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Journals Journal of Medical Toxicology ...

Journal of Medical Toxicology : Official Journal of the American College of Medical Toxicology

https://read.qxmd.com/read/36988816/poison-centers-and-pediatric-environmental-health-specialty-units-productive-two-way-partnerships
#1
EDITORIAL
Alan D Woolf, Carl R Baum, Michele Burns
No abstract text is available yet for this article.
March 29, 2023: Journal of Medical Toxicology: Official Journal of the American College of Medical Toxicology
https://read.qxmd.com/read/36988815/response-to-comment-on-tacrolimus-drug-drug-interaction-with-nirmatrelvir-ritonavir-paxlovid%C3%A2-managed-with-phenytoin
#2
LETTER
Morganne Sindelar, Daniel McCabe, Elisabeth Carroll
No abstract text is available yet for this article.
March 29, 2023: Journal of Medical Toxicology: Official Journal of the American College of Medical Toxicology
https://read.qxmd.com/read/36988814/comment-on-tacrolimus-drug-drug-interaction-with-nirmatrelvir-ritonavir-paxlovid%C3%A2-managed-with-phenytoin
#3
LETTER
Luciana Mello de Oliveira, Tatiane da Silva Dal Pizzol
No abstract text is available yet for this article.
March 29, 2023: Journal of Medical Toxicology: Official Journal of the American College of Medical Toxicology
https://read.qxmd.com/read/36952114/2023-acmt-annual-scientific-meeting-abstracts-san-diego-ca
#4
(no author information available yet)
No abstract text is available yet for this article.
March 23, 2023: Journal of Medical Toxicology: Official Journal of the American College of Medical Toxicology
https://read.qxmd.com/read/36917213/our-appreciation-and-gratitude-to-journal-of-medical-toxicology-jmt-peer-reviewers-in-2022
#5
JOURNAL ARTICLE
Mark B Mycyk
No abstract text is available yet for this article.
March 14, 2023: Journal of Medical Toxicology: Official Journal of the American College of Medical Toxicology
https://read.qxmd.com/read/36892750/welcome-to-the-2023-acmt-annual-scientific-meeting-san-diego-ca
#6
EDITORIAL
Katherine L Boyle, Michael S Toce, Alison Meyn, Adrienne Dunavin, Maryann Mazer-Amirshahi
No abstract text is available yet for this article.
March 9, 2023: Journal of Medical Toxicology: Official Journal of the American College of Medical Toxicology
https://read.qxmd.com/read/36879004/fostering-the-next-generation-of-researchers-a-sustainable-mentoring-program-for-early-career-toxicologists-in-scientific-abstract-review
#7
JOURNAL ARTICLE
Mark B Mycyk, Christine M Murphy, Michael Chary, Peter R Chai, Adrienne Dunavin, Alison Meyn, Maryann Mazer-Amirshahi
The presentation of abstracts at scientific meetings is an important step in the dissemination of scientific discovery. Most scientific meetings recruit volunteer experts to evaluate and score submitted abstracts to determine which ones qualify for presentation. Reviewing an abstract is an important service to one's specialty, but there is typically no formal training or required instruction during medical toxicology fellowship on scientific abstract scoring. In order to provide structured training in abstract review, the American College of Medical Toxicology (ACMT) Research Committee launched the Annual Scientific Meeting (ASM) Abstract Review Mentor program in 2021...
March 6, 2023: Journal of Medical Toxicology: Official Journal of the American College of Medical Toxicology
https://read.qxmd.com/read/36877430/pediatric-suspected-suicides-and-nonfatal-suicide-attempts-reported-to-united-states-poison-control-centers-before-and-during-the-covid-19-pandemic
#8
JOURNAL ARTICLE
Hailee R Ciccotti, Henry A Spiller, Marcel J Casavant, Sandhya Kistamgari, Alexandra R Funk, Gary A Smith
INTRODUCTION: This study investigated the characteristics and compared the trends of pediatric suspected suicide and nonfatal suicide attempts reported to United States (US) poison control centers (PCCs) before and during the first year of the COVID-19 pandemic. METHODS: An interrupted time series analysis using an ARIMA model was conducted to evaluate the trends of suspected suicides and nonfatal suicide attempts among children 6-19 years old reported to the National Poison Data System during March 2020 through February 2021 (pandemic period) compared with March 2017 through February 2020 (pre-pandemic period)...
