journal
https://read.qxmd.com/read/36864810/erosive-pustular-dermatosis-of-the-scalp-epds-a-case-series-and-short-review
#1
JOURNAL ARTICLE
U Wollina
Erosive pustular dermatosis of the scalp (EPDS) is an uncommon and possibly underreported chronic inflammatory skin disease within the spectrum of neutrophilic disorders. Although it has been reported in all ages, elderly people are more common affected. The surrounding skin often shows symptoms of chronic actinic damage. Histopathology is rather unspecific. The pustules and lakes of pus are sterile. Treatment includes anti-septic, anti-inflammatory topical therapy, in more severe cases oral steroids. Rarely systemic antibiosis or surgery are necessary...
January 2023: Georgian Medical News
https://read.qxmd.com/read/36864809/gayet-wernicke-s-encephalopathy-after-covid-19-in-elderly-subjects-in-tropical-environments-study-of-six-6-observations-in-conakry
#2
JOURNAL ARTICLE
M L Touré, G C Othon, A Touré, M Diakité, K Condé, D F Kassa, F Sakadi, D Camara, S Conde, V Millimono, M S Diallo, S M Diallo, J M Kadji, E Lamah, F A Cisse, A Cisse
In sub-Saharan Africa, the COVID-19 pandemic has caused severe malnutrition in elderly populations with the appearance of vitamin deficiencies, in particular thiamine responsible for Gayet Wernicke's encephalopathy (EGW). We present a series of six (6) patients hospitalized in the Neurology Department of the CHU Ignace Deen for the management of a brain syndrome with vigilance disorders after recovery from COVID-19, including oculomotor disorders, motor incoordination on a course of severe weight loss. The six patients underwent an evaluation of malnutrition by determining the WHO body mass index, the Detsky index, the serum albumin assay, the thiamine assay and a neuroradiological assessment (MRI) and an electroencephalogram (EEG) examination although this does not seem necessary for diagnosis...
January 2023: Georgian Medical News
https://read.qxmd.com/read/36864808/ultrastructural-features-of-the-rearrangement-of-the-cells-of-the-hematotesticular-barrier-and-the-spermatogenic-epithelium-of-the-rats-testicles-during-the-sudden-withdrawal-of-prednisolone-after-its-long-term-introduction-in-high-doses
#3
JOURNAL ARTICLE
I Herasymiuk, O Herman, O Ilkiv
With long-term use of hormonal drugs, according to the principle of "negative feedback", the production of own hormones by the endocrine glands is inhibited. With sudden withdrawal, in particular, of glucocorticoids, there are processes that threaten the development of secondary adrenal insufficiency. The purpose of the study: to establish the peculiarities of the reconstruction of the cellular elements of the testicles of white rats after the withdrawal of high doses of prednisolone. An ultrastructural study was performed on 60 male rats...
January 2023: Georgian Medical News
https://read.qxmd.com/read/36864807/integral-method-for-assessing-the-efficiency-of-dental-caries-prevention
#4
JOURNAL ARTICLE
A Zaitsev, N Ilenko-Lobach, O Boychenko, N Ilenko, A Krutikova, I Ivanitskyi, T Bublii, N Kotelevska
This is a part of research work of the Therapeutic Dentistry Department of the Poltava State Medical University (PSMU). The name of this research work is "Development of pathogenetic prevention of pathological changes in the oral cavity in patients with internal diseases" (state registration No. 0121U108263).
January 2023: Georgian Medical News
https://read.qxmd.com/read/36864806/the-existence-of-a-functional-matrix-in-the-development-of-the-facial-skeleton-in-children
#5
JOURNAL ARTICLE
N Makhlynets, H Prots, A Pantus, Z Ozhogan, L Plaviuk
Aim - identifying the relationship between the presence of oral habits and the violation of the formation of the facial skeleton in children. Improving the effectiveness of comprehensive treatment of patients with pathological occlusion and existing oral habits through orthodontic treatment and elimination of oral habits. We conducted clinical, radiological methods of examination of 60 patients 12-15 years old with acquired maxillomandibular anomalies and oral habits, 15 persons aged 12-15 years without maxillomandibular anomalies and acquired deformities (norm group)...
