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Internal and Emergency Medicine

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https://read.qxmd.com/read/30771083/hypocalcemia-and-hypophosphatemia-after-treatment-with-zoledronic-acid-in-a-patient-with-al-amyloidosis
#1
Antonella Tufano, Domenico Rendina, Paolo Conca, Beniamino Matani, Giovanni Di Minno
No abstract text is available yet for this article.
February 15, 2019: Internal and Emergency Medicine
https://read.qxmd.com/read/30767158/assessing-the-lung-cancer-risk-reduction-potential-of-candidate-modified-risk-tobacco-products
#2
Julia Hoeng, Serge Maeder, Patrick Vanscheeuwijck, Manuel C Peitsch
Smoking is the major cause of lung cancer. While the risk of lung cancer increases with the number of cigarettes smoked and the duration of smoking, it also decreases upon smoking cessation. The development of candidate modified risk tobacco products (cMRTP) is aimed at providing smokers who will not quit with alternatives to cigarettes that present less risk of harm and smoking-related disease. It is necessary to assess the risk reduction potential of cMRTPs, including their potential to reduce the risk of lung cancer...
February 14, 2019: Internal and Emergency Medicine
https://read.qxmd.com/read/30747364/nephrotic-range-proteinuria-and-acute-heart-failure
#3
Matteo Landolfo, Giulia Fiorini, Claudio Borghi
No abstract text is available yet for this article.
February 12, 2019: Internal and Emergency Medicine
https://read.qxmd.com/read/30747363/a-29-year-old-woman-with-persistent-thrombocytopenia
#4
Irene Di Pasquale, Antonella Bertomoro, Fabrizio Vianello, Piero Marson, Francesca Boscaro, Fabrizio Fabris
No abstract text is available yet for this article.
February 12, 2019: Internal and Emergency Medicine
https://read.qxmd.com/read/30747365/phenotypes-in-beh%C3%A3-et-s-syndrome
#5
REVIEW
Emire Seyahi
Behçet syndrome (BS) is a multi-systemic complex disorder with unknown etiology and a unique geographic distribution. It could not be possible to include it into specific classification schemes and it is certainly not a uniform disease. Several cluster and association studies revealed that it has been composed of multiple phenotypes ascribing the principal problem such as skin-mucosa, joint, eye, vascular, neurological and gastrointestinal involvement. Each phenotype has its own characteristic demographic and clinical features as such their management strategies and prognosis differ substantially...
February 11, 2019: Internal and Emergency Medicine
https://read.qxmd.com/read/30737726/risk-factors-for-extended-spectrum-beta-lactamase-producing-enterobacteriales-infection-are-they-the-same-in-neutropenic-and-non-neutropenic-patients
#6
Filippo Lagi, Giampaolo Corti
No abstract text is available yet for this article.
February 8, 2019: Internal and Emergency Medicine
https://read.qxmd.com/read/30737725/pathergy-testing-prospective-comparison-of-dermatoscopic-evaluation-and-naked-eye-examination
#7
Aysegul Sevim Kecici, Zekayi Kutlubay, Server Serdaroglu, Yalcin Tuzun
Pathergy phenomenon is a non-specific tissue hyperreactivity reaction due to trauma and is a minor diagnostic criterion of Behcet's disease. In this study, 100 patients with a suspicion of Behcet's disease who were referred to Cerrahpasa Medical Faculty Dermatology department between 01.11.2014 and 31.01.2015 are included. Skin pathergy tests were applied to all the patients and results were evaluated by two dermatologists separately at 48th hour, each with naked eye and with dermatoscopy. Test results were scored on a scale of 0-6...
February 8, 2019: Internal and Emergency Medicine
https://read.qxmd.com/read/30730033/five-steps-for-the-use-and-interpretation-of-d-dimer-in-the-emergency-department
#8
Elisa Gesu, Anna Maria Rusconi, Elisa Ceriani
No abstract text is available yet for this article.
February 7, 2019: Internal and Emergency Medicine
https://read.qxmd.com/read/30729384/sepsis-patients-with-complication-of-hypoglycemia-and-hypoalbuminemia-are-an-early-and-easy-identification-of-high-mortality-risk
#9
Makoto Furukawa, Kosaku Kinoshita, Junko Yamaguchi, Satoshi Hori, Atsushi Sakurai
Either hypoglycemia or hypoalbuminemia alone is an independent condition associated with increased risk of mortality in critical illness. This study evaluates whether the mortality risk increases in septic patients if these conditions are combined. Patients admitted to our hospital from 2008 to 2015 who satisfied the definition of sepsis were targeted (n = 336). We classified cases into three groups based on blood glucose (BG) level measured at admission: hypoglycemia (Hypo-G; BG < 80 mg/dl), intermediate glycemia (Inter-G; 80-199 mg/dl), and hyperglycemia (Hyper-G; ≥ 200 mg/dl) group, and then estimated mortality...
