journal
Journals Therapeutics and Clinical Risk...

Therapeutics and Clinical Risk Management

https://read.qxmd.com/read/38532744/the-use-of-preoperative-video-distraction-on-emergence-delirium-in-preschool-children-undergoing-strabismus-surgery-under-anesthesia-with-sevoflurane-a-randomized-controlled-trial
#1
Yue Wang, Liyan Chu, He Li, Yingjie Du, Shanshan Wang, Ying Liu, Guyan Wang
PURPOSE: The aim of this study was to determine whether preoperative video distraction reduces the incidence of emergence delirium in preschool children under general anesthesia with sevoflurane. PATIENTS AND METHODS: In this prospective randomized controlled study, children aged 3-6 years were randomized to receive either video distraction (Group V) or common clinical practice (Group C) from arrival at the holding area to induction of anesthesia. The primary outcome was the incidence of emergence delirium...
2024: Therapeutics and Clinical Risk Management
https://read.qxmd.com/read/38524687/determinants-of-metabolic-syndrome-among-patients-receiving-anti-retro-viral-treatment-in-a-tertiary-hospital-central-ethiopia-unmatched-case-control-study
#2
JOURNAL ARTICLE
Godana Jarso, Haji Aman, Abebe Megerso
PURPOSE: Scaling up antiretroviral treatment (ART) reduces morbidity and mortality among people living with HIV/AIDS (PLHA). This success is challenged by the constellation of interrelated metabolic disorders such as metabolic syndrome (MetS). Given the changing ART regimens and schedules, increasing patient age and methodological limitations, existing evidence regarding the determinants of MetS remains inconclusive. Therefore, in the current study, we aimed to identify the determinants of MetS in patients receiving ART at a tertiary hospital in central Ethiopia...
2024: Therapeutics and Clinical Risk Management
https://read.qxmd.com/read/38524686/effect-of-aggressive-warming-versus-routine-thermal-management-on-the-incidence-of-perioperative-hypothermia-in-patients-undergoing-thyroid-surgery-a-prospective-randomized-double-blind-controlled-trial
#3
JOURNAL ARTICLE
Yue Zhang, Yafan Bai, Yi Zhang, Yingjie Du, Min Liu, Jiayu Zhu, Guyan Wang
PURPOSE: Despite the implementation of various insulation measures, the incidence of hypothermia during thyroid surgery remains high. This randomized controlled study aimed to evaluate the effects of aggressive thermal management combined with resistive heating mattresses to prevent perioperative hypothermia in patients undergoing thyroid surgery. PATIENTS AND METHODS: 142 consecutive patients scheduled for elective thyroid surgery were enrolled in the study. They were randomly and equally allocated to the aggressive warming or routine care groups (n = 71)...
2024: Therapeutics and Clinical Risk Management
https://read.qxmd.com/read/38496352/longitudinal-study-on-pre-and-post-operation-ct-imaging-for-predicting-pedicle-screw-loosening-in-patients-with-lumbar-degenerative-disease
#4
JOURNAL ARTICLE
Qian Zhang, Fanfan Zhao, Yu Zhang, Xiangyang Gong
PURPOSE: We conducted a longitudinal study to examine the predictive role of risk factors in the occurrence of pedicle screw loosening, assessed through pre- and post-operative computed tomography (CT) scans. METHODS: A total of 103 patients with degenerative lumbar disease who had undergone L4/5 pedicle screw fixation (involving 412 screws) were included in this study. They were subsequently categorized into two groups-the "loosening group" and the "non-loosening group"...
2024: Therapeutics and Clinical Risk Management
https://read.qxmd.com/read/38476881/risk-factors-of-chylothorax-after-congenital-heart-surgery-in-infants-a-single-centre-retrospective-study
#5
JOURNAL ARTICLE
Rui-Gui Zhang, Yu-Mei Liu, Zhi-Ye Yao, Jing-Xuan Fang, Yuan Li, Man-Li Zheng, Xin Sun, Shu-Sheng Wen, Xi-Meng Wang, Jian Zhuang, Dan-Dong Luo, Shao-Ru He
BACKGROUND: Studies of chylothorax after congenital heart disease in infants are rare. Chylothorax has a higher incidence in infancy, but its risk factors are not well understood. OBJECTIVE: The purpose of this study is to investigate the risk factors of chylothorax after congenital heart surgery in infants. METHODS: This retrospective study included 176 infants who underwent congenital heart disease surgery at the Guangdong Cardiovascular Institute, China, between 2016 and 2020...
