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Canadian Journal of Infectious Diseases & Medical Microbiology

https://read.qxmd.com/read/38984269/modeling-for-prediction-of-mortality-based-on-past-medical-history-in-hospitalized-covid-19-patients-a-secondary-analysis
#1
JOURNAL ARTICLE
Seyyed Amir Yasin Ahmadi, Yeganeh Karimi, Arash Abdollahi, Ali Kabir
INTRODUCTION: Although COVID-19 is not currently a public health emergency, it will affect susceptible individuals in the post-COVID-19 era. Hence, the present study aimed to develop a model for Iranian patients to identify at-risk groups based on past medical history (PMHx) and some other factors affecting the death of patients hospitalized with COVID-19. METHODS: A secondary study was conducted with the existing data of hospitalized COVID-19 adult patients in the hospitals covered by Iran University of Medical Sciences...
2024: Canadian Journal of Infectious Diseases & Medical Microbiology
https://read.qxmd.com/read/38938549/immunization-against-medically-important-human-coronaviruses-of-public-health-concern
#2
REVIEW
Nabil A Nimer, Seema N Nimer
SARS-CoV-2 is a virus that affects the human immune system. It was observed to be on the rise since the beginning of 2020 and turned into a life-threatening pandemic. Scientists have tried to develop a possible preventive and therapeutic drug against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and other related coronaviruses by assessing COVID-19-recovered persons' immunity. This study aims to review immunization against SARS-CoV-2, along with exploring the interventions that have been developed for the prevention of SARS-CoV-2...
2024: Canadian Journal of Infectious Diseases & Medical Microbiology
https://read.qxmd.com/read/38938548/interaction-of-glycemic-control-and-statin-use-on-diabetes-tuberculosis-treatment-outcome-a-nested-case-control-study
#3
JOURNAL ARTICLE
Xiangrui Meng, Huiqiu Zheng, Jian Du, Xuemei Wang, Yanling Wang, Jing Hu, Jing Zhao, Qianqian Du, Yulong Gao
This study aims to explore the interaction of glycemic control and statin use on the treatment outcomes of pulmonary tuberculosis-diabetes comorbidity (PTB-DM) patients. A nested case-control study was conducted in a tuberculosis patients' cohort. We defined cases as patients who experienced unfavorable outcomes. Glycemic control was estimated at the baseline. Statin use was obtained from medical records. The multivariate logistic regression models were developed, and the interaction table invented by Andersson was adopted to analyze the interaction of glycemic control and statin use on treatment outcomes...
2024: Canadian Journal of Infectious Diseases & Medical Microbiology
https://read.qxmd.com/read/38826677/prevalence-and-residual-risk-of-hiv-in-volunteer-blood-donors-of-zhejiang-province-china-from-2018-to-2022
#4
JOURNAL ARTICLE
Hong Zhu, Wei Ding, Wenjuan Han, Xiaofan Zheng, Yiqing Hu, Jie Dong, Yaling Wu, Danxiao Wu, Jinhui Liu, Faming Zhu
BACKGROUND: Blood safety levels have been significantly improved since the implementation of nucleic acid amplification technology (NAT) testing for blood donors. However, there remains a residual risk of transfusion transmission infections. This study aimed to evaluate the prevalence of HIV and its residual risk transmission among volunteer blood donors of Zhejiang Province, China, for five years after NAT implementation. MATERIALS AND METHODS: All specimens and information were collected from voluntary unpaid donors at all blood services in Zhejiang Province, China, from January 2018 to December 2022...
