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Heart Failure Clinics

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https://read.qxmd.com/read/30449386/heart-failure-in-women-an-increasing-health-concern
#1
EDITORIAL
Gina Price Lundberg, Eduardo Bossone, Laxmi S Mehta
No abstract text is available yet for this article.
January 2019: Heart Failure Clinics
https://read.qxmd.com/read/30449385/advanced-therapies-for-advanced-heart-failure-in-women
#2
REVIEW
Marlena V Habal, Kelly Axsom, Maryjane Farr
Women with advanced heart failure (HF) are underrepresented in trials of short-term and durable mechanical circulatory support although they derive similar benefit. In acute HF, intensive medical and interventional therapies are effective but underutilized. The smaller, newer generation, left ventricular assist devices (LVADs) have increased the feasibility of durable support in women. Women frequently present late, with more comorbidities, emphasizing the need for timely referral. Compared with men, the stroke risk is higher in women with an LVAD...
January 2019: Heart Failure Clinics
https://read.qxmd.com/read/30449384/heart-failure-with-preserved-ejection-fraction-in-women
#3
REVIEW
Anjan Tibrewala, Clyde W Yancy
Heart failure with preserved ejection fraction (HFpEF) is an increasingly prevalent condition, particularly in women. Comorbidities, including older age, obesity, diabetes mellitus, hypertension, and hyperlipidemia, are risk factors and define phenotypic profiles of HFpEF in women. The condition has a relatively high burden of morbidity and mortality, with phenotypic profiles potentially characterizing risk of hospitalization and mortality. Based on limited data, nonpharmacologic and pharmacologic treatments may provide benefit; however, compelling evidence-based, disease-modifying treatments are needed...
January 2019: Heart Failure Clinics
https://read.qxmd.com/read/30449383/heart-failure-in-women-with-congenital-heart-disease
#4
REVIEW
Elisa A Bradley, Anita Saraf, Wendy Book
Heart failure remains the most common cause of morbidity and mortality in adults with congenital heart disease (CHD). Although gender-specific outcomes are not robust, it seems that women with CHD may be more affected by late heart failure (HF) than men. A specialized and experienced adult CHD team is required to care for these women as they age, including assessment for reversible causes of HF and in the management of pregnancy, labor, and delivery.
January 2019: Heart Failure Clinics
https://read.qxmd.com/read/30449382/valvular-heart-disease-and-heart-failure-in-women
#5
REVIEW
Daniela R Crousillat, Malissa J Wood
Valvular heart disease and heart failure remain important causes of cardiovascular disease among women in the United States. Mitral regurgitation, aortic stenosis, and tricuspid regurgitation are the most common valvular lesions among men and women. This review focuses on gender differences in the epidemiology, treatment, and outcomes of mitral regurgitation, aortic stenosis, and tricuspid regurgitation. The authors also review the unique management of valvular heart disease in pregnancy.
January 2019: Heart Failure Clinics
https://read.qxmd.com/read/30449381/breast-cancer-and-heart-failure
#6
REVIEW
Zakaria Almuwaqqat, Jane L Meisel, Ana Barac, Susmita Parashar
Heart failure and breast cancer have shared risks and morbidities. Multimodality therapies for breast cancer, including conventional chemotherapy, targeted therapeutics, radiation therapy, and hormonal agents, may make patients more susceptible to asymptomatic left ventricular dysfunction and clinical heart failure during and after treatment. New or preexisting left ventricular dysfunction may lead to interruptions in cancer treatment and limit options of breast cancer systemic therapy, leading to adverse outcomes...
January 2019: Heart Failure Clinics
https://read.qxmd.com/read/30449380/atrial-fibrillation-and-heart-failure-in-women
#7
REVIEW
Nidhi Madan, Dipti Itchhaporia, Christine M Albert, Neelum T Aggarwal, Annabelle Santos Volgman
Atrial fibrillation often occurs as a cause or consequence of heart failure. Clinical outcomes are worse when atrial fibrillation and heart failure coexist. There are important sex-related differences in the incidence, prevalence, pathophysiology, treatment, and outcomes of these patients. Women with heart failure are at greater risk of developing atrial fibrillation than men, and more women with atrial fibrillation develop heart failure. More women die of atrial fibrillation-related strokes. Despite significant morbidity and mortality, current treatments for women are inadequate...
