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Journals Asian Journal of Transfusion S...

Asian Journal of Transfusion Science

https://read.qxmd.com/read/38274961/blood-components-utilization-in-hematopoietic-stem-cell-transplantation-thirteen-year-analysis-from-an-apex-oncology-center-of-india
#21
JOURNAL ARTICLE
Shashank Ojha, Vijaya Patle, P Nagaraju, Navin Khattry
BACKGROUND: Hematopoietic stem cell transplantation (HSCT) is a potentially curative treatment modality for a range of hematological disorders including malignancies. The increasing volumes of HSCTs impact transfusion services and the requirement of blood products vary depending on the primary disease, type and phase of transplant, and the HSCT donor type. MATERIALS AND METHODS: This study analyzed the factors affecting blood component requirements in patients undergoing HSCT...
2023: Asian Journal of Transfusion Science
https://read.qxmd.com/read/38274960/induction-of-thrombotic-thrombocytopenic-purpura-by-dengue-virus-infection-in-a-critical-patient-role-of-therapeutic-plasma-exchange
#22
Rathindra Nath Biswas, Sudipta Sekhar Das, Anupam Chakrapani, Subrata Sen
Thrombotic thrombocytopenic purpura (TTP) secondary to dengue fever is a very unusual occurrence. Both conditions are fatal and can result in significant mortality and morbidity if left untreated. In this case, we present a young lady who suffered dengue fever followed by microangiopathic anemia, thrombocytopenic purpura, and altered sensorium. Investigations revealed microangiopathic hemolysis; there was no evidence of disseminated intravascular coagulation. As soon as, we diagnosed the patient as having TTP, we treated her with serial plasma exchange therapy, steroids, and monoclonal antibodies such as rituximab...
2023: Asian Journal of Transfusion Science
https://read.qxmd.com/read/38274959/analytical-and-clinical-performance-evaluation-of-enhanced-chemiluminescence-based-fourth-generation-hiv-combo-assay-report-from-tertiary-health-care-setup-in-north-india
#23
JOURNAL ARTICLE
Aseem Kumar Tiwari, Geet Aggarwal, Swati Pabbi, Subhasis Mitra, Neeti Yadav, Virendra Verma, K Cheirmaraj
INTRODUCTION: HIV fourth-generation assay, designed for the detection of HIV p24 antigen along with anti-HIV antibodies of both immunoglobulin M and immunoglobulin G type against HIV 1 and HIV 2 viral antigens, have helped in the early detection of HIV infection and supports in minimizing the transmission risk in the acute phase of infection. The objective of this study was to evaluate the analytical and clinical performance of HIV fourth-generation assay based on enhanced chemiluminescence technology...
2023: Asian Journal of Transfusion Science
https://read.qxmd.com/read/38274958/implementation-of-an-international-barcode-labeling-standard-international-society-of-blood-transfusion-128-and-its-integration-with-local-regulations-at-a-blood-center-in-india-step-by-step-journey
#24
REVIEW
Geet Aggarwal, Aseem Kumar Tiwari, Swati Pabbi, Gunjan Bhardwaj, Naresh Khurana, Ganesh Rawat, Nixon P Joseph
The International Society of Blood Transfusion (ISBT) 128 is an internationally endorsed, electronically readable labeling standard that provides a convenient and accurate means of identification, traceability, publication, and storage of information for blood and blood products. The authors' center recently registered with the International Council for Commonality in Blood Banking Automation (ICCBBA) and progressed to ISBT 128 labeling standard. This manuscript was written with the objective of sharing the authors' experience with respect to the implementation of ISBT 128 standards for whole blood donations and integration of ISBT 128 standards with Indian licensing regulations...
2023: Asian Journal of Transfusion Science
https://read.qxmd.com/read/38274957/leukoreduced-red-cell-concentrates-are-they-meeting-the-quality-standards
#25
JOURNAL ARTICLE
Sreethu Chand, Raj Bharath Rudrappan, Debasish Gupta
BACKGROUND: Leukocytes are responsible for producing both immune and nonimmune adverse reactions, and therefore, various methods have been developed to remove them from the blood components before transfusion. AIM: The aim of this study was to analyze the quality parameters in leukoreduced red cell concentrates (RCCs) and investigate the efficiency of leukocyte removal and red cell recovery in the leukoreduction methods followed in our center. MATERIALS AND METHODS: The study evaluated the quality parameters in 112 RCCs prepared using buffy-coat reduction by the Terumo automatic component extractor II+ system, manual saline washing, and leukofiltration using the Leucolab filter system...
