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Cardiovascular Revascularization Medicine: Including Molecular Interventions

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https://read.qxmd.com/read/30760412/outcomes-of-coronary-artery-revascularization-procedures-in-patients-with-antiphospholipid-syndrome
#1
Navid Ahmed, Himali Gandhi, Eliany Mejia Lopez, Neeraja Yedlapati, Daniel Spevack
BACKGROUND: Published data on the outcome of coronary artery revascularization in patients with antiphospholipid syndrome (APS) are limited. Because APS is associated with a high rate of arterial thrombosis, there is concern that coronary revascularization in this group may be complicated by increased need for repeat revascularization. We aimed to determine the incidence and timing of repeat revascularization performed in patients with APS undergoing percutaneous coronary interventions (PCI) or coronary artery bypass grafting (CABG)...
January 25, 2019: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://read.qxmd.com/read/30745023/initial-intravascular-ultrasound-without-a-routine-early-baseline-study-in-the-evaluation-of-cardiac-transplant-vasculopathy-has-prognostic-valve
#2
Reza Arsanjani, Avinash Khitri, Mehrnoosh Hashemzadeh, Mohammad Reza Movahed
BACKGROUND: Abnormal minimal intimal thickening (MIT) on intravascular ultrasound (IVUS) defined as difference of ≥0.5 mm between baseline and one-year post-transplantation has been shown to have prognostic value. The goal of this retrospective cohort study was to evaluate whether abnormal MIT found on routine IVUS studies in cardiac transplant patients after 6 months without an early baseline study (modified MIT or MMIT), has any prognostic value. Furthermore, we evaluated the prognostic effect of serial IVUS performed beyond one year...
January 25, 2019: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://read.qxmd.com/read/30745059/saphenous-vein-graft-sacrifice-following-native-vessel-pci-is-safe-and-associated-with-favourable-longer-term-outcomes
#3
Simon J Wilson, Colm G Hanratty, Mark S Spence, Colum G Owens, Johannes Rigger, James C Spratt, Simon J Walsh
BACKGROUND: Competitive flow from saphenous vein grafts (SVG) that remain patent following percutaneous coronary intervention (PCI) of the native vessel may compromise durability of the reconstructed vessel. SVG sacrifice has been advocated, but the safety and longer-term outcomes of this are unknown. METHODS: We retrospectively reviewed all post-bypass patients who following successful PCI of the native vessel underwent attempted saphenous vein graft (SVG) closure between January 2014 and July 2018 in two institutions...
January 24, 2019: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://read.qxmd.com/read/30755362/comparison-in-prevalence-predictors-and-clinical-outcome-of-vsr-versus-fwr-after-acute-myocardial-infarction-the-prospective-multicenter-registry-moody-trial-heart-rupture-analysis
#4
Xianjun Xue, Jing Kan, Jun-Jie Zhang, Nailiang Tian, Fei Ye, Song Yang, Hong Qu, Shao-Liang Chen
BACKGROUND: Differences in the predictors between ventricular septal rupture (VSR) and free wall rupture (FWR) have not been fully studied. Data on the prevalence and clinical outcome of heart rupture are limited. HYPOTHESIS: This study aimed to investigate heart rupture incidence and clinical results in patients with acute myocardial infarction (AMI). METHODS: Of 9265 AMI patients in the MOODY registry between March 1999 and October 2016, a total of 146 were studied...
January 23, 2019: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://read.qxmd.com/read/30711476/impact-of-predilation-before-transcatheter-aortic-valve-implantation-with-new-generation-devices
#5
Arturo Giordano, Nicola Corcione, Paolo Ferraro, Alberto Morello, Sirio Conte, Francesco Bedogni, Luca Testa, Alessandro Iadanza, Gennaro Sardella, Massimo Mancone, Fabrizio Tomai, Giovanni De Persio, Tiziana Attisano, Martino Pepe, Giacomo Frati, Giuseppe Biondi-Zoccai
BACKGROUND: Significant aortic stenosis can be effectively treated with transcatheter aortic valve implantation (TAVI) in patients at high or intermediate surgical risk. Predilation is often performed to facilitate TAVI implantation, but its risk-benefit balance with new-generation devices is detabed. We aimed to appraise whether predilation is still needed with new-generation devices for TAVI. METHODS/MATERIALS: We queried the prospective multicenter RISPEVA (Registro Italiano GISE sull'impianto di Valvola Aortica Percutanea) Study, comparing patients with vs without predilation receiving Acurate, Evolut, Lotus, Portico, or Sapien3...
