journal
https://read.qxmd.com/read/23036262/mood-and-the-menstrual-cycle-a-review-of-prospective-data-studies
#21
REVIEW
Sarah Romans, Rose Clarkson, Gillian Einstein, Michele Petrovic, Donna Stewart
BACKGROUND: The human menstrual cycle (MC) has historically been the focus of myth and misinformation, leading to ideas that constrain women's activities. OBJECTIVES: We wished to examine one pervasive idea, that the MC is a cause of negative mood, by studying the scientific literature as a whole. We briefly reviewed the history of the idea of premenstrual syndrome and undertook a systematic review of quality studies. METHODS: We searched PubMed, PsycINFO, and article bibliographies for published studies using non-help-seeking samples with daily mood data collected prospectively for a minimum of 1 complete MC...
October 2012: Gender Medicine
https://read.qxmd.com/read/23000153/increased-medical-costs-in-elders-with-the-metabolic-syndrome-are-most-evident-with-hospitalization-of-men
#22
JOURNAL ARTICLE
Yu-Hung Chang, Rosalind Chia-Yu Chen, Meei-Shyuan Lee, Mark L Wahlqvist
BACKGROUND: Little is known about health care costs associated with the metabolic syndrome (MetS). OBJECTIVE: We assessed annualized health care costs and health outcomes for both genders in different health care settings among representative Taiwanese elders. METHODS: The Nutrition and Health Survey in Taiwan (1999-2000) provided 1378 individuals aged 65 years or older with known MetS status. Nutrition and Health Survey in Taiwan files were linked to National Health Insurance records (1999-2006)...
October 2012: Gender Medicine
https://read.qxmd.com/read/22981166/endogenous-androgen-deficiency-enhances-diet-induced-hypercholesterolemia-and-atherosclerosis-in-low-density-lipoprotein-receptor-deficient-mice
#23
JOURNAL ARTICLE
Nicholas W Hatch, Sarah J Srodulski, Huei-Wei Chan, Xuan Zhang, Lisa R Tannock, Victoria L King
BACKGROUND: Despite numerous clinical and animal studies, the role of sex steroid hormones on lipoprotein metabolism and atherosclerosis remain controversial. OBJECTIVE: We sought to determine the effects of endogenous estrogen and testosterone on lipoprotein levels and atherosclerosis using mice fed a low-fat diet with no added cholesterol. METHODS: Male and female low-density lipoprotein receptor-deficient mice were fed an open stock low-fat diet (10% of kcals from fat) for 2, 4, or 17 weeks...
October 2012: Gender Medicine
https://read.qxmd.com/read/22944562/h-y-antigen-in-kidney-transplant-does-gender-matter
#24
JOURNAL ARTICLE
Steven Wagner
No abstract text is available yet for this article.
October 2012: Gender Medicine
https://read.qxmd.com/read/22940276/impaired-health-related-quality-of-life-in-elderly-women-is-associated-with-multimorbidity-results-from-the-korean-national-health-and-nutrition-examination-survey
#25
JOURNAL ARTICLE
Kwang-Il Kim, Ju Hyun Lee, Cheol-Ho Kim
BACKGROUND: Multimorbidity is a common problem in elderly populations and is significantly associated with functional decline, disability, and mortality. However, the sex-specific characteristics of multimorbidity and its effect on patients' quality of life (QOL) have not been clearly established. METHODS: We analyzed the Korean National Health and Nutrition Examination Survey database. EuroQol 5D (a standardized health outcomes measurement instrument that includes 2 dimensions, the EuroQol 5 Dimension [EQ-5D] index score and the EuroQol visual analogue scale [EQ-VAS]) was used to evaluate QOL...