January 2019: Heart Failure Clinics
https://read.qxmd.com/read/30449379/stress-induced-cardiomyopathy
#8
REVIEW
Lili Zhang, Ileana L Piña
Stress-induced cardiomyopathy is characterized by reversible myocardial injury with distinctive regional wall motion abnormalities of the left ventricle, usually precipitated by an emotional or physical stressor. This condition has a strong predilection for older women and has a trend of increasing incidence. The diagnosis can be made based on symptoms, biomarkers, electrocardiogram, coronary angiogram, and noninvasive imaging. It is frequently complicated by acute heart failure, cardiogenic shock, arrhythmias, left ventricular outflow tract obstruction, and ventricular thrombi...
January 2019: Heart Failure Clinics
https://read.qxmd.com/read/30449378/peripartum-cardiomyopathy-progress-in-understanding-the-etiology-management-and-prognosis
#9
REVIEW
Kathryn J Lindley, Amanda K Verma, Lori A Blauwet
Occurring in approximately 1 in 1000 live births in the United States, peripartum cardiomyopathy (PPCM) is characterized by left ventricular ejection fraction reduced to less than 45% near the end of pregnancy or within the first 5 months after delivery. Although the cause of PPCM remains unclear, increasing evidence supports a complex interaction of genetic and environmental factors contributing to angiogenic imbalance, which may lead to myocardial dysfunction in a susceptible woman. This article reviews the progress that has been made regarding understanding of the cause, management, and natural history of PPCM...
January 2019: Heart Failure Clinics
https://read.qxmd.com/read/30449377/heart-failure-with-reduced-ejection-fraction-in-women-epidemiology-outcomes-and-treatment
#10
REVIEW
Gina Mentzer, Eileen M Hsich
There are millions of people affected by heart failure with reduced ejection fraction (HFrEF) as diagnosed with ejection fraction 40% or less by imaging. Established therapies have been proven through clinical trials on lifestyle interventions, medications, and devices for HFrEF to improve quality of life, heart function, and survival. Although there are more men than women suffering with HFrEF, there are no prospectively proven, sex-specific guideline therapies because women have been underrepresented in clinical trials...
January 2019: Heart Failure Clinics
https://read.qxmd.com/read/30449376/pulmonary-hypertension-in-women
#11
REVIEW
Veronica Franco, John J Ryan, Vallerie V McLaughlin
Prevalence of pulmonary arterial hypertension (PAH) is higher in women, and the mechanism remains unclear. Prognosis is overall better for female compared with male patients with PAH. Pregnancy is associated with significant risk, mortality, and morbidity in patients with PAH; consensus guidelines recommend against pregnancy and counsel about early termination in these patients. Recent advances in treatment showed improvement in prognosis in small case reports of pregnant patients with PAH, particularly with the early use of parental prostacyclin...
January 2019: Heart Failure Clinics
https://read.qxmd.com/read/30449375/heart-transplantation-in-women
#12
REVIEW
Ayesha Hasan, Michelle M Kittleson
Over the past 5 decades, heart transplantation has become an established therapy with greater quality of life and survival than expected from end-stage heart failure. Nonetheless, challenges still exist, especially for women undergoing heart transplantation. Women have greater post-transplant survival than their male counterparts but worse quality of life. Pregnancy may occur, especially because more women are reaching child-bearing age after transplantation. Successful outcomes have been reported but require a systematic multidisciplinary approach...
January 2019: Heart Failure Clinics
https://read.qxmd.com/read/30449374/implantable-cardioverter-defibrillators-and-cardiac-resynchronization-therapy-in-women
#13
REVIEW
Maya T Ignaszewski, Stacie L Daugherty, Andrea M Russo
Implantable cardioverter-defibrillator and cardiac resynchronization therapy devices have been prescribed for patients with heart failure for several decades. Factors leading to increased usage include significant enhancements in technology and availability of multiple randomized clinical trials demonstrating their benefit with improved implementation of evidence-based guidelines. Despite these advances, gaps still exist in the utilization and referral of these devices, particularly among women. This article reviews the literature on these devices with a focus on gender differences and proposes reasons for why they exist...