January 23, 2019: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://read.qxmd.com/read/30691780/sex-specific-predictors-of-mortality-following-balloon-aortic-valvuloplasty
#6
Navneet Sharma, Kathleen Stergiopoulos, Jie Yang, Donglei Yin, Puja B Parikh
BACKGROUND: A differential impact of sex has been observed in balloon aortic valvuloplasty (BAV) outcomes from small observational studies. Accordingly, we sought to compare mortality in men and women undergoing BAV and identify sex-specific predictors of mortality. METHODS: The Nationwide Inpatient Sample was screened for hospitalizations involving adults who underwent BAV between 2006 and 2014. Demographic data and clinical history were recorded. In-hospital mortality and predictors of death after BAV were assessed in men and women...
January 19, 2019: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://read.qxmd.com/read/30685339/safety-and-efficacy-of-stentablation-with-rotational-atherectomy-for-the-management-of-underexpanded-and-undilatable-coronary-stents
#7
Hoyle L Whiteside, Arun Nagabandi, Deepak Kapoor
INTRODUCTION: Coronary stent underexpansion is associated with in-stent restenosis and few interventions are available for the management of undilatable underexpanded stents. Stentablation (SA) with rotational atherectomy (RA) is a unique application and has previously been described with encouraging results. Data regarding SA is limited to case reports and small case series; therefore, reasonable concern persists regarding procedural safety and long-term outcomes. METHODS: This is a single-center retrospective study analyzing twenty consecutive patients who underwent SA with RA...
January 15, 2019: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://read.qxmd.com/read/30679117/outcomes-of-trans-radial-pci-compared-to-trans-femoral-pci-in-veterans-with-anemia-insight-from-the-va-clinical-assessment-reporting-and-tracking-cart-program
#8
Jayant Bagai, Edward Hess, William F Penny, Mary E Plomondon, Stephen W Waldo
BACKGROUND: Pre-procedural anemia is associated with increased bleeding and mortality post-percutaneous coronary intervention (PCI). The effect of trans-radial PCI (TR-PCI) in improving outcomes compared to trans-femoral PCI (TF-PCI) in anemic patients is not known. OBJECTIVE: The aim of this study was to evaluate the association between arterial access site (radial versus femoral) and outcomes in anemic Veterans undergoing PCI. METHODS: Patients with baseline anemia, undergoing PCI at Veterans Affairs (VA) facilities between 2009 and 2015, were divided into two groups based on primary radial or femoral access...
January 14, 2019: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://read.qxmd.com/read/30711477/how-should-we-treat-heavily-calcified-coronary-artery-disease-in-contemporary-practice-from-atherectomy-to-intravascular-lithotripsy
#9
REVIEW
George Kassimis, Tushar Raina, Nestoras Kontogiannis, Gopendu Patri, Joanna Abramik, Alex Zaphiriou, Adrian P Banning
Heavily calcified and densely fibrotic coronary lesions continue to represent a challenge for percutaneous coronary intervention (PCI), as they are difficult to dilate, and it is difficult to deliver and implant drug-eluting stents (DES) properly. Poor stent deployment is associated with high rates of periprocedural complications and suboptimal long-term clinical outcomes. Thanks to the introduction of several adjunctive PCI tools, like cutting and scoring balloons, atherectomy devices, and to the novel intravascular lithotripsy technology, the treatment of such lesions has become increasingly feasible, predictable and safe...
January 10, 2019: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://read.qxmd.com/read/30660497/orbiting-a-treatment-for-some-with-critical-hand-ischemia
#10
Ian C Gilchrist
No abstract text is available yet for this article.
