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Kathmandu University Medical Journal (KUMJ)

B Bajracharya, P Poudel, D Bajracharya, S Bhattacharyya, P Shakya
Eosinophilic Granuloma is the mildest and localized form of Langerhans Cell Histiocytosis and is characterized by clonal proliferation of Langerhans cells. It is a rare disease, accounting for less than 1% of all the osseous neoplasms. It has predilection for the axial skeleton and incidence in jaws is just 7.9%. It lacks pathognomonic clinical and radiographic trait and hence is difficult to make a correct diagnosis without histopathological and immunohistochemical examination. This report describes a case of Eosinophilic Granuloma of mandible in 30 years old male who presented with complain of unhealed extraction wound and was clinically diagnosed as chronic suppurative osteomyelitis...
April 2018: Kathmandu University Medical Journal (KUMJ)
L K Rajbanshi
Delayed presentation of congenital diphragmatic hernia is a rare condition which can present in later stage of life either with the nonspecific complains or acute complians of shortness of breath. The clinical features and the radiological findings can be confused with pneumothorax leading to inadvertant insertion of chest tube. Immediate and accurate diagnosis of the condition is required for the better outcome. Our case is an example of the condition where a patient presenting with features similar to pneumotharax without history of trauma ,the diagnosis of congenital diaphragmatic hernia should always be considerd...
April 2018: Kathmandu University Medical Journal (KUMJ)
L Thapa, R Amatya, S Maharjan, N Gaurishankar, A M Shrestha, S Bhattarai, S N Singh, D N Gongal, U P Devkota
Cheiro-Oral Syndrome (COS) is a very rare neurological syndrome associated with varied etiology. We report a 53-year-old man presented with left sided perioral and ipsilateral hand/fingers burning sensation for a one-month duration. On examination, he had hypesthesia over left perioral and distal palmar aspect of all five fingers. MRI revealed subacute infarct in the posterior limb of right internal capsule adjacent to and minimally involving thalamus. He was diagnosed as CheiroOral Syndrome as a result of ischemic stroke and managed...
April 2018: Kathmandu University Medical Journal (KUMJ)
P Baral
Dorsal Metacarpophalyngeal joint dislocation of thumb in children is a rare occurrence. All the three different types, namely Simple Complete, Complex Complete and Incomplete dislocations have been described in this article with clinical and radiological clues to differentiate the closely reducible (simple) dislocations from irreducible ones (complex). A simple approach to treatment decision making has been adopted for all cases, starting with attempt of closed reduction which if fails, moving to open reduction...
April 2018: Kathmandu University Medical Journal (KUMJ)
D K Thapa, D Visentin, R Kornhaber, M Cleary
Background There has been limited research into the prevalence of mental disorders amongst older adults in developing countries. Developing countries such as Nepal are undergoing significant demographic changes with an increasing number and proportion of older persons. Objective This systematic review reports the prevalence of mental health disorders amongst the elderly in Nepal. Method Databases searched were PubMed, CINAHL, Scopus and PsycINFO. A hand search for relevant articles appearing in reference lists and previously identified research was also undertaken...
April 2018: Kathmandu University Medical Journal (KUMJ)
R Shrestha, R Shrestha, S Thapa, S K Khadka, D Shrestha
Background Knee pain is one of the common complaints patients present with in any community based health camps and Osteoarthritis of knee is a usual diagnosis. Injecting a long acting steroid is a common practice to alleviate the symptoms of osteoarthritic knee. Objective To evaluate the clinical outcome of injecting Triamcinolone acetenoid in osteoarthritis of knee in a community set up over a randomized double-blind placebo control trial. Method A prospective, randomized, double blind, placebo control trial was carried out in community after obtaining the ethical clearance from the IRC...
