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Clinical Research in Cardiology : Official Journal of the German Cardiac Society

https://read.qxmd.com/read/38407585/prognostic-implication-of-heart-failure-stage-and-left-ventricular-ejection-fraction-for-patients-with-in-hospital-cardiac-arrest-a-16-year-retrospective-cohort-study
#1
JOURNAL ARTICLE
Chih-Hung Wang, Li-Ting Ho, Meng-Che Wu, Cheng-Yi Wu, Joyce Tay, Pei-I Su, Min-Shan Tsai, Yen-Wen Wu, Wei-Tien Chang, Chien-Hua Huang, Wen-Jone Chen
BACKGROUND: The 2022 AHA/ACC/HFSA guidelines for the management of heart failure (HF) makes therapeutic recommendations based on HF status. We investigated whether the prognosis of in-hospital cardiac arrest (IHCA) could be stratified by HF stage and left ventricular ejection fraction (LVEF). METHODS: This single-center retrospective study analyzed the data of patients who experienced IHCA between 2005 and 2020. Based on admission diagnosis, past medical records, and pre-arrest echocardiography, patients were classified into general IHCA, at-risk for HF, pre-HF, HF with preserved ejection fraction (HFpEF), and HF with mildly reduced ejection fraction or HF with reduced ejection fraction (HFmrEF-or-HFrEF) groups...
February 26, 2024: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://read.qxmd.com/read/38407584/causal-association-between-lipoproteins-and-risk-of-coronary-artery-disease-a-systematic-review-and-meta-analysis-of-mendelian-randomization-studies
#2
REVIEW
Rongyuan Yang, Shirong Wu, Zhen Zhao, Xuanxuan Deng, Qiuying Deng, Dawei Wang, Qing Liu
OBJECTIVE: To systematically evaluate the causal effect of lipoproteins to the risk of coronary artery disease (CAD) by systematic review and meta-analysis of the associated Mendelian randomization (MR) studies. METHODS: This systematic review was registered in PROSPERO (ID CRD42023465430). Searches from the databases (e.g., PubMed, Embase, Cochrane, Web of Science) and non-database sources to collect MR studies. The search time frame was from the database inception to August 2023...
February 26, 2024: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://read.qxmd.com/read/38407583/90-jahrestagung-der-deutsche-gesellschaft-f%C3%A3-r-kardiologie-herz-und-kreislaufforschung-e-v-german-cardiac-society-03-06-april-2024%C3%A2-congress-center-rosengarten-mannheim
#3
(no author information available yet)
No abstract text is available yet for this article.
February 26, 2024: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://read.qxmd.com/read/38407582/human-nerve-distribution-and-density-around-the-carotid-artery-bifurcation
#4
LETTER
Helge Struthoff, Lucas Lauder, Jan M Federspiel, Mathias Hohl, Michael Böhm, Thomas Tschernig, Felix Mahfoud
No abstract text is available yet for this article.
February 26, 2024: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://read.qxmd.com/read/38381365/publisher-correction-respiratory-exchange-ratio-overshoot-during-exercise-recovery-a-promising-prognostic-marker-in-hfref
#5
Marco Vecchiato, Daniel Neunhaeuserer, Emanuele Zanardo, Giulia Quinto, Francesca Battista, Andrea Aghi, Stefano Palermi, Luciano Babuin, Chiara Tessari, Marco Guazzi, Andrea Gasperetti, Andrea Ermolao
No abstract text is available yet for this article.
February 21, 2024: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://read.qxmd.com/read/38381364/how-does-electrocardiography-derived-compare-with-angiography-derived-coronary-microcirculatory-resistance-index-in-patients-with-takotsubo-syndrome
#6
LETTER
John E Madias
No abstract text is available yet for this article.
February 21, 2024: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://read.qxmd.com/read/38372753/use-of-class-ic-antiarrhythmic-drugs-in-patients-with-structural-heart-disease-and-implantable-cardioverter-defibrillator
#7
JOURNAL ARTICLE
Maura M Zylla, Julian Wolfes, Ruben Schleberger, Dennis Lawin, Meinhard Kieser, Florian Reinke, Lars Eckardt, Andreas Rillig, Christoph Stellbrink, Dierk Thomas, Norbert Frey, Patrick Lugenbiel
BACKGROUND: Due to suspected pro-arrhythmic effects and increased mortality associated with class-IC antiarrhythmic drugs (AADs) in previous trials, AAD therapy in structural heart disease (SHD) is mainly restricted to amiodarone. In the presence of diagnostic and therapeutic advancements in cardiovascular medicine, it remains unclear if previous studies adequately reflect contemporary patients. In clinical practice, class-IC-AADs are occasionally used in individual cases, particularly in patients with an implantable cardioverter defibrillator (ICD)...