2023: Asian Journal of Transfusion Science
https://read.qxmd.com/read/38274956/serial-analysis-of-hematological-biochemical-and-immunological-parameters-alterations-in-regular-healthy-voluntary-donors-during-plateletpheresis-donation
#26
JOURNAL ARTICLE
Rekha Hans, Deepak Pahwa, Preeti Paul, Jyotdeep Kaur, Biman Saikia, Ratti Ram Sharma, Neelam Marwaha
BACKGROUND AND OBJECTIVES: The long-term effect of regular plateletpheresis on donors has not been characterized. Hence, we planned to study the long-term alterations in hematological, biochemical, and immunological parameters in regular repeat platelet apheresis donors. MATERIALS AND METHODS: Thirty-three healthy voluntary regular repeat apheresis donors presenting for platelet donation, fulfilling the requisite donor selection criteria, underwent sequential analysis of the hematological, biochemical, and immunological parameters over 1 year...
2023: Asian Journal of Transfusion Science
https://read.qxmd.com/read/38274955/determination-of-the-rh-kell-phenotypes-in-donor-as-well-as-patients-might-be-significant-to-provide-phenotype-matched-blood-to-cancer-patients-a-retrospective-analysis-from-a-tertiary-care-oncology-center-in-north-india
#27
JOURNAL ARTICLE
Amardeep Pathak, Narender Tejwani, Devasis Panda, Anurag Mehta
BACKGROUND: Multiple reports are available from different parts of the globe indicating the incidences of alloimmunization and blood transfusion-related reactions, which emphasizes the need for phenotyping and providing antigen-matched safe blood. AIMS AND OBJECTIVES: This study aims to determine the frequency of Rh and Kell antigens and phenotype for both donors and patients to propose the importance of providing Rh Kell phenotype cross-matched packed red blood cell (RBC) units to minimize the alloimmunization and transfusion reactions...
2023: Asian Journal of Transfusion Science
https://read.qxmd.com/read/38274954/white-thrombus-fibrin-in-the-blood-bag
#28
JOURNAL ARTICLE
John Gnanaraj, Naadia Nadeem, Esha Toora, Debdatta Basu, Abhishekh Basavarajegowda
No abstract text is available yet for this article.
2023: Asian Journal of Transfusion Science
https://read.qxmd.com/read/38274953/prevalence-of-gp-mur-variant-phenotype-among-malaysian-blood-donors
#29
JOURNAL ARTICLE
Siti Nazihahasma Hassan, Suharni Mohamad, Thirumulu Ponnuraj Kannan, Rosline Hassan, ShuangShi Wei, Wan Suriana Wan Ab Rahman
BACKGROUND AND OBJECTIVE: A number of glycophorin variant phenotypes or hybrid glycophorin variants of the MNS blood group system bear multiple immunogenic antigens such as Mia , Mur, and MUT. In the East and Southeast Asian populations, glycoprotein (GP.) Mur is the most common glycophorin variant phenotype expressing those three immunogens. The aim of this study was to detect MNS system glycophorin variant phenotypes (GP. Mur, GP. Hop, GP. Bun, GP. HF, and GP. Hut) among Malaysian blood donors...
2023: Asian Journal of Transfusion Science
https://read.qxmd.com/read/38274952/experience-from-an-immunohematology-reference-testing-center
#30
JOURNAL ARTICLE
Ankit Mathur, Nippun Prinja, A Srivalli, Santanu Chakraboty, T S Vijay Kumar Reddy
Blood Centres in India lack infrastructure to investigate immunohematology problems. Reference Testing Center (RTC) was established in 2014 to investigate Immunohematological problem as it is not possible for small blood centers to go for complete immunohematology work up due to lack of financial and technical resources in remote and rural areas. Objective of this study is to share our experience as RTC of past 6 years so that more RTC are established across Indian subcontinent. 1456 Discrepant samples received from various hospitals of South India for Immunohematology problems were analysed in 6 years...
