journal
MENU ▼
Read by QxMD icon Read
search

International Journal of Stroke: Official Journal of the International Stroke Society

journal
https://read.qxmd.com/read/30762497/management-of-oral-anticoagulation-after-intracerebral-hemorrhage
#1
Joji B Kuramatsu, Hagen B Huttner
BACKGROUND: The most recent years have significantly expanded knowledge regarding risks and benefits of resuming oral anticoagulation (OAC) after intracerebral hemorrhage (ICH). No randomized data is yet available, though several large observational studies and meta-analyses have investigated the impact of resuming OAC on thromboembolic versus hemorrhagic complications in these high-risk patients after ICH. AIMS: The present review will summarize the most important studies conducted over the last years and will focus on relevant factors help guiding on decision-making on whether to start OAC after ICH...
February 14, 2019: International Journal of Stroke: Official Journal of the International Stroke Society
https://read.qxmd.com/read/30762496/perivascular-spaces-and-their-associations-with-risk-factors-clinical-disorders-and-neuroimaging-features-a-systematic-review-and-meta-analysis
#2
Farah Francis, Lucia Ballerini, Joanna M Wardlaw
BACKGROUND: Perivascular spaces, visible on brain magnetic resonance imaging, are thought to be associated with small vessel disease, neuroinflammation, and to be important for cerebral hemodynamics and interstitial fluid drainage. AIMS: To benchmark current knowledge on perivascular spaces associations with risk factors, neurological disorders, and neuroimaging lesions, using systematic review and meta-analysis. SUMMARY OF REVIEW: We searched three databases for perivascular spaces publications, calculated odds ratios with 95% confidence interval and performed meta-analyses to assess adjusted associations with perivascular spaces...
February 14, 2019: International Journal of Stroke: Official Journal of the International Stroke Society
https://read.qxmd.com/read/30758278/the-effect-of-cerebellar-transcranial-direct-current-stimulation-to-improve-standing-balance-performance-early-post-stroke-study-protocol-of-a-randomized-controlled-trial
#3
Sarah B Zandvliet, Carel Gm Meskers, Rinske Hm Nijland, Andreas Daffertshofer, Gert Kwakkel, Erwin Eh van Wegen
RATIONALE: Restoration of adequate standing balance after stroke is of major importance for functional recovery. POstural feedback ThErapy combined with Non-invasive TranscranIAL direct current stimulation (tDCS) in patients with stroke (POTENTIAL) aims to establish if cerebellar tDCS has added value in improving standing balance performance early post-stroke. METHODS: Forty-six patients with a first-ever ischemic stroke will be enrolled in this double-blind controlled trial within five weeks post-stroke...
February 13, 2019: International Journal of Stroke: Official Journal of the International Stroke Society
https://read.qxmd.com/read/30758277/cost-utility-analysis-of-mechanical-thrombectomy-between-6-and-24-hours-in-acute-ischemic-stroke
#4
Elena Pizzo, Maureen Dumba, Kyriakos Lobotesis
BACKGROUND: Recently, two randomized controlled trials demonstrated the benefit of mechanical thrombectomy performed between 6 and 24 h in acute ischemic stroke. The current economic evidence is supporting the intervention only within 6 h, but extended thrombectomy treatment times may result in better long-term outcomes for a larger cohort of patients. AIMS: We compared the cost-utility of mechanical thrombectomy in addition to medical treatment versus medical treatment alone performed beyond 6 h from stroke onset in the UK National Health Service (NHS)...
February 13, 2019: International Journal of Stroke: Official Journal of the International Stroke Society
https://read.qxmd.com/read/30758276/targets-for-improving-dispatcher-identification-of-acute-stroke
#5
Olli S Mattila, Tuukka Puolakka, Juhani Ritvonen, Saana Pihlasviita, Heini Harve, Ari Alanen, Gerli Sibolt, Sami Curtze, Daniel Strbian, Mikko Pystynen, Turgut Tatlisumak, Markku Kuisma, Perttu J Lindsberg
BACKGROUND: Accurate identification of acute stroke by Emergency Medical Dispatchers (EMD) is essential for timely and purposeful deployment of Emergency Medical Services (EMS), and a prerequisite for operating mobile stroke units. However, precision of EMD stroke recognition is currently modest. AIMS: We sought to identify targets for improving dispatcher stroke identification. METHODS: Dispatch codes and EMS patient records were cross-linked to investigate factors associated with an incorrect dispatch code in a prospective observational cohort of 625 patients with a final diagnosis of acute stroke or transient ischemic attack (TIA), transported to our stroke center as candidates for recanalization therapies...
