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LETTER
Edwin S Wong, Karen M Stechuchak, Valerie A Smith, Anna Hung, Paul A Dennis, Katherine D Hoerster, Matthew L Maciejewski
The prevalence of overweight and obesity among military personnel has increased substantially in the past two decades. Following military discharge many personnel can receive integrated health care from the Veterans Health Administration. Prior research related to the economic impacts of obesity has not examined health care costs following the transition into civilian life following military discharge. To address this evidence gap, this study sought to compare longitudinal costs over 10 years across weight categories among VA enrollees recently discharged from the military...
April 1, 2024: Obesity Research & Clinical Practice
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JOURNAL ARTICLE
Kenji Kaneko, Ryunosuke Mitsuno, Daiki Kojima, Tatsuhiko Azegami, Shotaro Kosugi, Toshifumi Nakamura, Akinori Hashiguchi, Yoshitake Yamada, Masahiro Jinzaki, Shintaro Yamaguchi, Hiroshi Itoh, Jun Yoshino, Kaori Hayashi
OBJECTIVE: Obesity is a risk factor of chronic kidney disease (CKD), contributing to the rising incidence of cardiometabolic diseases. Renal sinus fat (RSF) is an ectopic fat depot located at the renal cavity that could impair renal function and hemodynamic through compression of renal structures. The major purpose of this study was to explore the relationship between RSF accumulation and renal dysfunction in CKD patients. METHODS: We evaluated the associations between computed tomography measured RSF volume and key clinical and histologic parameters involved in renal function and hemodynamics in 132 well-characterized CKD patients who underwent renal biopsy (median age: 62 years; 63...
March 29, 2024: Obesity Research & Clinical Practice
#23
JOURNAL ARTICLE
Abubakr Ahmed Abdullah Al-Shoaibi, Yuanying Li, Zean Song, Young Jae Hong, Chifa Chiang, Yoshihisa Nakano, Yoshihisa Hirakawa, Masaaki Matsunaga, Atsuhiko Ota, Koji Tamakoshi, Hiroshi Yatsuya
BACKGROUND: The association between obesity and cardiovascular disease (CVD) remains unclear, particularly for those with established CVD risk factors. We analyzed follow-up data from the Aichi Workers' Cohort Study. We studied the association between the degree of obesity and risk of CVD and its subtypes specifically among individuals with hypertension, hyper-low-density lipoprotein (LDL)-cholesterolemia, or diabetes. METHODS: Pooled data of 8972 adults (7076 men and 1896 women) who were recruited between 2002 and 2008 were used in the current analysis...
March 12, 2024: Obesity Research & Clinical Practice
#24
JOURNAL ARTICLE
Tiantian Cheng, Jingjing Fan, Fang Yuan, Huanhuan Xie, Cuilian Zhang, Qiaohua He
OBJECTIVE: To investigate the association between pre-pregnancy body mass index (BMI) and the early pregnancy loss rate in patients in first hormone replacement therapy-frozen-thawed embryo transfer (HRT-FET) cycles and find the threshold. METHODS: A retrospective cohort study was conducted using a total of 14030 HRT-FET cycles at the Reproductive Center from January 2017 to December 2021. The association of pre-pregnancy BMI on early pregnancy loss rate in patients in HRT-FET cycles was assessed by performing univariate analysis, multivariable logistic regression, curve fitting and threshold effect analysis...
March 6, 2024: Obesity Research & Clinical Practice
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JOURNAL ARTICLE
Diana Rodrigues-Martins, Tiago Esteves, Sara Andrade, Jorge Braga, Inês Nunes, Mariana P Monteiro
INTRODUCTION: Metabolic and bariatric surgery (MBS) is a very effective weight loss intervention, although does not invariably reverses the obesity status. Our aim was to evaluate whether despite successful weight loss after MBS, persistence of obesity at time of conception still carries additional risks of adverse perinatal pregnancy outcomes. METHODS: Retrospective study comparing pregnancy outcomes of women previously submitted to MBS with a preconception (PC) body mass index BMI < 30 kg/m2 or PC BMI ≥ 30 kg/m2 ...
February 23, 2024: Obesity Research & Clinical Practice
#26
LETTER
Jared A Houssarini, Janet Franklin, Tania Markovic, Samantha L Hocking
No abstract text is available yet for this article.
February 15, 2024: Obesity Research & Clinical Practice
#27
REVIEW
Jiyun Ahn, Caroline Simpkins, Feng Yang
This review sought to meta-analyze previous research observing the effects of fat mass distribution on the fall risk among people with obesity. The literature search yielded five qualified studies enrolling 1218 participants (650 with android vs. 568 with gynoid). The outcome variables included the annual fall prevalence (primary outcome) and the center of pressure (COP) movement measurements during a posturography test (secondary) among people with android or gynoid obesity. Meta-analyses were conducted using the inverse variance weighted random-effects model...