2023: Asian Journal of Transfusion Science
https://read.qxmd.com/read/38274951/redefining-the-role-of-therapeutic-plasma-exchange-in-complications-of-echis-carinatus-sochureki-envenomation-refractory-to-anti-snake-venom-a-case-series
#31
Davood Bava, P H Akhilesh Kumar, Anubhav Gupta, Saptarshi Mandal, Archana Bajpayee, Maya Gopalakrishnan, Md Atik Khan
INTRODUCTION: Saw-scaled viper ( Echis carinatus ) belongs to the Viperidae family. Its venom is hemotoxic and contains several small peptides and proteins affecting the coagulation system. Commonly used anti-snake venom (ASV) products in India are reported to be ineffective or less effective in cases with bites by Echis carinatus sochureki which are commonly found in desert areas in Rajasthan. Although therapeutic plasma exchange (TPE) has been successful in patients with snakebite envenomation in the past, American Society for Apheresis guidelines 2019 included this indication under category III with grade 2C recommendation...
2023: Asian Journal of Transfusion Science
https://read.qxmd.com/read/38274950/hemolysin-test-as-a-tool-to-screen-high-titer-group-o-platelet-apheresis-donors-a-prospective-study
#32
JOURNAL ARTICLE
Mohandoss Murugesan, Merline Augustine, Shibin Cherukunnuparambil Velayudhan, Thahira Darussalam, Sangeetha Keloth Nayanar
BACKGROUND: Minor ABO-incompatible apheresis platelet transfusion poses a risk of hemolytic transfusion reactions in non-Group O recipients when donor's plasma possesses unusual high titers for anti-A and anti-B. The aim was to determine whether the hemolysin test can be used as a screening tool to predict high-titer Group O platelet apheresis donors. METHODS: A prospective study, with Group O platelet donor's samples, was tested for hemolysin test and antibody titration test in parallel...
2023: Asian Journal of Transfusion Science
https://read.qxmd.com/read/37188035/transfusion-reactions-in-neonates-and-pediatrics-how-and-why-are-they-different
#33
REVIEW
Abhishekh Basavarajegowda, Nishad Plakkal
Neonates and children are physically as well as physiologically different from adults. They are immunologically vulnerable, and the effects of transfusion can be longstanding, including with respect to their development. The transfusion reactions in children differ from those in adults in the type of reactions, incidence, and severity. The incidence is more than that in adults for the common type of reactions noted in children. Transfusion reactions are most commonly associated with platelets, followed by plasma and red blood cell transfusions in children...
2023: Asian Journal of Transfusion Science
https://read.qxmd.com/read/37188034/a-case-report-on-para-bombay-blood-group
#34
A G Krishnaveni, S Vasanth
Rare blood group detection is important as the incidence of these blood groups is very low. These rare blood groups need a transfusion of blood from the same group of people; sometimes, it is not available in blood banks. It is important to detect them in the field of transfusion medicine so that the right transfusion at the right time and for the right patient is ensured. We had one patient who was identified as blood group O in a private laboratory and the patient came to our hospital for anemia during the second trimester of pregnancy whose forward grouping showed no agglutination in the anti-a and anti-b and also no agglutination in the anti-H so we thought it to be Bombay blood group...
2023: Asian Journal of Transfusion Science
https://read.qxmd.com/read/37188033/autoantibodies-mimicking-alloantibodies-a-case-series-unveiling-the-dilemmas-of-transfusion
#35
JOURNAL ARTICLE
Soma Agrawal, Mohit Chowdhry, Shiva Prasad Gajullupalli, Muthukumaravel
INTRODUCTION: Autoimmune hemolytic anemia is characterized by increased red cell destruction and/or decreased red cell survival due to autoantibodies directed against self-antigens on red cells. Since autoantibodies react with self and nonself red blood cells (RBCs), they tend to mask the underlying clinically significant alloantibodies and many a times mimic a specific pattern like alloantibodies. MATERIALS AND METHODS: We discuss three immune hematological cases of warm autoantibodies...
2023: Asian Journal of Transfusion Science
https://read.qxmd.com/read/37188032/role-of-therapeutic-plasma-exchange-in-rat-killer-yellow-phosphorous-poisoning
#36
JOURNAL ARTICLE
Krishnamoorthy Radhakrishnan, Ravindra Prasad Thokala, Ashwin Anandan, Chandran Srinivasan Rengan
CONTEXT: Yellow phosphorus (YP) 3% is one of the rodenticides available, which is a potent hepatotoxin and it is fatal. Management of YP poisoning is difficult since there is no antidote available; only definitive management is liver transplantation. Therapeutic plasma exchange (TPE) helps the YP poisoning patients by removing the poison or its metabolite or the inflammatory mediators released in the body in response to toxin. AIMS: To determine the role of TPE in rat killer (YP) poisoning...