February 19, 2024: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://read.qxmd.com/read/38358420/comparison-of-arctic-front-advance-pro-and-polarx-cryoballoons-for-ablation-therapy-of-atrial-fibrillation-an-intraprocedural-analysis
#8
JOURNAL ARTICLE
Vincent Knappe, Caroline Lahrmann, Maximilian Funken, Andreas Zietzer, Christopher Gestrich, Georg Nickenig, Jan W Schrickel, Thomas Beiert
INTRODUCTION: Cryoballoon (CB) ablation has become a popular method for pulmonary vein isolation (PVI) in atrial fibrillation (AF) treatment. This study aimed to compare the intraprocedural ablation characteristics of two cryoballoons, Arctic Front Advance Pro™ (AFA-Pro, Medtronic) and POLARx™ (Boston Scientific). METHODS AND RESULTS: In this retrospective single-center study, 230 symptomatic paroxysmal or persistent AF patients underwent CB ablation with either AFA-Pro or POLARx...
February 15, 2024: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://read.qxmd.com/read/38358419/incidence-and-clinical-impact-of-renal-failure-and-bleeding-following-transcatheter-tricuspid-valve-annuloplasty
#9
JOURNAL ARTICLE
Thorsten Gietzen, Jan Althoff, Laurin Ochs, Muhammed Gerçek, Jennifer von Stein, Caroline Hasse, Christos Iliadis, Kai Friedrichs, Volker Rudolph, Stephan Baldus, Roman Pfister, Maria Isabel Körber
BACKGROUND: Bleeding is the most common complication after percutaneous leaflet-based tricuspid valve repair and associated with acute kidney injury (AKI) and adverse outcome. TTVA with the Cardioband system is a technically more complex procedure; however, frequency and prognostic impact of postinterventional bleeding and renal complications have not been thoroughly examined. AIMS: This study was performed to determine the incidence and clinical impact of bleeding complications (MVARC criteria) and acute kidney injury (KDIGO criteria) following transcatheter tricuspid valve annuloplasty (TTVA)...
February 15, 2024: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://read.qxmd.com/read/38358418/frailty-periinterventional-complications-and-outcome-in-patients-undergoing-percutaneous-mitral-and-tricuspid-valve-repair
#10
JOURNAL ARTICLE
Matthieu Schäfer, Hannah Nöth, Clemens Metze, Christos Iliadis, Maria Isabel Körber, Marcel Halbach, Stephan Baldus, Roman Pfister
BACKGROUND: Frailty is common in elderly and multimorbid patients and associated with increased vulnerability to stressors. METHODS: In a single centre study frailty according to Fried criteria was assessed in consecutive patients before transcatheter mitral and tricuspid valve repair. Postprocedural infections, blood transfusion and bleeding and renal failure were retrospectively assessed from records. Median follow-up time for survival was 560 days (IQR: 363 to 730 days)...
February 15, 2024: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://read.qxmd.com/read/38358417/respiratory-exchange-ratio-overshoot-during-exercise-recovery-a-promising-prognostic-marker-in-hfref
#11
JOURNAL ARTICLE
Marco Vecchiato, Daniel Neunhaeuserer, Emanuele Zanardo, Giulia Quinto, Francesca Battista, Andrea Aghi, Stefano Palermi, Luciano Babuin, Chiara Tessari, Marco Guazzi, Andrea Gasperetti, Andrea Ermolao
BACKGROUND AND AIMS: Transient increases (overshoot) in respiratory gas analyses have been observed during exercise recovery, but their clinical significance is not clearly understood. An overshoot phenomenon of the respiratory exchange ratio (RER) is commonly observed during recovery from maximal cardiopulmonary exercise testing (CPET), but it has been found reduced in patients with heart failure with reduced ejection fraction (HFrEF). The aim of the study was to analyze the clinical significance of these RER recovery parameters and to understand if these may improve the risk stratification of patients with HFrEF...
