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Journals Arab Journal of Gastroenterolo...

Arab Journal of Gastroenterology : the Official Publication of the Pan-Arab Association of Gastroenterology

https://read.qxmd.com/read/38514367/brucellosis-in-a-patient-with-crohn-s-disease-treated-with-infliximab-a-case-report
#1
JOURNAL ARTICLE
Mansour Altuwaijri, Nasser Alkhraiji, Mosaab Almasry, Saad Alkhowaiter, Nuha Al Amaar, Ammar Alotaibi
Crohn's disease (CD) is an inflammatory disease that can affect any part of the gastrointestinal tract and presents with myriad symptoms. Various treatments, including biological treatments, are available. The use of biologics increases the risk of opportunistic infections, with no association with serious infections (1). To the best of our knowledge, there are no established recommendations or case studies for patients with CD infected with Brucella being actively treated with biologics and immunomodulators to date...
March 21, 2024: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
https://read.qxmd.com/read/38458876/association-of-low-serum-25-hydroxy-vitamin-d-25-oh-d-with-hepatic-encephalopathy-in-patients-with-decompensated-liver-cirrhosis
#2
JOURNAL ARTICLE
Abdul Mumit Sarkar, Abdullah Al Mukit, Tanzilul Bari, Rofiqul Islam, Shafiqul Islam, Khalequzzaman Sarker, Manzurul Chowdhury, Mohd Harun Or Rashid, Abdul Alim
BACKGROUND AND STUDY AIMS: The mechanism of hepatic encephalopathy is complex and has not been conclusively established. Recent studies support lower serum 25-Hydroxy Vitamin D [25(OH) D] levels in patients with hepatic encephalopathy. This study aimed to evaluate the association between serum 25(OH) D and hepatic encephalopathy in patients with decompensated cirrhosis of liver. PATIENTS AND METHODS: A total of 70 cirrhosis patients (35 cases of hepatic encephalopathy and 35 patients without encephalopathy as control, mean age 53...
March 8, 2024: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
https://read.qxmd.com/read/38423856/treatment-with-antituberculosis-agents-after-tuberculosis-activation-during-ustekinumab-treatment-safety-and-effectiveness
#3
Zhizhi Wang, Wangdi Liao, Youxiang Chen, Shunhua Long
We report, for the first time, the safety and effectiveness of antituberculosis drugs after tuberculosis activation during ustekinumab treatment in Crohn's disease.
February 28, 2024: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
https://read.qxmd.com/read/38418285/the-impact-of-endocuff-assisted-colonoscopy-on-the-polyp-detection-rate-a-cross-over-randomized-back-to-back-study
#4
JOURNAL ARTICLE
Mohammed Sherif Naguib, Ahmed Khairy, Hany Shehab, Hazem Abosheaishaa, Abdel Meguid Kassem
BACKGROUND AND STUDY AIMS: Colorectal cancer (CRC) is one of the most common cancers worldwide, and most CRCs develop from polyps with malignant potential. We aimed to study the difference in polyp detection rate between EndoCuff-assisted colonoscopies (EAC) and standard colonoscopy (SC). PATIENTS AND METHODS: This study was conducted at Cairo University Hospitals on patients referred for screening or diagnostic colonoscopy from July 2018 to August 2020. All included patients underwent back-to-back standard colonoscopy (SC) and ENDOCUFF VISION-assisted colonoscopies (EAC)...
February 27, 2024: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
https://read.qxmd.com/read/38413325/differences-in-circulating-lymphocyte-subpopulations-among-patients-with-inflammatory-polyps-colorectal-adenomas-and-colorectal-cancer
#5
JOURNAL ARTICLE
Jialai Zheng, Haiyong Jin, Yongtao Tu
BACKGROUND AND STUDY AIMS: Colorectal cancer (CRC) may develop from focal changes within benign or precancerous polyps. The immune system's failure to detect and eradicate tumor cells due to immune surveillance evasion, allows cancer to develop and spread. This study aims to analyze the differences in circulating lymphocyte subpopulations in patients with colorectal inflammatory polyps, colorectal adenomas and CRC. PATIENTS AND METHODS: We retrospectively reviewed patients from September 2016 to December 2019 at the Shaoxing Second Hospital...
