Yongjie Zhang, Yangli Wang, Xin Liao, Tong Liu, Fengyuan Yang, Kaiqiang Yang, Zhuohua Zhou, Yinxu Fu, Ting Fu, Aliaksei Sysa, Xiandan Chen, Yao Shen, Jianxin Lyu, Qiongya Zhao
Metabolic-associated fatty liver disease (MAFLD) is related to metabolic dysfunction and is characterized by excess fat storage in the liver. Several studies have indicated that glutamine could be closely associated with lipid metabolism disturbances because of its important role in intermediary metabolism. However, the effect of glutamine supplementation on MAFLD progression remains unclear. Here, we used a high-fat diet (HFD)-induced MAFLD C57BL/6 mouse model, and glutamine was supplied in the drinking water at different time points for MAFLD prevention and reversal studies...
March 8, 2024: Nutrition & Metabolism