Peder Af Geijerstam, Fredrik Janryd, Fredrik H Nyström
BACKGROUND: Cigarette smoking is a major risk factor for cardiovascular disease. In type 2 diabetes mellitus (T2D), medications such as antihypertensives and statins can reduce the increased cardiovascular risk. The aim of this study was to evaluate the impact of cigarette smoking on major adverse cardiovascular event (MACE) and all-cause mortality in patients with T2D in a relatively well treated Swedish cohort. METHODS: Seven hundred and sixty-one patients with T2D aged 55-66 years were followed in the prospective observational CArdiovascular Risk factors in patients with DIabetes - a Prospective study in Primary care (CARDIPP) study...
September 28, 2023: Journal of Cardiovascular Medicine
Michele Russo, Micol Coccato, Gerlando Preti, Martino Cinquetti, Franco Macor, Nadir Sitta, Francesca Carchesio, Simone Cattarin, Gianluca Piccoli, Roberto Mantovan
No abstract text is available yet for this article.
September 26, 2023: Journal of Cardiovascular Medicine
Wei Zhang, Kui Huang, Jun Qu, Guoying Su, Xinyun Li, Qingzan Kong, Hua Jiang
AIM: The aim of this study was to evaluate the accuracy of the diagnostic criteria for determining the origin of outflow tract ventricular arrhythmia (OTVA) and develop an ECG algorithm to predict its origin. METHOD: We analyzed the ECGs of 100 patients with OTVA who underwent successful ablation. The QRS complex was measured during sinus rhythm and ventricular arrhythmia. After the ECG algorithm was developed, it was validated in an additional 100 patients from two different hospitals...
September 18, 2023: Journal of Cardiovascular Medicine
Marco Zuin, Massimo Imazio, Gianluca Rigatelli, Giampaolo Pasquetto, Claudio Bilato
AIMS: Data regarding the risk of incident pericarditis in coronavirus disease 2019 (COVID-19) recovered patients are lacking. We determined the risk of incident pericarditis after COVID-19 infection by performing a systematic review and meta-analysis of available data. METHODS: Following the PRISMA guidelines, we searched MEDLINE and Scopus to locate all articles published up to 11 February 2023 reporting the risk of incident pericarditis in patients who had recovered from COVID-19 infection compared to noninfected patients (controls) defined as those who did not experience the disease over the same follow-up period...
September 6, 2023: Journal of Cardiovascular Medicine
Michele Senni, Edoardo Sciatti, Elisabetta Bussalino, Emilia D'Elia, Maura Ravera, Ernesto Paoletti
Hyperkalaemia is a life-threatening condition leading to significant morbidity and mortality. It is common in heart failure and in chronic kidney disease (CKD) patients due to the diseases themselves, which often coexist, the high co-presence of diabetes, the fluctuations in renal function, and the use of some drugs [i.e. renin-angiotensin-aldosterone system (RAAS) inhibitors]. Hyperkalaemia limits their administration or uptitration, thus impacting on mortality. New K+ binders, namely patiromer and sodium zirconium cyclosilicate (ZS-9), are an intriguing option to manage hyperkalaemia in heart failure and/or CKD patients, both to reduce its fatal effects and to let clinicians uptitrate RAAS inhibition...
August 31, 2023: Journal of Cardiovascular Medicine
Keitaro Akita, Aaqib Malik, Alexandros Briasoulis, Toshiki Kuno
No abstract text is available yet for this article.
August 30, 2023: Journal of Cardiovascular Medicine
Songqi Yu, Yuxi Sun, Ning Wang, Xin Lv, Jinping Si, Xinxin Zhang, Yanli Zhang, Ying Liu
AIMS: Sodium-glucose cotransporter 2 inhibitors (SGLT2is) have been found to minimize hospitalization for heart failure and cardiovascular death. Cardiac reverse remodeling may be a mechanism responsible for the favorable clinical efficacy of SGLT2is on heart failure. To date, few studies have examined their effects on the left atrium. Therefore, the purpose of this study was to explore whether SGLT2is improve left atrial adverse remodeling in patients with type 2 diabetes and heart failure with reduced ejection fraction (HFrEF)...
