditions; people living with type 1 diabetes mellitus (T1D) are not immune to the risk either. Weight gain in T1D is likely multifactorial, due to genetic, environmental and treatment-related factors. FDA-approved and other adjunctive weight loss therapies may benefit people living with T1D but there are risks to consider when providing recommendations or prescribing medications. RECENT FINDINGS: We performed a PubMed search of studies assessing clinical outcomes of both approved and off-label medications used in the treatment of type 1 diabetes...
February 1, 2024: Current Opinion in Endocrinology, Diabetes, and Obesity
https://read.qxmd.com/read/38054472/assessing-the-contribution-of-plastic-associated-obesogenic-compounds-to-cardiometabolic-diseases
#14
JOURNAL ARTICLE
Jacob Warger, Michaela Lucas, Andrew Lucas
PURPOSE OF REVIEW: To present recent evidence that strengthens the concept that exogenous pollutants contribute to adipose dysfunction and increased rates of disease and to highlight the ineffective regulation of this risk as industry switches to related but similarly toxic variants. RECENT FINDINGS: Substitutes for common phthalates and the highly regulated bisphenol A (BPA) show similar deleterious effects on adipocytes. The well tolerated limit for BPA exposure has been reduced in Europe to below the level detected in recent population studies...
December 7, 2023: Current Opinion in Endocrinology, Diabetes, and Obesity
https://read.qxmd.com/read/37872797/editorial-introductions
#15
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
December 1, 2023: Current Opinion in Endocrinology, Diabetes, and Obesity
https://read.qxmd.com/read/37678163/glucagon-like-peptide-1-receptor-agonists-and-safety-in-the-preconception-period
#16
REVIEW
Evelyn Minis, Fatima Cody Stanford, Shruthi Mahalingaiah
PURPOSE OF REVIEW: Glucagon-like peptide-1 (GLP-1) receptor agonists (RAs) are becoming increasingly popular for the treatment of type II diabetes and obesity. Body mass index (BMI) thresholds at in vitro fertilization (IVF) clinics may further drive the use of these medications before infertility treatment. However, most clinical guidance regarding optimal time to discontinue these medications prior to conception is based on animal data. The purpose of this review was to evaluate the literature for evidence-based guidance regarding the preconception use of GLP-1 RA...
December 1, 2023: Current Opinion in Endocrinology, Diabetes, and Obesity
https://read.qxmd.com/read/37603031/systematic-reviews-and-meta-analyses-on-androgen-administration-in-humans-an-umbrella-review
#17
JOURNAL ARTICLE
Razieh Chegeni, Ståle Pallesen, Hailemariam Weldemariam, Dominic Sagoe
PURPOSE OF REVIEW: The present umbrella review systematically searches and synthesizes recent (2021-2023) systematic reviews and meta-analyses (SRMA) on androgen administration in humans. RECENT FINDINGS: Results from 19 SRMA are synthesized. Four themes were identified: market for androgens, prevalence of androgen abuse, psychological effects of androgens, and clinical/therapeutic effects of androgens. One of three androgens on the illicit market are fake or substandard...
December 1, 2023: Current Opinion in Endocrinology, Diabetes, and Obesity
https://read.qxmd.com/read/37578378/nutrition-and-thyroid-disease
#18
JOURNAL ARTICLE
Leonidas H Duntas
PURPOSE OF REVIEW: The aim of this review was to determine, based on the most recent findings, the involvement of trace elements and vitamins critical for thyroid function and combating thyroid disease. RECENT FINDINGS: Nutritional guidance is pivotal to reducing the risk of thyroid disease and to managing it when it arises, this meaning the prescription of diets rich in such micronutrients as iodine, selenium, iron, zinc, and vitamins B12, D3, and A. Most of the above micronutrients are good antioxidants, building up an anti-inflammatory profile, reducing thyroid autoantibodies and body fat, and improving thyroid function...
December 1, 2023: Current Opinion in Endocrinology, Diabetes, and Obesity
https://read.qxmd.com/read/38010050/bone-mass-accrual-in-children
#19
JOURNAL ARTICLE
Eugene Rodrick, Joseph M Kindler
PURPOSE OF REVIEW: Bone accrual during childhood and adolescence is critical for the attainment of peak bone mass and is a major contributing factor towards osteoporosis in later life. Bone mass accrual is influenced by nonmodifiable factors, such as genetics, sex, race, ethnicity, and puberty, as well as modifiable factors, such as physical activity and diet. Recent progress in bone imaging has allowed clinicians and researchers to better measure the morphology, density, and strength of the growing skeleton, thereby encompassing key characteristics of peak bone strength...
November 28, 2023: Current Opinion in Endocrinology, Diabetes, and Obesity
https://read.qxmd.com/read/38010041/fibrous-dysplasia-in-children-and-its-management
#20
JOURNAL ARTICLE
Zubeyir Hasan Gun, Aleena Arif, Alison M Boyce
PURPOSE OF REVIEW: The purpose of this review is to provide a comprehensive overview into the diagnosis and management of fibrous dysplasia (FD) in children. RECENT FINDINGS: FD is a mosaic disorder arising from somatic Gαs variants, leading to impaired osteogenic cell differentiation. Fibro-osseous lesions expand during childhood and reach final disease burden in early adulthood. The mainstay of treatment focuses on surgical correction of skeletal deformities, physiatric care, and medical management of associated hyperfunctioning endocrinopathies...
November 28, 2023: Current Opinion in Endocrinology, Diabetes, and Obesity
journal
journal
41662
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.