2023: Asian Journal of Transfusion Science
https://read.qxmd.com/read/37188031/a-comparison-of-serological-phenotyping-and-molecular-genotyping-for-kell-kidd-and-duffy-antigens-in-multi-transfused-thalassemia-patients
#37
JOURNAL ARTICLE
Atul Sonker, Anju Dubey, Yatendra Mohan
BACKGROUND: In multi-transfused thalassemia patients, serological phenotyping fails to test patient's actual blood group antigen profile due to the presence of donor red blood cell (RBC) in the circulation. This limitation of serological tests can be overcome by genotype determination using the polymerase chain reaction (PCR)-based methods. The aim of this study is to compare the serological phenotyping of Kell, Kidd, and Duffy blood group systems with molecular genotyping in the normal blood donors and multi-transfused thalassaemia patients...
2023: Asian Journal of Transfusion Science
https://read.qxmd.com/read/37188030/patient-outcome-in-antibody-positive-systemic-vasculitis-treated-with-therapeutic-plasma-exchange
#38
JOURNAL ARTICLE
Aseem Kumar Tiwari, Divya Setya, Dhaval Tanna, Dinesh Arora, Geet Aggarwal, Rajiva Gupta, Shyam Bihari Bansal, Sidharth Kumar Sethi
BACKGROUND: Therapeutic plasma exchange (TPE) has been advocated as an adjunct to steroids and cytotoxic drugs in treating patients suffering from vasculitis and presenting with active disease, but we still have insufficient evidence on its effectiveness in improving the clinical response, especially in India. This study was planned to study the clinical outcome in severe vasculitic presentations treated with TPE as an adjunctive therapy. MATERIALS AND METHODS: A retrospective analysis of TPE procedures performed from July 2013 to July 2017 in the department of transfusion medicine at a large tertiary care hospital was done...
2023: Asian Journal of Transfusion Science
https://read.qxmd.com/read/37188029/a-prospective-observational-study-to-evaluate-effect-of-heat-inactivation-on-abo-titers-performed-by-column-agglutination-technology-and-conventional-tube-technique
#39
JOURNAL ARTICLE
Prashant Pandey, Divya Setya, Shweta Ranjan, Mukesh Kumar Singh
BACKGROUND AND AIMS: When determining ABO antibody titers, immunoglobulin G (IgG) antibodies can be masked by immunoglobulin M (IgM) antibodies. Hence, the measurement of actual concentration of IgG requires methods like heat inactivation (HI) of plasma. This study was aimed at determining the effects of HI on IgM and IgG titers performed by conventional tube technique (CTT) and column agglutination technique (CAT). MATERIALS AND METHODS: This was a prospective, observational study conducted from October 2019 to March 2020...
2023: Asian Journal of Transfusion Science
https://read.qxmd.com/read/37188028/comparative-study-between-chronic-automated-red-blood-cell-exchange-and-manual-exchange-transfusion-in-patients-with-sickle-cell-disease-a-single-center-experience-from-saudi-arabia
#40
JOURNAL ARTICLE
Nour Al Mozain, Yasmin Elobied, Amal Al-Omran, Alhanouf Aljaloud, Alanoud Bin Omair, Reema Bin Tuwaim, Sara Alkhalifah, Esraa S Altawil, Sheena Abraham, Lejardine Rose Salcedo, Aljoyce Parena, Farrukh Shah, M Tayyeb Ayyoubi, Daniela Hermelin, Farjah Al Gahtani, Mervat Abdalhameed Alfeky, Ghada El Gohary
BACKGROUND: Red cell transfusion remains the gold standard in managing sickle cell disease (SCD) with severe complications. Offering red blood cell exchange (RBCX) either manual exchange transfusion (MET) or automated RBCX (aRBCX) can reduce the complications of chronic transfusion and maintain target Hb thresholds. This study audits the hospital experience of overseeing adult SCD patients treated with RBCX, both automated and manual, and compares the safety and efficacy. MATERIALS AND METHODS: This retrospective observational study was conducted as an audit for chronic RBCX for adult patients with SCD in 2015-2019 at King Saud University Medical City, Riyadh, Saudi Arabia...
2023: Asian Journal of Transfusion Science
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