April 2018: Kathmandu University Medical Journal (KUMJ)
Y Gautam, M Bade
Background It is a well known fact that phases of respiration cause change in heart rate and autonomic tone of the heart. But how cardiovascular autonomic reflexes affect the electrocardiographic Heart rate-corrected QT interval (QTc) during the inspiratory and expiratory phase of respiration also need to be established. Objective To determine whether the respiratory phases influence the QTc interval or not. Method This was a quantitative, observational, cross-sectional study done at Kathmandu University School of Medical Sciences, Pre-Clinical Basic Science Block, Chaukot...
April 2018: Kathmandu University Medical Journal (KUMJ)
N Bhandari, R Prajapati
Background Breast feeding is the priceless gift given by mother to her newborn. It also has benefits to both mothers and baby. Prevalence of exclusive breast feeding varies from 26.4% in one study to that of 82.2% in another study. Objective To assess the factors associated with exclusive breast feeding among mothers. Method A prospective cross-sectional study using systematic random sampling method, was carried out in Dhulikhel Municipality for two months in November and December 2017 after taking permission from KUSMS IRC and from Dhulikhel Municipality...
April 2018: Kathmandu University Medical Journal (KUMJ)
S Marahatta, S Agrawal, K D Mehata
Background Alopecia areata (AA) is one of the non-scarring alopecia. Its etiology has not been well established till date. The most convincing hypothesis is autoimmune process for its causation. Amongst all, most frequent association was found with thyroid disorder. Objective To study the association of thyroid dysfunction in patients with alopecia areata. Method All patients of alopecia areata attending dermatology outpatient department and currently not receiving any treatment for alopecia areata were enrolled in the study...
April 2018: Kathmandu University Medical Journal (KUMJ)
O Nepal, R K Jha, A Bhattarai, P Khadka, B K Kapoor
Background Sympathetic arousal response due to rewarding emotion may not be considered threat to the well-being but such arousal response evoked by fear or punishment can be stressful. When such changes are recorded in lab as biological signals, induced with appropriate stimulus, the observed response may serve as a good indicator of homeostatic alteration. In this study, skin conductance was utilized to record sympathetic response for cognitive load, by application of simple subtraction task. Objective To detect sympathetic arousal by utilization of galvanic skin response during mental arithmetic task...
April 2018: Kathmandu University Medical Journal (KUMJ)
K R Sharma, P Bhandari, N Adhikari, P Tripathi, S Khanal, B R Tiwari
Background Multidrug resistant in clinical bacterial isolates has increasingly been reported through out the world and is associated with high morbidity, mortality and increased health care costs. It is important to determine the status of multidrug resistance pattern to understand the current resistance trend so that appropriate antibiotics can be used in practice. Objective To determine the antibiotic resistant profile and prevalence of extended spectrum β-lactamase producing multidrug resistant strains in pediatric patients of Kanti Children's Hospital, Kathmandu, Nepal...
April 2018: Kathmandu University Medical Journal (KUMJ)
S Pokhrel Ghimire S
Background Rupture uterus is associated with significant maternal and perinatal mortality and morbidity. Etiologies of uterine rupture are changing with time. There has been shift in etiology from an obstructed labour and multiparity towards rupture of a caesarean section scar. There is paucity of studies regarding this changing paradigm. Objective To study the changing etiological pattern of rupture uterus. Method We retrospectively analysed details of all patients with ruptured gravid uterus from Medical records of Nobel Medical College from 2013 July 1 to 2015 June 30...
April 2018: Kathmandu University Medical Journal (KUMJ)
S Sanjel, S N Khanal, S M Thygerson, K Khanal, Z D Pun, S Lama, S K Joshi
Background Workers in the brick manufacturing industries require to carry heavy loads, do repetitive work and remain in awkward postures for extended periods of time. These activities may cause them to develop work-related musculoskeletal symptoms and disorders. Objective To investigate the epidemiology of musculoskeletal symptoms and disorders among brick manufacturing workers as well as similar exposure groups among brick kiln workers. Method An analytical cross-sectional study was conducted during February - March 2015 in the Kathmandu Valley...