August 25, 2023: Journal of Cardiovascular Medicine
Yaqing Zhou, Chen Chen, Long Bai, Limei Jia, Baojin Lu, Guoqiang Gu, Wei Cui
AIMS: Serum alkaline phosphatase (ALP) is known to be associated with cardiovascular events and cerebral arteriosclerosis. However, the link between ALP and early arteriosclerosis remains unclear. This study investigated the relationship between ALP and early arteriosclerosis assessed by brachial-ankle pulse wave velocity (Ba-PWV). METHODS: This retrospective analysis included 5011 participants who underwent health examinations, including ALP and Ba-PWV measurement, at the Second Hospital of Hebei Medical University from 2012 to 2017...
August 15, 2023: Journal of Cardiovascular Medicine
Paolo Alberto Gasparini, Elisa Lodi, Eleonora Rodighiero, Jonathan Rosero Morales, Giuseppe Fantini, Maria Grazia Modena
INTRODUCTION: Data regarding echocardiographic findings during follow-up of asymptomatic or pauci-symptomatic coronavirus disease 2019 (COVID-19) are scarce in pediatric patients. The aim of the present study is to assess post-COVID-19 sequelae through echocardiography in children who have experienced mild SARS-CoV-2. METHODS: This single-center, retrospective, observational study enrolled a cohort of 133 pediatric outpatients, born between 2005 and 2022, with a history of asymptomatic or paucisymptomatic SARS-CoV-2 infection, who underwent transthoracic echocardiographic (TTE) evaluation at an outpatient pediatric clinic in Northern Italy...
August 9, 2023: Journal of Cardiovascular Medicine
Claudio Borghi, Denis Granados
INTRODUCTION: Hypertension affects almost a third of the Italian population and is a major risk factor for cardiovascular disease. Management of hypertension is often hindered by poor adherence to complex treatment regimens. This analysis aimed to estimate the 10-year clinical outcomes associated with single pill combination (SPC) therapies compared with other treatment pathways for the management of hypertension in Italy. METHODS: A microsimulation modeling approach was used to project health outcomes over a 10-year period for people with hypertension...
August 8, 2023: Journal of Cardiovascular Medicine
Bar Rosh, Ibrahim Naoum, Nili Stein, Ronen Jaffe, Walid Saliba
AIMS: Takotsubo syndrome (TTS) is a serious heart disease associated with significant morbidity and mortality. TTS has been related to SARS-CoV-2 infection and COVID-19 vaccine; however, the current data are scarce. We aimed to examine the associations between SARS-CoV-2 infection and its vaccine with TTS. METHODS: We conducted a nested case-control study in a cohort of 3 237 909 adults from the largest healthcare provider in Israel. Patients were followed from 1 March 2020 until 31 December 2021 for the occurrence of TTS...
August 8, 2023: Journal of Cardiovascular Medicine
Xinyi Li, Xiaonan Zhang, Zhigang Zeng, Wenzhi Mai, Zishan Peng, Binjia Li, Wanzi Hong, Yaoxin Liu, Fen Shu, Jiehua Tang, Lishu Xu, Ning Tan, Jinjin Ma, Lei Jiang
AIMS: Hypoalbuminemia was extensively used to diagnose malnutrition in older adults. Malnutrition was associated with mortality in elderly patients with cardiovascular diseases. The relationship between hypoalbuminemia and clinical outcomes in elderly patients with nonischemic dilated cardiomyopathy (NIDCM) remains unknown. METHODS: A total of 1058 consecutive patients with NIDCM (age ≥60 years) were retrospectively enrolled from January 2010 to December 2019...
August 4, 2023: Journal of Cardiovascular Medicine
Andrea Mazza, Mauro Iafrancesco, Piergiorgio Bruno, Giovanni Alfonso Chiariello, Carlo Trani, Francesco Burzotta, Federico Cammertoni, Annalisa Pasquini, Giovanni Diana, Raphael Rosenhek, Giovanna Liuzzo, Alessia Rabini, Andrea Flex, Abdallah Raweh, Filippo Crea, Massimo Massetti
AIMS: Despite general agreement on the benefits of the Heart Team approach for patients with cardiac diseases, few data are available on its real impact on the decision-making process. The aim of the study is to define the evolution over time of the level of agreement with the systematic discussion of patients in the Heart Team and to evaluate the adherence to the Heart Team recommendations and the impact of the Heart Team on the clinical outcome of the patients. METHODS: In 2015--2016, an experienced cardiac surgeon and a cardiologist independently reviewed clinical data of a series of 100 patients (Group 1, G1) and subsequently for each patient recommended treatment (surgical, percutaneous, hybrid or medical therapy) or further diagnostic investigations...
