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Clinical Otolaryngology

Stefan Grasl, Lorenz Kadletz, Stefan Janik, Agnes Riedl, Birgit Erlacher, Michael Formanek, Matthaeus C Grasl, Boban M Erovic
Salivary gland tumors represent a group of heterogeneous lesions with distinct biological behavior and complex clinicopathological characteristics. In 70% of the cases the parotid gland is affected and in about 80% the tumor is benign.1 In general, an accurate diagnosis of parotid tumors consists of a triple assessment, comprising clinical examination, imaging and histological or cytological analysis. This article is protected by copyright. All rights reserved.
February 19, 2019: Clinical Otolaryngology
M Tan, K L Whitcroft, N Mehta, A Schilder, T S Leung, P Andrews
OBJECTIVE: To plot the nasal cycle using unilateral peak nasal inspiratory flow (UPNIF) and unilateral minimal cross-sectional area (UMCA) readings demonstrating a linear relationship in normal nasal function. Additionally, to determine how this changes in abnormal nasal function. DESIGN: A cross-sectional study measuring UPNIF and UMCA in controls demonstrating normal nasal function and in patients with nasal obstruction. SETTING: Royal National Throat Nose and Ear Hospital, London...
February 15, 2019: Clinical Otolaryngology
H B Do, T Ohbuchi, M Yokoyama, T Kitamura, T Wakasugi, J-I Ohkubo, H Suzuki
OBJECTIVE: We investigated the difference in ciliary beat responsiveness to acetylcholine in ex vivo and the difference in the expressions of associated molecules (M1/M3 muscarinic receptors, pannexin-1 and P2X7 purinergic receptor) between the nasal polyp and turbinate mucosa. STUDY DESIGN: Laboratorial study. PARTICIPANTS: Nasal polyp and inferior turbinate were collected from patients with hypertrophic rhinitis and/or nasal polyp during endoscopic sinonasal surgery...
February 14, 2019: Clinical Otolaryngology
İrfan Kara, Sedat Çağlı, Alperen Vural, İmdat Yüce, Mete Gündoğ, Kemal Deniz, Kerem Kökoğlu
OBJECTIVES: To investigate the relationship between the cell percentage of T regulator (Treg) cells of patients' specimens and disease severity, survivability, recurrence and metastasis in patients who were diagnosed with nasopharyngeal carcinoma (NPC). DESIGN: Sixty patients who were diagnosed as NPC and treated by the same protocol were enrolled to the study. Patient files were reviewed retrospectively and their clinical and pathological results were recorded...
February 12, 2019: Clinical Otolaryngology
Shih-Han Hung, Sudha Xirasagar, Yen-Fu Cheng, Herng-Ching Lin
OBJECTIVE: The purpose of this study was to evaluate the association between osteoporosis and salivary gland stone using a population-based claims database. DESIGN: A case-control design. SETTING: Taiwan. PARTICIPANTS: We retrieved the sample for this case-control study from the Taiwan "Longitudinal Health Insurance Database 2005". All 557 patients aged 40 years or older with a diagnosis of sialolithiasis were cases and 1671 matched controls (without sialolithiasis) were selected...
February 11, 2019: Clinical Otolaryngology
Sofia Sousa, Francisco Patrão, Gabriel Pereira, Eurico Monteiro
Juvenile nasopharyngeal angiofibroma (JNA) is a benign, rare and highly vascular tumour, occurring in adolescent males. Clinical records of 27 patients who underwent surgical resection, performed between 1989 and 2017, were reviewed. Three patients were submitted to paralatero-nasal rhinotomy, 23 patients (85%), to the sublabial transnasomaxillary approach (Rouge Denker approach), complemented in 19 (70.0%) with transpalatine approach (Wilson technique). Endoscopic resection was performed only at one patient stage IB...
February 9, 2019: Clinical Otolaryngology
MeiRong Yang, Haiyue Jiang, Ye Zhang, Bo Pan
1、New method using expander makes auricular reconstruction easier. 2、Most patients were satisfied with reconstructed ears. 3、Reconstructed ears showed good three-dimensional shape with clear anatomical details and symmetric cranioauricular angle. 4、Retroauricular and chest scars were much smaller. 5、Compared with traditional method,new method takes shorter operation time in the second stage. This article is protected by copyright. All rights reserved.