February 14, 2024: Obesity Research & Clinical Practice
#28
LETTER
Nick S R Lan, Umar S Ali, Robert Larbalestier, Girish Dwivedi, P Gerry Fegan
Patients undergoing coronary artery bypass graft (CABG) surgery require intensive secondary prevention. Semaglutide reduced cardiovascular events in patients with cardiovascular disease and overweight or obesity but without diabetes in the SELECT trial. In this real-world study of 1386 patients without diabetes undergoing CABG surgery in an Australian hospital, approximately 1 in 2 patients (53.3 %) were potentially eligible for semaglutide based on the SELECT trial criteria. These findings highlight that a significant percentage of this very high-risk cohort merit receiving semaglutide for weight management and cardiovascular risk reduction...
February 7, 2024: Obesity Research & Clinical Practice
#29
JOURNAL ARTICLE
Tsung Yu, Tzu-Jung Wong, Jen-Wen Chang, Xiang-Qian Lao
BACKGROUND: Although the prevalence of overweight/obesity is lower in Asian countries, the risk of type 2 diabetes (T2DM) is disproportionally higher. We identified and characterized the trajectory patterns of body mass index (BMI) before the onset of T2DM in a Taiwanese population. METHODS: Using the Taiwan MJ cohort study, we sampled the health examination data of 22,934 participants, including 7618 cases of T2DM and 15,316 controls. We used latent class trajectory analysis to identify distinct groups of pre-disease BMI trajectory...
February 7, 2024: Obesity Research & Clinical Practice
#30
JOURNAL ARTICLE
Wandia Kimita, Loren Skudder-Hill, Xiatiguli Shamaitijiang, Sunitha Priya, Maxim S Petrov
OBJECTIVE: To comprehensively investigate the associations of pancreas fat content and size with circulating markers of iron metabolism. METHODS: A total of 116 individuals underwent magnetic resonance imaging and spectroscopy on a 3.0 Tesla scanner, exclusively for the purpose of the COSMOS research programme. Intra-pancreatic fat deposition, total pancreas volume, liver fat content, visceral and subcutaneous fat volumes were quantified. Plasma levels of hepcidin and ferritin were measured...
January 25, 2024: Obesity Research & Clinical Practice
#31
LETTER
Priscila Berti Zanella
No abstract text is available yet for this article.
January 19, 2024: Obesity Research & Clinical Practice
#32
JOURNAL ARTICLE
Minoo Heidari Almasi, Maryam Barzin, Maryam Mahdavi, Alireza Khalaj, Majid Valizadeh, Farhad Hosseinpanah
BACKGROUND: Considering the lack of a standardized definition for weight recurrence (WR), the prevalence and predictors of WR remain inconsistent. METHODS: The prospective study was conducted on 1939 individuals who underwent bariatric surgery;66.8% underwent sleeve gastrectomy (SG), 33.2%, underwent gastric bypass (GB)[of them 87% one-anastomosis gastric bypass (OAGB), and 13% Rue and Y gastric bypass (RYGB)]. During a follow-up of 72 months, the prevalence of WR ranged from 13...
January 16, 2024: Obesity Research & Clinical Practice
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JOURNAL ARTICLE
Shabbar Jamaly, Christina E Lundberg, Martin Adiels, Jesper Lagergren, Lena Björck, Annika Rosengren
AIMS: To assess the long-term risk of developing type 2 diabetes in patients with obesity who have undergone gastric bypass surgery compared to non-operated patients with obesity and the general population. METHODS: This study included 71,495 patients aged 20-65 years with a principal diagnosis of obesity in the Swedish Patient Register in 2001-2013. Of these, 23,099 had undergone gastric bypass and 32,435 had not. Each patient was matched by age, sex and geographic region with two controls from the general population without obesity diagnosis, i...
January 9, 2024: Obesity Research & Clinical Practice
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JOURNAL ARTICLE
Shiri Sherf-Dagan, Lani Ofri, Inbar Tayar, Ido Keisar, Assaf Buch, Naama Paska-Davis, Michael Pinus, Riki Tesler, Roni Elran-Barak, Mona Boaz, Gizell Green
BACKGROUND: Weight bias toward people with obesity (PwO) is common in healthcare settings. Efforts to address weight bias in healthcare settings should begin during university studies. This study aimed to explore the effect of a multifaceted intervention on weight bias among undergraduate healthcare students. METHODS: An open label randomized controlled trial. The intervention tool consisted of short video lectures on obesity, vignettes simulating interactions between health professionals and PwO, and open discourse with a PwO...
January 5, 2024: Obesity Research & Clinical Practice
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JOURNAL ARTICLE
I V Frielitz-Wagner, J Mattutat, F S Frielitz, K Scheuermann, J Gesing, D Marheineke, D Löffler, W Kiess, A Körner
RESEARCH AIM: Nicotinamide phosphoribosyltransferase (Nampt) is an adipocytokine that is elevated in obesity, type 2 diabetes and increased levels are associated with inflammatory processes. Nampt serum concentrations have been suggested to follow a diurnal rhythm peaking in the afternoon in lean males. However, no data exists regarding the effects of gender and body weight. MATERIAL AND METHODS: We measured Nampt serum levels over 24 h in a cohort of healthy individuals living with either normal weight or obesity...
