Sourav Mohanto, Md Faiyazuddin, Amol Dilip Gholap, Darshan Jogi, Adrija Bhunia, Kannan Subbaram, Mohammed Gulzar Ahmed, Sagnik Nag, Mohammad Shabib Akhtar, D Katterine Bonilla-Aldana, Sanjit Sah, Sumira Malik, Zahraa Haleem Al-qaimN, Joshuan J Barboza, Ranjit Sah
Monkeypox (Mpox) is a transmissible infection induced by the Monkeypox virus (a double-stranded DNA virus), recognised under the family orthopoxvirus genus. Monkeypox, like endemic diseases, is a substantial concern worldwide; thus, comprehending the pathogenesis and mutagenesis of amino acids is indispensable to combat the infection. According to the World Health Organization's report, about 87 thousand cases with 112 mortalities have been reported from 110 countries worldwide. The conventional orthopoxvirus vaccines developed on live attenuated viruses exempted any clinical validation from combating monkeypox due to inadequate immunogenicity, toxicity, instability, and multiple doses...
August 24, 2023: Travel Medicine and Infectious Disease