January 10, 2019: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://read.qxmd.com/read/30745060/left-bundle-branch-block-after-transcatheter-aortic-valve-implantation-with-edwards-sapien-3-valve-influence-of-the-valve-depth-implantation
#11
Leire Unzué, Eulogio García, Belén Díaz-Antón, Francisco José Rodríguez-Rodrigo, Miguel Rodríguez Del Río, Rodrigo Teijeiro, Juan Medina, Francisco Javier Parra
OBJECTIVES: The aim of this study is to determine the relation between the valve depth implantation and the new-onset left bundle branch block (LBBB) in patients treated with transcatheter aortic valve implantation (TAVI) using Edwards Sapien 3 (S3) prosthesis. BACKGROUND: LBBB is the most common conduction disturbance after TAVI. The S3 has been associated with a higher incidence of LBBB. A deep valve implant could be related to new-onset LBBB with S3. METHODS: Seventy-six consecutive patients treated with transfemoral TAVI with S3 were included...
January 9, 2019: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://read.qxmd.com/read/30655010/transcatheter-closure-of-left-ventricular-apical-pseudoaneurysm-with-an-amplatzer-vascular-plug
#12
Francesco Negri, Carlo Cernetti, Luca Favero, Giuseppe Minniti, Alessandro De Leo, Giovanna De Simone, Gianfranco Sinagra
We report the case of a 66-year-old man, with a history of previous chest radiation therapy admitted to ED for heart failure. The patient was diagnosed with severe aortic stenosis and multivessel coronary disease and underwent surgical aortic valve replacement and coronary artery by pass grafts. Cardiac surgery was complicated by a left ventricular perforation by a venting catheter. The laceration was repaired with a Teflon patch apparently successful. Four months later, a CT scan performed for oncological follow-up demonstrated the complete detachment of the Teflon patch and the formation of a left ventricular pseudoaneurysm...
January 6, 2019: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://read.qxmd.com/read/30651214/in-complex-coronary-bifurcations-should-a-dedicated-stent-be-better-than-a-dedicated-approach
#13
Irene Pescetelli, Fabrizio Ricci, Marco Zimarino
No abstract text is available yet for this article.
January 6, 2019: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://read.qxmd.com/read/30651213/sirolimus-nanoparticles-delivering-a-new-hope-in-stentless-percutaneous-coronary-intervention
#14
Joshua P Loh, Hui Wen Sim
No abstract text is available yet for this article.
January 6, 2019: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://read.qxmd.com/read/30686620/feasibility-of-a-porcine-arteriovenous-shunt-model-for-assessment-of-acute-thrombogenicity-in-bifurcation-stenting-technique-by-optical-coherence-tomography
#15
Kazuhiro Dan, Hector M Garcia-Garcia, Evan Shlofmitz, Takayuki Okamura, Kayode O Kuku, David Hellinga, Frank D Kolodgie, Alexandre Hideo-Kajita, Sameer Desale, Ron Waksman
BACKGROUND: Double kissing (DK) crush stenting has been reported as a superior bifurcation stenting strategy compared to culotte stenting. However, the mechanism associated with the reduction of clinical events by DK crush stenting remains unclear. We therefore investigated the thrombogenicity of DK crush stenting and culotte stenting with both bare-metal stents (BMS) and drug-eluting stents (DES) and the feasibility of a novel porcine arteriovenous shunt model. METHODS: High-resolution intracoronary imaging with optical coherence tomography (OCT) evaluated the bifurcation stenting models for thrombogenicity...
January 4, 2019: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://read.qxmd.com/read/30638890/transcatheter-versus-surgical-aortic-valve-replacement-in-low-risk-surgical-patients-a-meta-analysis-of-randomized-clinical-trials
#16
Babikir Kheiri, Mohammed Osman, Hossam Abubakar, Ahmed Subahi, Adam Chahine, Sahar Ahmed, Ghassan Bachuwa, Mohammad L Alkotob, Mustafa Hassan, Deepak L Bhatt
BACKGROUND: Transcatheter aortic valve replacement (TAVR) is a valid option for patients with high or intermediate surgical risk. However, clinical outcomes of TAVR in low-risk patients are lacking. Our aim was to evaluate the efficacy and safety of TAVR versus surgical aortic valve replacement (SAVR) in low-surgical-risk patients. METHODS: Electronic database review was conducted for all randomized clinical trials (RCTs) that compared TAVR versus SAVR in low-risk patients...
