Hao Zhang, Jiao Jiao, Tianheng Zhao, Enshuang Zhao, Lanhui Li, Guihua Li, Borui Zhang, Qing-Ming Qin
Rice blast, caused by Magnaporthe oryzae(M.oryzae), is a destructive rice disease that reduces rice yield by 10% to 30% annually. It also affects other cereal crops such as barley, wheat, rye, millet, sorghum, and maize. Small RNAs (sRNAs) play an essential regulatory role in fungus-plant interaction during the fungal invasion, but studies on pathogenic sRNAs during the fungal invasion of plants based on multi-omics data integration are rare. This paper proposes a novel approach called Graph Embedding combined with Random Walk with Restart (GERWR) to identify pathogenic sRNAs based on multi-omics data integration during M...
December 28, 2023: IEEE/ACM Transactions on Computational Biology and Bioinformatics