April 2018: Kathmandu University Medical Journal (KUMJ)
S Shakya Shrestha, K Risal, R Shrestha, R D Bhatta
Background Non-adherence to medication in hypothyroid patients leads to poor clinical outcome and increased health care costs. Study related to adherence to levothyroxine in hypothyroid patients is limited worldwide. Objective To determine the adherence pattern and factors affecting adherence in hypothyroid patients and compare the clinical outcomes among adherent and non-adherent patients. Method A cross-sectional study was conducted in Dhulikhel hospital, Kathmandu University hospital. Patients with hypothyroidism on levothyroxine fulfilling the inclusion criteria were enrolled in this study...
April 2018: Kathmandu University Medical Journal (KUMJ)
R Shrestha, H K Gupta, R R Hamal, R Pandit
Background Neck-shaft angle (NSA) is one of the prominent features in the proximal femur which is an important determinant of fracture of femoral neck. Present study evaluating the value of neck-shaft angle has relied heavily on radiographs. As knowledge of neck-shaft angle is important to orthopaedic surgeons, there is need to elucidate whether there is significant variation of this angle among the two different genders and various age groups of both right and left femora of Nepalese population. Objective To ascertain the value of neck-shaft angle in the Nepalese population by means of a radiographic study and to correlate the values with regard to right neck-shaft angle/ left neck-shaft angle side (RNSA/LNSA), gender and three different age group...
April 2018: Kathmandu University Medical Journal (KUMJ)
R Shresha, D Shrestha, R Kayastha
Background Pain after root canal therapy is unwanted yet common experience for the patient and unpleasant for the dentist so it is always desirable to predict such pain. Objective To evaluate the frequency, intensity and associated factors of post-operative pain after single visit endodontic therapy on teeth with vital pulps. Method A total of 418 single visit root canal treatments were performed on patients of age 18 years and above by two endodontists. Canals were shaped with rotary ProTaper files. After the canal preparation, the canals were obturated, using lateral compaction technique, with ProTaper universal gutta-percha and AH-Plus sealer...
April 2018: Kathmandu University Medical Journal (KUMJ)
R Kaiti, A Pradhan, H N Dahal, P Shrestha
Background Uncorrected refractive error is one of the most important causes of visual impairment worldwide. Objective To ascertain the pattern and prevalence of refractive error and secondary visual impairment in subjects attending Ophthalmology department. Method A prospective hospital-based study was designed where presenting visual acuity, age of presentation, refractive status, best corrected visual acuity and status of visual impairment were assessed in participants, ages ranging from 3-39 years presenting to the Ophthalmology department of Dhulikhel Hospital, Kathmandu University Hospital...
April 2018: Kathmandu University Medical Journal (KUMJ)
F Thermann, R M Karmacharya
Background Crural bypass surgery is one of the last options to salvage the leg. Compared to arterial reconstructions of more proximal localization patency rates are generally less good. The aim of this retrospective study was to answer the question if crural bypass surgery is justified. For that we focused on different technicalities, bypass material, recipient vessel and anticoagulation regimes. Objective To know outcome of crural bypass in terms of patency rates, survival rates, amputation. The difference in outcome is compared in different stages of peripheral arterial disease and various bypass materials and sites...
April 2018: Kathmandu University Medical Journal (KUMJ)
Eachempati Prashanti
No abstract text is available yet for this article.
April 2018: Kathmandu University Medical Journal (KUMJ)
R M Karmacharya, B Shrestha, B K Shrestha, M Devbhandari, S M Tuladhar, A Hodde, F Thermann
Varicose vein, one of the common vascular illnesses is usually a disease in lower limb. This is due to reflux of blood from deep venous system to superficial venous system. Rarely, this disease can also happen in veins in different location. Four such rare encounters are mentioned in this case series.
January 2018: Kathmandu University Medical Journal (KUMJ)
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