journal
https://read.qxmd.com/read/38963341/predictive-values-of-pre-treatment-brain-age-models-to-rtms-effects-in-neurocognitive-disorder-with-depression-secondary-analysis-of-a-randomised-sham-controlled-clinical-trial
#1
RANDOMIZED CONTROLLED TRIAL
Hanna Lu, Jing Li, Sandra Sau Man Chan, Suk Ling Ma, Vincent Chung Tong Mok, Lin Shi, Arthur Dun-Ping Mak, Linda Chiu Wa Lam
INTRODUCTION: One major challenge in developing personalised repetitive transcranial magnetic stimulation (rTMS) is that the treatment responses exhibited high inter-individual variations. Brain morphometry might contribute to these variations. This study sought to determine whether individual's brain morphometry could predict the rTMS responders and remitters. METHODS: This was a secondary analysis of data from a randomised clinical trial that included fifty-five patients over the age of 60 with both comorbid depression and neurocognitive disorder...
2024: Dialogues in Clinical Neuroscience
https://read.qxmd.com/read/38837043/the-impact-of-testosterone-lowering-medication-on-recidivism-in-individuals-convicted-of-sexual-offenses
#2
JOURNAL ARTICLE
Julia Sauter, Laura M Lingenti, Martin Rettenberger, Daniel Turner, Peer Briken, Tatjana Voß
INTRODUCTION: Treatment of individuals who have committed sexual offences with Testosterone-Lowering Medication (TLM) is a comparatively intrusive kind of intervention, which regularly takes place in coercive contexts. Thus, the question of efficacy, but also the question of who should be treated, when and for how long, are of great importance. METHODS: Recidivism rates of TLM-treated high-risk individuals (+TLM; n  = 54) were compared with high-risk individuals treated with psychotherapy only in the same forensic outpatient clinic (-TLM; n  = 79)...
2024: Dialogues in Clinical Neuroscience
https://read.qxmd.com/read/38829782/microcephaly-type-22-and-autism-spectrum-disorder-a-case-report-and-review-of-literature
#3
REVIEW
Jiqiang Ma, Yu'e Liu, Kaijun Zhao
INTRODUCTION: Autism Spectrum Disorder (ASD) is a complex neurodevelopmental disorder with a multifaceted etiology. This case report explores the ischemic cryptogenic vascular dissection as a potential underlying cause of ASD. METHODS: A 9-year-old child presented with symptoms of ASD, including social interaction difficulties, repetitive behaviors, and cognitive challenges. Despite conventional ASD treatments, significant improvement was only observed after addressing an underlying ischemic cryptogenic vascular dissection identified through DCE-CT...
2024: Dialogues in Clinical Neuroscience
https://read.qxmd.com/read/38767966/a-global-neuronal-workspace-model-of-functional-neurological-disorders
#4
REVIEW
Lionel Naccache, Esteban Munoz-Musat
We introduce here a general model of Functional Neurological Disorders based on the following hypothesis: a Functional Neurological Disorder could correspond to a consciously initiated voluntary top-down process causing involuntary lasting consequences that are consciously experienced and subjectively interpreted by the patient as involuntary. We develop this central hypothesis according to Global Neuronal Workspace theory of consciousness, that is particularly suited to describe interactions between conscious and non-conscious cognitive processes...
2024: Dialogues in Clinical Neuroscience
https://read.qxmd.com/read/37994794/urbanicity-and-psychotic-disorders-facts-and-hypotheses
#5
REVIEW
Baptiste Pignon, Andrei Szöke, Benson Ku, Maria Melchior, Franck Schürhoff
In the present qualitative literature review, we summarise data on psychotic disorders and urbanicity, focusing particularly on recent findings. Longitudinal studies of the impact of urbanicity on the risk for psychotic disorders have consistently shown a significant association, with a relative risk between 2 and 2.5. However, most of the original studies were conducted in Western Europe, and no incidence studies were conducted in low- and middle-income countries. European studies suggest that neighbourhood-level social fragmentation and social capital may partly explain this association...