January 2019: Heart Failure Clinics
https://read.qxmd.com/read/30449373/sex-specific-differences-in-risk-factors-for-development-of-heart-failure-in-women
#14
REVIEW
Gina Lundberg, Mary Norine Walsh, Laxmi S Mehta
Sex specific differences exist in the impact of risk factors for the development of heart failure (HF). Addressing these differences can have an impact on prevention of HF. This article reviews sex-specific risk factors associated with development of HF. These risk factors include current smoking, diabetes, hypertension, and myocardial infarction. Other risks for HF are toxins, inflammation, and other chronic conditions, such as sleep breathing disorders, anemia, obesity, and renal insufficiency. Some of these risks factors present risk reduction opportunities that may improve outcomes...
January 2019: Heart Failure Clinics
https://read.qxmd.com/read/30266372/preface
#15
EDITORIAL
Ragavendra R Baliga, Umesh C Samal, Eduardo Bossone
No abstract text is available yet for this article.
October 2018: Heart Failure Clinics
https://read.qxmd.com/read/30266371/management-of-sleep-apnea-in-heart-failure
#16
REVIEW
Ali Vazir, Varun Sundaram
Sleep-disordered breathing (SDB) is highly prevalent in heart failure (HF). The presence of SDB in patients with HF appears to be associated with increased risk of cardiovascular morbidity and mortality. In this article, we describe the types, pathophysiology, and consequences of SDB and discuss ways in which SDB can be diagnosed. We also lay emphasis on the recent randomized controlled trials that have had a major impact on how SDB is managed and highlight the complex relationship between SDB and outcomes.
October 2018: Heart Failure Clinics
https://read.qxmd.com/read/30266370/interventional-heart-failure-and-hemodynamic-monitoring
#17
REVIEW
Umair Ahmad, Scott M Lilly
Convergence of the fields of heart failure (HF) and interventional cardiology has led to the formation of a discipline referred to as interventional HF. Although the term may be applied to essentially any invasive procedure performed in patients with HF (eg, coronary angiography, percutaneous coronary intervention, invasive assessment of hemodynamics), it is more commonly reserved for the application of invasive diagnostic or therapeutic procedures to improve the clinical decision-making, functional status, and outcomes of HF patients...
October 2018: Heart Failure Clinics
https://read.qxmd.com/read/30266369/palliative-therapy-in-heart-failure
#18
REVIEW
Christopher M Hritz
Cardiac palliative care is a multidisciplinary approach provided alongside standard heart failure management to improve a patient's quality of life. In this article the authors review the role of palliative care in heart failure management, including recent studies exploring the benefits of palliative care consultation in the inpatient and outpatient setting. They also discuss approaches to goals-of-care discussions and challenges providing end-of-life care in this patient population.
October 2018: Heart Failure Clinics
https://read.qxmd.com/read/30266368/current-status-of-inotropes-in-heart-failure
#19
REVIEW
Mahazarin Ginwalla, David S Tofovic
Inotropes are medications that improve the contractility of the heart and are used in patients with low cardiac output or evidence of end-organ dysfunction. Since their initial discovery, inotropes have held promise in alleviating symptoms and potentially increasing longevity in such patients. Decades of intensive study have further elucidated the benefits and risks of using inotropes. In this article, the authors discuss the history of inotropes, their indications, mechanism of action, and current guidelines pertaining to their use in heart failure...
October 2018: Heart Failure Clinics
https://read.qxmd.com/read/30266367/mitral-valve-surgery-for-congestive-heart-failure
#20
REVIEW
Juan A Crestanello
Mitral valve diseases are common causes of congestive heart failure. Chronic primary and secondary (functional) mitral valve regurgitation are the most common reasons. Valve repair for primary mitral regurgitation cures mitral valve disease, whereas in functional regurgitation, mitral valve repair is associated with high failure rates secondary to persistent/progressive ventricular dysfunction and remodeling. Most patients are managed with strict adherence to the valve guidelines. Mitral valve replacement has an increased role in management of functional mitral regurgitation...
October 2018: Heart Failure Clinics
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