March 6, 2023: Journal of Medical Toxicology: Official Journal of the American College of Medical Toxicology
https://read.qxmd.com/read/36867315/response-to-comment-on-cardiovascular-and-adverse-effects-of-glucagon-for-the-management-of-suspected-beta-blocker-toxicity-a-case-series
#9
LETTER
Lorrie A LeClair, Alicia M Senart
No abstract text is available yet for this article.
March 3, 2023: Journal of Medical Toxicology: Official Journal of the American College of Medical Toxicology
https://read.qxmd.com/read/36867314/comment-on-cardiovascular-and-adverse-effects-of-glucagon-for-the-management-of-suspected-beta-blocker-toxicity-a-case-series
#10
LETTER
Marlis Gnirke, Brian G Wiener, Silas W Smith
No abstract text is available yet for this article.
March 3, 2023: Journal of Medical Toxicology: Official Journal of the American College of Medical Toxicology
https://read.qxmd.com/read/36862334/covid-19-therapeutics-use-mechanism-of-action-and-toxicity-vaccines-monoclonal-antibodies-and-immunotherapeutics
#11
REVIEW
Michael Chary, Alexander F Barbuto, Sudeh Izadmehr, Marc Tarsillo, Eduardo Fleischer, Michele M Burns
SARS-CoV-2 emerged in December 2019 and led to the COVID-19 pandemic. Efforts to develop therapeutics have led to innovations such as mRNA vaccines and oral antivirals. Here we provide a narrative review of the biologic therapeutics used or proposed to treat COVID-19 during the last 3 years. This paper, along with its companion that covers xenobiotics and alternative remedies, is an update to our 2020 paper. Monoclonal antibodies prevent progression to severe disease, are not equally effective across variants, and are associated with minimal and self-limited reactions...
March 2, 2023: Journal of Medical Toxicology: Official Journal of the American College of Medical Toxicology
https://read.qxmd.com/read/36757579/alteration-in-cerebral-metabolism-in-a-rodent-model-of-acute-sub-lethal-cyanide-poisoning
#12
JOURNAL ARTICLE
Oladunni Alomaja, Frances S Shofer, John C Greenwood, Sarah Piel, Carly Clayman, Clementina Mesaros, Shih-Han Kao, Samuel S Shin, Johannes K Ehinger, Todd J Kilbaugh, David H Jang
INTRODUCTION: Cyanide exposure can occur in various settings such as industry and metallurgy. The primary mechanism of injury is cellular hypoxia from Complex IV (CIV) inhibition. This leads to decreased ATP production and increased reactive oxygen species production. The brain and the heart are the organs most affected due to their high metabolic demand. While the cardiac effects of cyanide are well known, the cerebral effects on cellular function are less well described. We investigated cerebral metabolism with a combination of brain respirometry, microdialysis, and western blotting using a rodent model of sub-lethal cyanide poisoning...
February 9, 2023: Journal of Medical Toxicology: Official Journal of the American College of Medical Toxicology
https://read.qxmd.com/read/36757578/delta-8-tetrahydrocannabinol-exposure-and-confirmation-in-four-pediatric-patients
#13
JOURNAL ARTICLE
Kerollos Shaker, Andrea Nillas, Ross Ellison, Kelsey Martin, Jordan Trecki, Roy Gerona, Kim Aldy
INTRODUCTION: Delta-8-tetrahydrocannabinol (THC) is a known isomer of delta-9-THC, both found naturally in the Cannabis sativa plant and thought to have similar potency. Delta-8-THC products are widely accessible in retail shops which may lead to a rise in pediatric exposures with substantial clinical effects. CASE REPORT: This is a case series of four pediatric patients that were seen between June and September 2021. The patients presented with varied clinical symptoms including confusion, somnolence, seizure-like activity, hypotension, and tachycardia after exposure to delta-8-THC products obtained in retail shops...
February 9, 2023: Journal of Medical Toxicology: Official Journal of the American College of Medical Toxicology
https://read.qxmd.com/read/36650409/characterization-of-nonfatal-opioid-cocaine-methamphetamine-and-polydrug-exposure-and-clinical-presentations-reported-to-the-toxicology-investigators-consortium-core-registry-january-2010-december-2021
#14
JOURNAL ARTICLE
Emily Glidden, Kyle Suen, Desiree Mustaquim, Alana Vivolo-Kantor, Jeffery Brent, Paul Wax, Kim Aldy
INTRODUCTION: To characterize and compare opioid-only, cocaine-only, methamphetamine-only, opioid-and-cocaine exposure, and opioid-and-methamphetamine exposure and to examine clinical presentations, leading to a better understanding of overdose effects involving these drug exposures. METHODS: We examined drug exposures in the Toxicology Investigators Consortium (ToxIC) Core Registry from January 2010 to December 2021, a case registry of patients presenting to participating healthcare sites that receive a medical toxicology consultation...