October 2012: Gender Medicine
https://read.qxmd.com/read/22906727/donor-recipient-sex-mismatch-in-kidney-transplantation
#26
JOURNAL ARTICLE
Jane C Tan, Jane P Kim, Glenn M Chertow, F Carl Grumet, Manisha Desai
BACKGROUND: The lack of reliable human proxies for minor (ie, non-HLA) histocompatibility loci hampers the ability to leverage these factors toward improving transplant outcomes. Despite conflicting reports of the effect of donor-recipient sex mismatch on renal allografts, the association between acute rejection of renal allografts and the development of human alloantibodies to the male H-Y antigen suggested to us that donor-recipient sex mismatch deserved re-evaluation. OBJECTIVE: To evaluate whether the relationships between donor sex and allograft failure differed by recipient sex...
October 2012: Gender Medicine
https://read.qxmd.com/read/22863843/dietary-genistein-induces-sex-dependent-effects-on-murine-body-weight-serum-profiles-and-vascular-function-of-thoracic-aortae
#27
JOURNAL ARTICLE
Layla Al-Nakkash, Joshua B Martin, David Petty, Shaina M Lynch, Cristina Hamrick, Dana Lucy, John Robinson, Amity Peterson, Leona J Rubin, Tom L Broderick
BACKGROUND: The influence on, or interaction of, sex and dietary genistein on serum markers of cardiovascular health and cardiovascular function remain unclear. OBJECTIVES: Our purpose was to examine the effects of a genistein-containing diet (600 mg/kg food) (600G) and a genistein-free diet (0G), on cardiovascular risk parameters of male and female mice. METHODS: C57BL/6J mice were fed the diets for 1 month, after which time blood pressure, serum markers, and in vitro vascular reactivity was measured...
October 2012: Gender Medicine
https://read.qxmd.com/read/22854101/analysis-of-sex-differences-in-preadmission-management-of-st-segment-elevation-stemi-myocardial-infarction
#28
COMPARATIVE STUDY
Marna Rayl Greenberg, Andrew C Miller, Richard S Mackenzie, David M Richardson, Amy M Ahnert, Mia J Sclafani, Jennifer L Jozefick, Terrence E Goyke, Valerie A Rupp, David B Burmeister
BACKGROUND: Many reports suggest gender disparity in cardiac care as a contributor to the increased mortality among women with heart disease. OBJECTIVE: We sought to identify gender differences in the management of Myocardial Infarction (MI) Alert-activated ST-segment elevation myocardial infarction (STEMI) patients that may have resulted from prehospital initiation. METHODS: A retrospective database was created for MI Alert STEMI patients who presented to the emergency department (ED) of an academic community hospital with 74,000 annual visits from April 2000 through December 2008...
October 2012: Gender Medicine
https://read.qxmd.com/read/22819558/sexual-dimorphism-in-development-of-kidney-damage-in-aging-fischer-344-rats
#29
COMPARATIVE STUDY
Jennifer M Sasser, Oladele Akinsiku, Natasha C Moningka, Katie Jerzewski, Chris Baylis, Amanda J LeBlanc, Lori S Kang, Amy L Sindler, Judy M Muller-Delp
BACKGROUND: Aging kidneys exhibit slowly developing injury and women are usually protected compared with men, in association with maintained renal nitric oxide. OBJECTIVES: Our purpose was to test 2 hypotheses: (1) that aging intact Fischer-344 (F344) female rats exhibit less glomerular damage than similarly aged males, and (2) that loss of female ovarian hormones would lead to greater structural injury and dysregulation of the nitric oxide synthase (NOS) system in aging F344 rat kidneys...
August 2012: Gender Medicine
https://read.qxmd.com/read/22795492/sex-differences-in-cardiovascular-disease-risk-in-adolescents-with-type-1-diabetes
#30
JOURNAL ARTICLE
Sowmya Krishnan, David A Fields, Kenneth C Copeland, Piers R Blackett, Michael P Anderson, Andrew W Gardner
BACKGROUND: Cardiovascular disease is seen at a younger age and at a higher prevalence in patients with type 1 diabetes than in the general population. It is well described that women with type 1 diabetes have a higher relative risk of cardiovascular disease than men with type 1 diabetes, unlike that seen in the general population. The pathophysiology behind this is unknown. OBJECTIVE: We performed a cross-sectional study to examine sex differences in cardiovascular disease risk factors in adolescents with type 1 diabetes between ages 13 and 20 years, compared with children of a similar age without type 1 diabetes...