2024: Therapeutics and Clinical Risk Management
https://read.qxmd.com/read/38463615/safety-of-early-discharge-among-low-risk-patients-after-primary-percutaneous-coronary-intervention-an-updated-systematic-review-and-meta-analysis
#6
REVIEW
Firman Sugiharto, Yanny Trisyani, Aan Nuraeni, Praneed Songwathana
BACKGROUND: Guidelines for early discharge (ED) strategies after primary percutaneous coronary intervention (PPCI) in low-risk patients still need to be informed. Previous meta-analysis evidence is considered to have limitations, from the level of heterogeneity, which is still relatively high, and the sample size still needed to be more significant. PURPOSE: This study aims to identify the safety of early discharge after PPCI in low-risk patients. METHODS: The literature search used five primary databases: CINAHL, PubMed, ScienceDirect, Scopus, Taylor and Francis, and one search engine: Google Scholar...
2024: Therapeutics and Clinical Risk Management
https://read.qxmd.com/read/38434107/assessment-of-pharmacokinetic-effects-of-herbal-medicines-on-escitalopram
#7
JOURNAL ARTICLE
Yun Seob Jung, Byung Hak Jin, Ju Eun Choi, Min Soo Park, Young-Woo Kim, Hyung Won Kang, Sunyoung Cho, Choon Ok Kim
PURPOSE: Herbal medicines are occasionally used in combination with conventional antidepressants to mitigate various depression-associated symptoms. However, there is limited information on herb-antidepressant interactions. In this study, we investigated the pharmacokinetic (PK) effects of four herbal medicines (Gami-soyosan, Banhasasim-tang, Ojeok-san, and Bojungikgi-tang) on escitalopram, a commonly used antidepressant. PATIENTS AND METHODS: In this open-label, fixed-sequence, three-period, crossover study, 18 participants were enrolled and divided into two groups...
2024: Therapeutics and Clinical Risk Management
https://read.qxmd.com/read/38410117/classification-and-regression-tree-predictive-model-for-acute-kidney-injury-in-traumatic-brain-injury-patients
#8
JOURNAL ARTICLE
Ruoran Wang, Jing Zhang, Min He, Jianguo Xu
BACKGROUND: Acute kidney injury (AKI) is prevalent in hospitalized patients with traumatic brain injury (TBI), and increases the risk of poor outcomes. We designed this study to develop a visual and convenient decision-tree-based model for predicting AKI in TBI patients. METHODS: A total of 376 patients admitted to the emergency department of the West China Hospital for TBI between January 2015 and June 2019 were included. Demographic information, vital signs on admission, laboratory test results, radiological signs, surgical options, and medications were recorded as variables...
2024: Therapeutics and Clinical Risk Management
https://read.qxmd.com/read/38379850/descemetic-deep-anterior-lamellar-keratoplasty-versus-penetrating-keratoplasty-in-advanced-keratoconus-comparison-of-visual-and-refractive-outcomes
#9
JOURNAL ARTICLE
Leopoldo Spadea, Lucia Di Genova, Edoardo Trovato Battagliola, Stefano Scordari
PURPOSE: To assess and contrast the visual and refractive results of Descemetic deep anterior lamellar keratoplasty (DALK) and penetrating keratoplasty (PK) in the treatment of advanced keratoconus. DESIGN: Retrospective, comparative, interventional study. METHODS: This study enrolled eyes affected by keratoconus with preoperative mean keratometry ≥60 diopters (D) that were treated with either Descemetic DALK (30 eyes) or PK (29 eyes) by using always the same corneal diameters (8...
2024: Therapeutics and Clinical Risk Management
https://read.qxmd.com/read/38375076/effectivity-of-virtual-reality-to-improve-balance-motor-function-activities-of-daily-living-and-upper-limb-function-in-children-with-cerebral-palsy-a-systematic-review-and-meta-analysis
#10
REVIEW
Maria Komariah, Shakira Amirah, Muhammad Fahd Abdurrahman, Mohammad Farrel Shaquille Handimulya, Hesti Platini, Sidik Maulana, Annisa Dewi Nugrahani, Aep Maulid Mulyana, Shurouq Ghalib Qadous, Henny Suzana Mediani, Arpit Mago
BACKGROUND: Cerebral palsy (CP) is the most common motor disorder in childhood. CP limits movement, which can interfere with children's daily activities. As a technology that provides intensive mass practice to children, virtual reality (VR) can create an interactive and motivating environment. With the intensity set by the therapist and feedback that can be used to produce individualized therapy, VR has great potential to improve CP patients' quality of life, especially in a safe, enjoyable, and playful environment...