February 15, 2024: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://read.qxmd.com/read/38358416/efficacy-of-dapagliflozin-in-improving-arrhythmia-related-outcomes-after-ablation-for-atrial-fibrillation-a-retrospective-single-center-study
#12
JOURNAL ARTICLE
Hyeong Jun Noh, Sung Joo Cha, Chee Hae Kim, Suk-Won Choi, Chang Hoon Lee, Jin Kyung Hwang
BACKGROUND: Atrial fibrillation (AF) is a widespread type of sustained arrhythmia that poses significant health risks. Catheter ablation is the preferred treatment; however, arrhythmia recurrence remains challenging. Sodium-glucose co-transporter 2 inhibitors, particularly dapagliflozin (DAPA), have exhibited cardiovascular benefits. However, to date, the influence of these inhibitors on AF post-ablation remains unclear. METHODS: We analyzed the records of 272 patients who underwent catheter ablation for AF from January 2018 to December 2022...
February 15, 2024: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://read.qxmd.com/read/38358415/clinical-and-serological-characterization-of-acute-pleuropericarditis-suggests-an-autoinflammatory-pathogenesis-and-highlights-risk-factors-for-recurrent-attacks
#13
JOURNAL ARTICLE
Dorothee Kaudewitz, Lukas John, Jan Meis, Norbert Frey, Hanns-Martin Lorenz, Florian Leuschner, Norbert Blank
PURPOSE: We describe the manifestations and course of patients with pleuropericarditis (PP). Serum parameters were analyzed to evaluate the contribution of autoimmune and autoinflammatory mechanisms to PP pathogenesis. Finally, we outline risk factors for recurrent PP attacks. METHODS: Electronic medical records of the University Hospital Heidelberg were screened for PP diagnosis between the years 2009 and 2021. A total of 164 patients were detected and compared to patients suffering from systemic lupus erythematosus (SLE)-associated PP...
February 15, 2024: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://read.qxmd.com/read/38353684/sodium-glucose-cotransporter-2-inhibitors-with-cardiac-arrhythmias-in-patients-with-type-2-diabetes-mellitus-a-systematic-review-and-meta-analysis-of-randomized-placebo-controlled-trials
#14
JOURNAL ARTICLE
Bo Xu, Bo Kang, Jiecan Zhou
BACKGROUND: Type 2 diabetes mellitus (T2DM) is associated with an increased risk of cardiac arrhythmias, which increases serious morbidity and mortality. Novel hypoglycemic drug sodium glucose cotransporter 2 (SGLT2) inhibitor has shown sufficient cardiovascular benefits in cardiovascular outcome trials. OBJECTIVE: This systematic review and meta-analysis aimed to investigate the relationship between SGLT2 inhibitors and cardiac arrhythmias in patients with T2DM...
February 14, 2024: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://read.qxmd.com/read/38353683/cost-effectiveness-of-a-multidimensional-post-discharge-disease-management-program-for-heart-failure-patients-economic-evaluation-along-a-one-year-observation-period
#15
JOURNAL ARTICLE
T Egelseer-Bruendl, B Jahn, M Arvandi, S Puntscher, J Santamaria, L Brunelli, K Weissenegger, B Pfeifer, S Neururer, C Rissbacher, A Huber, B Fetz, C Kleinheinz, R Modre-Osprian, K Kreiner, U Siebert, G Poelzl
OBJECTIVE: This study aimed to assess the cost-effectiveness of the telemedically assisted post-discharge management program (DMP) HerzMobil Tirol (HMT) for heart failure (HF) patients in clinical practice in Austria. METHODS: We conducted a cost-effectiveness analysis along a retrospective cohort study (2016-2019) of HMT with a propensity score matched cohort of 251 individuals in the HMT and 257 in the usual care (UC) group and a 1-year follow-up. We calculated the effectiveness (hospital-free survival, hospital-free life-years gained, and number of avoided rehospitalizations), costs (HMT, rehospitalizations), and the incremental cost-effectiveness ratio (ICER)...
February 14, 2024: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://read.qxmd.com/read/38353682/relevance-of-mexiletine-in-the-era-of-evolving-antiarrhythmic-therapy-of-ventricular-arrhythmias
#16
REVIEW
Nawar Alhourani, Julian Wolfes, Hilke Könemann, Christian Ellermann, Gerrit Frommeyer, Fatih Güner, Philipp Sebastian Lange, Florian Reinke, Julia Köbe, Lars Eckardt
Despite impressive developments in the field of ventricular arrhythmias, there is still a relevant number of patients with ventricular arrhythmias who require antiarrhythmic drug therapy and may, e.g., in otherwise drug and/or ablation refractory situations, benefit from agents known for decades, such as mexiletine. Through its capability of blocking fast sodium channels in cardiomyocytes, it has played a minor to moderate antiarrhythmic role throughout the recent decades. Nevertheless, certain patients with structural heart disease suffering from drug-refractory, i...
