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Esophagus: Official Journal of the Japan Esophageal Society

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https://read.qxmd.com/read/30771041/validation-of-new-japanese-classification-system-for-esophageal-achalasia
#1
Ryo Kato, Kiyokazu Nakajima, Tsuyoshi Takahashi, Koji Tanaka, Yasuhiro Miyazaki, Tomoki Makino, Yukinori Kurokawa, Makoto Yamasaki, Masaki Mori, Yuichiro Doki
BACKGROUND: The fourth edition of New Japanese classification system for esophageal achalasia was revised after a long interval of 30 years in 2012. In this new system, achalasia is morphologically classified into 3 types, based on its X-ray findings. However, the system has been limitedly used in Japan and has not been fully validated in terms of its predictive capability of postoperative outcomes. The purpose of this study was to clarify the validity of new Japanese classification system for esophageal achalasia, as an index of patient characteristics and as a predictor of operative and mid/long-term postoperative outcomes...
February 15, 2019: Esophagus: Official Journal of the Japan Esophageal Society
https://read.qxmd.com/read/30771040/surgical-management-and-prognostic-factors-in-esophageal-perforation-caused-by-foreign-body
#2
Yiwei Huang, Tao Lu, Yu Liu, Cheng Zhan, Di Ge, Lijie Tan, Qun Wang
OBJECTIVES: Esophageal perforation is associated with multiple serious complications and high mortality. Herein, we identify some predictors for postoperative outcomes, compare the outcomes of various surgical approaches, and summarize our experience with esophageal perforation over the past 13 years. METHODS: We retrospectively analyzed 38 patients diagnosed with esophageal perforation caused by foreign body between November 2004 and May 2018. Univariate analysis and multivariate logistic regression analysis were performed to identify potential risk factors related to prognosis...
February 15, 2019: Esophagus: Official Journal of the Japan Esophageal Society
https://read.qxmd.com/read/30737707/a-feasibility-study-of-mediastinoscopic-radical-esophagectomy-for-thoracic-esophageal-cancer-from-the-viewpoint-of-the-dissected-mediastinal-lymph-nodes-validated-with-thoracoscopic-procedure-a-prospective-clinical-trial
#3
Yutaka Tokairin, Yasuaki Nakajima, Kenro Kawada, Akihiro Hoshino, Takuya Okada, Tairo Ryotokuji, Taichi Ogo, Masafumi Okuda, Yuichiro Kume, Yudai Kawamura, Kazuya Yamaguchi, Kagami Nagai, Tatsuyuki Kawano, Yusuke Kinugasa
PURPOSE: A prospective trial evaluated the feasibility and safety of "mediastinoscopic esophagectomy with lymph node dissection" (MELD). METHODS: Eligible patients had thoracic esophageal squamous cell carcinoma, excluding T4, a bulky primary lesion or distant metastasis. Ten patients were enrolled and treated between September 2015 and March 2018. Additionally, to verify the integrity of the mediastinal lymph node dissection, thoracoscopic observation and lymph node dissection were followed...
February 8, 2019: Esophagus: Official Journal of the Japan Esophageal Society
https://read.qxmd.com/read/30600487/oral-cryotherapy-for-prophylaxis-of-oral-mucositis-caused-by-docetaxel-cisplatin-and-fluorouracil-chemotherapy-for-esophageal-cancer
#4
Koichi Okamoto, Itasu Ninomiya, Takahisa Yamaguchi, Shiro Terai, Shinichi Nakanuma, Jun Kinoshita, Isamu Makino, Keishi Nakamura, Tomoharu Miyashita, Hidehiro Tajima, Hiroyuki Takamura, Sachio Fushida, Tetsuo Ohta
BACKGROUND: Chemotherapy, including preoperative chemotherapy, plays an important role in the treatment of esophageal cancer. However, although docetaxel, cisplatin, and fluorouracil (DCF) therapy has a powerful antitumor effect, the associated adverse events make it difficult to maintain the patient's general condition. Oral mucositis is an important adverse effect of chemotherapy, and its severity, frequency, and impact on patient quality of life should not be underestimated. This study evaluated the role of oral cryotherapy for prophylaxis of oral mucositis caused by DCF therapy...