2024: Therapeutics and Clinical Risk Management
https://read.qxmd.com/read/38375075/challenges-in-the-early-diagnosis-and-treatment-of-chronic-inflammatory-demyelinating-polyradiculoneuropathy-in-adults-current-perspectives
#11
REVIEW
Iris N van Doorn, Filip Eftimov, Luuk Wieske, Ivo N van Schaik, Camiel Verhamme
Diagnosing Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) poses numerous challenges. The heterogeneous presentations of CIDP variants, its mimics, and the complexity of interpreting electrodiagnostic criteria are just a few of the many reasons for misdiagnoses. Early recognition and treatment are important to reduce the risk of irreversible axonal damage, which may lead to permanent disability. The diagnosis of CIDP is based on a combination of clinical symptoms, nerve conduction study findings that indicate demyelination, and other supportive criteria...
2024: Therapeutics and Clinical Risk Management
https://read.qxmd.com/read/38351954/acthar-gel-in-african-americans-versus-non-african-americans-with-symptomatic-sarcoidosis-physician-assessment-of-patient-medical-records
#12
JOURNAL ARTICLE
Jas Bindra, Ishveen Chopra, Kyle Hayes, John Niewoehner, Mary Prince Panaccio, George J Wan
INTRODUCTION: Sarcoidosis is common among African Americans in the United States. Acthar® Gel is a viable option for the treatment of advanced symptomatic sarcoidosis. This study examined patient characteristics, Acthar Gel utilization, co-medication use, and treatment response based on physicians' assessments among African Americans versus non-African Americans with advanced symptomatic sarcoidosis. METHODS: Data from the medical charts of patients were used...
2024: Therapeutics and Clinical Risk Management
https://read.qxmd.com/read/38351953/minimally-invasive-treatment-of-chyle-leak-after-thyroidectomy-and-cervical-lymph-node-dissection-in-patients-with-thyroid-carcinoma-results-of-a-study-involving-36-patients
#13
JOURNAL ARTICLE
Nguyen Ngoc Cuong, Le Hoan, Thieu Thi Tra My, Doan Tien Luu, Le Tuan Linh, Pham Hong Canh, Trieu Quoc Tinh, Tran Nguyen Khanh Chi, Nguyen Quang Trung, Tran Quoc Hoa
OBJECTIVE: Chyle leak (CL) after head and neck surgery is a rare but well-known complication. In patients with high-output leakage, the treatment can be complicated. This study aims to report on a recent innovation in lymphatic intervention for treating such patients. MATERIALS AND METHODS: A retrospective review of 36 patients with chyle leak after neck surgery for thyroid cancer was conducted to assess the efficacy of percutaneous lymphatic embolization and thoracic duct (TD) disruption...
2024: Therapeutics and Clinical Risk Management
https://read.qxmd.com/read/38347921/treatment-patterns-and-flt3-mutation-testing-among-patients-with-acute-myeloid-leukemia-in-china-a-retrospective-observational-study
#14
JOURNAL ARTICLE
Benfa Gong, Li-Jen Cheng, Christopher H Young, Prabhuram Krishnan, Ying Wang, Hui Wei, Chunlin Zhou, Shuning Wei, Yan Li, Qiuyun Fang, Jia Zhong, Eric Q Wu, Yingchang Mi, Jianxiang Wang
INTRODUCTION: For acute myeloid leukemia (AML), prognosis is particularly poor in patients harboring FMS-like tyrosine kinase 3 ( FLT3 ) gene mutations, though routine screening for these mutations at diagnosis has been shown to be insufficient. The understanding of the impact of FLT3 mutations on treatment decisions is limited. METHODS: In this retrospective, observational study, we investigated the key epidemiological characteristics, treatment patterns and responses among adult patients with newly diagnosed (ND) AML in China, who initiated treatment from January 1, 2015, to December 31, 2019, or progressed to relapsed/refractory (R/R) AML by December 31, 2020...
2024: Therapeutics and Clinical Risk Management
https://read.qxmd.com/read/38344195/factors-influencing-the-fasting-time-in-adult-patients-after-the-endoscopic-management-of-sharp-esophageal-foreign-bodies
#15
JOURNAL ARTICLE
Da-Quan Wu, Shu-Yang Chen, Ke-Guang Chen, Tan Wang, Guang-Yao Li, Xin-Sheng Huang
BACKGROUND: Sharp esophageal foreign body (SEFB) impaction can cause varying degrees of damage to the esophagus. There are few studies analyzing the postoperative fasting time in SEFB patients. METHODS: We retrospectively collected 835 SEFB patients. According to the fasting time after the endoscopic removal (ER) of SEFBs, the patients were divided into two groups: short fasting time (SFT, fasted ≤24 h) and long fasting time (LFT, fasted >24 h). RESULTS: There were 216 and 619 patients in the SFT and LFT group, respectively...