February 14, 2024: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://read.qxmd.com/read/38353681/sex-related-differences-in-patients-presenting-with-heart-failure-related-cardiogenic-shock
#17
JOURNAL ARTICLE
Jonas Sundermeyer, Caroline Kellner, Benedikt N Beer, Lisa Besch, Angela Dettling, Letizia Fausta Bertoldi, Stefan Blankenberg, Jeroen Dauw, Zouhir Dindane, Dennis Eckner, Ingo Eitel, Tobias Graf, Patrick Horn, Joanna Jozwiak-Nozdrzykowska, Paulus Kirchhof, Stefan Kluge, Axel Linke, Ulf Landmesser, Peter Luedike, Enzo Lüsebrink, Nicolas Majunke, Norman Mangner, Octavian Maniuc, Sven Möbius-Winkler, Peter Nordbeck, Martin Orban, Federico Pappalardo, Matthias Pauschinger, Michal Pazdernik, Alastair Proudfoot, Matthew Kelham, Tienush Rassaf, Clemens Scherer, Paul Christian Schulze, Robert H G Schwinger, Carsten Skurk, Marek Sramko, Guido Tavazzi, Holger Thiele, Luca Villanova, Nuccia Morici, Ephraim B Winzer, Dirk Westermann, Benedikt Schrage
BACKGROUND: Heart failure-related cardiogenic shock (HF-CS) accounts for a significant proportion of all CS cases. Nevertheless, there is a lack of evidence on sex-related differences in HF-CS, especially regarding use of treatment and mortality risk in women vs. men. This study aimed to investigate potential differences in clinical presentation, use of treatments, and mortality between women and men with HF-CS. METHODS: In this international observational study, patients with HF-CS (without acute myocardial infarction) from 16 tertiary-care centers in five countries were enrolled between 2010 and 2021...
February 14, 2024: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://read.qxmd.com/read/38353680/valve-unit-instead-of-intensive-or-intermediate-care-unit-admission-following-transcatheter-edge-to-edge-mitral-valve-repair-is-safe-and-reduces-postprocedural-complications
#18
JOURNAL ARTICLE
Matthias Gröger, Dominik Felbel, Michael Paukovitsch, Leonhard Moritz Schneider, Sinisa Markovic, Wolfgang Rottbauer, Mirjam Keßler
BACKGROUND: Transcatheter edge-to-edge mitral valve repair (M-TEER) is often performed in general anesthesia, and postprocedural monitoring is usually warranted on an intensive or intermediate care unit (ICU/IMC). We evaluated the implications of a dedicated valve unit (VU) instead of an ICU/IMC for monitoring after M-TEER. METHODS AND RESULTS: In total, 624 patients were retrospectively analyzed. A total of 312 patients were primarily transferred to either ICU or IMC following M-TEER, and 312 patients were scheduled for the VU in the absence of indications for ICU/IMC treatment...
February 14, 2024: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://read.qxmd.com/read/38342792/correction-to-the-zwolle-experience-with-left-bundle-branch-area-pacing-using-stylet-driven-active-fixation-leads
#19
F Daniëls, A Adiyaman, K M Aarnink, F J Oosterwerff, J R A Verbakel, A Ghani, J J J Smit, M A Kanters, P P H M Delnoy, A Elvan
No abstract text is available yet for this article.
February 12, 2024: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://read.qxmd.com/read/38329513/a-novel-score-to-predict-in-hospital-mortality-for-patients-with-acute-coronary-syndrome-and-out-of-hospital-cardiac-arrest-the-factor-study
#20
JOURNAL ARTICLE
Victor Schweiger, Pauline Hiller, Rahel Utters, Angela Fenice, Victoria Lucia Cammann, Davide Di Vece, Katja Rajman, Alessandro Candreva, Alexander Gotschy, Thomas Gilhofer, Michael Würdinger, Barbara E Stähli, Burkhardt Seifert, Stefan M Müller, Christian Templin, Julia Stehli
INTRODUCTION: Acute coronary syndromes (ACS) represent a substantial global healthcare challenge. In its most severe form, it can lead to out-of-hospital cardiac arrest (OHCA). Despite medical advancements, survival rates in OHCA patients remain low. Further, the prediction of outcomes in these patients poses a challenge to all health care providers involved. This study aims at developing a score with variables available on admission to assess in-hospital mortality of patients with OHCA undergoing coronary angiography...
February 8, 2024: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
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