journal
https://read.qxmd.com/read/38664956/adaptive-thermogenesis-at-the-level-of-resting-energy-expenditure-after-diet-alone-or-diet-plus-bariatric-surgery
#21
JOURNAL ARTICLE
Silvia Y Lopez Torres, Marthe I Aukan, Barbara A Gower, Catia Martins
OBJECTIVE: The objective of this study was to compare the magnitude of adaptive thermogenesis (AT), at the level of resting energy expenditure (REE), after a very low-energy diet alone or combined with Roux-en-Y gastric bypass or sleeve gastrectomy, as well as to investigate the association between AT and changes in appetite. METHODS: A total of 44 participants with severe obesity underwent 10 weeks of a very low-energy diet alone or combined with Roux-en-Y gastric bypass or sleeve gastrectomy...
April 25, 2024: Obesity
https://read.qxmd.com/read/38664858/correction-to-nadph-oxidase-4-in-mouse-%C3%AE-cells-participates-in-inflammation-on-chronic-nutrient-overload
#22
(no author information available yet)
No abstract text is available yet for this article.
April 25, 2024: Obesity
https://read.qxmd.com/read/38664310/obesity-related-inflammatory-protein-signature-in-cardiovascular-clinical-outcomes-results-from-the-gutenberg-health-study
#23
JOURNAL ARTICLE
Marina Panova-Noeva, Thomas Koeck, Corinna Schoelch, Andreas Schulz, Jürgen H Prochaska, Matthias Michal, Konstantin Strauch, Alexander K Schuster, Karl J Lackner, Thomas Münzel, Anita M Hennige, Philipp S Wild
OBJECTIVE: The objective of this study was to investigate whether an obesity-related inflammatory protein signature (OIPS) is associated with adverse cardiovascular events. METHODS: The Olink Target 96 Inflammation panel was performed in 6662 participants from the population-based Gutenberg Health Study (GHS). The OIPS was selected by a logistic regression model, and its association with cardiovascular outcomes was evaluated by Cox regression analysis. The GHS-derived OIPS was externally validated in the MyoVasc study...
April 25, 2024: Obesity
https://read.qxmd.com/read/38664236/body-weight-variability-and-the-risk-of-liver-related-outcomes-in-type-2-diabetes-and-steatotic-liver-disease-a-cohort-study
#24
JOURNAL ARTICLE
Nathalie C Leite, Claudia R L Cardoso, Cristiane A Villela-Nogueira, Gil F Salles
OBJECTIVE: The objective of this study was to evaluate the effects of body weight variability (BWV) on the occurrence of adverse liver outcomes in individuals with type 2 diabetes (T2D) and metabolic dysfunction-associated steatotic liver disease (MASLD). METHODS: A total of 549 patients with T2D and MASLD had BWV parameters assessed during the first 2 years of follow-up. The associations between increasing BWV and liver outcomes (clinical cirrhosis or a liver stiffness measurement on transient elastography > 15 kPa, performed after a median of 7 years of cohort entry) were examined by multivariable logistic regressions...
April 25, 2024: Obesity
https://read.qxmd.com/read/38664233/presurgery-health-influences-outcomes-following-vertical-sleeve-gastrectomy-in-adolescents
#25
JOURNAL ARTICLE
Debi Swertfeger, Ahlee Kim, Hannah Sexmith, Maria E Moreno-Fernandez, W Sean Davidson, Michael Helmrath, Todd Jenkins, Tsuyoshi Okura, Esmond Geh, Stavra A Xanthakos, Sara Szabo, Takahisa Nakamura, Senad Divanovic, Amy Sanghavi Shah
OBJECTIVE: Weight loss following vertical sleeve gastrectomy (VSG) in youth can range from 10% to 50%. We examined whether there are differences in demographic or metabolic parameters before VSG in youth who achieve above-average weight loss (AAWL) versus below-average weight loss (BAWL) at 1 year post VSG and if youth with BAWL still achieve metabolic health improvements at 1 year post VSG. METHODS: Demographic, anthropometric, and clinical lab data were collected before VSG and at 1, 3, 6, and 12 months after VSG...