January 17, 2023: Journal of Medical Toxicology: Official Journal of the American College of Medical Toxicology
https://read.qxmd.com/read/36479689/cardiovascular-and-adverse-effects-of-glucagon-for-the-management-of-suspected-beta-blocker-toxicity-a-case-series
#15
JOURNAL ARTICLE
Alicia M Senart, Lorrie A LeClair
BACKGROUND: Although glucagon use in beta blocker toxicity has been recommended for many years, evidence for its safety and efficacy in humans is limited. This study aims to determine the magnitude of effect of glucagon on heart rate (HR) and systolic blood pressure (SBP) in patients with suspected beta blocker toxicity and describe potential adverse effects of the medication. METHODS: We conducted a retrospective, multi-center case series of patients greater than 12 years of age who received glucagon for suspected beta blocker toxicity...
January 2023: Journal of Medical Toxicology: Official Journal of the American College of Medical Toxicology
https://read.qxmd.com/read/36575250/diphenhydramine-induced-antimuscarinic-delirium-treated-with-physostigmine-and-transdermal-rivastigmine
#16
JOURNAL ARTICLE
James D Whitledge, C James Watson, Michael Simpson, Azza Bakkar, Leora Boussi, Michael Scott, Katherine L Boyle
INTRODUCTION: Recurrent physostigmine shortages present a challenge to healthcare providers treating antimuscarinic delirium. Other centrally acting acetylcholinesterase inhibitors such as rivastigmine may represent a therapeutic alternative or adjunct during physostigmine shortage; however, previous reports of use have not documented serum antimuscarinic toxin concentrations, limiting evaluation of effectiveness. Combination therapy with physostigmine and rivastigmine has not been described...
December 27, 2022: Journal of Medical Toxicology: Official Journal of the American College of Medical Toxicology
https://read.qxmd.com/read/36542265/correction-to-biostatistics-and-epidemiology-principles-for-the-toxicologist-the-testy-test-characteristics-part-i-sensitivity-and-specificity
#17
Barbara Elena Sahagún, Christy Williams, Mark K Su
No abstract text is available yet for this article.
December 21, 2022: Journal of Medical Toxicology: Official Journal of the American College of Medical Toxicology
https://read.qxmd.com/read/36536192/tacrolimus-drug-drug-interaction-with-nirmatrelvir-ritonavir-paxlovid%C3%A2-managed-with-phenytoin
#18
JOURNAL ARTICLE
Morganne Sindelar, Daniel McCabe, Elisabeth Carroll
INTRODUCTION: The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 or COVID-19) pandemic has had a significant impact on communities and health systems. The Federal Drug Administration (FDA) authorized Pfizer's nirmatrelvir/ritonavir (Paxlovid™) through an EUA for the treatment of mild to moderate cases of COVID-19 at high risk for progression to severe disease. Patients with a history of transplant who test positive for COVID-19 are considered high risk because of their immunosuppression and are therefore candidates for nirmatrelvir/ritonavir...
December 19, 2022: Journal of Medical Toxicology: Official Journal of the American College of Medical Toxicology
https://read.qxmd.com/read/36536191/does-glucagon-really-work-for-beta-blocker-overdose
#19
EDITORIAL
Joanne C Routsolias, Sarah E Berg, Frank P Paloucek
No abstract text is available yet for this article.
December 19, 2022: Journal of Medical Toxicology: Official Journal of the American College of Medical Toxicology
https://read.qxmd.com/read/36525217/covid-19-therapeutics-use-mechanism-of-action-and-toxicity-xenobiotics
#20
REVIEW
Michael A Chary, Alexander F Barbuto, Sudeh Izadmehr, Marc Tarsillo, Eduardo Fleischer, Michele M Burns
SARS-CoV-2 emerged in 2019 and led to the COVID-19 pandemic. Efforts to develop therapeutics against SARS-Cov-2 led to both new treatments and attempts to repurpose existing medications. Here, we provide a narrative review of the xenobiotics and alternative remedies used or proposed to treat COVID-19. Most repositioned xenobiotics have had neither the feared toxicity nor the anticipated efficacy. Repurposed viral replication inhibitors are not efficacious and frequently associated with nausea, vomiting, and diarrhea...
December 16, 2022: Journal of Medical Toxicology: Official Journal of the American College of Medical Toxicology
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