journal
https://read.qxmd.com/read/37731293/serum-immunoglobulin-g-level-reduction-is-a-predictor-of-short-term-improvement-in-patients-with-myasthenia-gravis-undergoing-plasmapheresis
#1
JOURNAL ARTICLE
Shingo Konno, Toshiki Fujioka
OBJECTIVES: The aim of the study was to investigate the serological factors in predicting symptom improvement in myasthenia gravis (MG) patients who underwent plasmapheresis (PP). METHODS: The relationship between symptom improvement and change in immunoglobin G (IgG) and acetylcholine receptor antibody (AchR-Ab) levels in 21 MG patients after PP was analyzed. RESULTS: Patients were divided into two groups: the favorable (n = 11) or unfavorable (n = 10) response groups around the median MG composite improvement rate (50 [29, 56]%) 2 weeks after a PP course...
September 20, 2023: Therapeutic Apheresis and Dialysis
https://read.qxmd.com/read/37731171/eligibility-test-for-advanced-chronic-kidney-disease-revision-and-proposal
#2
REVIEW
Rebeca García Agudo, Marina Méndez Molina, Sara Piqueras Sánchez, Antonio Tejera-Muñoz
Nowadays, chronic kidney disease (CKD) prevalence keeps increasing worldwide. The management of these patients usually requires renal replacement therapy (RRT). However, the complexity of patients' profiles comprises a great challenge to overcome. During the last decades, CKD units have been developed to offer multidisciplinary and coordinated attention to patients, helping in the decision-making of the RRT. Nevertheless, there is a huge variability in the performance and organization of care practice, implying an existing necessity to homogenize the RRT modality chosen...
September 20, 2023: Therapeutic Apheresis and Dialysis
https://read.qxmd.com/read/37728048/covid-19-is-more-lethal-in-hemodialysis-chronic-kidney-disease-patients-with-low-physical-capacity
#3
JOURNAL ARTICLE
Rafael B Orcy, Caroline C Bluhm, Larissa R Ribeiro, Priscila M Sosa, Bianca D Correa, Franklin C Barcellos, Maristela Böhlke
INTRODUCTION: The mortality rate in patients on maintenance hemodialysis (HD) is high and is associated with low functional capacity (FC). We analyzed the association of FC and COVID-19 lethality among HD patients. METHODS: A cohort study that included evaluations of FC in patients on HD was underway, and the association between FC and lethality was included as an ad-hoc outcome. RESULTS: One hundred and twelve patients were submitted to a physical, 31 patients contracted symptomatic COVID-19, 20 recovered and 11 died (lethality rate of 35...
September 20, 2023: Therapeutic Apheresis and Dialysis
https://read.qxmd.com/read/37724487/comparative-outcomes-of-hemodialysis-patients-facing-pre-omicron-and-omicron-covid-19-epidemics
#4
JOURNAL ARTICLE
Hiroko Beppu, Tatsuya Fukuda, Naoya Otsubo, Taro Akihisa, Tomoko Kawanishi, Toshie Ogawa, Yasutomo Abe, Mariko Endo, Tomohide Hanawa, Chise Sugita, Yoshiaki Kikkawa, Tetsuya Yamada, Sachiko Wakai
INTRODUCTION: This study elucidates factors affecting the severity and mortality in pre-Omicron and Omicron strains of SARS-CoV-2 and vaccination impact. METHODS: This single-center retrospective observational study included 1598 hospitalized COVID-19 patients. Patients were grouped into "pre-Omicron" and "Omicron" periods. The endpoint was severe COVID-19 (oxygen saturation [SpO2 ] < 94%). Logistic regression examined associations between clinical factors, including hemodialysis (HD), and the endpoint...