April 25, 2024: Obesity
https://read.qxmd.com/read/38659126/response-to-fitch-and-huett-garcia
#26
LETTER
Hamlet Gasoyan, Elizabeth R Pfoh, Rebecca Schulte, Phuc Le, Michael B Rothberg
No abstract text is available yet for this article.
April 24, 2024: Obesity
https://read.qxmd.com/read/38659125/response-to-early-and-later-stage-persistence-with-antiobesity-medications-a-retrospective-cohort-study
#27
LETTER
Angela Fitch, Amber Huett-Garcia
No abstract text is available yet for this article.
April 24, 2024: Obesity
https://read.qxmd.com/read/38653583/hedonic-hunger-eating-behavior-and-food-reward-and-preferences-1-year-after-initial-weight-loss-by-diet-or-bariatric-surgery
#28
JOURNAL ARTICLE
Marthe Isaksen Aukan, Graham Finlayson, Catia Martins
OBJECTIVE: The objective of this study was to investigate changes in hedonic hunger, eating behavior, and food reward and preferences at 1-year (1Y) follow-up after an initial weight loss (WL) induced by a 10-week, very low-energy diet alone (controls) or in combination with bariatric surgery. METHODS: Patients scheduled for sleeve gastrectomy or Roux-en-Y gastric bypass and controls were recruited. Body weight/composition, hedonic hunger (Power of Food Scale), eating behavior traits (Dutch Eating Behavior Questionnaire and Three-Factor Eating Questionnaire), and food reward and preferences (computerized behavioral task) were measured at baseline, 11 weeks, and 1Y follow-up...
April 23, 2024: Obesity
https://read.qxmd.com/read/38644683/physiology-of-the-weight-loss-plateau-in-response-to-diet-restriction-glp-1-receptor-agonism-and-bariatric-surgery
#29
JOURNAL ARTICLE
Kevin D Hall
OBJECTIVE: The objective of this study was to investigate why different weight-loss interventions result in varying durations of weight loss prior to approaching plateaus. METHODS: A validated mathematical model of energy metabolism and body composition dynamics was used to simulate mean weight- and fat-loss trajectories in response to diet restriction, semaglutide 2.4 mg, tirzepatide 10 mg, and Roux-en-Y gastric bypass (RYGB) surgery interventions...
April 22, 2024: Obesity
https://read.qxmd.com/read/38644654/maternal-obesity-sex-specific-in-utero-changes-in-fetal-brain-autophagy-and-mtor
#30
JOURNAL ARTICLE
Nana Merabova, Lierni Ugartemendia, Andrea G Edlow, Claudia Ibarra, Nune Darbinian, Gabriel Tatevosian, Laura Goetzl
OBJECTIVE: Maternal obesity affects 39.7% of reproductive-age women in the United States. Emerging research has suggested that in utero exposure to maternal obesity is associated with adverse neurodevelopmental outcomes, but knowledge of underlying mechanisms in human samples is lacking. METHODS: A matched case-control study was performed in women with singleton fetuses who were undergoing elective pregnancy termination at gestational ages 15 to 21 weeks...
April 21, 2024: Obesity
https://read.qxmd.com/read/38627016/effect-of-a-low-carbohydrate-diet-on-pain-and-quality-of-life-in-female-patients-with-lipedema-a-randomized-controlled-trial
#31
JOURNAL ARTICLE
Julianne Lundanes, Frida Sandnes, Kari Hanne Gjeilo, Patrik Hansson, Sissel Salater, Catia Martins, Siren Nymo
OBJECTIVE: The primary objective of this study was to evaluate the effect of a low-carbohydrate diet (LCD) compared with a control diet on pain in female patients with lipedema. The secondary objectives were to compare the impact of the two diets on quality of life (QoL) and investigate potential associations of changes in pain with changes in body weight, body composition, and ketosis. METHODS: Adult female patients with lipedema and obesity were randomized to either the LCD or control diet (energy prescription: 1200 kcal/day) for 8 weeks...