August 2012: Gender Medicine
https://read.qxmd.com/read/22795464/sex-differences-in-hypertension-contribution-of-the-renin-angiotensin-system
#31
REVIEW
Christine Maric-Bilkan, Michaele B Manigrasso
Numerous studies have shown that female human beings exhibit lower blood pressure levels over much of their life span compared with their age-matched counterparts. This sexual dimorphism is apparent in human beings as well as most, if not all, mammals. However, after the onset of menopause blood pressure levels in women increase and become similar to those in men, suggesting an important role of sex hormones in the regulation of blood pressure. The lower blood pressure levels in premenopausal women are associated with a lower risk of development and progression of cardiovascular disease and hypertension compared with age-matched men...
August 2012: Gender Medicine
https://read.qxmd.com/read/22795463/sexual-dimorphism-in-urinary-angiotensinogen-excretion-during-chronic-angiotensin-ii-salt-hypertension
#32
JOURNAL ARTICLE
Vicky F Rands, Dale M Seth, Hiroyuki Kobori, Minolfa C Prieto
BACKGROUND: The intrarenal renin-angiotensin system contributes to hypertension by regulating sodium and water reabsorption throughout the nephron. Sex differences in the intrarenal components of the renin-angiotensin system have been involved in the greater incidence of high blood pressure and progression to kidney damage in males than females. OBJECTIVE: This study investigated whether there is a sex difference in the intrarenal gene expression and urinary excretion of angiotensinogen (AGT) during angiotensin II (Ang II)-dependent hypertension and high-salt (HS) diet...
August 2012: Gender Medicine
https://read.qxmd.com/read/22770654/human-papillomavirus-and-cervical-cancer-knowledge
#33
LETTER
D Nicole Defayette, L Lee Glenn
No abstract text is available yet for this article.
August 2012: Gender Medicine
https://read.qxmd.com/read/22763277/sex-differences-in-lung-gas-volumes-after-lipopolysaccharide-induced-chorioamnionitis-in-fetal-sheep
#34
JOURNAL ARTICLE
Verena A C Lambermont, Jasper V Been, Steffen Kunzmann, Sizzle F Vanterpool, John P Newnham, Suhas G Kallapur, Alan H Jobe, Boris W Kramer
BACKGROUND: Preterm female infants have a survival advantage and enhanced lung development, which is an important determinant of preterm survival. OBJECTIVE: Given the modulation of lung development by fetal exposure to infection/inflammation, we hypothesized that female fetuses have enhanced lung maturational responses to chorioamnionitis compared with male fetuses. METHODS: Time-pregnant ewes received intra-amniotic injections with saline (n = 60) or lipopolysaccharide (LPS) at 2 days (n = 30) or 7 days (n = 45) before surgical delivery at 123 to 125 days of gestation (term: ∼147 days)...
August 2012: Gender Medicine
https://read.qxmd.com/read/22748425/age-dependent-influence-of-gender-on-the-association-between-obesity-and-a-cluster-of-cardiometabolic-risk-factors
#35
COMPARATIVE STUDY
Ichiro Wakabayashi
BACKGROUND: Obesity is a main risk factor in metabolic syndrome. Gender is known to influence the risk of obesity and other cardiovascular risk factors. However, it remains to be determined whether there is a gender-specific difference in the relationship between obesity and accumulation of other cardiometabolic risk factors such as hypertension, dyslipidemia, and diabetes. OBJECTIVE: The aim of this study was to determine whether the association between obesity and a cluster of other cardiometabolic risk factors is modified by gender...
