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Hospital Practice (Minneapolis)

Steven G Chrysant, George S Chrysant
OBJECTIVES: Obesity has risen in the US and worldwide, and has become a major risk factor for type 2 diabetes mellitus (T2DM), hypertension, cardiovascular disease, and heart failure (HF), mostly HF with preserved ejection fraction (HFpEF). Also, the prevalence of HF is quite high in the US accounting for 6.6 million adults at present and is projected to reach 8.5 million by the year 2030 and is equally divided between HFpEF and heart failure reduced ejection fraction (HFrEF). Patients with HFpEF are resistant to treatment with drugs usually used for the treatment of HFrEF, but the reasons for this resistance are not clearly known...
February 4, 2019: Hospital Practice (Minneapolis)
Hussam A Yacoub, P Mark Li, Joshua A Bemporad, Dmitry Khaitov, Daniel F Brown
Hypertrophic pachymeningitis (HP) is a chronic, progressive diffuse inflammatory condition that leads to thickening of the dura mater and can be idiopathic or associated with sarcoidosis among other disorders. In this case report, we present a rare case of cervical spine HP in a 29-year-old woman in the post-partum period, who had a history of pituitary adenoma and juvenile rheumatoid arthritis. Magnetic resonance imaging (MRI) of the spine revealed a soft tissue mass and moderate cord compression. The patient underwent C3-C7 laminectomy...
January 25, 2019: Hospital Practice (Minneapolis)
Charat Thongprayoon, Wisit Cheungpasitporn, Michael A Mao, Andrew M Harrison, Stephen B Erickson
BACKGROUND: Increased serum calcium-phosphate product (CaP) can result in acute kidney injury (AKI) due to tubular and interstitial calcium phosphate deposits. CaP of >55 mg2 /dL2 is also associated with systemic calcification. However, the risk of AKI development among hospitalized patients with different admission calcium-phosphate product levels remains unclear. METHODS: All adult hospitalized patients who had both admission serum calcium and phosphate levels available from 2009 through 2013 were enrolled...
January 11, 2019: Hospital Practice (Minneapolis)
Eric M Ammann, Laura J Goldstein, Deborah Nagle, David Wei, Stephen S Johnston
OBJECTIVES: The economic burden of surgical complications is borne in distinctly different ways by hospitals and payers. This study quantified the incidence and economic burden-from both the hospital and payer perspective-of selected major colorectal surgery complications in patients undergoing low anterior resection (LAR) for colorectal cancer. METHODS: Retrospective, observational study of patient undergoing LAR for colorectal cancer between 1/1/2010-7/1/2015...
January 11, 2019: Hospital Practice (Minneapolis)
John R Stephens, Jamison W Chang, E Allen Liles, Mukhtar Adem, Carlton Moore
OBJECTIVES: Hip fracture is a common and morbid condition, affecting a patient population with significant medical co-morbidities. A number of medical co-management models have been studied, with conflicting reports of effect on patient outcomes. Our objective was to compare outcomes for patients with hip fracture managed by hospitalist vs. non-hospitalist services at an academic medical center. METHODS: We conducted a retrospective cohort study of patients with hip fracture over 1 year, comparing those on hospitalist vs...
February 2019: Hospital Practice (Minneapolis)
Matteo Bassetti, Antonio Vena, Alessandro Russo
Septic shock represents a serious complication occurring between 6% and 30% of all hospitalized patients; Candida septic shock represents a challenge for clinicians due to the absence of specific risk factors, diagnostic tests, and management. Identification of specific risk factors and use of biomarkers are useful tools considering that differentiation of Candida from bacterial septic shock is demanding. Early effective antifungal treatment, preferably with echinocandins with an adequate source control, represents the best approach for improving survival of patients with septic shock due to Candida...