2024: Canadian Journal of Infectious Diseases & Medical Microbiology
https://read.qxmd.com/read/38826676/outer-membrane-vesicles-derived-from-adherent-invasive-escherichia-coli-induce-inflammatory-response-and-alter-the-gene-expression-of-junction-associated-proteins-in-human-intestinal-epithelial-cells
#5
JOURNAL ARTICLE
Bahareh Nadalian, Banafsheh Nadalian, Mohammad Reza Zali, Abbas Yadegar
Adherent-invasive Escherichia coli (AIEC) pathobionts, which are characterized by their ability to adhere to and invade intestinal epithelial cells, are associated with the etiopathogenesis of inflammatory bowel diseases (IBDs). Outer membrane vesicles (OMVs) released by AIEC strains can facilitate the interaction of these bacteria with host cells through delivering bacterial effectors. The aim of this study was to determine the ability of OMVs derived from AIEC strain LF82 to induce the host immune response, leading to production of proinflammatory cytokines and also altering the gene expression of junction-associated proteins in the human epithelial colorectal adenocarcinoma Caco-2 cell line...
2024: Canadian Journal of Infectious Diseases & Medical Microbiology
https://read.qxmd.com/read/38808260/evaluation-of-the-efficacy-and-safety-of-intravenous-immunoglobulin-ivig-in-moderate-to-severe-hospitalized-covid-19-patients-a-randomized-open-label-parallel-group-study
#6
JOURNAL ARTICLE
Sachin Gautam, Govind Mawari, Mradul Kumar Daga, Naresh Kumar, Harpreet Singh, Sandeep Garg, Suresh Kumar, Monika Gajendrakumar, Mahak Golani, Ishan Rohatgi, Sayan Sarkar, Shubham Kaushik, Manish Kumar Jha, Sweety Mehra
PURPOSE: Since February 2020, the world has been overwhelmed by the SARS-CoV-2 outbreak, and several patients suffered interstitial pneumonia and respiratory failure requiring mechanical ventilation, threatening the capability of healthcare systems to handle this amount of critical cases. Intravenous immunoglobulins (IVIG) possess potential immunomodulatory properties beneficial for COVID-19 patients, yet evidence supporting IVIG as adjunctive therapy remains sparse. This study evaluated the outcomes of adjunctive IVIG with the standard of care (SoC) in moderate-to-severe COVID-19 patients...
2024: Canadian Journal of Infectious Diseases & Medical Microbiology
https://read.qxmd.com/read/38779616/covid-19-vaccines-in-the-pediatric-population-a-focus-on-cardiac-patients
#7
REVIEW
Ghena Lababidi, Hossam Lababidi, Fadi Bitar, Mariam Arabi
Due to the deleterious global impact of the COVID-19 pandemic, tremendous effort has been invested in the development of vaccines against the virus. Vaccine candidates are first tested in adult populations, a number of which have been approved for EUL by the WHO, and are in use across the USA and MENA region. The question remains whether these (or other) vaccines should be recommended to a neonatal, pediatric, and/or adolescent cohort. Incidence and severity of COVID-19 infection are low in pediatric, neonatal, and adolescent patients...
2024: Canadian Journal of Infectious Diseases & Medical Microbiology
https://read.qxmd.com/read/38698837/antimicrobial-susceptibility-profiles-of-klebsiella-pneumoniae-strains-collected-from-clinical-samples-in-a-hospital-in-southern-italy
#8
JOURNAL ARTICLE
Biagio Santella, Mariarosaria Boccella, Veronica Folliero, Domenico Iervolino, Pasquale Pagliano, Luigi Fortino, Bianca Serio, Emilia Anna Vozzella, Luigi Schiavo, Massimiliano Galdiero, Mario Capunzo, Giovanni Boccia, Gianluigi Franci
Infections caused by antibiotic-resistant bacteria represent a serious threat to global public health. Recently, due to its increased resistance to carbapenems and β -lactams, Klebsiella pneumoniae has become one of the main causes of septicemia, pneumonia, and urinary tract infections. It is crucial to take immediate action and implement effective measures to prevent further spread of this issue. This study aims to report the prevalence and antibiotic resistance rates of K. pneumoniae strains isolated from clinical specimens from 2015 to 2020 at the University Hospital of Salerno, Italy...