February 26, 2024: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
https://read.qxmd.com/read/38413324/multidrug-resistance-gene-1-polymorphisms-c3435t-and-g2677t-and-the-risk-of-inflammatory-bowel-disease-in-egyptian-patients
#6
JOURNAL ARTICLE
Raghda Marzaban, Rania Mohamed Samy, Mona Ahmed Kassem, Mira Atef
BACKGROUND AND STUDY AIMS: The multidrug resistance 1 (MDR1) gene is a gene involved in the pathogenesis of inflammatory bowel disease (IBD).The aim of the study is to investigate the association of MDR-1 gene polymorphisms (C2345T and G2677T) and IBD incidence in Egyptian patients, and its relation with disease severity. PATIENTS AND METHODS: This is a case-control study where genotyping of MDR-1 gene C3435T and G2677T single nucleotide polymorphisms (SNPs) were assayed...
February 26, 2024: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
https://read.qxmd.com/read/38403495/effect-of-lidocaine-on-postoperative-analgesia-of-endoscopic-rubber-band-ligation-combined-with-injection-sclerotherapy-for-treatment-of-internal-hemorrhoids-a-retrospective-study-with-video
#7
JOURNAL ARTICLE
Wen Xu, Guili Xia, Ling Dong, Ying Zhu
BACKGROUND AND STUDY AIMS: Endoscopic minimally invasive treatment of internal hemorrhoids may cause postoperative pain. The aim of the study is to investigate the analgesic effect of lidocaine plus lauromacrogol on postoperative pain caused by endoscopic rubber band ligation (ERBL) combined with injection sclerotherapy (IS) for internal hemorrhoids treatment. PATIENTS AND METHODS: Clinical data of grade Ⅲ internal hemorrhoids patients who underwent ERBL combined with IS in department of Digestive Medicine, Shenzhen Hospital of Southern Medical University, were retrospectively analyzed...
February 24, 2024: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
https://read.qxmd.com/read/38403494/sonographic-features-of-lemmel-s-syndrome-differential-diagnosis-from-stones-in-the-lower-portion-of-the-common-bile-duct
#8
JOURNAL ARTICLE
Jinxiu Ju, Yating Su, Qingjing Zeng, Jiayi Liang, Xiaodan Zhang, Jie Ren, Lili Wu, Rongqin Zheng
BACKGROUND AND STUDY AIMS: Periampullary diverticula (PAD), a location-specific type of duodenal diverticula, can cause serious complications. PAD is difficult to differentially diagnose, mainly due to its nonspecific symptoms. This study aimed to identify sonographic features of PAD and to evaluate their value in the differential diagnosis of PAD from stones in the lower common bile duct (CBD). PATIENTS AND METHODS: A total of 30 patients with PAD and 60 patients with lower CBD stones were retrospectively enrolled, and sonographic features were analyzed...
February 24, 2024: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
https://read.qxmd.com/read/38403493/efficacy-of-l-ornithine-l-aspartate-for-minimal-hepatic-encephalopathy-in-patients-with-cirrhosis-a-meta-analysis-of-randomized-controlled-trials
#9
REVIEW
Qiufeng He, Chuangjie Mao, Zhili Chen, Yilan Zeng, Yang Deng, Rong Hu
BACKGROUND AND STUDY AIMS: Minimal hepatic encephalopathy (MHE) is an early stage of hepatic encephalopathy (HE) and is highly prevalent. The efficacy of L-ornithine L-aspartate (LOLA) for the treatment of HE is well known but its role in MHE remains uncertain. The objectives of the current study were to evaluate the efficacy of LOLA for the treatment of MHE in patients with cirrhosis. METHODS: The Cochrane Library, PubMed, EMBASE, Web of Science and Ovid databases were searched...
February 24, 2024: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
https://read.qxmd.com/read/38395629/the-role-of-il-19-il-24-il-21-and-il-33-in-intestinal-mucosa-of-inflammatory-bowel-disease-a-narrative-review
#10
REVIEW
Alexandros Toskas, Stefanos Milias, Theodora Papamitsou, Soultana Meditskou, Nikolaos Kamperidis, Antonia Sioga
Interleukins are potential therapeutic targets that can alter the prognosis and progression of inflammatory bowel disease (IBD). The roles of IL-6, IL-10, IL-17, and IL-23 have been extensively studied, setting the stage for the development of novel treatments for patients with IBD. Other cytokines have been less extensively studied. Members of the IL-20 family, mainly IL-19 and IL-24, are involved in the pathogenesis of IBD, but their exact role remains unclear. Similarly, IL-33, a newly identified cytokine, has been shown to control the Th1 effector response and the action of colonic Tregs in animal models of colitis and patients with IBD...