January 2023: Georgian Medical News
https://read.qxmd.com/read/36864805/epileptic-seizures-revealing-sturge-weber-s-disease-in-a-tropical-environment-study-of-eight-cases
#6
JOURNAL ARTICLE
M L Touré, G C Othon, S M Diallo, T H Baldé, S D Barry, M M Konaté, F Sakadi, F D Kassa, A Kourouma, J M Kadji, M Diakité, A Sakho, M T Diallo, S Condé, V Millimono, D Camara, H Madandi, T M Diallo, E Lamah, F A Cisse, A Cisse
In sub-Saharan Africa (SSA), the etiological factors of epilepsy are multiple and phacomatoses, in particular Sturge weber's disease, are rarely reported due to under-medicalization and insufficient multidisciplinary care. We carried out a retrospective study of 216 patients hospitalized for recurrent epileptic seizures between 2015 and 2022 in the neurology and pediatrics department of the University Hospital Center of Conakry, among whom eight (8) patients were identified for Sturge Weber's disease in order to reassess this pathology from a clinical and paraclinical point of view in a tropical environment...
January 2023: Georgian Medical News
https://read.qxmd.com/read/36864804/peculiarities-of-lipid-exchange-in-pregnant-women-with-obesity
#7
JOURNAL ARTICLE
F Tagiyeva
The high frequency of obstetric pathology is explained by the violation of adaptive and compensatory-protective mechanisms, the breakdown of the activity of regulatory systems that occur during obesity. Determining the levels and dynamics of changes in lipid metabolism during the gestation period in pregnant women with obesity is of particular interest. The purpose of this study was to evaluate the dynamics of lipid metabolism changes in pregnant women with obesity. The work is based on clinical-anthropometric and clinical-laboratory results of studies of 52 pregnant women with abdominal obesity (the main group)...
January 2023: Georgian Medical News
https://read.qxmd.com/read/36864803/the-nature-and-features-of-surrogacy-as-an-assisted-reproductive-technology
#8
JOURNAL ARTICLE
T Popovych, V Zaborovskyy, Ya Baryska, Z Pohoryelova, O Maslyuk
The purpose of the article is to analyze certain aspects of modern discourse concerning the nature of surrogacy and its features, including the outline of the main legal obligations arising from the surrogacy technology application. The methodological basis of this work is a system of methods, scientific approaches, techniques, and principles that were aimed at achieving the study objectives. Universal, general scientific and special legal methods were used. Thus, for example, the methods of analysis, synthesis, induction, and deduction allowed to generalize the acquired knowledge, which became the basis of scientific intelligence, while the comparative method allowed to explain the specifics of normative regulation of the studied issues in separate countries...
January 2023: Georgian Medical News
https://read.qxmd.com/read/36864802/myelodysplastic-syndrome-diagnosis-treatment-and-prognosis-literature-review
#9
JOURNAL ARTICLE
S Baidurin, Sh Akhmetzhanova, A Ilmalieva, G Sagyndykova, A Orazbekova
Given the difficulties of diagnosis, the absence of a typical clinical picture of myelodysplastic syndrome accompanied by cytopenia, a high risk of transformation into acute myeloid leukemia, discussion of the formation, terminology, pathogenesis, classification, clinical course and principles of management of this group of tumor diseases is very relevant. The review article discusses the issues of terminology, pathogenesis, classification and diagnosis of myelodysplastic syndrome (MDS), as well as the principles of management of this category of patients...
January 2023: Georgian Medical News
https://read.qxmd.com/read/36864801/comparative-results-of-modern-examination-methods-in-early-diagnosis-of-bladder-cancer-determination-of-the-degree-of-invasion-and-selection-of-radical-treatment-tactics
#10
JOURNAL ARTICLE
S Imamverdiyev, E Qasımov, R Naghıyev
This article deals with comparative results of modern examination methods in early diagnosis of bladder cancer, determination of the degree of invasion and selection of radical treatment tactics. The purpose of the conducted research work is to make a comparative analysis of existing methods of examination related to the stages of development of bladder cancer. The research was carried out on the Department of Urology of Azerbaijan Medical University. In this research work, an algorithm was developed by conducting a comparative analysis among modern methods of radiation examination (Ultrasound, CT, MRI) in determining the location of the tumor in the urethra, the position, size, direction of development and local prevalence of the process, analyzing the results obtained and trying to determine the sequence of profitable examinations for patients...