September 19, 2023: Therapeutic Apheresis and Dialysis
https://read.qxmd.com/read/37704402/association-between-serum-sodium-and-28-day-mortality-in-sepsis-patients-a-secondary-data-analysis-from-three-large-critical-illness-cohorts
#5
JOURNAL ARTICLE
Wei Li, Shuwen Li, Jia Yuan, Xianjun Chen, Qimin Chen, Chuan Xiao, Qing Li, Lu Li, Ying Liu, Juan He, Lu Chen, Feng Shen
OBJECTIVE: The present study was designed to explore the association between serum sodium and mortality in patients with sepsis by using a large sample, multicenter MIMIC-IV database. METHODS: We extracted the data of 34 925 sepsis patients from the retrospective cohort mimicIV database. After adjusting the confounders, we explored the independent effects of serum sodium on 28-day mortality. RESULTS: A nonlinear relationship existed between serum sodium and 28-day mortality, of which a negative association was found between serum sodium and 28-day mortality (odds ratio: 0...
September 13, 2023: Therapeutic Apheresis and Dialysis
https://read.qxmd.com/read/37697687/the-addition-of-cytosorb-in-patients-on-va-ecmo-improves-urinary-output-and-icu-survival
#6
JOURNAL ARTICLE
Daniel Lovrić, Marijan Pašalić, Stefan Križanac, Karla Kovačić, Boško Skorić, Hrvoje Jurin, Davor Miličić, Vedran Premužić
INTRODUCTION: The aim of this study was to analyze the efficiency of CytoSorb adsorber in patients presenting with cardiogenic shock and treated with venoarterial extracorporeal membrane oxygenation (VA-ECMO). METHODS: Sixteen patients put on VA ECMO due to cardiogenic shock were included, stratified according to the use of Cytosorb adsorber in the first 24 h and compared across different clinical outcomes. RESULTS: Significantly lower vasopressor doses were required among patients treated with Cytosorb at the initiation and before weaning from ECMO...
September 11, 2023: Therapeutic Apheresis and Dialysis
https://read.qxmd.com/read/37691116/the-relationship-between-dietary-inflammatory-index-and-bone-mineral-density-in-ckd-patients
#7
JOURNAL ARTICLE
Wenhui Wu, Xiurong Li, Jia Di, Hua Zhou, Hongyan Niu, Lu Chen, Qi Sha, Min Yang
INTRODUCTION: Chronic systemic inflammation was proposed as a critical factor in the development of osteoporosis. We aim to investigate the effect of the DII on bone mineral density (BMD) in CKD patients. METHODS: 2276 participants from NHANES were enrolled. The DII score was calculated based on a single 24-h dietary recall. Total BMD was measured using Dual-energy x-ray absorptiometry. A multiple-stepwise linear regression model was used to determine associations between BMD and DII in CKD patients...
September 10, 2023: Therapeutic Apheresis and Dialysis
https://read.qxmd.com/read/37691018/what-is-photopheresis-role-of-extracorporeal-photopheresis-in-the-treatment-of-gvhd-and-its-practice-in-sweden
#8
LETTER
Yoshimi Fukumaki Karlsson, Gösta Berlin
No abstract text is available yet for this article.
September 10, 2023: Therapeutic Apheresis and Dialysis
https://read.qxmd.com/read/37667594/management-of-dialysis-patients-with-hepatitis-c-virus-in-the-era-of-direct-acting-antiviral-therapy
#9
LETTER
Michel Jadoul, Laura Labriola
No abstract text is available yet for this article.
September 4, 2023: Therapeutic Apheresis and Dialysis
https://read.qxmd.com/read/37649446/retrospective-observational-study-of-changes-in-serum-cytokines-and-adiponectin-with-continuous-plasma-exchange-with-dialysis-therapy-for-severe-covid-19
#10
JOURNAL ARTICLE
Yuya Suzuki, Hajime Nakae, Kasumi Satoh, Nobuhisa Hirasawa, Komei Kameyama, Yasuhito Irie, Toshiharu Kitamura, Tasuku Nara, Kyohei Maeno, Kenji Yoshida, Manabu Okuyama
INTRODUCTION: Coronavirus disease 2019 (COVID-19) is associated with a marked increase in the inflammatory cytokines, IL-6 and IL-18. Blood purification therapy aimed at controlling cytokines is one treatment option; however, evidence of its effectiveness is needed. Plasma exchange with dialysis (PED) is a blood purification method involving selective plasma exchange with dialysate flowing through the outer hollow fiber of the plasma separator. In this retrospective study, we investigated the efficacy of continuous PED (cPED) over 48 h in five patients with severe COVID-19...