December 2023: Dialogues in Clinical Neuroscience
https://read.qxmd.com/read/37916739/neural-correlates-of-negative-life-events-and-their-relationships-with-alcohol-and-cannabis-use-initiation
#6
JOURNAL ARTICLE
Yihong Zhao, Marc N Potenza, Susan F Tapert, Martin P Paulus
OBJECTIVE: Negative life events (NLEs), e.g., poor academic performance (controllable) or being the victim of a crime (uncontrollable), can profoundly affect the trajectory of one's life. Yet, their impact on how the brain develops is still not well understood. This investigation examined the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA) dataset for the impact of NLEs on the initiation of alcohol and cannabis use, as well as underlying neural mechanisms. METHODS: This study evaluated the impact of controllable and uncontrollable NLEs on substance use initiation in 207 youth who initiated alcohol use, 168 who initiated cannabis use, and compared it to 128 youth who remained substance-naïve, using generalised linear regression models...
December 2023: Dialogues in Clinical Neuroscience
https://read.qxmd.com/read/37837439/an-overview-of-the-use-of-psychoactive-substances-among-students-at-the-university-of-lille-during-the-covid-19-health-crisis-results-of-the-petra-study
#7
JOURNAL ARTICLE
Louise Carton, Axel Bastien, Nathalie Chérot, Clément Caron, Sylvie Deheul, Olivier Cottencin, Sophie Gautier, Sophie Moreau-Crépeaux, Thibaut Dondaine, Régis Bordet
OBJECTIVES: Students represent a population at risk for substance abuse. That risk may have been exacerbated by the COVID-19 pandemic. We aimed to describe substance abuse among students and to compare consumption according to the university field. METHODS: A self-administered questionnaire was sent by email to all students at the University of Lille, France, between March and July 2021. This anonymous questionnaire included questions about sociodemographic characteristics, university courses and the use of psychoactive substances (frequency, reasons, routes of administration) since the first university year...
December 2023: Dialogues in Clinical Neuroscience
https://read.qxmd.com/read/37796239/current-pharmacotherapy-approaches-and-novel-gabaergic-antidepressant-development-in-postpartum-depression
#8
REVIEW
Sara V Carlini, Lauren M Osborne, Kristina M Deligiannidis
Postpartum depression has deleterious effects on childbearing persons globally. Existing treatments have been largely extrapolated from those for other forms of depression and have included pharmacotherapy, psychotherapy, and neuromodulation. Hormonal treatments with oestrogen and progestogens, thought to be a rational approach to treatment in response to an emerging literature on the pathophysiology of postpartum depression, have only limited evidence for efficacy to date. Novel antidepressant development with allopregnanolone analogues, in contrast, has proven a promising avenue for the development of rationally designed and efficacious treatments...
December 2023: Dialogues in Clinical Neuroscience
https://read.qxmd.com/read/37594217/neural-mechanisms-linked-to-treatment-outcomes-and-recovery-in-substance-related-and-addictive-disorders
#9
REVIEW
Gemma Mestre-Bach, Marc N Potenza
The present review focuses on potential neural mechanisms underlying recovery from psychiatric conditions characterised by impaired impulse control, specifically substance use disorders, gambling disorder, and internet gaming disorder. Existing treatments (both pharmacological and psychological) for these addictions may impact brain processes, and these have been evaluated in neuroimaging studies. Medication challenge and short-term intervention administration will be considered with respect to treatment utility...
December 2023: Dialogues in Clinical Neuroscience
https://read.qxmd.com/read/37497602/independent-effects-of-posttraumatic-stress-disorder-diagnosis-and-metabolic-syndrome-status-on-prefrontal-cortical-thickness-and-subcortical-gray-matter-volumes
#10
JOURNAL ARTICLE
Hilmar Klaus Luckhoff, Stefan du Plessis, Heuvel Leigh van den, Robin Emsley, Soraya Seedat
INTRODUCTION: Posttraumatic stress disorder (PTSD) and metabolic syndrome (MetS) are associated with overlapping brain structural differences. These often involve brain structures involved in the regulation of appetite, food intake, satiety, and reward processing. We examined the individual and interactive effects of PTSD diagnosis and MetS on cortical thickness and subcortical gray matter volumes in patients with PTSD ( n  = 104) compared to trauma-exposed controls ( n  = 97)...
