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Nature Nanotechnology

Marta Autore, Rainer Hillenbrand
No abstract text is available yet for this article.
February 11, 2019: Nature Nanotechnology
Krishna Dan, Aneesh T Veetil, Kasturi Chakraborty, Yamuna Krishnan
Cellular reporters of enzyme activity are based on either fluorescent proteins or small molecules. Such reporters provide information corresponding to wherever inside cells the enzyme is maximally active and preclude minor populations present in subcellular compartments. Here we describe a chemical imaging strategy to selectively interrogate minor, subcellular pools of enzymatic activity. This new technology confines the detection chemistry to a designated organelle, enabling imaging of enzymatic cleavage exclusively within the organelle...
February 11, 2019: Nature Nanotechnology
In-Ho Lee, Daehan Yoo, Phaedon Avouris, Tony Low, Sang-Hyun Oh
One of the fundamental hurdles in plasmonics is the trade-off between electromagnetic field confinement and the coupling efficiency with free-space light, a consequence of the large momentum mismatch between the excitation source and plasmonic modes. Acoustic plasmons in graphene, in particular, have an extreme level of field confinement, as well as an extreme momentum mismatch. Here, we show that this fundamental compromise can be overcome and demonstrate a graphene acoustic plasmon resonator with nearly perfect absorption (94%) of incident mid-infrared light...
February 11, 2019: Nature Nanotechnology
Tapajyoti Das Gupta, Louis Martin-Monier, Wei Yan, Arthur Le Bris, Tùng Nguyen-Dang, Alexis Gérald Page, Kuan-Ting Ho, Filiz Yesilköy, Hatice Altug, Yunpeng Qu, Fabien Sorin
Modern devices require the tuning of the size, shape and spatial arrangement of nano-objects and their assemblies with nanometre-scale precision, over large-area and sometimes soft substrates. Such stringent requirements are beyond the reach of conventional lithographic techniques or self-assembly approaches. Here, we show nanoscale control over the fluid instabilities of optical thin glass films for the fabrication of self-assembled all-dielectric optical metasurfaces. We show and model the tailoring of the position, shape and size of nano-objects with feature sizes below 100 nm and with interparticle distances down to 10 nm...
February 11, 2019: Nature Nanotechnology
Tian Gu, Juejun Hu
No abstract text is available yet for this article.
February 11, 2019: Nature Nanotechnology
Tao Liu, Song Liu, Kun-Hua Tu, Hennrik Schmidt, Leiqiang Chu, Du Xiang, Jens Martin, Goki Eda, Caroline A Ross, Slaven Garaj
Two-dimensional transition metal dichalcogenide (TMD) materials, albeit promising candidates for applications in electronics and optoelectronics1-3 , are still limited by their low electrical mobility under ambient conditions. Efforts to improve device performance through a variety of routes, such as modification of contact metals4 and gate dielectrics5-9 or encapsulation in hexagonal boron nitride10 , have yielded limited success at room temperature. Here, we report a large increase in the performance of TMD field-effect transistors operating under ambient conditions, achieved by engineering the substrate's surface morphology...
February 4, 2019: Nature Nanotechnology
Denise M Mitrano, Anna Beltzung, Stefan Frehland, Michael Schmiedgruber, Alberto Cingolani, Felix Schmidt
Research on the distribution and effects of particulate plastic has intensified in recent years and yet, due to analytical challenges, our understanding of nanoplastic occurrence and behaviour has remained comparatively elusive. However, process studies could greatly aid in defining key parameters for nanoplastic interactions within and transfers between technical and environmental compartments. Here we provide a method to synthesize nanoplastic particles doped with a chemically entrapped metal used as a tracer, which provides a robust way to detect nanoplastics more easily, accurately and quantitatively in complex media...
February 4, 2019: Nature Nanotechnology
Jeffrey A Hubbell, Melody A Swartz
No abstract text is available yet for this article.