August 3, 2023: Journal of Cardiovascular Medicine
Dimitris Tsiachris, Francesco Giannini, Christos-Konstantinos Antoniou, Kyriakos Dimitriadis, Christodoulos Stefanadis, Konstantinos Tsioufis
No abstract text is available yet for this article.
August 3, 2023: Journal of Cardiovascular Medicine
Lorenzo Di Bacco, Michele D'Alonzo, Massimiliano Di Mauro, Rocco Davide Petruccelli, Massimo Baudo, Camila Mayorga Palacios, Stefano Benussi, Claudio Muneretto, Fabrizio Rosati
AIMS: Timing and surgical strategies in acute infective endocarditis are still questionable. We sought to investigate clinical outcomes of patients undergoing mitral valve repair (MVR) compared with mitral valve replacement [mitral valve prosthesis (MVP)] for acute infective endocarditis. METHODS: From 2004 to 2019, 109 consecutive patients with acute mitral valve infective endocarditis were retrospectively investigated. Patients were divided into two groups according to surgical strategy: MVR 53/109 (48...
August 3, 2023: Journal of Cardiovascular Medicine
Spyros Kolovos, Leana Bellanca, Harinala Groyer, Giuseppe Rosano, Jennifer Gaultney, Stephan Linden
AIMS: Heart failure (HF) is a complex syndrome commonly categorized into two main phenotypes [left ventricular ejection fraction (LVEF) below or above 40%], and although empagliflozin is the first approved medication with proven clinical effectiveness for both phenotypes, its cost-effectiveness of treating the entire HF population remains unknown. METHODS: The analysis was performed utilizing two preexisting, LVEF phenotype-specific cost-effectiveness models to estimate the cost-effectiveness of empagliflozin in adults for the treatment of symptomatic chronic HF, irrespective of ejection fraction (EF)...
July 26, 2023: Journal of Cardiovascular Medicine
Ayodeji I Ilelaboye, Ufuk Vardar, Naveen Baskaran, Abdultawab Shaka, Sean DeAngelo, Hafeez Shaka
The effect of the pandemic on patient care and health care delivery is unprecedented. The aim of this study was to assess the impact of the COVID 19 pandemic on the epidemiological trends and disparities in the outcomes of patients hospitalized for heart failure. This was a retrospective study involving hospitalizations for HF. We sourced data from the NIS databases from 2016 through 2020. The study involved hospitalizations for HF as the principal diagnosis. These conditions were matched with CCSR categories...
July 7, 2023: Journal of Cardiovascular Medicine
Marco Zuin, Michele Malagù, Francesco Vitali, Martina De Raffele, Cristina Balla, Matteo Bertini
AIMS: We sought to assess the atrial fibrillation/flutter (AF/AFL) mortality rates and relative trends among the Italian population between 2003 and 2017. METHODS: Data regarding the cause-specific mortality and population size by sex in 5-year age groups were extracted from the World Health Organization (WHO) global mortality database. Decedents reporting the codes I48 were extracted accordingly to the International Classification of Disease-10 (ICD-10) coding system...
July 6, 2023: Journal of Cardiovascular Medicine
Afiachukwu Onuegbu, Francesca Calicchio, April Kinninger, Rine Nakanishi, John J Carr, Khurram Nasir, Rebecca Gottesman, Matthew Budoff
BACKGROUND: Mitral annular calcification (MAC) is associated with an increased risk for cardiovascular morbidity and mortality. This study provides recent data on the association between cardiac computed tomography (CT) derived MAC and 15 years of stroke risk in a racially diverse cohort. METHODS: All multiethnic studies of atherosclerosis participants (n = 6814) who completed a cardiac CT at baseline were included in this analysis. MAC score was calculated from cardiac CT using the Agatston and volume score methods...
July 6, 2023: Journal of Cardiovascular Medicine
Edoardo Sciatti, Anna Merlo, Aurelia Grosu, Giulio Balestrieri, Umbertina Veritti, Vincenzo Duino, Michele Senni
No abstract text is available yet for this article.
November 1, 2023: Journal of Cardiovascular Medicine
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