January 1, 2019: Esophagus: Official Journal of the Japan Esophageal Society
https://read.qxmd.com/read/30600486/efficacy-of-on-demand-therapy-using-20-mg-vonoprazan-for-non-erosive-reflux-disease
#5
Yoshimasa Hoshikawa, Noriyuki Kawami, Shintaro Hoshino, Tomohide Tanabe, Mariko Umezawa, Mitsuru Kaise, Katsuhiko Iwakiri
BACKGROUND: To evaluate the efficacy of on-demand therapy using 20-mg vonoprazan for non-erosive reflux disease. METHODS: On-demand therapy by taking one 20-mg tablet of vonoprazan only when reflux symptoms occurred was performed for 8 weeks by 30 patients (11 men, mean age: 67.8) with non-erosive reflux disease who responded well to maintenance therapy using proton pump inhibitor and answered "very satisfied" or "satisfied" to an overall satisfaction survey (5-grade scale)...
January 1, 2019: Esophagus: Official Journal of the Japan Esophageal Society
https://read.qxmd.com/read/30600485/efficacy-and-safety-of-endoscopic-resection-for-gastric-tube-cancer-after-surgical-resection-of-esophageal-squamous-cell-carcinoma
#6
Yoshie Hirayama, Junko Fujisaki, Shoichi Yoshimizu, Yusuke Horiuchi, Toshiyuki Yoshio, Akiyoshi Ishiyama, Toshiaki Hirasawa, Yu Imamura, Shinji Mine, Masayuki Watanabe, Tomohiro Tsuchida
BACKGROUND: Gastric tube cancers (GTCs) are found frequently, even as the surgical outcomes of esophageal cancer improve. Diagnosing and treating early gastric tube cancer endoscopically has therefore become very important. AIMS: This study aimed to evaluate the clinical characteristics and outcomes of endoscopic resection for GTC. METHODS: We analyzed 29 patients (33 lesions) with metachronous GTC who underwent endoscopic resection from April 2005 to August 2016 and evaluated their clinical characteristics and the short-term outcomes of endoscopic resection...
January 1, 2019: Esophagus: Official Journal of the Japan Esophageal Society
https://read.qxmd.com/read/30547352/diagnosis-using-deep-learning-artificial-intelligence-based-on-the-endocytoscopic-observation-of-the-esophagus
#7
Youichi Kumagai, Kaiyo Takubo, Kenro Kawada, Kazuharu Aoyama, Yuma Endo, Tsuyoshi Ozawa, Toshiaki Hirasawa, Toshiyuki Yoshio, Soichiro Ishihara, Mitsuhiro Fujishiro, Jun-Ichi Tamaru, Erito Mochiki, Hideyuki Ishida, Tomohiro Tada
BACKGROUND AND AIMS: The endocytoscopic system (ECS) helps in virtual realization of histology and can aid in confirming histological diagnosis in vivo. We propose replacing biopsy-based histology for esophageal squamous cell carcinoma (ESCC) by using the ECS. We applied deep-learning artificial intelligence (AI) to analyse ECS images of the esophagus to determine whether AI can support endoscopists for the replacement of biopsy-based histology. METHODS: A convolutional neural network-based AI was constructed based on GoogLeNet and trained using 4715 ECS images of the esophagus (1141 malignant and 3574 non-malignant images)...
