Journal of Clinical Sleep Medicine : JCSM : Official Publication of the American Academy of Sleep Medicine

STUDY OBJECTIVES: We aimed to investigate the use of sleep efficiency (SE) as a measure of sleep disturbance in infants and toddlers with ABI and evaluate associations between SE and child health related quality of life (HRQOL) and family outcomes. METHODS: Retrospective cohort study of 101 children aged 3-36 months who survived critical care for ABI. SE was quantified from the Brief Infant Sleep Questionnaire as a ratio of nighttime sleep to total time in bed; poor SE defined as <80%...

STUDY OBJECTIVES: A new-type lighting using violet-excitation light-emitting diodes (LED) with an action spectrum centered at approximately 405 nm was developed. Although violet-excitation LEDs can reduce melatonin suppression compared with blue-excitation LEDs, no studies have compared the effects of violet-excitation LEDs with those of blue-excitation LEDs on melatonin suppression. This study was designed to compare the effects of violet-excitation LEDs with those of blue-excitation LEDs on melatonin suppression, psychomotor vigilance, and sleepiness...

STUDY OBJECTIVES: Airway inflammation in patients with obstructive sleep apnea (OSA) has been described and can be assessed by measuring the biomarker fractional exhaled nitric oxide (FeNO). In this pilot-study; we investigated FeNO measurements in identification of OSA among persons with snoring. METHODS: In this study we aimed to investigate: 1) if FeNO could be used in screening for OSA; 2) if daytime sleepiness correlated to FeNO levels; and 3) whether asthma affected FeNO levels...

STUDY OBJECTIVES: Drug-induced sleep endoscopy with positive airway pressure (DISE-PAP) evaluates the collapsibility of the upper airway. It is currently unknown if body position affects this assessment. We sought to determine whether the collapsibility of the airway may change with head of bed elevation. METHODS: A prospective, consecutive cohort study was performed by two sleep surgeons at a tertiary care center. Inclusion criteria included adults 18 years of age and older with obstructive sleep apnea who were intolerant to continuous positive airway pressure therapy...

STUDY OBJECTIVES: Prior studies have demonstrated the efficacy of lingual tonsillectomy (LT) in treating pediatric obstructive sleep apnea (OSA). The goal of this study is to describe the postoperative outcomes following LT as a part of drug-induced sleep endoscopy (DISE)-directed multilevel sleep surgery. METHODS: A retrospective review was performed for pediatric patients with OSA who underwent LT as a part of DISE-directed sleep surgery. Data collected included age, sex assigned at birth, body mass index (BMI) z-score, polysomnography results, past medical and surgical history, and postoperative outcomes...

No abstract text is available yet for this article.

STUDY OBJECTIVES: To evaluate the respiratory safety of lemborexant among adult and elderly subjects with moderate-to-severe obstructive sleep apnea (OSA). METHODS: E2006-A001-113 (Study 113; NCT04647383) was a double-blind, 2-period crossover, placebo-controlled study in adults (ages ≥45 to ≤90 years, n=33) with moderate (Apnea-Hypopnea Index [AHI] score ≥15 to <30/h, n=13) or severe (AHI ≥30/h, n=20) OSA. Subjects were randomized to lemborexant 10 mg (LEM10) or placebo (PBO) for 2 treatment periods of 8 nights with a ≥14-day washout period...

No abstract text is available yet for this article.

STUDY OBJECTIVES: Obstructive sleep apnea (OSA) and low bone mineral density (BMD) are two prevalent conditions with a significant negative impact on patients' well-being and quality of life. Recent research consistently showed low BMD at different bone sites in male patients with OSA. Although the efficacy of continuous positive airway pressure (CPAP) treatment for OSA has been widely demonstrated, the evidence for understanding its impact on BMD and other bone-related outcomes is insufficient...

This study evaluated the accuracy of the algorithmic SpO2 nadir detection of WatchPAT compared to visual inspection in a real-world setting. SpO2 tracings for 209 consecutive adult WatchPAT recordings were reviewed for SpO2 artifact, with erroneous SpO2 data removed manually. Error rate for SpO2 minima were determined across all studies, and relationships between correct and erroneous studies examined. The overall error rate for SpO2 nadir was 22.5%. Erroneous studies had overall less time spent at SpO2≤88%, higher true SpO2 nadir, lower mean body mass index, and greater artifact time, however, these variables were not associated with the magnitude of discrepancy between manual and algorithmically derived SpO2 minima...

