journal
https://read.qxmd.com/read/38949853/elp-protocol-an-original-approach-for-the-mitigation-of-anti-cd38-interference
#1
JOURNAL ARTICLE
Erica Maiorana, Maria Bortolati, Steluta Croitoru, Gledis Llanaj, Cinzia Ongaro, Eva Polga, Melissa Salvo, Alessandra Sandini, Krizia Succoli, Tiziana Tortomasi, Giacomina Vicino, Francesco Fiorin
BACKGROUND: Transfusion medicine is facing new challenges from therapies which interfere with pre-transfusional tests, such as monoclonal antibodies targeting blood-cell antigens. Anti-CD38 monoclonal antibodies, widely used to treat multiple myeloma, cause panreactivity of indirect antiglobulin test; this can be resolved by treating cells with dithiothreitol to disrupt the CD38 disulphide bonds expressed on red blood cell surfaces. Interference mitigation strategy with dithiothreitol, however, has some drawbacks: it entails losing the traceability of results and the denaturation of blood group systems sensitive to reducing agents; it takes time to perform and quality controls are lost...
June 26, 2024: Blood Transfusion
https://read.qxmd.com/read/38949849/severe-breakthrough-hemolysis-during-compassionate-use-of-pegcetacoplan-in-paroxysmal-nocturnal-hemoglobinuria-managing-an-emergency
#2
JOURNAL ARTICLE
Elisabetta Metafuni, Antonella Carbone, Luca Petriccione, Sabrina Giammarco, Maria A Limongiello, Silvia Bellesi, Patrizia Chiusolo, Simona Sica
No abstract text is available yet for this article.
June 23, 2024: Blood Transfusion
https://read.qxmd.com/read/38949852/severe-aplastic-anemia-secondary-to-immune-checkpoint-inhibitor-case-report-and-literature-review
#3
JOURNAL ARTICLE
Alessandro Bosi, Maria C Di Chio, Marta Bortolotti, Giorgio A Croci, Francesco Passamonti, Wilma Barcellini, Bruno Fattizzo
No abstract text is available yet for this article.
June 12, 2024: Blood Transfusion
https://read.qxmd.com/read/38949850/analysis-of-hla-matching-between-deceased-organ-donors-and-cord-blood-units-from-a-national-bank-network-as-a-basis-for-potential-platforms-for-chimerism-based-immune-tolerance-after-solid-organ-transplantation
#4
JOURNAL ARTICLE
Roberto Crocchiolo, Letizia Lombardini, Nicoletta Sacchi, Ilaria Lombardi, John Blake, David Allan, Mohamad Sobh, Francesca Puoti, Silvia Trapani, Anna Maria Gallina, Marco Sacchi, Simonetta Pupella, Paola Bergamaschi, Silvano Rossini, Massimo Cardillo
No abstract text is available yet for this article.
June 10, 2024: Blood Transfusion
https://read.qxmd.com/read/38949851/a-case-of-trisomy-9-with-mixed-field-abo-blood-type
#5
JOURNAL ARTICLE
Sena Fujii, Yuji Shimura, Keiichi Shigehara, Yuji Sasada, Tohru Inaba
No abstract text is available yet for this article.
June 7, 2024: Blood Transfusion
https://read.qxmd.com/read/38949848/no-evidence-for-liberal-transfusion-in-acute-myocardial-infarction
#6
JOURNAL ARTICLE
Aryeh Shander, Kevin M Trentino, Caroline Evans, John G F Cleland
No abstract text is available yet for this article.
June 7, 2024: Blood Transfusion
https://read.qxmd.com/read/38814885/45%C3%A2-convegno-nazionale-di-studi-di-medicina-trasfusionale-rimini-29-31-maggio-2024
#7
JOURNAL ARTICLE
Francesco Fiorin, Patrizia Di Gregorio, Pierluigi Berti, Antonella Matteocci, Giorgio Gandini, Serelina Coluzzi, Renato Messina, Silvano Rossini, Gianluca Ubezio, Domenico Visceglie, Giuseppe Aprili
No abstract text is available yet for this article.
May 29, 2024: Blood Transfusion
https://read.qxmd.com/read/38814880/sars-cov-2-infection-rebound-among-patients-receiving-antiviral-agents-convalescent-plasma-or-no-treatment-a-systematic-review-with-meta-analysis
#8
REVIEW
Mario Cruciani, Ilaria Pati, Francesca Masiello, Vanessa Piccinini, Simonetta Pupella, Vincenzo De Angelis
BACKGROUND: There is some evidence showing rebound of COVID-19 infections in patients treated with nirmatrelvir-ritonavir between 2 and 8 days following cessation of the antiviral treatment. COVID-19 rebound is not unique to patients treated with nirmatrelvir-ritonavir, but is also observed in molnupiravir recipients, in patients who did not receive any antiviral treatment and in patients who received convalescent plasma (CP). MATERIALS AND METHODS: This was a systematic review with meta-analysis of clinical trials evaluating rates of virologic and clinical rebound in COVID-19 patients receiving antiviral agents, CP or no treatment...
