Andrea Rognoni, Lucia Barbieri, Chiara Cavallino, Sara Bacchini, Alessia Veia, Anna Degiovanni, Francesco Rametta, Federico Nardi, Maurizio Lazzero, Alessandro Lupi, Angelo S Bongo
Coronary artery disease is the major cause of mortality and morbidity in the industrialized countries; in the United States of America and in Europe, it is responsible for one of every six deaths per year. In the setting of ischemic heart disease, angina pectoris and chest pain, in particular, are the major causes of emergency department accesses. Angina pectoris is a clinical syndrome characterized by discomfort typically in the chest, neck, chin and left arm induced by physical exertion, emotional stress and cold and is relieved by rest or by taking of nitrates...
December 2013: Recent Patents on Cardiovascular Drug Discovery