August 31, 2023: Therapeutic Apheresis and Dialysis
https://read.qxmd.com/read/37649130/correction-to-impact-of-weekly-teriparatide-on-the-bone-and-mineral-metabolism-in-hemodialysis-patients-with-relatively-low-serum-parathyroid-hormone-a-pilot-study
#11
(no author information available yet)
No abstract text is available yet for this article.
August 30, 2023: Therapeutic Apheresis and Dialysis
https://read.qxmd.com/read/37646345/the-role-of-plasmapheresis-in-severe-acute-disseminated-encephalomyelitis-with-clinical-findings-of-transverse-myelitis
#12
JOURNAL ARTICLE
Olivia W Fjellbirkeland, Wladimir M Szpirt, Malene L Børresen
INTRODUCTION: Acute disseminated encephalomyelitis is a rare acute demyelinating disease of the central nervous system (CNS). The pathogenesis remains unclear but is suspected to be autoimmune. High doses of methylprednisolone (HDMP) are currently considered standard of treatment. Plasmapheresis (PE) is typically given in steroid refractory cases. There is currently limited evidence supporting its use in ADEM. MATERIALS AND METHODS: We report a 16-year-old girl with ADEM who improved rapidly after initiating PE...
August 30, 2023: Therapeutic Apheresis and Dialysis
https://read.qxmd.com/read/37641163/plasma-exchange-in-neurology-patients-experience-from-single-center-in-montenegro
#13
JOURNAL ARTICLE
Milovan Roganovic, Jevto Erakovic, Ljiljana Radulovic, Slavisa Perunicic, Dragica Milikic, Balsa Vujovic, Zilha Idrizovic, Sandra Vujovic, Mladen Debeljevic, Sanja Gluscevic
INTRODUCTION: Plasma exchange (PE) is widely used in many immune-based neurological diseases. Our aim is to analyze characteristics of PE in neurological patients at the Clinical Center of Montenegro. METHODS: Our study involved neurological patients treated with PE between January 2020 and April 2022. RESULTS: In total, 246 PEs were performed in 43 patients. We divided patients into 4 groups according to indications. In 8/9 multiple sclerosis (MS) patients a decrease of Expanded Dysability Status Scale at least 0...
August 28, 2023: Therapeutic Apheresis and Dialysis
https://read.qxmd.com/read/37641162/phosphate-kinetic-modeling-as-an-estimate-of-daily-ingested-phosphate-in-hemodialysis-patients-with-or-without-residual-kidney-function
#14
JOURNAL ARTICLE
Emad Samaan, Mohammed Nagah, Ghada El Said
BACKGROUND AND AIM: Daugirdas suggested a 2-pool phosphate kinetic model based on his previously established urea kinetic model. The current study aims to assess the level of agreement between the modeled daily ingested phosphorus (DIP) values and the routine method of dietary recall calculations in hemodialysis patients. METHOD: The study was conducted on 100 hemodialysis patients; 50 were anuric, and the others had residual kidney function (RKF). The level of correlation and agreement between the dietary calculated and modeled DIP were assessed in both study groups...
August 28, 2023: Therapeutic Apheresis and Dialysis
https://read.qxmd.com/read/37635386/the-effect-of-video-based-fistula-care-education-on-hemodialysis-patients-self-care-behaviors-a-randomized-controlled-study
#15
JOURNAL ARTICLE
Seda Şahan, Ayşegül Yıldız, Cevriye Özdemir, Elif Günay İsmailoğlu
OBJECTIVE: This study aimed to determine the effect of face-to-face and video-based education for fistula care on hemodialysis patients' self-care behaviors. METHODS: The study was conducted as a randomized controlled experimental study. Accordingly, 60 patients were included in the study for 95% strength. Fistula care training was given to the patients in the control group using face-to-face education technique. Fistula care training was given to the patients in the experimental group using a video-based technique...