February 8, 2019: Clinical Otolaryngology
Sander W J Ubbink, Rutger Hofman, Pim van Dijk, J Marc C van Dijk
In pulsatile tinnitus, the differential diagnosis includes neurovascular pathology, which can be occult on non-invasive imaging techniques. Therefore, if a clear diagnosis is lacking, digital subtraction angiography (DSA) is indicated to rule out a potentially hazardous vascular lesion, particularly a dural arteriovenous fistula (dAVF). However, a DSA carries a procedural risk of 1-2%. In a tertiary care setting, the incidence of a dAVF in pulsatile tinnitus patients lacking a diagnosis after non-invasive imaging is about 25-35%...
February 8, 2019: Clinical Otolaryngology
Esma Evrim Dogan, Mustafa Uslu, Melda Comert Ozkan, Hatice Demet Kiper Unal, Guray Saydam, Mehmet Fatih Ogut, Mahmut Tobu
•Patients with PV may present with sensorineural hearing loss, acute hearing loss, and vertigo. The aim of this study was to determine the effect of Polycytemia vera (PV) on hearing functions. •Patients with known PV (n=21) were compared to healthy controls with no history of otologic or neurologic disorders (n = 20). Cochlear impairment was found to be significantly increased in PV group (p=0,004). There was no statistically significant difference between the groups in means of Hgb and Htc (p=0,629)...
February 8, 2019: Clinical Otolaryngology
Ezzeddin Elsheikh, Mohammad Waheed El-Anwar
Palatal fistula and velopharyngeal insufficiency are the commonest complications of cleft palate surgery. For patients with cleft soft palate, beside hard palate VY push back flaps, two soft palate bi-pedicle flaps were made on each sides of the posterior palate to dissect and push soft palate back and medial closing the VP valve. In operated 26 children, sutures were tensionless and palatal integrity could be achieved in all patients without reported postoperative bleeding, fistula, infection, suture release, or granulation...
February 7, 2019: Clinical Otolaryngology
Hayoung Byun, Jae Ho Chung, Seung Hwan Lee, Chul Won Park, Dong Woo Park, Tae Yoon Kim
OBJECTIVE: The aim of this study was to investigate the clinical significance of 4-hour delayed-enhanced 3.0 Tesla (3T) 3D-fluid attenuated inversion recovery (FLAIR) MR imaging in sudden sensorineural hearing loss (SSNHL). STUDY DESIGN: Case series with comparisons. SETTING: Tertiary referral centre. PARTICIPANTS: Eighty-seven idiopathic SSNHL patients were enrolled between January 2015 and December 2016 and received high dose steroid therapy and intratympanic steroid injections as salvage treatment...
February 7, 2019: Clinical Otolaryngology
Waqas Bin Majid Din, Gerard Kelly, Cindy Liu
Battery foreign bodies in the external auditory canal or nasal cavity are an ENT emergency, and require immediate removal. The purposely-designed fine magnet probe as described in this paper, allows safe and prompt removal of a ferrous foreign body from the ear canal with minimal trauma. Widespread use of a fine magnet probe is proposed in ENT clinics and in the acute situation, for removal of ferrous foreign bodies. This method is quick, safe, well tolerated and cost efficient. This article is protected by copyright...
February 7, 2019: Clinical Otolaryngology
Feike de Graaff, Elke Huysmans, Birgit Philips, Paul Merkus, S Theo Goverts, Sophia E Kramer, Cas Smits
The number of CI users has grown rapidly, resulting in an increased workload for CI centres and a need for new and innovative ways to provide healthcare to users of a CI. A telehealth application was developed with a functionality to self-administer speech recognition tests at home, which was evaluated in 10 newly-implanted patients. Speech recognition in quiet and in noise improved steadily during the first few weeks of rehabilitation, after which it stabilized. The home tests provided a good alternative to testing in the clinic for newly-implanted patients who were able and willing to perform part of their CI care from home, and felt confident in using the technology required...