August 2012: Gender Medicine
https://read.qxmd.com/read/22728214/testosterone-levels-and-androgen-receptor-gene-polymorphism-predict-specific-symptoms-of-depression-in-young-men
#36
COMPARATIVE STUDY
Janani S Sankar, Elizabeth Hampson
BACKGROUND: Testosterone (T) has been hypothesized to modulate the expression of depressive symptoms in men; however, support for this proposition is mixed. OBJECTIVE: To investigate bioavailable T, measured from saliva, and androgen receptor gene (AR) polymorphism (the number of glutamine [CAG] repeats in exon 1 of AR) and their relation to discrete symptoms of depression in 150 men aged 17 to 27 years who varied in mood status from depressed to nondepressed. METHODS: Participants completed the Center for Epidemiologic Studies Depression Scale and the Patient Health Questionnaire-9...
August 2012: Gender Medicine
https://read.qxmd.com/read/22721599/biomarkers-for-abdominal-aortic-aneurysms-from-a-sex-perspective
#37
COMPARATIVE STUDY
Christina Villard, Dick Wågsäter, Jesper Swedenborg, Per Eriksson, Rebecka Hultgren
BACKGROUND: Abdominal aortic aneurysms (AAAs) differ in men and women. Women are older at diagnosis, have a higher risk of rupture, and worse outcome after surgery compared with men. The higher occurrence of AAAs in men accounts for the dominance of men in biomarker analyses. OBJECTIVE: The primary aim of this study was to investigate levels of established biomarkers for AAA in men and women, and the secondary aim was to compare biomarker levels in women with and without AAAs...
August 2012: Gender Medicine
https://read.qxmd.com/read/22626768/challenges-of-work-life-balance-for-women-physicians-mothers-working-in-leadership-positions
#38
JOURNAL ARTICLE
Claudia Schueller-Weidekamm, Alexandra Kautzky-Willer
BACKGROUND: Female leadership in medicine is still disproportionately small, which might be due to the barriers of combining work and family. OBJECTIVES: The aim of this study was, first, to perform a strengths, weakness, opportunities, and threats (SWOT) analysis and, second, to create a strategic concept for career development. METHODS: In this study, all women in leadership positions in the health care system in Vienna, Austria, with at least 1 child (n = 8), were interviewed about the advantages and disadvantages of gender with regard to career development, the strengths and weaknesses of female leadership, and their work-life balance...
August 2012: Gender Medicine
https://read.qxmd.com/read/22555015/age-dependent-reductions-in-mitochondrial-respiration-are-exacerbated-by-calcium-in-the-female-rat-heart
#39
JOURNAL ARTICLE
J Craig Hunter, Alexandra M Machikas, Donna H Korzick
BACKGROUND: Cardiovascular disease mortality increases rapidly after menopause by poorly defined mechanisms. OBJECTIVE: Because mitochondrial function and Ca(2+) sensitivity are important regulators of cell death after myocardial ischemia, we sought to determine whether aging and/or estrogen deficiency (ovariectomy) increased mitochondrial Ca(2+) sensitivity. METHODS: Mitochondrial respiration was measured in ventricular mitochondria isolated from adult (6 months; n = 26) and aged (24 months; n = 25), intact or ovariectomized female rats using the substrates α-ketoglutarate/malate (complex I); succinate/rotenone (complex II); ascorbate/N,N,N',N'-tetramethyl-p-phenylenediamine/antimycin (complex IV)...
June 2012: Gender Medicine
https://read.qxmd.com/read/22503604/diabetic-polyneuropathy-relates-to-bone-metabolism-and-markers-of-bone-turnover-in-elderly-patients-with-type-2-diabetes-greater-effects-in-male-patients
#40
COMPARATIVE STUDY
Sazan Rasul, Aysegul Ilhan, Ludwig Wagner, Anton Luger, Alexandra Kautzky-Willer
BACKGROUND: There is evidence that diabetic polyneuropathy (PNP) is associated with reduced bone mineral density (BMD) in type 1 diabetes but little is known about the impact of diabetic PNP on bone metabolism in type 2 diabetes. OBJECTIVES: The aim of this study was to evaluate differences in bone metabolism by measuring markers of bone turnover and BMD in men and postmenopausal women with type 2 diabetes and diabetic PNP compared with those without PNP. Gender differences were analyzed for both groups of patients...
June 2012: Gender Medicine
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