December 13, 2018: Esophagus: Official Journal of the Japan Esophageal Society
https://read.qxmd.com/read/30519821/current-status-of-esophageal-endoscopy-including-the-evaluation-of-smoking-and-alcohol-consumption-in-japan-an-analysis-based-on-the-japan-endoscopy-database
#8
Chikatoshi Katada, Takahiro Horimatsu, Manabu Muto, Kiyohito Tanaka, Koji Matsuda, Mitsuhiro Fujishiro, Yutaka Saito, Kazuo Ohtsuka, Ichiro Oda, Masayuki Kato, Mitsuhiro Kida, Kiyonori Kobayashi, Shu Hoteya, Shinya Kodashima, Takahisa Matsuda, Hironori Yamamoto, Shomei Ryozawa, Ryuichi Iwakiri, Hiromu Kutsumi, Hiroaki Miyata, Mototsugu Kato, Ken Haruma, Kazuma Fujimoto, Naomi Uemura, Michio Kaminishi, Hisao Tajiri
PURPOSE: The aim was to investigate the current status of esophageal endoscopy, including the evaluation of smoking and alcohol consumption, in Japan. METHODS: A total of 47,441 patients who underwent 69,748 sessions of esophageal endoscopy were registered in the Japan Endoscopy Database between January 2015 and March 2017. The study variables were as follows: (1) methods for monitoring the esophagus and the time required for monitoring and (2) the status of smoking and alcohol consumption in patients with esophageal cancer and head and neck cancer...
December 5, 2018: Esophagus: Official Journal of the Japan Esophageal Society
https://read.qxmd.com/read/30370453/clinical-endoscopic-and-histologic-characteristics-of-lymphocytic-esophagitis-a-systematic-review
#9
REVIEW
Mohamad Habbal, Michael A Scaffidi, Amir Rumman, Rishad Khan, Mirusha Ramaj, Ahmed Al-Mazroui, Michael J Abunassar, Thurarshen Jeyalingam, Akshay Shetty, Gabor P Kandel, Catherine J Streutker, Samir C Grover
OBJECTIVE: Lymphocytic esophagitis (LyE) is a novel, yet poorly described, clinicopathologic entity. The aim of this systematic review was to characterize the demographic, clinical, endoscopic, and histologic features of LyE in observational studies of adult and pediatric patients. DESIGN: We searched the Embase, MEDLINE, and SCOPUS databases for relevant studies in 2018. Two authors reviewed and extracted data from studies that met the inclusion and exclusion criteria...
October 29, 2018: Esophagus: Official Journal of the Japan Esophageal Society
https://read.qxmd.com/read/30341631/one-year-outcomes-in-children-with-eosinophilic-esophagitis
#10
Matea Kovačić, Josipa Unić, Zrinjka Mišak, Oleg Jadrešin, Vlatka Konjik, Sanja Kolaček, Iva Hojsak
BACKGROUND AND AIMS: Despite rising incidence of eosinophilic esophagitis (EoE), data on the follow-up and treatment outcomes in pediatric patients are scarce. Therefore, the aim of this study was to present data on the treatment outcomes in children diagnosed with EoE who were treated in a tertiary medical center. PATIENTS AND METHODS: A retrospective study involving patients younger than 18 years who were diagnosed with EoE in our center between January 2011 and June 2017...
October 19, 2018: Esophagus: Official Journal of the Japan Esophageal Society
https://read.qxmd.com/read/30327893/barrett-s-esophagus-is-negatively-associated-with-eosinophilic-esophagitis-in-japanese-subjects
#11
Shingo Takashima, Fumio Tanaka, Koji Otani, Shuhei Hosomi, Yasuaki Nagami, Noriko Kamata, Koichi Taira, Hirokazu Yamagami, Tetsuya Tanigawa, Shinya Fukumoto, Toshio Watanabe, Yasuhiro Fujiwara
BACKGROUND: Although both eosinophilic esophagitis (EoE) and Barrett's esophagus (BE) are considered to be associated with T helper (Th) 2-mediated immune responses, the association between EoE and BE is unclear. We investigated the clinical relationship between EoE and BE. METHODS: We conducted a single-center retrospective observational study. The study included 95 patients with EoE and randomly selected age- and sex-matched controls who underwent esophagogastroduodenoscopy during a medical health check-up at Osaka City University in a ratio of 1:2 for comparison...
