Ben Ainsworth, Jeremy Horwood, Scott R Walter, Sascha Miller, Melanie Chalder, Frank De Vocht, James Denison-Day, Martha M C Elwenspoek, Helen J Curtis, Chris Bates, Amir Mehrkar, Seb Bacon, Ben Goldacre, Pippa Craggs, Richard Amlôt, Nick Francis, Paul Little, John Macleod, Michael Moore, Kate Morton, Cathy Rice, Jonathan Sterne, Beth Stuart, Lauren Towler, Merlin L Willcox, Lucy Yardley
BACKGROUND: Germ Defence ( www.germdefence.org ) is an evidence-based interactive website that promotes behaviour change for infection control within households. To maximise the potential of Germ Defence to effectively reduce the spread of COVID-19, the intervention needed to be implemented at scale rapidly. METHODS: With NHS England approval, we conducted an efficient two-arm (1:1 ratio) cluster randomised controlled trial (RCT) to examine the effectiveness of randomising implementation of Germ Defence via general practitioner (GP) practices across England, UK, compared with usual care to disseminate Germ Defence to patients...
December 4, 2023: Implementation Science: IS