2024: Canadian Journal of Infectious Diseases & Medical Microbiology
https://read.qxmd.com/read/38660495/evaluating-antibiotic-treatment-guideline-adherence-to-ongoing-antibiotic-stewardship-in-a-tertiary-care-setting-a-retrospective-observational-study
#9
JOURNAL ARTICLE
Suman Pant, Andrew Corwin, Prabhat Adhikari, Subhash Prasad Acharya, Upasana Acharya, Sashi Silwal, Pratima Dawadi, Anil Poudyal, Vibhu Paudyal, Adisak Bhumiratana
Antimicrobial resistance (AMR) is widely regarded as an increasing threat to global public health. Antibiotic treatment guidelines have been increasingly recognized as an effective tool to guide appropriate prescriptions and help curtail antibiotic resistance. The present study aimed to assess physician's adherence to hospital antibiotic treatment guideline recommendations in Nepal and determine predictive variables with a significant association. This was a retrospective, monocentric observational review to investigate the adherence to endorsed guidelines using the medical records of adults admitted to the hospital with a diagnosis of urinary tract infection (UTI), pneumonia, or skin and soft tissue infection (SSTI) from January 2018 to December 2019...
2024: Canadian Journal of Infectious Diseases & Medical Microbiology
https://read.qxmd.com/read/38660494/a-unique-combination-of-mn-2-and-aluminum-adjuvant-acted-the-synergistic-effect
#10
JOURNAL ARTICLE
Yuwei Cen, Shujie Chen, Shuyu Wei, Shuangshuang Wu, Mingyang Tao, Youxi Fu, Yuncheng Wang, Jing Chen, Yixuan Ma, Hongyan Liu, Baifen Song, Jinzhu Ma, Beiyan Wang, Yudong Cui
INTRODUCTION: The development of combinatorial adjuvants is a promising strategy to boost vaccination efficiency. Accumulating evidence indicates that manganese exerts strong immunocompetence and will become an enormous potential adjuvant. Here, we described a novel combination of Mn2+ plus aluminum hydroxide (AH) adjuvant that significantly exhibited the synergistic immune effect. Methodology . Initially, IsdB3 proteins as the immune-dominant fragment of IsdB proteins derived from Staphylococcus aureus ( S...
2024: Canadian Journal of Infectious Diseases & Medical Microbiology
https://read.qxmd.com/read/38623587/the-abundance-of-plasmid-mediated-quinolone-resistance-genes-in-enterobacter-cloacae-strains-isolated-from-clinical-specimens-in-kermanshah-iran
#11
JOURNAL ARTICLE
Mandana Afsharian, Somayeh Asadi, Camellia Danesh, Reza Sedighi, Kohsar Karimi, Nooshin Miladi, Ronak Miladi, Mohsen Azizi, Nahid Madadi-Goli, Kamal Ahmadi, Mohammad Hossein Zamanian
BACKGROUND: Enterobacter cloacae ( E. cloacae ) is one of the most common Enterobacteriaceae causing nosocomial infections. Plasmid-mediated quinolone resistance (PMQR) determinants have been considered recently. This study evaluated the abundance of PMQR genes in strains of E. cloacae obtained from clinical samples in Kermanshah, Iran. METHODS: In this descriptive cross-sectional study, after collecting 113 isolates of E. cloacae , their identity was confirmed using specific biochemical tests...
2024: Canadian Journal of Infectious Diseases & Medical Microbiology
https://read.qxmd.com/read/38532829/assessment-of-hand-washing-knowledge-and-practice-among-nursing-undergraduates-in-saudi-arabia
#12
JOURNAL ARTICLE
Wajid Syed, Mahmood Basil A Al-Rawi
PURPOSE: The present study investigated the knowledge and practice of hand hygiene among entry-level nursing students at King Saud University in Riyadh, Saudi Arabia. Participants and Methods : A cross-sectional, institutional-based study was conducted among Saudi nursing students over a period of four months at the King Saud University College of Nursing, using a structured, self-administered questionnaire that assessed demographics, knowledge, and the practice of hand washing. RESULTS: A response rate of 95% was obtained...