May 27, 2024: Blood Transfusion
https://read.qxmd.com/read/38814878/description-of-the-first-case-of-c-137-8c-t-gypb-mutation-not-associated-to-the-gypb-p2-allele
#9
LETTER
Luca Collodel, Tommaso Mancuso, Gialuca Gessoni
No abstract text is available yet for this article.
May 23, 2024: Blood Transfusion
https://read.qxmd.com/read/38814884/assessing-the-risk-of-transfusion-transmitted-variant-creutzfeldt-jakob-disease-an-european-perspective
#10
JOURNAL ARTICLE
Dragoslav Domanović, Antoine Lewin, Peter O'Leary, Tiziana Janner-Jametti, Soraya Amar El Dusouqui, Ana Paula Sousa, Hans Zaaijer, Barnaby Roberts, Daisy Bougard, Daniele Prati, Jonas Nordberg, Christian Erikstrup, Mart Janssen, Ryanne Lieshout-Krikke, Knut Gubbe, Niamh O'Flaherty, Genevieve Mathy, Andrée-Marie Chantillon, Riikka Lehtisalo, Øfsteng H Sørensen, Pierre Tiberghien, Stephen Thomas
Several countries have recently reassessed the international risk of variant Creutzfeldt-Jakob disease (vCJD) transmission through transfusion of blood and blood components (red blood cells, platelets and plasma) and relaxed donor deferrals based on geographic and transfusion exposure in countries formerly considered to be high risk, such as the UK. In this regard, the European Blood Alliance organised a consensus meeting of experts and involved professionals to discuss current knowledge, epidemiological data, prevention and various methods for assessing the risk of transfusion-transmitted vCJD, as well as to develop an appropriate position on possible approaches to address these challenges in Europe...
May 16, 2024: Blood Transfusion
https://read.qxmd.com/read/38814883/ultraviolet-light-and-riboflavin-accelerates-red-blood-cell-dysfunction-in-vitro-and-in-a-guinea-pig-transfusion-model
#11
JOURNAL ARTICLE
Jin Hyen Baek, Hye Kyung H Shin, Fei Xu, Xiaoyuan Zhang, Matthew C Williams, Yamei Gao, Jaroslav G Vostal, Paul W Buehler, Carlos Villa, Felice D'Agnillo
BACKGROUND: Quality assessment of modified or processed red blood cell (RBC) components, such as pathogen-reduced RBCs, using only in vitro testing may not always be predictive of in vivo performance. Mouse or rat in vivo models are limited by a lack of applicability to certain aspects of human RBC biology. Here, we used a guinea pig model to study the effects of riboflavin combined with UV light on the integrity of RBCs in vitro and following transfusion in vivo. MATERIALS AND METHODS: Guinea pig RBCs were collected from whole blood (WB) treated with varying UV doses (10, 20, 40 or 80 J/mL) in the presence of riboflavin (UVR-RBCs)...
May 15, 2024: Blood Transfusion
https://read.qxmd.com/read/38814882/blood-transfusion-associated-anaphylaxis-in-perioperative-and-non-perioperative-patients-in-western-norway-2002-2021
#12
JOURNAL ARTICLE
Bjarte Skoe Erikstein, Marie Bjørbak Alnæs, Torunn Oveland Apelseth
BACKGROUND: Anaphylaxis after blood transfusion is a feared complication accounting for severe morbidity. A retrospective study was performed at Haukeland University Hospital, Bergen, Norway, to investigate the rate and features of transfusion-associated anaphylaxis (TAA) occurring between 2002-2021. MATERIALS AND METHODS: Identified cases of TAA were studied by an immunologist and an allergist to extract information about general characteristics, amplifying factors, co-morbidity, treatment, and treatment responses...
May 15, 2024: Blood Transfusion
https://read.qxmd.com/read/38814879/navigating-anemia-and-anticoagulation-in-elderly-patients-undergoing-orthopedic-surgery-strategies-for-preventing-complications-and-implementing-treatments
#13
REVIEW
Elvira Grandone, Giovanni L Tiscia, Angelo Ostuni, Francesco Marongiu, Doris Barcellona
BACKGROUND: Elderly populations face an increased risk of anemia, leading to elevated transfusion requirements during surgery, especially major orthopedic procedures. Anemia itself increases the risk of thromboembolic events, thus compounding complications in elderly individuals. Polypharmacy and the prevalent use of oral anticoagulants (OAC), particularly for atrial fibrillation, contribute to bleeding risks in this population. Data available in the literature on the peri-operative management of anemia in patients taking OAC is limited and often heterogeneous...