February 13, 2019: International Journal of Stroke: Official Journal of the International Stroke Society
https://read.qxmd.com/read/30747614/location-specific-differences-in-hematoma-volume-predict-outcomes-in-patients-with-spontaneous-intracerebral-hemorrhage
#6
Natasha Ironside, Ching-Jen Chen, Victoria Dreyer, Brandon Christophe, Thomas J Buell, Edward Sander Connolly
BACKGROUND AND OBJECTIVE: Functional outcome after spontaneous intracerebral hemorrhage (ICH) may vary depending on hematoma volume and location. We assessed the interaction between hematoma volume and location, and modified the original ICH score to include such an interaction. METHODS: Consecutive ICH patients were enrolled in the Intracerebral Hemorrhage Outcomes Project from 2009 to 2017. Inclusion criteria were age≥18 years, baseline modified Rankin Scale (mRS) score 0-2, neuroimaging, and follow-up...
February 12, 2019: International Journal of Stroke: Official Journal of the International Stroke Society
https://read.qxmd.com/read/30747613/the-acute-stroke-or-transient-ischemic-attack-treated-with-ticagrelor-and-aspirin-for-prevention-of-stroke-and-death-thales-trial-rationale-and-design
#7
S Claiborne Johnston, Pierre Amarenco, Hans Denison, Scott R Evans, Anders Himmelmann, Stefan James, Mikael Knutsson, Per Ladenvall, Carlos A Molina, Yongjun Wang
RATIONALE: In patients with acute cerebral ischemia, the rate of stroke, myocardial infarction, or death during 90 days was reported to be non-significantly lower with ticagrelor compared with aspirin, with no increase in major hemorrhage. Dual antiplatelet therapy may be more effective in this setting. AIM: To investigate whether ticagrelor combined with aspirin are superior to aspirin alone in preventing stroke or death in patients with non-severe, non-cardioembolic ischemic stroke or high-risk transient ischemic attack...
February 12, 2019: International Journal of Stroke: Official Journal of the International Stroke Society
https://read.qxmd.com/read/30747612/utility-weighted-modified-rankin-scale-still-too-crude-to-be-a-truly-patient-centric-primary-outcome-measure
#8
Venesha Rethnam, Julie Bernhardt, Helen Dewey, Marj Moodie, Hannah Johns, Lan Gao, Janice Collier, Fiona Ellery, Leonid Churilov
BACKGROUND: The utility-weighted modified Rankin Scale (UW-mRS) is an outcome measure recently proposed to improve statistical efficiency and interpretability of the mRS. Statistical properties of the UW-mRS have been well investigated, but construct validity has yet to be established. AIMS: To investigate the construct validity of the UW-mRS as a primary outcome measure by assessing variability in utility values within and between mRS categories, over time post-stroke, and by different derivation methods...
February 12, 2019: International Journal of Stroke: Official Journal of the International Stroke Society
https://read.qxmd.com/read/30747597/cerebral-microbleeds-beyond-the-macroscope
#9
Maud Pétrault, Barbara Casolla, Thavarak Ouk, Charlotte Cordonnier, Vincent Bérézowski
While being increasingly recognized in clinical routine, brain microbleeds remain a puzzling finding for physicians. These small dot-like lesions are thought to be old perivascular collections of hemosiderin deposits. They can be found in different neurological settings such as cerebrovascular or neurodegenerative diseases. While their microscopic size would suggest considering these lesions as anecdotal, they are now regarded as biomarkers of severity of an underlying cerebrovascular disease. Their natural history and the interactions with surrounding brain cells remain unknown...