October 16, 2018: Esophagus: Official Journal of the Japan Esophageal Society
https://read.qxmd.com/read/30324431/appropriateness-of-the-institute-certification-system-for-esophageal-surgeries-by-the-japan-esophageal-society-evaluation-of-survival-outcomes-using-data-from-the-national-database-of-hospital-based-cancer-registries-in-japan
#12
Satoru Motoyama, Eri Maeda, Masahiko Yano, Takushi Yasuda, Masaichi Ohira, Yuichiro Doki, Yasushi Toh, Takahiro Higashi, Hisahiro Matsubara
BACKGROUND: Since 2013, The Japan Esophageal Society has been certifying "Authorized Institute for Board Certified Esophageal Surgeon (AIBCES)" to contribute to improving national medical care by enhancing the professional knowledge and skills of esophageal surgeons. However, the appropriateness on this certification system has not yet been verified. Our aim was to assess the appropriateness of the institute certification system for esophageal surgeries used by the medical society...
October 15, 2018: Esophagus: Official Journal of the Japan Esophageal Society
https://read.qxmd.com/read/30311102/the-impact-of-geriatric-nutritional-risk-index-on-surgical-outcomes-after-esophagectomy-in-patients-with-esophageal-cancer
#13
Naoshi Kubo, Katsunobu Sakurai, Tatsuro Tamura, Takahiro Toyokawa, Hiroaki Tanaka, Kazuya Muguruma, Masakazu Yashiro, Masaichi Ohira
BACKGROUND: Geriatric Nutritional Index (GNRI) was shown to be closely associated with nutrition-related complications and mortality in elderly hospitalized patients. Impact of GNRI on postoperative outcomes in surgically treated esophageal squamous cell carcinoma (ESCC) patients has not been evaluated extensively. METHODS: A total of 240 patients with ESCC who underwent radical esophagectomy with two- or three-field lymphadenectomy between April 2000 and April 2012 were included in this retrospective study...
October 11, 2018: Esophagus: Official Journal of the Japan Esophageal Society
https://read.qxmd.com/read/30225745/the-effect-of-an-elemental-diet-on-oral-mucositis-of-esophageal-cancer-patients-treated-with-dcf-chemotherapy-a-multi-center-prospective-feasibility-study-epoc-study
#14
Yoshihiro Tanaka, Takao Ueno, Naoya Yoshida, Yasunori Akutsu, Hiroya Takeuchi, Hideo Baba, Hisahiro Matsubara, Yuko Kitagawa, Kazuhiro Yoshida
PURPOSE: Oral mucositis (OM) is one of the most uncomfortable adverse events experienced by cancer patients undergoing chemotherapy. Previous reports have revealed that the oral administration of an elemental diet (ED) may prevent OM. However, the incidence of OM has not been accurately determined by specialized diagnostic methods and the effects of an ED on OM remain unclear. We investigated the dose that could feasibly be administered and its effects with regard to the suppression of OM in esophageal cancer patients undergoing chemotherapy...
October 2018: Esophagus: Official Journal of the Japan Esophageal Society
https://read.qxmd.com/read/30225744/association-of-level-of-anastomosis-and-anastomotic-leak-after-esophagectomy-in-anterior-mediastinal-reconstruction
#15
Katsunori Nishikawa, Tetsuji Fujita, Yako Hasegawa, Yujiro Tanaka, Akira Matsumoto, Norio Mitsumori, Katsuhiko Yanaga
AIM: The purpose of this study was to investigate modifiable predisposing factors associated with anastomotic leak in the anterior mediastinal (AM) reconstruction route. METHODS: We reviewed the data on 154 patients who underwent esophagectomy and gastric tube reconstruction using the AM route between 2008 and 2016. The data included computed tomography (CT) scans with sagittal reconstruction of the thoracic section. The level of the esophagogastric anastomosis (LEA) and pretracheal distance (PTD) was measured from sagittal reconstructed CT images...
October 2018: Esophagus: Official Journal of the Japan Esophageal Society
https://read.qxmd.com/read/30225743/lateral-thermal-spread-and-recurrent-laryngeal-nerve-paralysis-after-minimally-invasive-esophagectomy-in-bipolar-vessel-sealing-and-ultrasonic-energy-devices-a-comparative-study
#16
Kazuo Koyanagi, Fumihiko Kato, Keita Nakanishi, Soji Ozawa
BACKGROUND: This study aimed to compare the extent of lateral thermal spread of surrounding tissues after the use of advanced bipolar and ultrasonic coagulation and shearing devices. Association between recurrent laryngeal nerve paralysis (RLNP) and such devices was assessed in patients who underwent minimally invasive esophagectomy (MIE). METHODS: LigaSure™ (LS) and Sonicision™ (SONIC) were used. In ex vivo experiments using the porcine muscle, blade temperature and tissue temperature were measured using a thermometer after the activation of both devices...