February 23, 2024: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
https://read.qxmd.com/read/38388217/risk-factors-of-liver-abscess-and-biloma-formation-after-drug-eluting-bead-transarterial-chemoembolization-for-unresectable-intrahepatic-cholangiocarcinoma
#11
JOURNAL ARTICLE
Longhao Bian, Jianjun Yang, Zhaomin Song
BACKGROUND AND STUDY AIMS: Drug-eluting bead transarterial chemoembolization (DEB-TACE) causes serious complications, including liver abscess and biloma formation. This study aimed to investigate the frequency and risk factors of liver abscess and biloma formation after dug-eluting bead transarterial chemoembolization for unresectable intrahepatic cholangiocarcinoma (ICC). PATIENTS AND METHODS: 152 unresectable ICC patients received 241 DEB-TACE procedures from February 2018 to November 2022 were studied retrospectively...
February 21, 2024: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
https://read.qxmd.com/read/38383265/risk-of-tuberculosis-with-anti-tnf-therapy-in-indian-patients-with-inflammatory-bowel-disease-despite-negative-screening
#12
JOURNAL ARTICLE
Suprabhat Giri, Sukanya Bhrugumalla, Akash Shukla, Sagar Gangadhar, Srujan Reddy, Sumaswi Angadi, Leela Shinde, Aditya Kale
BACKGROUND AND STUDY AIMS: Tuberculosis (TB) is a well-recognized adverse effect associated with using biological therapy to manage various autoimmune conditions. There is a dearth of information about the development of TB after using anti-TNF agents in patients with inflammatory bowel disease (IBD) from TB-endemic countries like India. This study aimed to estimate the risk of TB and its predictors after treatment with anti-TNF agents in patients with IBD. PATIENTS AND METHODS: The present study is a retrospective analysis of data of patients with IBD from two tertiary care centers in India receiving anti-TNF therapy...
February 21, 2024: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
https://read.qxmd.com/read/38383264/acyl-ghrelin-desacyl-ghrelin-and-their-ratio-affect-hepatic-steatosis-via-ppar%C3%AE-signaling-pathway
#13
JOURNAL ARTICLE
Emine Elibol, Yasemin Akdevelioğlu, Canan Yılmaz, Belkıs Narlı, Serkan Şen, Gülnur Take Kaplanoğlu, Cemile Merve Seymen
BACKGROUND AND STUDY AIMS: Ghrelin is an appetite hormone-containing 28-amino acid and has 4 different forms in the body. Ghrelin forms have different physiological functions in the body. This study aims to analyze the effect of acyl and desacyl ghrelin hormone on hepatic steatosis and biochemical findings in 36 male Wistar rats. MATERIALS AND METHODS: Rats were split into 6 equal groups, consisting of control, acyl ghrelin, desacyl ghrelin, acyl/desacyl 3:1, acyl/desacyl 1:1, and acyl/desacyl 1:3 groups, and administered placebo or 200 ng/kg hormone subcutaneous twice a day for 14 days...
February 20, 2024: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
https://read.qxmd.com/read/38378360/a-risk-model-for-parenteral-nutrition-associated-liver-disease-in-patients-with-severe-acute-pancreatitis
#14
JOURNAL ARTICLE
Zheng Chang, Hao Zhang
BACKGROUND AND STUDY AIMS: The aim of this study is to explore the risk factors for parenteral nutrition-associated liver disease (PNALD) in patients with severe acute pancreatitis by establishing a verification risk model. PATIENTS AND METHODS: A total of 176 patients with severe acute pancreatitis from January 2019 to August 2021, were assigned into the observation group (n = 88) and control group (n = 88) based on the diagnostic results of PNALD, randomly...
February 19, 2024: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
https://read.qxmd.com/read/38378359/diabetic-patients-with-chronic-hepatitis-c-virus-response-compared-to-non-diabetics-when-treated-with-directly-acting-antiviral-therapy
#15
JOURNAL ARTICLE
Raghda N Marzaban, Hesham I AlMekhzangy, Wafaa ElAkel, Tamer M ElBaz, Yehia M ElShazly, Kadry ElSaeed, Mahmoud Anees, Mohammed Said, Magdy A ElSerafy, Gamal G Esmat, Wahid H Doss
BACKGROUND AND STUDY AIMS: Hepatitis C virus (HCV) impairs glucose homoestasis, thus influences its clinical picture and prognosis. This study aimed at evaluating Diabetes mellitus (DM) on Egyptian patients with chronic hepatitis C (CHC), and its impact on their virologic response when treated with directly acting antiviral (DAA) medications. PATIENTS AND METHODS: Adult patients with CHC were divided into 2 groups; Diabetic patients, and Non diabetic patients serving as control group...