January 4, 2019: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://read.qxmd.com/read/30683562/the-relation-between-optical-coherence-tomography-detected-layered-pattern-and-acute-side-branch-occlusion-after-provisional-stenting-of-coronary-bifurcation-lesions
#17
Yang Cao, Gary S Mintz, Mitsuaki Matsumura, Wenbin Zhang, Yongqing Lin, Xiao Wang, Akiko Fujino, Tetsumin Lee, Tadashi Murai, Masahiro Hoshino, Eisuke Usui, Yoshihisa Kanaji, Taishi Yonetsu, Tsunekazu Kakuta, Akiko Maehara
BACKGROUND/PURPOSE: Layered pattern (presumed to be healed plaque after a thrombotic event) can be observed by optical coherence tomography (OCT). We sought to assess the ability of OCT-detected plaque composition to predict acute side branch (SB) occlusion after provisional bifurcation stenting. METHODS: This is a retrospective observational study using pre-intervention OCT in the main vessel to predict Thrombolysis in Myocardial Infarction (TIMI) flow grade ≤1 in a SB (diameter ≥ 1...
December 28, 2018: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://read.qxmd.com/read/30685340/role-of-intracoronary-fibrinolytic-therapy-in-contemporary-pci-practice
#18
REVIEW
Sanjeev Kumar Agarwal, Shubham Agarwal
Plaque rupture or plaque erosion leads to intracoronary thrombus formation resulting in coronary artery occlusion and ST-segment elevation myocardial infarction. Early restoration of blood flow in occluded coronary artery is the mainstay of therapy and it can be achieved by either thrombolytic therapy or primary percutaneous coronary intervention (P-PCI) or a combination of these two in many different ways. It has been proved that primary PCI is better than thrombolytic therapy in establishing early and effective recanalization of infarct related artery, reducing major adverse cardiovascular events (MACE) and increasing survival...
December 27, 2018: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://read.qxmd.com/read/30626544/hdl-3-c-is-a-marker-of-coronary-artery-disease-severity-and-inflammation-in-patients-on-statin-therapy
#19
Rahul Chaudhary, Marija Kinderytė, Rohit Chaudhary, Ajaypaul Sukhi, Kevin Bliden, Udaya Tantry, Paul Gurbel
INTRODUCTION: Low high-density lipoprotein (HDL-C) and inflammation are risk factors for coronary artery disease (CAD). However, limited data are available determining the role of HDL-C sub-particles HDL2 -C and HDL3 -C for assessing CAD severity in patients on statin therapy. METHODS: Blood samples were obtained prior to cardiac catheterization in 304 consecutive patients with suspected CAD on statin therapy in this sub-analysis of Multi-Analyte, thrombogenic, and Genetic Markers of Atherosclerosis (MAGMA, NCT01276678) study...
December 27, 2018: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://read.qxmd.com/read/30638891/culprit-vessel-only-versus-multivessel-percutaneous-coronary-intervention-in-acute-myocardial-infarction-with-cardiogenic-shock-a-systematic-review-and-meta-analysis
#20
Muhammad Faisal Khalid, Abdul Ahad Khan, Furqan Khattak, Muhammad Talha Ayub, Jayant Bagai, Debabrata Mukherjee, Thomas Helton, Mauricio G Cohen, Subhash Banerjee, Timir K Paul
BACKGROUND: Previous studies comparing outcomes between culprit vessel only percutaneous coronary intervention (CV-PCI) versus multivessel percutaneous coronary intervention (MV-PCI) in patients with cardiogenic shock in the setting of acute myocardial infarction have shown conflicting results. This meta-analysis investigates the optimal approach for management of these patients considering recently published data. METHODS: Electronic databases including MEDLINE, ClinicalTrials...
December 21, 2018: Cardiovascular Revascularization Medicine: Including Molecular Interventions
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