December 2018: Hospital Practice (Minneapolis)
Wisit Kaewput, Charat Thongprayoon, Ram Rangsin, Michael A Mao, Bancha Satirapoj, Wisit Cheungpasitporn
BACKGROUND: The evidence for an association between renal function and neurological diseases among type 2 diabetes mellitus (T2DM) patients, particularly in the Asian population, is limited. This study aimed to assess the association between glomerular filtration rate (GFR) and various neurological diseases among T2DM patients in Thailand using a nationwide patient sample. METHODS: We conducted a nationwide cross-sectional study based on the DM/HT study of the Medical Research Network of the Consortium of Thai Medical Schools...
November 16, 2018: Hospital Practice (Minneapolis)
Areeba Kara, Dawson Frank Dean, Cynthia S Johnson, Siu L Hui
BACKGROUND: Rapid response teams (RRTs) improve mortality by intervening in the hours preceding arrest. Implementation of these teams varies across institutions. SETTING AND DESIGN: Our health-care system has two different RRT models at two hospitals: Hospital A does not utilize a proactive rounder while Hospital B does. We studied the patterns of RRT calls at each hospital focusing on the differences between night and day and during nursing shift transitions. RESULTS: The presence of proactive surveillance appeared to be associated with an increased total number of RRT calls with more than twice as many calls made at the smaller Hospital B than Hospital A...
November 8, 2018: Hospital Practice (Minneapolis)
Stamatis J Karakatsanis, Stamatis S Papadatos, Konstantinos N Syrigos
Platelet transfusions consist a major part of the management of hypoplastic thrombocytopenia, the latter occurring mainly among patients with hematological malignancies. Platelet transfusions have led to a reduction of deaths attributable to thrombocytopenia-induced bleeding, despite their possible complications; nonetheless, prophylactic administration of platelets to patients with severe thrombocytopenia or before invasive procedures should be based on specific criteria, as well as therapeutic administration during active bleeding...
November 8, 2018: Hospital Practice (Minneapolis)
Javier Pemán, Alba Ruiz-Gaitán
No abstract text is available yet for this article.
October 18, 2018: Hospital Practice (Minneapolis)
Sean Marks, John Paul Wanner, Ashley S Cobb, Keith M Swetz, George M Lange
BACKGROUND: There has been little published research regarding the implementation of healthcare power of attorney (HCPOA) documents prior to elective surgery. OBJECTIVES: This study aims to determine the prevalence of HCPOA documents incorporated into the electronic medical records (EMR) of patients undergoing elective surgery at four healthcare institutions. A secondary aim is to examine for correlations between HCPOA document implementation and demographic and preoperative clinical predictors...
October 17, 2018: Hospital Practice (Minneapolis)
Godfrey M Rwegerera, Anthony Masaka, Yordanka Pina-Rivera, Thato Moshomo, Marea Gaenamong, Brian Godman, Taibat Aderonke Oyewo, Amos Massele, Dereje Habte
BACKGROUND AND AIMS: Glycemic control among patients with diabetes mellitus is associated with a marked reduction of both macrovascular and microvascular complications; however, glycemic control remains an elusive goal worldwide. The aim of this study was to determine factors associated with glycemic control among patients attending a tertiary clinic in Botswana as limited information to date. METHODS: Cross-sectional study in a tertiary clinic in Gaborone, Botswana...
October 12, 2018: Hospital Practice (Minneapolis)
Lee-Anne Godinho, Charles Feldman
OBJECTIVES: The incidence of Clostridium difficile infection is increasing, resulting in significant in-patient morbidity and mortality. We describe the characteristics of Clostridium difficile infection in patients admitted to a tertiary Academic Hospital in Johannesburg, South Africa. METHODS: This was a retrospective record review of 154 adult in-patients with confirmed Clostridium difficile infection undertaken between 1 January 2013 and 30 June 2014. RESULTS: Overall, 83 (53...