February 7, 2019: Internal and Emergency Medicine
https://read.qxmd.com/read/30725323/quick-sequential-organ-failure-assessment-as-a-prognostic-factor-for-infected-patients-outside-the-intensive-care-unit-a-systematic-review-and-meta-analysis
#10
REVIEW
Yan-Cun Liu, Yuan-Yuan Luo, Xingyu Zhang, Song-Tao Shou, Yu-Lei Gao, Bin Lu, Chen Li, Yan-Fen Chai
Quick Sequential Organ Failure Assessment (qSOFA) was proposed to replace SIRS as a new screening tool for the identification of septic patients at high mortality. However, researches from infected patients outside of ICU especially in Emergency Department (ED) drew contradictory conclusions on the prognostic value of qSOFA. This systematic review evaluated qSOFA as a prognostic marker of infected patients outside of ICU. The primary outcome was hospital mortality or 28- or 30-day mortality. Data were pooled based on sensitivity and specificity...
February 6, 2019: Internal and Emergency Medicine
https://read.qxmd.com/read/30721398/iron-replacement-in-inflammatory-bowel-diseases-an-evolving-scenario
#11
Fabiana Busti, Giacomo Marchi, Domenico Girelli
No abstract text is available yet for this article.
February 5, 2019: Internal and Emergency Medicine
https://read.qxmd.com/read/30712149/assessment-of-deep-venous-thrombosis-in-the-lower-extremity-in-beh%C3%A3-et-s-syndrome-mr-venography-versus-doppler-ultrasonography
#12
Burcin Tutar, Fatih Kantarci, Osman Serdal Cakmak, Hasan Yazici, Emire Seyahi
Lower extremity venous thrombosis (DVT) is the most common vascular manifestation of Behçet's syndrome (BS). Currently, Doppler ultrasonography (USG) is the most commonly preferred imaging modality in the diagnosis and follow-up of patients with acute and chronic DVT. Magnetic resonance (MR) venography, a quick and a non-invasive imaging modality, is successfully used to detect DVT in various settings. We had been unaware of studies with MR venography in BS. The aim of this study is to compare the diagnostic value of true fast imaging with steady-state precession magnetic resonance (True-FISP MR) venography and Doppler USG in the assessment of chronic DVT among patients with BS...
February 2, 2019: Internal and Emergency Medicine
https://read.qxmd.com/read/30712148/a-randomised-open-label-cross-over-clinical-study-to-evaluate-the-pharmacokinetic-profiles-of-cigarettes-and-e-cigarettes-with-nicotine-salt-formulations-in-us-adult-smokers
#13
Grant O'Connell, John D Pritchard, Chris Prue, Joseph Thompson, Thomas Verron, Donald Graff, Tanvir Walele
E-cigarettes containing 'nicotine salts' aim to increase smoker's satisfaction by improving blood nicotine delivery and other sensory properties. Here, we evaluated the pharmacokinetic profiles and subjective effects of nicotine from two e-cigarette device platforms with varying concentrations of nicotine lactate (nicotine salt) e-liquid relative to conventional cigarettes. A randomised, open-label, cross-over clinical study was conducted in 15 healthy US adult smokers. Five different e-cigarette products were evaluated consecutively on different days after use of own brand conventional cigarette...
February 2, 2019: Internal and Emergency Medicine
https://read.qxmd.com/read/30706253/associated-vitamin-d-deficiency-is-a-risk-factor-for-the-complication-of-hcv-related-liver-cirrhosis-including-hepatic-encephalopathy-and-spontaneous-bacterial-peritonitis
#14
Monkez Moteih Yousif, Ayman Magd Eldin Mohammad Sadek, Hesham Ahmad Farrag, Fayrouz Othman Selim, Emad Fawzi Hamed, Rasha Ibrahim Salama
The influence of vitamin D, 25-hydroxyvitamin D (25(OH)D), deficiency on hepatitis C virus (HCV)-related cirrhosis had been poorly elucidated especially in patients with hepatic encephalopathy (HE) and spontaneous bacterial peritonitis (SBP). We aimed to investigate the association between vitamin D deficiency and the risk of SBP or HE, including the mortality rate. Serum 25(OH)D levels were prospectively determined in 135 patients. Of them, 45 patients had complications with HE and 45 patients had complications with SBP; 45 cirrhotic patients without complication served as the control group...