STUDY OBJECTIVES: This meta-analysis aimed to investigate the feasibility and effectiveness of continuous positive airway pressure (CPAP) treatment in stroke patients with sleep apnea. METHODS: PubMed, EMBASE, and the Cochrane Library were searched from inception until July 28, 2022, for randomized controlled trials comparing the use of CPAP and usual treatment in patients with stroke or transient ischemic attack and sleep apnea. The primary outcome measures were the feasibility of CPAP therapy, neurological function, and functional status...

No abstract text is available yet for this article.

No abstract text is available yet for this article.

The modern practice of sleep medicine in China was introduced in the 1980s and has undergone significant development over the past few decades. The field has witnessed an increase in sleep laboratories, the publication of guidelines for the diagnosis and treatment of sleep disorders, and the establishment of several sleep medicine associations. Despite these achievements, there is still much to be done in this field. By utilizing original national survey data, this study comprehensively discusses the current practice of sleep medicine in China, including sleep medicine training, diagnostic capacity, multidisciplinary care, clinical competence and standardization, sleep telemedicine, barriers to the practice of sleep medicine, and costs of sleep medicine...

STUDY OBJECTIVES: Polycystic ovary syndrome (PCOS) confers a high risk of obstructive sleep apnea (OSA). Here we investigated the effect of OSA on first in vitro fertilization (IVF) cycle metrics and outcomes in PCOS patients. METHODS: This was a prospective cohort study of PCOS patients undergoing first IVF at a single tertiary center between October 1, 2021 and September 30, 2022. Patients were screened for OSA before IVF and grouped accordingly. Clinical and IVF cycle data were compared between groups...

STUDY OBJECTIVES: Sleep disturbances are common in people with Alzheimer's disease (AD), with a reduction in slow-wave activity (SWA) being the most striking underlying change. Acoustic stimulation has emerged as a promising approach to enhance SWA in healthy adults and people with amnestic mild cognitive impairment. In this phase 1 study we investigated, for the first time, the feasibility of acoustic stimulation in AD and piloted the effect on slow-wave sleep (SWS). METHODS: Eleven adults with mild to moderate AD first wore the DREEM2 headband (DH) for two nights to establish a baseline registration...

Hallucinations are false sensory perceptions that occur in the absence of an external stimulus. Three cases of hallucinations related to OSAHS are reported, two of which improved with the initiation of CPAP therapy. So far there are no published reports in the literature that account for this relationship in the absence of primary or structural mental pathology. All 3 reported patients had visual hallucinations that were uncomfortable and frightening. Polysomnography showed moderate to severe OSAHS with severe oxygen desaturation...

STUDY OBJECTIVES: Upper airway stimulation (UAS) is a hybrid surgical-medical device used to treat moderate-to-severe obstructive sleep apnea (OSA). Comorbid insomnia and obstructive sleep apnea (COMISA) is present in ~50% of these patients. Our aim was to study UAS outcomes and adherence in COMISA patients. METHODS: Retrospective review of 379 OSA patients who underwent UAS implantation at a single institution between 2014-2021. Demographics, OSA severity metrics, and insomnia data were collected...

STUDY OBJECTIVES: Postoperative respiratory complications (PORC) can occur following supraglottoplasty (SGP) for obstructive sleep apnea (OSA). However, there are very limited data on risk factors associated with these complications. This study aims to evaluate the occurrence of PORC in children undergoing SGP and to assess clinical factors and polysomnographic (PSG) parameters predicting these complications. METHODS: A retrospective study was performed in children with laryngomalacia who underwent SGP with preoperative PSG...

STUDY OBJECTIVES: The aim of this study was to evaluate gender-related differences in symptoms of sleep disorders, sleep-related impairment, psychiatric symptoms, traumatic brain injury (TBI), and polysomnographic (PSG) variables in treatment-seeking military personnel diagnosed with insomnia, obstructive sleep apnea (OSA), or comorbid insomnia and OSA (COMISA). METHODS: Participants were 372 military personnel (46.2% women, 53.8% men) with an average age of 37...