December 2023: Dialogues in Clinical Neuroscience
https://read.qxmd.com/read/37427882/suicidality-risk-after-using-cannabis-and-cannabinoids-an-umbrella-review
#11
REVIEW
Ahmad Shamabadi, Ali Ahmadzade, Kasra Pirahesh, Alireza Hasanzadeh, Hassan Asadigandomani
The increasing prevalence and burden of suicide have led to numerous studies to identify its risk factors. Cannabis is the most common illicit substance detected in suicide victims' toxicology tests. This study aims to identify and appraise systematic reviews investigating suicidality after using cannabis and cannabinoids. Seven databases and two registries were searched without restrictions for systematic reviews investigating cannabis effects on suicidality. AMSTAR-2 was used for quality assessment and corrected covered area and citation matrix were used to determine overlap...
December 2023: Dialogues in Clinical Neuroscience
https://read.qxmd.com/read/37390849/polysomnographic-parameters-in-long-covid-chronic-insomnia-patients
#12
JOURNAL ARTICLE
Alexandre Rouen, Jonathan Taïeb, Gabriela Caetano, Victor Pitron, Maxime Elbaz, Dominique Salmon, Damien Leger
INTRODUCTION: While COVID-19 is predominantly considered to be an acute self-remitting disease, it has been pointed out that a variety of symptoms can linger for several months, a phenomenon identified as long-COVID. Insomnia is particularly prevalent in long-COVID. In the present study, we aimed at confirming and characterising insomnia in long-COVID patients through polysomnography and to identify whether its parameters differ from patients with chronic insomnia and no long-COVID history...
December 2023: Dialogues in Clinical Neuroscience
https://read.qxmd.com/read/37190759/connectome-based-prediction-of-craving-in-gambling-disorder-and-cocaine-use-disorder
#13
JOURNAL ARTICLE
Stephanie Antons, Sarah W Yip, Cheryl M Lacadie, Javid Dadashkarimi, Dustin Scheinost, Matthias Brand, Marc N Potenza
INTRODUCTION: Craving, involving intense and urgent desires to engage in specific behaviours, is a feature of addictions. Multiple studies implicate regions of salience/limbic networks and basal ganglia, fronto-parietal, medial frontal regions in craving in addictions. However, prior studies have not identified common neural networks that reliably predict craving across substance and behavioural addictions. METHODS: Functional magnetic resonance imaging during an audiovisual cue-reactivity task and connectome-based predictive modelling (CPM), a data-driven method for generating brain-behavioural models, were used to study individuals with cocaine-use disorder and gambling disorder...
December 2023: Dialogues in Clinical Neuroscience
https://read.qxmd.com/read/36924413/effects-of-intermittent-theta-burst-transcranial-magnetic-stimulation-on-cognition-and-hippocampal-volumes-in-bipolar-depression
#14
RANDOMIZED CONTROLLED TRIAL
Ivan J Torres, Ruiyang Ge, Alexander McGirr, Fidel Vila-Rodriguez, Sharon Ahn, Jayasree Basivireddy, Nazlin Walji, Sophia Frangou, Raymond W Lam, Lakshmi N Yatham
INTRODUCTION: Repetitive transcranial magnetic stimulation (TMS) is increasingly used to treat neurocognitive symptoms in mood disorders. Intermittent theta burst stimulation (iTBS) is a brief version of TMS that may preferentially target cognitive functions. This study evaluated whether iTBS leads to cognitive improvements and associated increased hippocampal volumes in bipolar depression. METHODS: In a two-site double-blind randomised sham controlled trial (NCT02749006), 16 patients received active iTBS to the Left Dorsolateral Prefrontal Cortex (DLPF) and 15 patients received sham stimulation across four weeks...
December 2023: Dialogues in Clinical Neuroscience
https://read.qxmd.com/read/36817972/independent-component-analysis-for-internet-gaming-disorder
#15
REVIEW
Gemma Mestre-Bach, Roser Granero, Fernando Fernández-Aranda, Susana Jiménez-Murcia, Marc N Potenza
Introduction: There is a growing interest in the study of the neurobiological correlates of internet gaming disorder (IGD), and new techniques are beginning to be implemented for this purpose, such as independent component analysis (ICA). Aims: The present narrative review aimed to explore the studies that had used ICA for the study of the different brain networks possibly associated with IGD. Methods: We specifically focussed on three of the main networks: default-mode network, executive-control and salience networks...