2024: Canadian Journal of Infectious Diseases & Medical Microbiology
https://read.qxmd.com/read/38532828/clinical-characteristics-and-microorganisms-isolated-in-community-acquired-pneumonia-in-the-covid-19-period
#13
JOURNAL ARTICLE
Meritxell Gavalda, Maria Isabel Fullana, Adrià Ferre, Rebecca Rowena Peña, Julen Armendariz, Orla Torrallardona, Aina Magraner, Alejandro Lorenzo, Carles García, Gemma Mut, Lluís Planas, Carla Iglesias, Pablo Fraile-Ribot, Maria Dolores Macia Romero, Melchor Riera, Mercedes García-Gasalla
INTRODUCTION: Community-acquired pneumonia is a leading cause of mortality and hospital admissions. The aetiology remains unknown in 30-65% of the cases. Molecular tests are available for multiple pathogen detection and are under research to improve the causal diagnosis. METHODS: We carried out a prospective study to describe the clinical characteristics and aetiology of community-acquired pneumonia during the COVID-19 pandemic and to assess the diagnostic effectivity of the microbiological tests, including a molecular test of respiratory pathogens (FilmArray™ bioMérieux)...
2024: Canadian Journal of Infectious Diseases & Medical Microbiology
https://read.qxmd.com/read/38487175/-leishmania-major-infection-in-synanthropic-rodents-evidence-for-the-urbanization-of-zoonotic-cutaneous-leishmaniasis-zcl-in-southern-iran
#14
JOURNAL ARTICLE
Saeed Shahabi, Kourosh Azizi, Qasem Asgari, Bahador Sarkari
Cutaneous leishmaniasis is of particular importance in southern Iran. This study aimed to investigate the infection of rodents with Leishmania major in an urban area of Fars Province, located in southern Iran. Rodents were trapped and samples from the liver, spleen, and skin were collected. Impression smears were prepared from these tissues and any skin lesions and were examined microscopically. In addition, a portion of the samples were preserved for subsequent DNA extraction. A total of 41 rodents belonging to three species were caught from 10 trapping stations in gardens or houses within the area...
2024: Canadian Journal of Infectious Diseases & Medical Microbiology
https://read.qxmd.com/read/38476862/relationship-between-antibiotic-consumption-and-resistance-a-systematic-review
#15
REVIEW
Asrat Agalu Abejew, Gizachew Yismaw Wubetu, Teferi Gedif Fenta
BACKGROUND: Unreserved use of antibiotics exerted selective pressure on susceptible bacteria, resulting in the survival of resistant strains. Despite this, the relationship between antibiotic resistance (ABR) and antibiotic consumption (ABC) is rarely studied. This systematic review aims to review the relationship between ABC and ABR from 2016 to 2022. METHODS: Articles published over 7 years (2016-2022) were searched from December 23 to 31, 2022. The search strategy was developed by using keywords for ABC and ABR...
2024: Canadian Journal of Infectious Diseases & Medical Microbiology
https://read.qxmd.com/read/38469104/fulminant-myocarditis-with-sars-cov-2-infection-a-narrative-review-from-the-case-studies
#16
REVIEW
Ryohei Ono, Togo Iwahana, Kaoruko Aoki, Hirotoshi Kato, Sho Okada, Yoshio Kobayashi
One of the severe complications of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is myocarditis. However, the characteristics of fulminant myocarditis with SARS-CoV-2 infection are still unclear. We systematically reviewed the previously reported cases of fulminant myocarditis associated with SARS-CoV-2 infection from January 2020 to December 2022, identifying 108 cases. Of those, 67 were male and 41 female. The average age was 34.8 years; 30 patients (27.8%) were ≤20 years old, whereas 10 (9...
