América Martínez-Calleja, Irma Quiróz-Vargas, Isela Parra-Rojas, José Francisco Muñoz-Valle, Marco A Leyva-Vázquez, Gloria Fernández-Tilapa, Amalia Vences-Velázquez, Miguel Cruz, Eduardo Salazar-Martínez, Eugenia Flores-Alfaro
OBJECTIVE: We evaluated the association between four polymorphisms in the CRP gene with circulating levels of C-reactive protein (CRP), type 2 diabetes (T2D), obesity, and risk score of coronary heart disease. METHODS: We studied 402 individuals and classified them into four groups: healthy, obese, T2D obese, and T2D without obesity, from Guerrero, Southwestern Mexico. Blood levels of CRP, glucose, cholesterol, triglycerides, and leukocytes were measured. Genotyping was performed by PCR/RFLP, and the risk score for coronary heart disease was determined by the Framingham's methodology...
2012: Experimental Diabetes Research