Heart Rhythm : the Official Journal of the Heart Rhythm Society

BACKGROUND: The influence of hemodynamic parameters on the recurrence of atrial fibrillation (AF) following catheter ablation is not well known, and it remains unclear whether a nomogram combining risk factors and hemodynamic parameters improves prediction accuracy. OBJECTIVE: This study aimed to develop a nomogram based on echocardiographic hemodynamic parameters for predicting AF recurrence following catheter ablation in non-valvular atrial fibrillation (NVAF)...

BACKGROUD: Left bundle branch pacing (LBBP) is a novel physiological pacing modality. However, whether it delivers comparable efficacy with different capture sites in heart failure (HF) patients remains unclear. OBJECTIVE: This study aims to assess the association between different pacing sites and the response of LBBP . METHODS: Forty-three consecutive HF patients , referred for successful LBBP implantation, were prospectively recruited in this study...

BACKGROUND: Normally-functioning implantable cardioverter-defibrillators (ICDs) with intact lead systems occasionally fail to deliver therapy for ventricular tachycardia/ fibrillation (VT/VF) or deliver it only after clinically-significant delays ("failure-to-treat"). OBJECTIVE: To investigate ICD failure-to-treat VT/VF in a large patient cohort. METHODS: We searched the United States (US) Food and Drug Association's online Manufacturer and User Facility Device Experience (MAUDE) database from 2019 to 2023 for manufacturer-verified reports in which normally-functioning ICDs failed to treat VT/VF...

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BACKGROUND: Conduction system pacing (CSP) has emerged as an alternative therapy to traditional right ventricular (RV) pacing. However, the majority of CSP studies reflect small cohorts or single-center experience. OBJECTIVE: This analysis compared CSP to dual-chamber (DC) RV pacing in a large, population-based cohort utilizing data from the Micra Coverage with Evidence Development (CED) study. METHODS: Medicare administrative claims data were used to identify patients implanted with a DC RV pacemaker...

BACKGROUND: Epicardial Marshall bundle (MB) are frequently utilized in left atrial tachycardias (LATs) post atrial fibrillation (AF) ablation with pulmonary vein isolation and substrate modification. OBJECTIVE: This study sought to classify different activation patterns of MB mediated LATs and the corresponding electrophysiological characteristics. METHODS: From 2019 to 2021, 28 cases of atrial tachycardias（ATs）post-AF-ablation were diagnosed as MB-mediated LATs by ultra-high density mapping and entrainment...

BACKGROUND: Sleep-disordered breathing (SDB) increases the risk of cardiac arrhythmias and sudden cardiac death. OBJECTIVE: To characterize the associations between SDB, intermittent hypoxemia, and the beat-to-beat QT variability index (QTVI), a measure of ventricular repolarization lability associated with cardiac arrhythmias and sudden cardiac death. METHODS: Three distinct cohorts were used: (1) a matched sample of 122 participants with and without severe SDB for cross-sectional analysis, (2) a matched sample of 52 participants with and without incident SDB for longitudinal analysis, and (3) a sample of 19 healthy adults exposed to acute intermittent hypoxia and ambient air on two separate days...

BACKGROUND: Current guidelines present varying classes of recommendations for implantable cardioverter-defibrillator (ICD) utilization in patients with cardiac sarcoidosis (CS) and left ventricular ejection fraction (LVEF) <50%. OBJECTIVE: To investigate the ventricular arrhythmia risk in CS patients with ICDs and varying degrees of LV systolic dysfunction. METHODS: We included CS patients with an ICD and LVEF <50% at index evaluation...

BACKGROUND: Leadless left ventricular (LV) endocardial pacing is an emerging cardiac resynchronization therapy (CRT) technology. Predictors of response to leadless CRT are poorly understood. Implanting the LV endocardial pacing electrode in sites with increased electrical latency (Q-LV) may improve response rates. OBJECTIVE: To examine the association between Q-LV and echocardiographic remodelling response to leadless CRT delivered with the WiSE-CRT system. METHODS: A post-hoc analysis (n=122) of the SOLVE-CRT trial examined the relationship between LV pacing site Q-LV with rate of LV end-systolic volume (LVESV) reduction >15% at 6 months...

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Traditional classifications categorize atrial fibrillation (AF) into paroxysmal, persistent or permanent, but recent advancements in monitoring have revealed AF as a continuous variable, challenging existing paradigms. AF burden, defined basically as the amount of time spent in AF during a monitored period, has emerged as a crucial metric. This review assesses the evolving landscape of AF burden and its measurement methods, diagnostic modalities, and impact on outcomes. Guidelines suggest individualized approaches, combining AF burden with clinical scores (CHA2 DS2 -VASc), but recent studies have challenged this...

BACKGROUND: Atrial fibrillation (AF) is an age-related disorder closely linked to autonomic nervous system dysfunction. Neurofilament light chain (NFL) protein is a biomarker for neurodegenerative diseases. OBJECTIVE: This study aims to evaluate the predictive value of NFL in forecasting AF recurrence following ablation. METHODS: We included patients initially diagnosed with AF who underwent catheter ablation. Serum NFL levels were measured using an enzyme-linked immunosorbent assay...

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BACKGROUND: Cardiac implantable electronic device (CIED) procedures can cause significant post-operative pain. Opioid use for post-operative pain is associated with risk of persistent use. The benefits of pectoral nerve blocks (PECs) have been established for other chest wall surgeries but adoption in electrophysiology has been limited. OBJECTIVES: To evaluate the efficacy of intraoperative ultrasound guided PECs performed at the time of CIED procedures by the implanting physician from within the device pocket...

No abstract text is available yet for this article.

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No abstract text is available yet for this article.