October 2018: Esophagus: Official Journal of the Japan Esophageal Society
https://read.qxmd.com/read/30225742/involved-field-chemoradiotherapy-for-postoperative-solitary-lymph-node-recurrence-of-esophageal-cancer
#17
Terufumi Kawamoto, Keiji Nihei, Keisuke Sasai, Katsuyuki Karasawa
BACKGROUND: For patients with postoperative lymph node (LN) recurrent esophageal cancer, the appropriate irradiation field in chemoradiotherapy (CRT) remains controversial. We assessed the clinical outcomes and prognostic factors related to involved-field CRT for postoperative solitary LN recurrence of esophageal squamous cell carcinoma (ESCC). METHODS: We retrospectively evaluated 21 patients who had received curative resection, with LN recurrence of ESCC. Patients received CRT using 5-fluorouracil plus cisplatin or docetaxel, prescribed at 60 Gy in 30 fractions...
October 2018: Esophagus: Official Journal of the Japan Esophageal Society
https://read.qxmd.com/read/30225741/surgical-results-of-laparoscopic-toupet-fundoplication-for-gastroesophageal-reflux-disease-with-special-reference-to-recurrence
#18
Nobuo Omura, Fumiaki Yano, Kazuto Tsuboi, Masato Hoshino, SeRyung Yamamoto, Shunsuke Akimoto, Takahiro Masuda, Hideyuki Kashiwagi, Katsuhiko Yanaga
BACKGROUND: Surgical results of GERD have mainly been reported from the Western countries, with a few reports found in Japan. We examined the surgical results of laparoscopic Toupet fundoplication and clarify the characteristics of recurrent cases. METHODS: The subjects included 375 patients who underwent laparoscopic Toupet fundoplication from June 1997 to December 2016 as the initial surgery. Patient characteristics, pathophysiology, and surgical results were examined...
October 2018: Esophagus: Official Journal of the Japan Esophageal Society
https://read.qxmd.com/read/30225740/hyponatremia-in-patients-with-esophageal-cancer-treated-with-chemotherapy-including-cisplatin
#19
Ayako Shimada, Hiroya Takeuchi, Kazumasa Fukuda, Koichi Suda, Rieko Nakamura, Norihito Wada, Hirofumi Kawakubo, Yuko Kitagawa
BACKGROUND: Little is known about hyponatremia in patients with esophageal cancer treated with cisplatin-based chemotherapy. The aim of this study was to analyze the risk factors for hyponatremia and its effect on outcomes in patients with esophageal cancer treated with chemotherapy including cisplatin. METHODS: We retrospectively analyzed the records of 137 patients with esophageal cancer who received chemotherapy including cisplatin for the first time between January 2011 and December 2014...
October 2018: Esophagus: Official Journal of the Japan Esophageal Society
https://read.qxmd.com/read/30225739/impact-of-reflux-esophagitis-on-the-esophageal-function-before-and-after-laparoscopic-fundoplication
#20
Masato Hoshino, Nobuo Omura, Fumiaki Yano, Kazuto Tsuboi, Se Ryung Yamamoto, Shunsuke Akimoto, Takahiro Masuda, Hideyuki Kashiwagi, Katsuhiko Yanaga
BACKGROUND: High-resolution manometry (HRM), which is breakthrough testing equipment to evaluate esophageal motor function, was developed in Europe and United State and has garnered attention. Moreover, multichannel intraluminal impedance pH (MII-pH) testing has allowed us to grasp all liquid/gas reflux including not only acid but also non-acid reflux. We examined the impact of the presence of reflux esophagitis (RE) on esophageal motor function before and after laparoscopic fundoplication...
October 2018: Esophagus: Official Journal of the Japan Esophageal Society
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