January 2023: Georgian Medical News
https://read.qxmd.com/read/36864800/er22-23ek-and-tth111i-polymorphisms-in-the-glucocorticoid-receptor-gene-in-patients-with-bronchial-asthma-with-regard-to-the-age-of-onset
#11
JOURNAL ARTICLE
V Kachkovska, A Kovchun, V Kovchun, I Klisch, O Marchuk, I Dudchenko, L Prystupa
The objective of the study was to evaluate the frequency of the ER22/23EK and Tth111I polymorphisms in the glucocorticoid receptor gene (GR) in patients with early-onset and late-onset asthma (BA) and to assess the risk of its phenotype's development. We examined 553 BA patients and 95 apparently healthy individuals. The patients were divided into 2 groups depending on the age of BA onset: Group I included 282 patients with late-onset asthma, and group II included 271 patients with early-onset asthma. The ER22/23EK (rs 6189/6190) and Tth111I (rs10052957) polymorphisms in the GR gene were determined using polymerase chain reaction-restriction fragment length polymorphism analysis...
January 2023: Georgian Medical News
https://read.qxmd.com/read/36864799/clinical-and-functional-assessment-of-the-early-postoperative-outcome-of-surgical-treatment-of-patients-with-vestibular-schwannoma
#12
JOURNAL ARTICLE
O Skobska, O Zemskova, O Lisianyi, S Andrieiev, S Levcheniuk, M Khinikadze
The incidence of vestibular schwannoma (VS) increased largely within the last 50 years from 1,5 cases per 100 thousand persons to 4,2 (for the last decade). The approaches to the management of VS patients vary significantly in different medical centers and different countries. The search for the consensus in selecting strategy of VS treatment based on systemic clinical-and-functional assessment of treatment outcome is topical nowadays. The aim of study - to analyze the clinical-and-functional early postoperative outcome of the surgical treatment of vestibular schwannoma depending on the stage of the disease...
January 2023: Georgian Medical News
https://read.qxmd.com/read/36864798/karapandzic-flap-for-squamous-cell-carcinoma-of-the-lower-lipp-potential-role-of-nitrosamines-in-eprosartan-as-cancer-triggering-factors
#13
JOURNAL ARTICLE
G Tchernev, I Lozev, I Pidakev, S Kordeva
Chronic alcohol use, smoking, poor dental hygiene, absorbed sun radiation over the years, fair skin (Fitzpatrick type 1), light eyes, painful sunburns, congenital or acquired immunosuppression, certain rare syndromes, as well as infections with human papillomaviruses are perceived as risk factors for the development of squamous cell carcinoma of the lips. The new and at the same time modern aspects involving the pathogenesis of keratinocyte tumors in practice prove to be quite problematic for both patients and clinicians...
January 2023: Georgian Medical News
https://read.qxmd.com/read/36864797/characteristics-of-the-autonomic-nervous-system-state-assessed-by-the-heart-rate-variability-study-in-cirrhotic-patients-with-syntropic-cardiomyopathy-and-its-features-depending-on-the-qt-interval-duration
#14
JOURNAL ARTICLE
Z Bilous, O Abrahamovych, M Abrahamovych, O Fayura, A Fedets
The patients with liver cirrhosis (LC) have autonomic nervous system (ANS) imbalance that can be evaluated by the heart rate variability (HRV) study. ANS imbalance results into cirrhotic cardiomyopathy (CCMP) and the most easily diagnosed feature of CCMP is the prolonged QT interval. Usually, in the literature not all HRV parameters are characterized, or their assessment period is short, not allowing covering all the important moments and therefore needing further study. In a randomized way with the preliminary stratification by the presence of LC 33 patients after signing the informed consent were examined...
January 2023: Georgian Medical News
https://read.qxmd.com/read/36864796/assessment-of-risk-factors-of-myocardial-infarction-in-young-persons
#15
JOURNAL ARTICLE
D Nurkina, M Baimuratova, L Zhussupbekova, A Kodaspayev, S Alimbayeva
In terms of morbidity and mortality, cardiovascular illnesses are the main cause of death worldwide. Half of all noncommunicable diseases on the earth are caused by them. Due to the steadily rising mortality rates from circulatory diseases in Kazakhstan, our region was identified as having a high cardiovascular risk in 2021 when the updated Score 2 (Systematic COronary Risk Evaluation) scale was developed. There has been a recent increase in this pathology's prevalence among younger people (up to 44 years)...