2024: Canadian Journal of Infectious Diseases & Medical Microbiology
https://read.qxmd.com/read/38440403/isolation-and-identification-of-effective-probiotics-on-drug-resistant-acinetobacter-baumannii-strains-and-their-biofilms
#17
JOURNAL ARTICLE
Zahra Abbasi, Seyed Mahdi Ghasemi, Yasaman Ahmadi, Dariush Shokri
INTRODUCTION: This study aimed to identify, assess, and isolate strong lactobacilli demonstrating broad antibacterial and anti-biofilm activity against drug-resistant strains of Acinetobacter baumannii . Additionally, the mechanism of inhibition of these organisms was to be determined. METHODS: Over a 6-month period (from December 2021 to June 2022), 53 clinical A. baumannii strains were collected from clinical samples. Twenty probiotic strains were isolated from local dairy products...
2024: Canadian Journal of Infectious Diseases & Medical Microbiology
https://read.qxmd.com/read/38425657/epidemiology-and-performances-of-typhidot-immunoassay-and-widal-slide-agglutination-in-the-diagnosis-of-typhoid-fever-in-febrile-patients-in-bafoussam-city-cameroon-a-cross-sectional-comparative-study
#18
JOURNAL ARTICLE
Aurelie Dahlia Yemeli Piankeu, Siméon Pierre Chegaing Fodouop, Michel Noubom, Emmanuel Boris Gomseu Djoumsie, Georges Ful Kuh, Donatien Gatsing
BACKGROUND: Enteric fever is a great public health problem associated with significant illness and death in many endemic countries, and its clinical diagnosis is still daunting. The aim of this study was to determine the prevalence and risk factors of S. Typhi among febrile patients in Bafoussam and to evaluate the diagnostic performances of Widal and Typhidot tests. METHODS: This was a cross-sectional study among 336 participants visiting three hospitals in Bafoussam from August 1, 2021, to November 31, 2021...
2024: Canadian Journal of Infectious Diseases & Medical Microbiology
https://read.qxmd.com/read/38419669/psychological-status-of-medical-staff-in-obstetrics-and-gynecology-hospitals-during-the-omicron-pandemic-outbreak-in-china
#19
JOURNAL ARTICLE
Shuting Bao, Bangwu Chen, Ying Hu, Chee Shin Lee, Qi Wu, Menglin Zhou, Mengkai Du, Shuqi Zhu, Biao Xie, Jiuqiong Hu, Zhaoxia Liang
BACKGROUND: Medical staff in China faced great challenges and psychological and physiological changes of varying degrees during the omicron epidemic outbreak. It is important to recognize the potential impact of these challenges on the mental health of medical staff and to provide appropriate resources and support to mitigate their effects. METHODS: A total of 354 medical staff in two obstetrics and gynecology hospitals of different grades were included in this survey using convenience sampling...
2024: Canadian Journal of Infectious Diseases & Medical Microbiology
https://read.qxmd.com/read/38384430/epidemiology-of-brucellosis-in-small-ruminants-of-rural-and-peri-urban-areas-of-multan-pakistan
#20
JOURNAL ARTICLE
Mian Muhammad Awais, Bakhtawar Khadim, Masood Akhtar, Muhammad Irfan Anwar, Gohar Khadim, Abdul Sammad Ali Khan Shirwany, Halil Selcuk Biricik, Abdul Razzaq, Muhammad Sibtain Bhatti
Brucellosis is a widespread zoonotic disease of veterinary and public health importance with considerably higher prevalence in developing/underdeveloped countries. This study reports the prevalence and risk determinants of brucellosis in small ruminants of peri-urban and rural areas of district Multan, Southern Punjab, Pakistan. For this purpose, sera samples ( n  = 392) of small ruminants were collected and subjected to preliminary screening using commercially available RBPT reagents followed by serodetection of brucellosis using multispecies i-ELISA kit (ID...
2024: Canadian Journal of Infectious Diseases & Medical Microbiology
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