Antoine Baudriller, Chadi Abbara, Marie Briet, Séverine Ferec, Léa-Héléna Rossi, Nathalie Jousset, Stéphane Malbranque, Guillaume Drevin
Analysis and interpretation of the findings for γ-hydroxybutyrate (GHB) in related fatalities remains problematic. Indeed, GHB is a naturally occurring compound present in both the mammalian central nervous system and peripheral tissue. Moreover, a postmortem increase in endogenous GHB concentration has been observed, especially in blood. Facing this issue, the use of an alternative matrix such as vitreous humor (VH) can thus be particularly interesting for GHB testing and quantification. VH is considered to be less prone to postmortem redistribution, is easy to collect, and has relatively few interfering compounds for the analytical process...
January 4, 2024: Journal of Forensic and Legal Medicine