2023: Dialogues in Clinical Neuroscience
https://read.qxmd.com/read/36698618/exercise-addiction-a-narrative-overview-of-research-issues
#16
REVIEW
Aviv Weinstein, Attila Szabo
This narrative overview summarises the work on exercise addiction (EA) over the past 12 years and exposes critical conceptual and methodological issues. More than 1000 articles exist on EA, conceptualised as uncontrolled training harming the individual. Still, EA has no clinical diagnosis criteria at this time. Research is increasing continuously, but it is stale in advancing knowledge. Scalar measurement and lack of differentiation between addictive and instrumental exercise could be reasons for insufficient progress...
2023: Dialogues in Clinical Neuroscience
https://read.qxmd.com/read/37522807/the-world-federation-of-societies-of-biological-psychiatry-guidelines-on-the-assessment-and-pharmacological-treatment-of-compulsive-sexual-behaviour-disorder
#17
JOURNAL ARTICLE
Daniel Turner, Peer Briken, Joshua Grubbs, Leo Malandain, Gemma Mestre-Bach, Marc N Potenza, Florence Thibaut
OBJECTIVES: The current guidelines aim to evaluate the role of pharmacological agents in the treatment of patients with compulsive sexual behaviour disorder (CSBD). They are intended for use in clinical practice by clinicians who treat patients with CSBD. METHODS: An extensive literature search was conducted using the English-language-literature indexed on PubMed and Google Scholar without time limit, supplemented by other sources, including published reviews. RESULTS: Each treatment recommendation was evaluated with respect to the strength of evidence for its efficacy, safety, tolerability, and feasibility...
December 2022: Dialogues in Clinical Neuroscience
https://read.qxmd.com/read/36246995/cardiac-vagal-activity-is-associated-with-gut-microbiome-patterns-in-women-an-exploratory-pilot-study
#18
JOURNAL ARTICLE
Sabrina Mörkl, Andreas Oberascher, Josef M Tatschl, Sonja Lackner, Thomaz F S Bastiaanssen, Mary I Butler, Maximilian Moser, Matthias Frühwirth, Harald Mangge, John F Cryan, Timothy G Dinan, Sandra J Holasek
INTRODUCTION: A functional reciprocity between the gut microbiome and vagal nerve activity has been suggested, however, human studies addressing this phenomenon are limited. METHODS: Twenty-four-hour cardiac vagal activity (CVA) was assessed from 73 female participants (aged 24.5 ± 4.3 years). Additionally, stool samples were subjected to 16SrRNA gene analysis (V1-V2). Quantitative Insights Into Microbial Ecology (QIIME) was used to analyse microbiome data...
2022: Dialogues in Clinical Neuroscience
https://read.qxmd.com/read/35860177/graph-theory-in-paediatric-epilepsy-a-systematic-review
#19
REVIEW
Raffaele Falsaperla, Giovanna Vitaliti, Simona Domenica Marino, Andrea Domenico Praticò, Janette Mailo, Michela Spatuzza, Maria Roberta Cilio, Rosario Foti, Martino Ruggieri
Graph theoretical studies have been designed to investigate network topologies during life. Network science and graph theory methods may contribute to a better understanding of brain function, both normal and abnormal, throughout developmental stages. The degree to which childhood epilepsies exert a significant effect on brain network organisation and cognition remains unclear. The hypothesis suggests that the formation of abnormal networks associated with epileptogenesis early in life causes a disruption in normal brain network development and cognition, reflecting abnormalities in later life...
2021: Dialogues in Clinical Neuroscience
https://read.qxmd.com/read/35860176/translational-chasm-and-dialogues-in-clinical-neuroscience
#20
EDITORIAL
Lakshmi N Yatham, Florence Thibaut
No abstract text is available yet for this article.
2021: Dialogues in Clinical Neuroscience
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