2024: Obesity Research & Clinical Practice
#36
RANDOMIZED CONTROLLED TRIAL
Camilla M Hoyos, Elizabeth A Machan, Brendon J Yee, Svetlana Postnova, Nathaniel S Marshall, Tania Markovic, Stephen M Twigg, Ronald R Grunstein, Craig L Phillips
BACKGROUND AND AIMS: This study assessed whether the addition of continuous positive airway pressure (CPAP) during weight loss would enhance cardiometabolic health improvements in patients with obesity and Obstructive Sleep Apnoea (OSA). METHODS AND RESULTS: Patients with overweight or obesity, pre-diabetes and moderatesevere OSA were randomised to receive CPAP therapy with a weight loss programme (CPAP+WL) or a weight loss programme alone (WL alone). PRIMARY OUTCOME: 2-hour glucose assessed by an oral glucose tolerance test...
2024: Obesity Research & Clinical Practice
#37
MULTICENTER STUDY
Amrit Manik Nasta, Ramen Goel, Rishi Singhal, Luc Lemmens, Sarfaraz Baig, Yosuke Seki, Arun Prasad, Sonja Chiappetta, Mohammad Kermansaravi, Marc Vertruyen, Beniamino Pascotto, Juan Santiago Azagra, Waleed Al-Khyatt, Gennaro Martines, Diva Y Villao, Leandro Revello, Marco Rioseco, Francesco Martini, Arnaud Liagre, Gildas Juglard, Giovanni Dapri, Monika A Proczko-Stepaniak, Adel K Abou-Mrad, Hosam M Elghadban, Christine Stier, Jasper L E Van Herck, Safwan Abdulrahman Taha, Ozan Şen, Bruno Dillemans, Stijn Van Hoef, Mathieu Vandeputte, Sofie Viskens, Paolo Gentileschi, Raj Palaniappan, Nasser Sakran, Thomas H Shin, Ali Aminian, Matteo Uccelli, Stefano Olmi, Giovanni C Cesana, Marco Anselmino, Nicolas P A Debergh, Daniel Gärtner, Wah Yang, Digvijay S Bedi, Kamal Mahawar
INTRODUCTION: Revisional bariatric surgery (RBS) for insufficient weight loss/weight regain or metabolic relapse is increasing worldwide. There is currently no large multinational, prospective data on 30-day morbidity and mortality of RBS. In this study, we aimed to evaluate the 30-day morbidity and mortality of RBS at participating centres. METHODS: An international steering group was formed to oversee the study. The steering group members invited bariatric surgeons worldwide to participate in this study...
2024: Obesity Research & Clinical Practice
#38
REVIEW
Sergi Sanchez-Cordero, Ruth Lopez-Gonzalez, Jordi Pujol-Gebellí, Jordi Castellvi-Valls
Transit bipartition (TB) emerges as a bariatric surgery alternative to Duodenal Switch (DS), emphasizing complete intestinal access and reduced malabsorption. By directly stimulating the distal ileum, TB promotes weight loss while preserving endoscopic duodenal access. This technique enhances anorexigenic hormones, aiding in satiety and weight loss, with lower malnutrition risks than DS. TB shows favorable short-term outcomes in weight management and comorbidity reduction, serving as a simpler, less malabsorptive option than DS...
2024: Obesity Research & Clinical Practice
#39
JOURNAL ARTICLE
Emma Farrell, Carel W le Roux, Eva Hollmann, Joseph Nadglowski, Deirdre McGillicuddy
OBJECTIVE: Personalised medicine is seen as an exciting opportunity to improve the health outcomes of people with obesity. As research on phenotyping and personalised treatment for obesity rapidly advances, this study sought to understand patient preferences and perspectives on personalised medicine for obesity. METHODS: A participatory world café methodology was used to garner the perspectives of people living with obesity on the potential opportunities and limitations associated with a personalised approach to obesity risk identification and treatment...
2024: Obesity Research & Clinical Practice
#40
JOURNAL ARTICLE
Nicole A Cho, Gerald F Giesbrecht, Deborah Dewey, Raylene A Reimer
Early life antibiotic exposure may increase obesity risk. We investigated if prenatal, intrapartum, or childhood antibiotic use is associated with child zBMI score at 4 yrs of age. We included data from the Alberta Pregnancy Outcomes and Nutrition (APrON) study, a prospective cohort study, on maternal and child antibiotic exposure and clinic measures of height and weight at age 4 (n = 408). Prenatal and childhood antibiotic exposure was not associated with zBMI score. Maternal intrapartum antibiotic exposure was associated with a zBMI score increase of 0...
2024: Obesity Research & Clinical Practice
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