January 28, 2019: Nature Nanotechnology
Fei Peng, Magdiel Inggrid Setyawati, Jie Kai Tee, Xianguang Ding, Jinping Wang, Min En Nga, Han Kiat Ho, David Tai Leong
While most cancer nanomedicine is designed to eliminate cancer, the nanomaterial per se can lead to the formation of micrometre-sized gaps in the blood vessel endothelial walls. Nanomaterials-induced endothelial leakiness (NanoEL) might favour intravasation of surviving cancer cells into the surrounding vasculature and subsequently extravasation, accelerating metastasis. Here, we show that nanoparticles induce endothelial leakiness through disruption of the VE-cadherin-VE-cadherin homophilic interactions at the adherens junction...
January 28, 2019: Nature Nanotechnology
Tsveta S Malinova, Stephan Huveneers
No abstract text is available yet for this article.
January 28, 2019: Nature Nanotechnology
Shan Guan, Antje Munder, Silke Hedtfeld, Peter Braubach, Silke Glage, Longgui Zhang, Stefan Lienenklaus, Anja Schultze, Günther Hasenpusch, Wiebke Garrels, Frauke Stanke, Csaba Miskey, Sarah M Johler, Yadhu Kumar, Burkhard Tümmler, Carsten Rudolph, Zoltan Ivics, Joseph Rosenecker
Developing safe and efficient non-viral delivery systems remains a major challenge for in vivo applications of gene therapy, especially in cystic fibrosis. Unlike conventional cationic polymers or lipids, the emerging poloxamine-based copolymers display promising in vivo gene delivery capabilities. However, poloxamines are invalid for in vitro applications and their in vivo transfection efficiency is still low compared with viral vectors. Here, we show that peptides developed by modular design approaches can spontaneously form compact and monodisperse nanoparticles with poloxamines and nucleic acids via self-assembly...
January 28, 2019: Nature Nanotechnology
Jinwei Liu, Shihan Cheng, Na Cao, Chunxiang Geng, Chen He, Quan Shi, Chunming Xu, Jinren Ni, Ryan M DuChanois, Menachem Elimelech, Huazhang Zhao
In the version of the Supplementary Information file originally published with this Article, the images used for Supplementary Fig. 4 were incorrect and have now been replaced. This does not affect the results of the Article.
January 23, 2019: Nature Nanotechnology
Vivian P Vu, Geoffrey B Gifford, Fangfang Chen, Halli Benasutti, Guankui Wang, Ernest V Groman, Robert Scheinman, Laura Saba, Seyed Moein Moghimi, Dmitri Simberg
In the version of this Article originally published, a technical error led to Fig. 1a containing '!!!!!!!!' above the scale bar. This has now been corrected in all versions of the Article.
January 22, 2019: Nature Nanotechnology
Yuushou Hirata, Duck-Ho Kim, Se Kwon Kim, Dong-Kyu Lee, Se-Hyeok Oh, Dae-Yun Kim, Tomoe Nishimura, Takaya Okuno, Yasuhiro Futakawa, Hiroki Yoshikawa, Arata Tsukamoto, Yaroslav Tserkovnyak, Yoichi Shiota, Takahiro Moriyama, Sug-Bong Choe, Kyung-Jin Lee, Teruo Ono
In the presence of a magnetic field, the flow of charged particles in a conductor is deflected from the direction of the applied force, which gives rise to the ordinary Hall effect. Analogously, moving skyrmions with non-zero topological charges and finite fictitious magnetic fields exhibit the skyrmion Hall effect, which is detrimental for applications such as skyrmion racetrack memory. It was predicted that the skyrmion Hall effect vanishes for antiferromagnetic skyrmions because their fictitious magnetic field, proportional to net spin density, is zero...