January 31, 2019: Internal and Emergency Medicine
https://read.qxmd.com/read/30706252/step-down-units-are-cost-effective-alternatives-to-coronary-care-units-with-non-inferior-outcomes-in-the-management-of-st-elevation-myocardial-infarction-patients-after-successful-primary-percutaneous-coronary-intervention
#15
Yu-Shao Chou, Hsin-Yueh Lin, Yi-Ming Weng, Zhong Ning Leonard Goh, Cheng-Yu Chien, Hsuan-Jui Fan, Chih-Huang Li, Hsien-Yi Chen, Ming-Shun Hsieh, Joanna Chen-Yeen Seak, Chen-Ken Seak, Chen-June Seak
Percutaneous coronary interventions (PCIs) within a door-to-balloon timing of 90 min have greatly decreased mortality and morbidity of ST-elevation myocardial infarction (STEMI) patients. Post-PCI, they are routinely transferred into the coronary care unit (CCU) regardless of the severity of their condition, resulting in frequent CCU overcrowding. This study assesses the feasibility of step-down units (SDUs) as an alternative to CCUs in the management of STEMI patients after successful PCI, to alleviate CCU overcrowding...
January 31, 2019: Internal and Emergency Medicine
https://read.qxmd.com/read/30694436/elder-abuse-perception-and-knowledge-of-the-phenomenon-by-healthcare-workers-from-two-italian-hospitals
#16
Graziamaria Corbi, Ignazio Grattagliano, Carlo Sabbà, Giorgio Fiore, Sabrina Spina, Nicola Ferrara, Carlo Pietro Campobasso
With ageing population the number of elderly vulnerable to abuse is expected to grow. Hospital personnel play a crucial role in identifying mistreatment. The aim of this study was to establish the level of awareness and perception of elder abuse by healthcare workers, and to understand if they are able to recognize and properly report elder abuse, as well as to identify the physical signs of abuse and neglect. A 41-question survey was administered to healthcare professionals, working in the Internal Medicine and Geriatric Wards of two different University Hospitals of Southern Italy, representative of the Italian health public system...
January 29, 2019: Internal and Emergency Medicine
https://read.qxmd.com/read/30689135/liver-histopathological-findings-in-advanced-heart-failure-a-reappraisal-of-cardiac-cirrhosis-concept
#17
Emanuele Durante-Mangoni, Antonio Parrella, Pia Clara Pafundi, Martina Vitrone, Enrico Ragone, Ilaria De Rosa, Cristiano Amarelli, Rosa Zampino
Cardiogenic liver disease is a common yet poorly characterized complication of advanced heart failure (HF), and may impact clinical management in the setting of heart transplant evaluation. In this retrospective study, we describe clinical and histopathological features of liver injury in advanced HF, with a focus on the role of liver biopsy. Included were 45 HF patients, assessed for possible heart transplant, who underwent liver biopsy for suspected liver disease. Median duration of HF symptoms was 5 years...
January 28, 2019: Internal and Emergency Medicine
https://read.qxmd.com/read/30684097/update-on-the-treatment-of-beh%C3%A3-et-s-syndrome
#18
Sinem Nihal Esatoglu, Gulen Hatemi
Behçet's syndrome (BS) is a complex disease that shows important heterogeneity in clinical findings and physiopathology. Its treatment can be problematic as BS manifestations in different organs may respond differently to the same drug. The cornerstone of therapy for inducing remission is corticosteroids whereas immunomodulatory and immunosuppressive agents such as colchicine, azathioprine, cyclosporine-A, interferon-alpha, and cyclophosphamide are used as steroid-sparing agents and to prevent further relapses...
January 25, 2019: Internal and Emergency Medicine
https://read.qxmd.com/read/30684096/correction-to-influence-of-frailty-on-anticoagulant-prescription-and-clinical-outcomes-after-1%C3%A2-year-follow%C3%A2-up-in-hospitalised-older-patients-with-atrial-fibrillation
#19
Alejandra Gullón, Francesc Formiga, Jesús Díez-Manglano, José María Mostaza, José María Cepeda, Antonio Pose, Jesús Castiella, Carmen Suárez-Fernández
In the original publication, all the collaborator names were incorrectly tagged and published online. The correct given and family names for the collaborators names should list as follows.
January 25, 2019: Internal and Emergency Medicine
https://read.qxmd.com/read/30659413/long-term-management-of-chronic-heart-failure-patients-in-internal-medicine
#20
Anna Belfiore, Vincenzo Ostilio Palmieri, Carla Di Gennaro, Enrica Settimo, Maria Grazia De Sario, Stefania Lattanzio, Margherita Fanelli, Piero Portincasa
Chronic heart failure (CHF) is one of the main disabilities in elderly patients requiring frequent hospitalizations with high health care costs. We studied the outcome of CHF outpatient management in reducing hospitalization after discharge from a division of Internal Medicine at a large 3rd referral regional Hospital. 147 CHF inpatients (M:F: 63:84; mean age 76 ± 9.6 years) admitted for acute exacerbation of CHF were followed up as outpatients at 1, 6, 12 and 24 months after discharge. At baseline, patients underwent: laboratory tests, ECG, echocardiogram and a dedicated-intensive health care educational program involving also their families...
January 18, 2019: Internal and Emergency Medicine
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