January 2023: Georgian Medical News
https://read.qxmd.com/read/36864795/health-related-quality-of-life-among-patients-with-osteoarthritis-a-cross-sectional-study
#16
JOURNAL ARTICLE
Z Thabit, H Al-Qazaz
Osteoarthritis (OA) is a chronic disease characterized by the collapse or destruction of the cartilage that covers the ends of the bone in the joints. Health-related quality of life (QoL) is a multidimensional concept that includes aspects of social, emotional, mental, and physical functioning. This study aimed to evaluate the quality of life among patients with OA. A cross-section study takes place in Mosul city with a sample of 370 patients aged 40 years and older included. The data collection form consisted of personnel with demographic and socioeconomic information, comprehension of the OA symptoms, and QoL scale...
January 2023: Georgian Medical News
https://read.qxmd.com/read/36864794/assessment-of-coronary-collateral-circulation-predictors-among-patients-with-acute-coronary-syndrome-in-population-georgia
#17
JOURNAL ARTICLE
M Chigogidze, Z Pagava, I Taboridze, N Lomia, G Saatashvili, N Sharashidze
Coronary collateral circulation (CCC) has been shown to have a prognostic role in acute myocardial infarction (MI). We aimed to identify factors associated with CCC development in patients with acute myocardial ischemia. In the present analysis, 673 consecutive patients aged 27 - 94 years (64.7±11.48) with acute coronary syndrome (ACS), who underwent coronary angiography within the first 24 hours after symptom onset were included. Baseline data, including sex, age, cardiovascular risk factors, medication, antecedent angina, prior coronary revascularization, EF%, blood pressure levels were obtained from patient medical records...
January 2023: Georgian Medical News
https://read.qxmd.com/read/36864793/specificities-of-the-course-of-subclinical-hepatitis-among-young-adults-with-acuie-glomerulonephritis
#18
JOURNAL ARTICLE
M Sargsyan
In spite of the progress in medical science in our country during recent years, the investigation of some problems of development and course of acute glomerulonephritis (AG) particularly in young adults remains topical. In this paper we discuss classical types of AG in young adults, when the intake of paracetamol and diclofenac led to a dysfunctional and organic liver injury, at the same time it negatively affected the course of AG. Goal - assessment of cause-and-effect relations of renal and liver injuries in young adults with acute glomerulonephritis...
January 2023: Georgian Medical News
https://read.qxmd.com/read/36864792/smoking-jeopardized-mitochondrial-function-vitiating-lipid-profile
#19
JOURNAL ARTICLE
R Mohammad, M Al Kattan
Smoking has increasingly reported as deleterious behavior associated with serious problems, ranging from mood changes to cancer. The basic and common landmark associated with these disorders is derangement of mitochondrial quasi-equilibrium. This study aimed to identify the role of smoking in modulation of lipid profile in the view of mitochondrial dysfunctionality. To do so, smokers were recruited, serum lipid profile, serum pyruvate, and serum lactate were determined to confirm the link between serum lipid profile and smoking induced lactate to pyruvate ratio...
January 2023: Georgian Medical News
https://read.qxmd.com/read/36864791/characteristics-of-calcium-phosphorus-metabolism-and-bone-turnover-indicators-in-patients-with-liver-cirrhosis-and-their-diagnostic-value-for-assessing-bone-structures-disorder
#20
JOURNAL ARTICLE
N Drobinska, O Abrahamovych, M Abrahamovych, R Ivanochko, V Chemes
Information about calcium-phosphorus metabolism (CPM) and bone turnover in patients with liver cirrhosis (LC), as well as clarifying their diagnostic value for assessing bone structure disorder, will help doctors to detect their lesions in timely manner and, based on the information received, to choose well-founded comprehensive treatment strategy. Aim - to characterize the indicators of calcium-phosphorus metabolism and bone turnover in patients with liver cirrhosis, and to find out their diagnostic value for detecting bone structure disorder...
January 2023: Georgian Medical News
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