Shishu Singh, Josée Guindon, Prapti Mody, Jonathan Kopel, Sai Chilakapati, Owoicho Adogwa, Volker Neugebauer, Michael D D Burton, Gabriela Arandia
Chronic pain is one of the most common, costly, and potentially debilitating health issues facing older adults, with attributable costs exceeding $600 billion annually. The prevalence of pain in humans increases with advancing age. Yet, the contributions of sex differences, age-related chronic inflammation, and changes in neuroplasticity to the overall experience of pain are less clear, given that opposing processes in aging interact. This review article examines and summarizes pre-clinical research and clinical data on chronic pain among older adults to identify knowledge gaps and provide the base for future research and clinical practice...
September 8, 2023: Molecular Pain