Richard D Urman, Diane L Seger, Julie M Fiskio, Bridget A Neville, Elizabeth M Harry, Scott G Weiner, Belinda Lovelace, Randi Fain, Jessica Cirillo, Jeffrey L Schnipper
OBJECTIVE: Opioid analgesics are a mainstay for acute pain management, but postoperative opioid administration has risks. We examined the prevalence, risk factors, and consequences of opioid-related adverse drug events (ORADEs) in a previously opioid-free surgical population. METHODS: A retrospective, observational, cohort study using administrative, billing, clinical, and medication administration data from two hospitals. Data were collected for all adult patients who were opioid-free at admission, underwent surgery between October 1, 2015, and September 30, 2016, and received postoperative opioids...
January 21, 2019: Journal of Patient Safety