2024: Therapeutics and Clinical Risk Management
https://read.qxmd.com/read/38344194/lasso-based-identification-of-risk-factors-and-development-of-a-prediction-model-for-sepsis-patients
#16
JOURNAL ARTICLE
Chengying Hong, Yihan Xiong, Jinquan Xia, Wei Huang, Andi Xia, Shunyao Xu, Yuting Chen, Zhikun Xu, Huaisheng Chen, Zhongwei Zhang
OBJECTIVE: The objective of this study was to utilize LASSO regression (Least Absolute Shrinkage and Selection Operator Regression) to identify key variables in septic patients and develop a predictive model for intensive care unit (ICU) mortality. METHODS: We conducted a cohort consisting of septic patients admitted to the ICU between December 2016 and July 2019. The disease severity and laboratory index were analyzed using LASSO regression. The selected variables were then used to develop a model for predicting ICU mortality...
2024: Therapeutics and Clinical Risk Management
https://read.qxmd.com/read/38288358/the-potential-of-autologous-platelet-rich-plasma-gel-for-diabetic-foot-ulcer-care-among-older-adults-a-systematic-review-and-meta-analysis
#17
REVIEW
Hesti Platini, Keyzha Amartya Adammayanti, Sidik Maulana, Putu Moradha Kharisma Putri, Welly Grivin Layuk, Juan Alessandro Jeremis Maruli Nura Lele, Hartiah Haroen, Sri Hartati Pratiwi, Faizal Musthofa, Arpit Mago
INTRODUCTION: Poorly controlled diabetes mellitus can lead to the development of diabetic foot ulcers (DFU), which is a frequent complication in patients. However, several diabetes management guidelines for older adults do not mention the occurrence of DFUs. Nowadays, Autologous Platelet-Rich Gel (APG) is being used for treating diabetic ulcers. APG is an innovative platelet-derived product with many advantages, such as being low-cost, easy to produce, and readily available materials...
2024: Therapeutics and Clinical Risk Management
https://read.qxmd.com/read/38250050/erratum-hard-candy-consumption-does-not-have-an-effect-on-volume-and-ph-of-gastric-content-in-patients-undergoing-elective-gastrointestinal-endoscopic-procedures-a-randomized-controlled-trial-corrigendum
#18
(no author information available yet)
[This corrects the article DOI: 10.2147/TCRM.S377421.].
2024: Therapeutics and Clinical Risk Management
https://read.qxmd.com/read/38230373/profile-of-sofosbuvir-and-velpatasvir-combination-in-the-treatment-of-chronic-hepatitis-c-in-children-and-adolescents-current-evidence
#19
REVIEW
Dania Brigham, Michael R Narkewicz
Chronic hepatitis C (HCV) affects up to 3.25 million children and adolescents. Early treatment of HCV in children and adolescents reduces progression to advanced liver disease and cancer. Treatment for HCV has evolved to highly effective direct acting antiviral therapy in adults and now in children ≥3 years of age. This review focuses on the role of sofosbuvir and velpatasvir (SOF/VEL), a newer treatment of children and adolescents with chronic HCV. SOF/VEL is a pangenotypic DAA with primary clearance via the liver and biliary excretion...
2024: Therapeutics and Clinical Risk Management
https://read.qxmd.com/read/38230372/the-efficacy-and-safety-of-diazepam-for-intraoperative-blood-pressure-stabilization-in-hypertensive-patients-undergoing-vitrectomy-under-nerve-block-anesthesia-a-prospective-single-center-double-blind-randomized-controlled-trial
#20
Tianwei Qian, Qiaoyun Gong, Yiyang Shu, Hangqi Shen, Xia Wu, Weijun Wang, Zhihua Zhang, Hui Cao, Xun Xu
PURPOSE: To evaluate the effectiveness and safety of diazepam in maintaining stable intraoperative blood pressure (BP) in hypertensive patients undergoing vitrectomy under nerve block anesthesia. METHODS: A total of 180 hypertensive patients undergoing vitrectomy with nerve block anesthesia were randomized into two groups. The intervention group was given oral diazepam 60 min before operation, while the control group was given oral placebo 60 min before operation...
2024: Therapeutics and Clinical Risk Management
journal
journal
41122
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.