February 7, 2019: Clinical Otolaryngology
Joshua D Whittaker, Wai Sum Cho, Sameer Mallick
Laryngectomised patients are at inherent risk of inhalation of foreign bodies, which can be an emergency airway situation. A retrofitted flexible nasendoscope can be a safe, effective and a more familiar instrument for otolaryngologists, especially when the procedure needs to be undertaken out of hours. Conducting the procedure with nebulised local anaesthetic and sedation is favourable in patients with high burden of comorbid disease and makes the procedure well tolerated. This article is protected by copyright...
February 7, 2019: Clinical Otolaryngology
Kate Hulse, Adam Williamson, Fraser Gibb, Brendan Conn, Iain J Nixon
Objectives To assess the impact of the eighth edition AJCC/TMN staging system on patients with new diagnoses of differentiated thyroid cancers presenting to our regional multi-disciplinary team meetings. Design We analysed Endocrine Cancer MDT meeting records from 2009-2015 to identify all patients in the region presenting with a new diagnosis of differentiated thyroid cancer. We re-staged patients according to the eighth edition AJCC/TNM staging classification and analysed the survival outcomes of patients in each stage under the seventh and eighth systems...
February 5, 2019: Clinical Otolaryngology
Nadège Costa, Michael Mounié, Geraldine Bernard, Laurent Bieler, Laurent Molinier, Elie Serrano, Guillaume de Bonnecaze
OBJECTIVES: Trans-nasal endoscopic sphenopalatine artery ligation (TESPAL) and endovascular arterial embolisation both provide excellent success rates for intractable epistaxis. Recent economic models suggest that TESPAL could be a cost-saving strategy. Our main aim was to perform cost-effectiveness analyses on TESPAL compared to embolisation to treat patients with epistaxis. DESIGN: We performed a retrospective, monocentric, comparative analyses on patients referred to our center and treated with embolisation or TESPAL...
February 5, 2019: Clinical Otolaryngology
Kiran Varadharajan, Natasha Choudhury, Hesham A Saleh
The internal nasal valve (INV) is bound by the nasal septum, inferior turbinate and the upper lateral cartilage (ULC). It is the most important determinant of nasal airflow, and critical for nasal breathing. The normal internal nasal valve angle is 10-15o .1  Even a small change in the INV angle can have a significant impact on nasal airflow. This article is protected by copyright. All rights reserved.
February 1, 2019: Clinical Otolaryngology
Y C Lee, A R Jung, O E Kwon, J W Kang, J H Huh, Y G Eun
Thirty-two patients with refractory LPR confirmed by 24-h MII-pH were given a 3-month course of baclofen 10 mg three times a day combined with PPI 15 mg twice a day. Changes in RSI and reflux-related quality of life from baseline to after treatment were evaluated. MII-pH monitoring of refractory LPR patients showed that the number of non-acid reflux was much higher than acid reflux in laryngopharyngeal reflux and full-column reflux. After 3 months of PPI + baclofen medication, most RSI items and quality of life score showed a significant improvement compared to the baseline score, and the percentage of responders at 3 months was 53...
January 31, 2019: Clinical Otolaryngology
Lifang Cui, Congling Qu, Honggang Liu
OBJECTIVE: To investigate the role of human papillomavirus (HPV) in laryngeal squamous cell carcinoma (LSCC) and analyze the relationship between HPV and the expression of cell cycle-related proteins. DESIGN: The study consisted of LSCC between 2005 and 2011 in Tongren Hospital. Clinical data such as age, sex, smoking/ alcohol consumption and TNM stage were collected. HPV DNA and cell cycle-related proteins were assessed in terms of clinical features. SETTING: Single center study...
January 25, 2019: Clinical Otolaryngology
A Kaura, J S Virk, J Joseph, C Rennie, P S Randhawa, P J Andrews
Nasal Inspiratory Peak Flow (NIPF) poorly correlates with subjective patient reported outcomes (PROMs) following functional septorhinoplasty. The aim of this study is to determine whether unilateral NIPF correlates with PROMs. The study demonstrates significant improvement in objective and subjective measurements post septorhinoplasty surgery in seventy patients. There was weak correlation between improvements in bilateral NIPF when compared with changes in the NOSE score. Whilst unilateral NIPF does not correlate with subjective outcome scores, it is still a useful measure in assessing nasal patency and in patient education...
January 25, 2019: Clinical Otolaryngology
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