January 21, 2019: Nature Nanotechnology
Peter R Wiecha, Aurélie Lecestre, Nicolas Mallet, Guilhem Larrieu
Diffraction drastically limits the bit density in optical data storage. To increase the storage density, alternative strategies involving supplementary recording dimensions and robust readout schemes must be explored. Here, we propose to encode multiple bits of information in the geometry of subwavelength dielectric nanostructures. A crucial problem in high-density information storage concepts is the robustness of the information readout with respect to fabrication errors and experimental noise. Using a machine-learning-based approach in which the scattering spectra are analysed by an artificial neural network, we achieve quasi-error-free readout of sequences of up to 9 bits, encoded in top-down fabricated silicon nanostructures...
January 21, 2019: Nature Nanotechnology
Andrey Miroshnichenko
No abstract text is available yet for this article.
January 21, 2019: Nature Nanotechnology
Ren Jie Lin, Vin-Cent Su, Shuming Wang, Mu Ku Chen, Tsung Lin Chung, Yu Han Chen, Hsin Yu Kuo, Jia-Wern Chen, Ji Chen, Yi-Teng Huang, Jung-Hsi Wang, Cheng Hung Chu, Pin Chieh Wu, Tao Li, Zhenlin Wang, Shining Zhu, Din Ping Tsai
A light-field camera captures both the intensity and the direction of incoming light1-5 . This enables a user to refocus pictures and afterwards reconstruct information on the depth of field. Research on light-field imaging can be divided into two components: acquisition and rendering. Microlens arrays have been used for acquisition, but obtaining broadband achromatic images with no spherical aberration remains challenging. Here, we describe a metalens array made of gallium nitride (GaN) nanoantennas6 that can be used to capture light-field information and demonstrate a full-colour light-field camera devoid of chromatic aberration...
January 21, 2019: Nature Nanotechnology
Anyuan Gao, Jiawei Lai, Yaojia Wang, Zhen Zhu, Junwen Zeng, Geliang Yu, Naizhou Wang, Wenchao Chen, Tianjun Cao, Weida Hu, Dong Sun, Xianhui Chen, Feng Miao, Yi Shi, Xiaomu Wang
Impact ionization, which supports carrier multiplication, is promising for applications in single photon detection1 and sharp threshold swing field effect devices2 . However, initiating the impact ionization of avalanche breakdown requires a high applied electric field in a long active region, which hampers carrier multiplication with a high gain, low bias and superior noise performance3,4 . Here we report the observation of ballistic avalanche phenomena in sub-mean free path (MFP) scaled vertical InSe/black phosphorus (BP)5-9 heterostructures10 ...
January 21, 2019: Nature Nanotechnology
Daniel Shae, Kyle W Becker, Plamen Christov, Dong Soo Yun, Abigail K R Lytton-Jean, Sema Sevimli, Manuel Ascano, Mark Kelley, Douglas B Johnson, Justin M Balko, John T Wilson
Cyclic dinucleotide (CDN) agonists of stimulator of interferon genes (STING) are a promising class of immunotherapeutics that activate innate immunity to increase tumour immunogenicity. However, the efficacy of CDNs is limited by drug delivery barriers, including poor cellular targeting, rapid clearance and inefficient transport to the cytosol where STING is localized. Here, we describe STING-activating nanoparticles (STING-NPs)-rationally designed polymersomes for enhanced cytosolic delivery of the endogenous CDN ligand for STING, 2'3' cyclic guanosine monophosphate-adenosine monophosphate (cGAMP)...
January 21, 2019: Nature Nanotechnology
Alan Shaw, Ian T Hoffecker, Ioanna Smyrlaki, Joao Rosa, Algirdas Grevys, Diane Bratlie, Inger Sandlie, Terje Einar Michaelsen, Jan Terje Andersen, Björn Högberg
Although repetitive patterns of antigens are crucial for certain immune responses, an understanding of how antibodies bind and dynamically interact with various spatial arrangements of molecules is lacking. Hence, we introduced a new method in which molecularly precise nanoscale patterns of antigens are displayed using DNA origami and immobilized in a surface plasmon resonance set-up. Using antibodies with identical antigen-binding domains, we found that all the subclasses and isotypes studied bind bivalently to two antigens separated at distances that range from 3 to 17 nm...
January 14, 2019: Nature Nanotechnology
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