Jérôme Devoy, Souhail Al-Abed, Benjamin Cerdan, Wan-Seob Cho, David Dubuc, Emmanuel Flahaut, Katia Grenier, Stéphane Grossmann, Mary Gulumian, Jiyoung Jeong, Boo Wook Kim, Adam Laycock, Jong Seong Lee, Rachel Smith, Mei Yang, Il Je Yu, Minfang Zhang, Frédéric Cosnier
Carbon nanotubes (CNTs) are increasingly being used in industrial applications, but their toxicological data in animals and humans are still sparse. To assess the toxicological dose-response of CNTs and to evaluate their pulmonary biopersistence, their quantification in tissues, especially lungs, is crucial. There are currently no reference methods or reference materials for low levels of CNTs in organic matter. Among existing analytical methods, few have been fully and properly validated. To remedy this, we undertook an inter-laboratory comparison on samples of freeze-dried pig lung, ground and doped with CNTs...
April 1, 2024: Nanotoxicology