April 16, 2024: Obesity
https://read.qxmd.com/read/38616328/interindividual-differences-of-dietary-fat-inducible-mest-in-white-adipose-tissue-of-c57bl-6j-mice-are-not-heritable
#32
JOURNAL ARTICLE
Rea Victoria P Anunciado-Koza, Haifeng Yin, Crystal L Bilodeau, Diana Cooke, Gene P Ables, Sergey Ryzhov, Robert A Koza
OBJECTIVE: Differences in white adipose tissue (WAT) expression of mesoderm-specific transcript (Mest) in C57BL6/J mice fed a high-fat diet (HFD) are concomitant with and predictive for the development of obesity. However, the basis for differences in WAT Mest among mice is unknown. This study investigated whether HFD-inducible WAT Mest, as well as susceptibility to obesity, is transmissible from parents to offspring. METHODS: WAT biopsies of mice fed an HFD for 2 weeks identified parents with low and high WAT Mest for breeding...
April 14, 2024: Obesity
https://read.qxmd.com/read/38600047/impact-of-sustained-calorie-restriction-and-weight-cycling-on-body-composition-in-high-fat-diet-fed-male-and-female-c57bl-6j-mice
#33
JOURNAL ARTICLE
Daniel L Smith, Yongbin Yang, Luis M Mestre, Beate Henschel, Erik Parker, Stephanie Dickinson, Amit Patki, David B Allison, Tim R Nagy
OBJECTIVE: The objective of this study was to investigate body composition changes with weight cycling (WC) among adult C57BL/6J mice with diet-induced obesity. METHODS: A total of 555 single-housed mice were fed a high-fat diet ad libitum (AL) from 8 to 43 weeks of age. The 200 heaviest mice of each sex were randomized to the following four groups: ever obese (EO, continued AL feeding); obese weight loser (OWL, calorie-restricted); obese weight loser moderate (OWLM, body weight halfway between EO and OWL); and WC (diet restricted to OWL followed by AL refeeding cycles)...
April 10, 2024: Obesity
https://read.qxmd.com/read/38575355/correction-to-predictors-of-racial-differences-in-weight-loss-the-propel-trial
#34
(no author information available yet)
No abstract text is available yet for this article.
April 4, 2024: Obesity
https://read.qxmd.com/read/38575197/adipocyte-derived-inflammatory-molecules-induce-senescent-b-cells-through-metabolic-pathways
#35
JOURNAL ARTICLE
Daniela Frasca, Maria Romero, Denisse Garcia, Seth Thaller, Valquiria Bueno
OBJECTIVE: The aim of this study was to demonstrate that an adipocyte tissue-derived conditioned medium (ACM) contains inflammatory molecules that induce senescence in B cells. METHODS: We incubated blood-derived B cells from lean donors with ACM obtained from the adipose tissue of adult female donors with obesity undergoing weight reduction surgery or with medium as control. After 24 h, cells were harvested, and the expression of transcripts for proinflammatory cytokines (TNF/IL-6), chemokines (IL-8), and for markers of the senescence-associated secretory phenotype (SASP) was measured by quantitative polymerase chain reaction...
April 4, 2024: Obesity
https://read.qxmd.com/read/38572577/maternal-folic-acid-supplementation-during-pregnancy-in-association-with-childhood-overweight-or-obesity
#36
JOURNAL ARTICLE
Chi-Yen Hung, Hsin-Ju Lee, Zhao-Ting Tsai, Shu-Jung Huang, Hsin-Yi Huang, Hui-Ju Tsai, Tsung-Chieh Yao
OBJECTIVE: This study aimed to examine associations of maternal folic acid supplementation (FAS) during pregnancy with childhood overweight or obesity (OWO) or adiposity. METHODS: In a population-based cohort of 1479 children, maternal FAS during pregnancy was assessed retrospectively by questionnaires. BMI and body fat percentages were measured at a mean age of 6.4 years. Pertinent factors were accounted for in data analyses. RESULTS: Maternal FAS during pregnancy was negatively associated with OWO (adjusted odds ratio: 0...