October 12, 2018: Hospital Practice (Minneapolis)
Omar Abughanimeh, Ayman Qasrawi, Osama Kaddourah, Laith Al Momani, Mouhanna Abu Ghanimeh
Clostridium difficile infection (CDI) is one of the most common healthcare-associated infections in the United States. Its incidence has been increasing in the recent years despite preventative measures. CDI increases annual expenses by 1.5 billion dollars. Cancer patients are at higher risk to acquire CDI, as explained by their frequent exposure to risk factors. CDI in cancer patients is associated with higher mortality rates and prolonged hospitalization. Furthermore, CDI affects the course of the disease by delaying treatments such as chemotherapy...
October 8, 2018: Hospital Practice (Minneapolis)
Antionette Terblanche, Johanna Catharina Meyer, Brian Godman, Robert Stanley Summers
BACKGROUND AND AIMS: Under-reporting of adverse drug reactions (ADRs) by health-care professionals (HCPs) is a worldwide problem. Spontaneous reporting in hospitals is scarce and several obstacles have been identified for this. Improved hospital-based reports could make important contributions to future care. Consequently, the objective of this study was to develop, implement and evaluate a structured pharmacist-driven pharmacovigilance (PV) system for in-patient ADR reporting in a leading public hospital in South Africa for future use in South Africa and wider...
October 2018: Hospital Practice (Minneapolis)
Pratyusha Vadagam, Khalid M Kamal
OBJECTIVE: To determine patient, hospital, and clinical characteristics associated with the length of stay (LOS), total hospital charges, and total hospital costs in cystic fibrosis (CF). METHODS: Hospital discharge records with primary and secondary diagnoses of CF were identified from the 2012 Kids' Inpatient Database (KID) consisting of inpatient records of ages 0-20 years; and 2012 National Inpatient Sample (NIS) consisting of inpatient records of ages 21 and above...
October 2018: Hospital Practice (Minneapolis)
Sarah Eisho, Nouran M Salem, Janet L Hoffman, John M Koerber, Maureen A Smythe
OBJECTIVES: To identify patient characteristics, bleed management, and bleed outcomes in patients experiencing an apixaban major bleeding event and to identify opportunities to improve the safe use of apixaban. METHODS: This retrospective single health-system study identified apixaban patients experiencing a major bleeding event between January 2013 and May 2016 through electronic medical record review. Patient characteristics, bleed management, and outcomes were extracted in those with a confirmed major bleed assessed by the International Society on Thrombosis and Haemostasis criteria...
October 2018: Hospital Practice (Minneapolis)
Godfrey Mutashambara Rwegerera, Onkabetse Julia Molefe-Baikai, Anthony Masaka, Meshack Shimwela, Yordanka Pina Rivera, Taibat Aderonke Oyewo, Brian B Godman, Amos Massele, Dereje Habte
OBJECTIVES: Diabetes mellitus (DM) is one of the most common contributors of chronic kidney disease (CKD). The epidemiology of CKD, a concern among patients with DM, has not been studied in Botswana. Consequently, the objective of this study was to estimate its prevalence among these patients in Botswana to provide future guidance to both government personnel and physicians. METHODS: Observational cross-sectional study in a leading clinic in Botswana. Demographic and clinical data were obtained from patients through interviews and from their notes using a standard questionnaire...
October 2018: Hospital Practice (Minneapolis)
E Carlos Rodriguez-Merchan
INTRODUCTION: Knee osteoarthritis (OA) is one of the preeminent musculoskeletal illnesses in the adult population. AIM: To investigate the role of intra-articular injections of joint fat-derived mesenchymal stem cells (MSCs) in knee OA. METHODS: A Cochrane Library and PubMed (MEDLINE) search related to the role of intra-articular injections of joint fat-derived MSCs in knee OA was analyzed. RESULTS: Experimental and clinical studies on intra-articular injections of joint fat-derived MSCs have provided satisfactory results (pain relief) in the short term...
October 2018: Hospital Practice (Minneapolis)
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