February 19, 2024: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
https://read.qxmd.com/read/38378358/effect-of-medium-chain-triglycerides-enriched-formula-on-growth-of-biliary-atresia-patients-after-kasai-portoenterostomy
#16
JOURNAL ARTICLE
Nehal El-Koofy, Eman Mahmoud, Fatma El Mougy, Engy Nasr, Sawsan Okasha, Hanaa El-Karaksy, Ghada Anwar, Mortada H El-Shabrawi, Nora E Badawi, Noha Arafa
BACKGROUND AND STUDY AIMS: Biliary atresia (BA) is the most common cause of neonatal cholestasis, negatively affecting nutritional status, growth, and development. It is the most frequent paediatric indication for liver transplantation. The Kasai portoenterostomy (KPE) operation is an effective procedure with favourable outcomes when performed before two months of age. The present study aimed to assess the nutritional status of patients with biliary atresia who underwent the Kasai operation and to evaluate the effectiveness of nutritional counselling using medium-chain triglyceride (MCT) formulas and proper supplementation on their nutritional status, growth, and vitamin D levels...
February 19, 2024: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
https://read.qxmd.com/read/38378357/dietary-composition-and-its-association-with-metabolic-dysfunction-associated-fatty-liver-disease-among-chinese-adults-a-cross-sectional-study
#17
JOURNAL ARTICLE
Zuohu Niu, Jing Liu, Hongye Peng, Xuan Wu, Xinzhuo Zheng, Shukun Yao, Chunjun Xu
BACKGROUND AND STUDY AIMS: Metabolic dysfunction-associated fatty liver disease (MAFLD) has become the most common cause of chronic liver disease worldwide. Diet plays a critical role in the prevention and treatment of MAFLD. Our hypothesis was that the intake of some macronutrients, vitamins, or mineral elements is associated with MAFLD. PATIENTS AND METHODS: Patients with MAFLD can be diagnosed based on the evidence of hepatic steatosis and if they meet any of the three additional criteria of overweight/obesity, diabetes mellitus, or metabolic dysregulation...
February 19, 2024: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
https://read.qxmd.com/read/38378356/mucormycosis-presenting-as-intestinal-perforation-a-pathologist-perspective
#18
Pallavi Saraf, Jyotsna Naresh Bharti
Mucormycosis is a life-threatening fungal infection mostly involving the ocular region, sinuses and brain. It is mostly seen in the immunocompromised host. Gastrointestinal (GI) mucormycosis is rare and mostly present as hematemesis, abdominal pain and melena. Here, we present a case of intestinal mucormycosis who presented as cecal perforation. Surgical resection was done, and the diagnosis was made by histopathology. Our case is unique in the way that GI mucormycosis is itself a rare entity and even rarer in an immunocompetent host...
February 19, 2024: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
https://read.qxmd.com/read/38378355/coronavirus-disease-19-covid-19-a-comparative-study-of-pattern-of-liver-injury-in-adult-patients-in-different-waves-of-covid-19-infection
#19
JOURNAL ARTICLE
Zeinab Abdellatif, Hanan Abdel-Haleem, Rasha Ahmed Abdalaziz, Ahmed Ramadan, Aya Mohamed Al-Sharif, Reem Ibrahim Mohamed El-Korashy, Youssef Mohamed Amin Soliman, Sabah Ahmed Hussein, Manal Mohamed Kamal, Mona Mohsen Abdulsalam Abdullatif, Mohammed Mustafa AbdelRazik, Noha Mohamed Tarek Eldessouky, Mira Atef
BACKGROUND AND STUDY AIMS: Liver dysfunction is a common manifestation of the COVID-19 infection. We aimed to study transaminase abnormalities through different waves of COVID-19 and their relations to disease severity or mortality. PATIENTS AND METHODS: A retrospective study included 521 Egyptian patients diagnosed with COVID-19. Data was retrieved from the medical records of patients who were admitted from April 2020 to October 2021 in Kasr Al-Ainy Hospitals, Cairo University, with categorization according to disease severity in correspondence to the four waves...
February 19, 2024: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
https://read.qxmd.com/read/38378354/effects-of-hmga2-on-the-biological-characteristics-and-stemness-acquisition-of-gastric-cancer-cells
#20
JOURNAL ARTICLE
Dequan Kong, Lang Zha, Yaben Yao, Zhenyu Zhang, Jun Gao, Rui Zhang, Lei Chen, Ziwei Wang
BACKGROUND AND STUDY AIMS: The high mobility group A2 (HMGA2), a nonhistone nuclear binding protein, modulates transcription by altering the chromatin architecture of the target gene DNA in its specific AT-hooks region. HMGA2 overexpression has been observed in embryonic tissue and many malignant neoplasms. This study sought to verify whether HMGA2 plays a role in the biological functions of gastric cancer cells, such as cell proliferation, invasiveness, migration, and stem cell acquisition, and to provide some ideas for further research on the metastatic mechanism of gastric cancer...
February 19, 2024: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
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