May 6, 2024: Blood Transfusion
https://read.qxmd.com/read/38814881/single-exon-fetal-rhd-genotyping-a-31-month-follow-up-in-the-obstetric-population-of-western-sweden
#14
JOURNAL ARTICLE
Cecilia Pardi, Åsa Hellberg, Pauline Isakson
BACKGROUND: The Rh blood group system is highly complex, polymorphic, and immunogenic. The presence of RHD gene variants in RhD negative pregnant women is a challenge in fetal RHD genotyping as it may influence the antenatal management of anti-D prophylaxis. The aim of this study was to determine the efficiency of a non-invasive single-exon approach in the obstetric population of Western Sweden in a 31-month follow up. The frequency and type of maternal RHD variants were explored and the relation to the ethnicity was elucidated...
April 23, 2024: Blood Transfusion
https://read.qxmd.com/read/38709672/defining-the-breakpoints-of-hybrid-blood-group-alleles
#15
LETTER
Gregory A Denomme
No abstract text is available yet for this article.
May 2024: Blood Transfusion
https://read.qxmd.com/read/38557318/thrombotic-thrombocytopenic-purpura-optimal-management-of-plasma-exchange-platelets-and-infection-prevention
#16
REVIEW
Ingrid Parra-Salinas, Juan Rodríguez-García, Saioa Zalba-Marcos, José A García-Erce
No abstract text is available yet for this article.
May 2024: Blood Transfusion
https://read.qxmd.com/read/38557321/a-survey-on-the-implementation-of-patient-blood-management-programs-in-italy
#17
JOURNAL ARTICLE
Vanessa Agostini, Francesca Masiello, Stefania Vaglio, Eva Veropalumbo, Ursula La Rocca, Simonetta Pupella, Vincenzo De Angelis
BACKGROUND: Since 2012, in line with the World Health Organization (WHO) resolution WHA63.12 of 05/21/2010, the Italian National Blood Center has been promoting patient blood management (PBM). In order to verify the level of PBM implementation nationwide, we submitted a survey to all healthcare providers. MATERIAL AND METHODS: In line with what was proposed in the international scientific literature in the field, a series of indicators were used derived from the four main blocks related to PBM strategies: the management of patient anemia; the optimization of hemostasis; blood conservation strategies; patient-centred decision-making...
March 28, 2024: Blood Transfusion
https://read.qxmd.com/read/38557324/development-and-evaluation-of-trigger-tools-to-identify-pediatric-blood-management-errors
#18
JOURNAL ARTICLE
Swaminathan Kandaswamy, Cassandra D Josephson, Margo R Rollins, Jennifer Jones, Patricia Zerra, Ruchika Goel, Jennifer Andrews, Jeanne E Hendrickson, Lani Lieberman, Evan W Orenstein
BACKGROUND: Pediatric patient blood management (PBM) programs require continuous surveillance of errors and near misses. However, most PBM programs rely on passive surveillance methods. Our objective was to develop and evaluate a set of automated trigger tools for active surveillance of pediatric PBM errors. MATERIALS AND METHODS: We used the Rand-UCLA method with an expert panel of pediatric transfusion medicine specialists to identify and prioritize candidate trigger tools for all transfused blood products...
March 27, 2024: Blood Transfusion
https://read.qxmd.com/read/38557319/why-might-cord-blood-be-a-better-source-of-platelets-for-transfusion-to-neonates
#19
REVIEW
Valeria Cortesi, Giacomo Cavallaro, Genny Raffaeli, Stefano Ghirardello, Fabio Mosca, Thomas R L Klei, Suzanne Fustolo-Gunnink, Simon Stanworth, Helen V New, Emöke Deschmann, Enrico Lopriore
Thrombocytopenia (defined as a platelet count <150×109 /L) is a common condition in preterm neonates and may occur in 18-35% of all infants admitted to the Neonatal Intensive Care Unit (NICU). Neonatal platelet functionality in terms of reactivity is often described as reduced compared to adults, even in healthy, term neonates. However, this platelet "hyporeactivity" does not correspond to a global functional impairment of the normal delicately balanced neonatal hemostatic system. The extent to which neonatal thrombocytopenia and platelet hyporeactivity contribute to the bleeding risk in preterm neonates remains unknown...
March 27, 2024: Blood Transfusion
https://read.qxmd.com/read/38557326/patients-with-red-cell-antibodies-registries-improve-patient-care-by-increasing-patient-safety-reducing-costs-and-enabling-health-information-exchange
#20
EDITORIAL
Willy Albert Flegel
No abstract text is available yet for this article.
March 15, 2024: Blood Transfusion
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