April 4, 2024: Obesity
https://read.qxmd.com/read/38558513/repeated-photodynamic-therapy-using-a-chlorin-e6-embedded-device-to-prolong-the-therapeutic-effects-on-obesity
#37
JOURNAL ARTICLE
Jung-Hoon Park, Ji Won Kim, Dae Sung Ryu, Hyeonseung Lee, Hee Kyong Na, Jin Hee Noh, Do Hoon Kim, Sanghee Lee, Kun Na, Hwoon-Yong Jung
OBJECTIVE: This study aimed to investigate the efficacy and safety of repeated photodynamic therapy (PDT) with a chlorin e6 (Ce6)-embedded intragastric satiety-inducing device (ISD) to maintain therapeutic effects of obesity in a juvenile pig. METHODS: The Ce6-embedded ISD was fabricated with a dipping method. Twelve pigs were divided into four groups of three and were administered control, single, biweekly, or weekly PDT, respectively. The therapeutic effects were assessed by comparing the results of phototoxicity, endoscopy, fluoroscopy, hormone and weight changes, and histological examination...
April 1, 2024: Obesity
https://read.qxmd.com/read/38515392/exposure-to-4-4-dde-in-visceral-adipose-tissue-and-weight-loss-in-adolescents-from-the-teen-labs-cohort
#38
JOURNAL ARTICLE
Bruna Rubbo, Zhenjiang Li, Phum Tachachartvanich, Brittney O Baumert, Hongxu Wang, Shudi Pan, Sarah Rock, Justin R Ryder, Todd Jenkins, Stephanie Sisley, Xiangping Lin, Scott Bartell, Thomas H Inge, Stavra Xanthakos, Brooklynn McNeil, Anna R Robuck, Michele A La Merrill, Douglas I Walker, David V Conti, Rob McConnell, Sandrah P Eckel, Lida Chatzi
OBJECTIVE: Dichlorodiphenyldichloroethylene (DDE), an obesogen accumulating in adipose tissue, is released into circulation with weight loss, although its impact is underexplored among adolescents. We tested the association using an integrative translational approach of epidemiological analysis among adolescents with obesity and in vitro measures exploring the impact of DDE on adipogenesis via preadipocytes. METHODS: We included 63 participants from the Teen-Longitudinal Assessment of Bariatric Surgery (Teen-LABS) cohort...
March 22, 2024: Obesity
https://read.qxmd.com/read/38803313/unraveling-the-roles-of-ectopic-adipose-depots-and-physical-activity-in-age-related-mitochondrial-decline
#39
JOURNAL ARTICLE
Brian A Irving, Hawley E Kunz
No abstract text is available yet for this article.
June 2024: Obesity
https://read.qxmd.com/read/38803308/associations-between-regional-adipose-tissue-distribution-and-skeletal-muscle-bioenergetics-in-older-men-and-women
#40
JOURNAL ARTICLE
Andrea M Brennan, Paul M Coen, Theresa Mau, Megan Hetherington-Rauth, Frederico G S Toledo, Erin E Kershaw, Peggy M Cawthon, Philip A Kramer, Sofhia V Ramos, Anne B Newman, Steven R Cummings, Daniel E Forman, Reichelle X Yeo, Giovanna Distefano, Iva Miljkovic, Jamie N Justice, Anthony J A Molina, Michael J Jurczak, Lauren M Sparks, Stephen B Kritchevsky, Bret H Goodpaster
OBJECTIVE: The aim of this study was to examine associations of ectopic adipose tissue (AT) with skeletal muscle (SM) mitochondrial bioenergetics in older adults. METHODS: Cross-sectional data from 829 adults ≥70 years of age were used. Abdominal, subcutaneous, and visceral AT and thigh muscle fat infiltration (MFI) were quantified by magnetic resonance imaging. SM mitochondrial energetics were characterized in vivo (31 P-magnetic resonance spectroscopy; ATPmax ) and ex vivo (high-resolution respirometry maximal oxidative phosphorylation [OXPHOS])...
June 2024: Obesity
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