February 12, 2019: International Journal of Stroke: Official Journal of the International Stroke Society
https://read.qxmd.com/read/30741611/burden-of-large-vessel-occlusion-stroke-and-the-service-gap-of-thrombectomy-a-population-based-study-using-a-territory-wide-public-hospital-system-registry
#10
Anderson C O Tsang, Jia You, Lai Fung Li, Frederick C P Tsang, Pauline P S Woo, Eva L H Tsui, Philip Yu, Gilberto K K Leung
BACKGROUND: Ischemic stroke due to large vessel occlusion can be effectively treated with thrombectomy but access to this treatment is limited in many parts of the world. Local incidence of large vessel occlusion is critical in determining the development of thrombectomy service, but reliable data from Asian countries are lacking. AIMS: We performed a population-based study to estimate the burden of large vessel occlusion and the service gap for thrombectomy in Hong Kong...
February 11, 2019: International Journal of Stroke: Official Journal of the International Stroke Society
https://read.qxmd.com/read/30734663/transient-ischemic-attack-incidence-and-early-risk-of-stroke-in-northern-portugal-from-1998-2000-to-2009-2011
#11
Rui Felgueiras, Rui Magalhães, Mário R Silva, Maria C Silva, Manuel Correia
OBJECTIVE: A decline in TIA incidence would be expected mirroring stroke trends, but patient's awareness of symptoms/signs, improved diagnostic procedures and changes in severity of vascular disease may raise TIA incidence. We aimed to estimate changes in TIA incidence and 30-day stroke risk in Portugal. METHODS: Data from two prospective community-based registers of first-ever TIA in 104,700 (1998-2000) and 118,232 (2009-2011) persons were collected using comprehensive case ascertainment methods...
February 8, 2019: International Journal of Stroke: Official Journal of the International Stroke Society
https://read.qxmd.com/read/30722756/diagnosis-and-management-of-carotid-free-floating-thrombus-a-systematic-literature-review
#12
Sebastian Fridman, Stephen P Lownie, Jennifer Mandzia
BACKGROUND: There is no consensus regarding the management of carotid free-floating thrombi in patients with acute ischemic stroke and transient ischemic attack. AIMS: This systematic review aims to (1) describe the current imaging methods for diagnosis of carotid free-floating thrombi and its associated risk factors, (2) estimate the proportion of carotid free-floating thrombi diagnosed in stroke patients, (3) estimate the proportion of carotid free-floating thrombi patients treated medically and surgically, and (4) evaluate 30-day outcomes...
February 6, 2019: International Journal of Stroke: Official Journal of the International Stroke Society
https://read.qxmd.com/read/30722755/new-opportunities-to-optimize-antithrombotic-therapy-for-secondary-stroke-prevention
#13
Anthony S Kim, J Donald Easton
Stroke symptoms can be unsettling, even when symptoms resolve, but focusing on stroke prevention can be empowering provided that effective interventions for appropriate patient populations are available. Current options include interventions for symptomatic carotid artery stenosis, anticoagulation for atrial fibrillation, high-dose statins, new oral anticoagulants, new developments in atrial fibrillation detection, and new therapeutics are in development. For antiplatelet therapy, aspirin monotherapy is effective but dual antiplatelet therapy with the combination of aspirin and clopidogrel increases hemorrhage risks over the long term that outweigh potential benefits...
February 6, 2019: International Journal of Stroke: Official Journal of the International Stroke Society
https://read.qxmd.com/read/30707084/impact-of-prehospital-stroke-code-in-a-public-center-in-paraguay-a-pilot-study
#14
Alan Flores, Laia Seró, Christian Otto, Ricardo Mernes, Silvia Gonzalez, Luis Diaz-Escobar, Romina Gonzalez
Prehospital stroke code activation results in reduced pre- and in-hospital delays and triage and transport of stroke patients to the right centers. In Paraguay, data about acute reper fusion treatment are not available. Recently, a pilot prehospital stroke code program was implemented in the country in November 2016. In an observational, single-center cohort study with a before-after design, from April 2015 to July 2018, we found that 193/832 (23.1%) of stroke patients were stroke code activated, and from these, 54 (6...
February 1, 2019: International Journal of Stroke: Official Journal of the International Stroke Society
https://read.qxmd.com/read/30702415/regional-differences-in-ischemic-stroke-in-india-north-vs-south
#15
Vishnu Y Venugopalan, Rohit Bhatia, Jeyaraj Pandian, Dheeraj Khurana, Subhash Kaul, P N Sylaja, Deepti Arora, Himani Khatter, M V Padma, Aneesh B Singhal
BACKGROUND: India is a large country with geographically diverse populations and varying risk factors. Identification of regional differences can improve healthcare policy decisions. AIM: To study regional differences in stroke between North and South India. METHODS: We analyzed data from the Indo-US Collaborative Stroke Project, a National Institute of Health-funded multicentre prospective study conducted in five academic centers in India with a US-based coordinating center...
January 31, 2019: International Journal of Stroke: Official Journal of the International Stroke Society
https://read.qxmd.com/read/30681042/high-in-hospital-blood-pressure-variability-and-severe-disability-or-death-in-primary-intracerebral-hemorrhage-patients
#16
Jennifer R Meeks, Arvind B Bambhroliya, Elizabeth G Meyer, Kristen B Slaughter, Christopher J Fraher, Anjail Z Sharrief, Ritvij Bowry, Wamda O Ahmed, Jon E Tyson, Charles C Miller, Steve Warach, Babar A Khan, Louise D McCullough, Sean I Savitz, Farhaan S Vahidy
OBJECTIVE: To quantify in-hospital systolic blood pressure variability among patients with intracerebral hemorrhage, determine the association between high systolic blood pressure variability (HSBPV) and 90-day severe disability or death, and examine the association between pre-hospital factors and HSBPV. METHODS: Adult, radiologically confirmed, intracerebral hemorrhage patients enrolled in a multi-site cohort were included. Using a semi-automated algorithm, systolic blood pressure values recorded from routine non-invasive systolic blood pressure monitoring in critical and acute care settings were extracted for the duration of hospitalization...
January 25, 2019: International Journal of Stroke: Official Journal of the International Stroke Society
https://read.qxmd.com/read/30681041/the-potential-of-m-health-based-interventions-to-improve-medication-literacy-and-adherence-in-non-communicable-diseases-in-pakistan
#17
Ayeesha Kamran Kamal, Wardah Khalid, Maryam Zulfiqar, Abdul Muqeet, Fabiha Zaidi, Ambreen Gowani, Salim S Virani
No abstract text is available yet for this article.
January 25, 2019: International Journal of Stroke: Official Journal of the International Stroke Society
https://read.qxmd.com/read/30644794/anticoagulation-in-patients-with-embolic-stroke-of-unknown-source
#18
J David Spence
When warfarin was the mainstay of anticoagulation for the prevention of cardioembolic stroke, the paradigm was essentially "we mustn't anticoagulate anyone unless we prove that the stroke was cardioembolic." Now that direct-acting oral anticoagulants are available, the paradigm should change. The risk of stroke is highest soon after the initial event, particularly in patients with more than one infarction. Direct-acting oral anticoagulants are not significantly more likely than aspirin to cause severe hemorrhage, and it is now clear that patients with paradoxical embolism are better treated with anticoagulant than aspirin...
January 15, 2019: International Journal of Stroke: Official Journal of the International Stroke Society
https://read.qxmd.com/read/30632954/advanced-clinical-education-for-stroke-physicians-in-china-the-action-and-sca-models
#19
Shaoshi Wang, Stephen Davis, Qiang Dong, Yongjun Wang, Liping Liu, Huazheng Liang, Bernard Yan
No abstract text is available yet for this article.
January 11, 2019: International Journal of Stroke: Official Journal of the International Stroke Society
https://read.qxmd.com/read/30632953/contemporary-prognosis-of-transient-ischemic-attack-patients-a-systematic-review-and-meta-analysis
#20
Nashwa Najib, Parker Magin, Daniel Lasserson, Debbie Quain, John Attia, Christopher Oldmeadow, Carlos Garcia-Esperon, Christopher Levi
BACKGROUND: Transient ischemic attacks are common and place patients at risk of subsequent stroke. The 2007 EXPRESS and SOS-TIA studies demonstrated the efficacy of rapid treatment initiation. We hypothesized that with these findings having informed subsequent transient ischemic attacks management protocols, transient ischemic attacks prognosis in contemporary (2008 and later) patient cohorts would be more favorable than in historical cohorts. METHODS: A systematic review and meta-analysis of cohort studies and randomized control trial placebo-arms of transient ischemic attack (published 2008-2015)...
January 11, 2019: International Journal of Stroke: Official Journal of the International Stroke Society
journal
journal
41360
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"