August 27, 2023: Therapeutic Apheresis and Dialysis
https://read.qxmd.com/read/37632328/rescue-plan-for-capd-peritonitis-using-ultrasonography-as-a-guide-on-when-to-remove-the-catheter
#16
JOURNAL ARTICLE
Dusit Lumlertgul, Nantawan Tinroongroj, Suthaporn Lumlertgul, Pannamart Siwapitak, Rattanaluck Tungkanakorn, Supaporn Kaewpanya
INTRODUCTION: Ultrasound has been found to facilitate early identification of peritonitis in patients undergoing continuous ambulatory peritoneal dialysis (CAPD). METHODS: A retrospective analysis was carried out to evaluate the effectiveness of ultrasonography-guided removal of the Tenckhoff catheter in reducing complications like a shift to hemodialysis or death in CAPD patients. RESULTS: The "peritonitis rescue plan" supported timely decision-making for the removal of the infected catheter and resulted in a lower peritonitis episode per patient per month ratio (from 1:36 to 1:122) in 2021, a lower death rate (from 19% to 6...
August 26, 2023: Therapeutic Apheresis and Dialysis
https://read.qxmd.com/read/37605563/short-term-efficacy-and-tolerability-of-rheocarna-a-novel-direct-hemoperfusion-adsorptive-column-for-chronic-limb-threatening-ischemia-in-dialysis-patients-a-single-center-case-series
#17
JOURNAL ARTICLE
Eri Imai, Shuzo Kaneko, Ainori Hoshimoto, Rina Hisada, Makiko Harano, Emi Anno, So Hagiwara, Shunsuke Ozaki, Hiroko Torii, Yusuke Tsukamoto
INTRODUCTION: With population aging and lifestyle changes, the number of patients with chronic limb-threatening ischemia (CLTI) is increasing, and refractory or recurrent lesions are more common, especially in chronic dialysis patients. In March 2021, a new type of adsorptive cellulose bead column immobilized with dextran sulfate and L-tryptophan for direct hemoperfusion (DHP) was approved by Japan's medical insurance system as a treatment for CLTI. METHODS: We retrospectively analyzed 17 cases of CLTI in dialysis patients treated with DHP using the novel column (Rheocarna) (DHP-R) at our hospital from May 2021 to October 2022...
August 21, 2023: Therapeutic Apheresis and Dialysis
https://read.qxmd.com/read/37605348/experience-with-pre-diluted-plasma-exchange-therapy-for-hyperviscosity-syndrome
#18
JOURNAL ARTICLE
Shigeyuki Igarashi, Yasutaka Kamikawa, Syuji Ono, Gakuya Maekawa, Hiroyuki Kishigami, Kazuki Kawamura, Takumi Oonogi, Toshihiko Nagano
INTRODUCTION: Plasma exchange therapy (PE) is useful for patients with primary macroglobulinemia and multiple myeloma who present with hyperviscosity syndrome. However, hyperviscous blood may coagulate in the circuit during treatment, and in that case necessitate discontinuation of the treatment. This time, we report that we were able to prevent coagulation in the circuit by adding some ideas during the membrane separation method. METHODS: Physiological saline is injected in front of the plasma separation membrane to pre-dilute the blood, followed by filtration through the plasma separation membrane...
August 21, 2023: Therapeutic Apheresis and Dialysis
https://read.qxmd.com/read/37596836/glasgow-prognostic-score-as-an-outcome-predictor-for-patients-initiating-hemodialysis
#19
JOURNAL ARTICLE
Gabriel Ștefan, Adrian Zugravu, Simona Stancu
INTRODUCTION: This retrospective study examined the relationship between the Glasgow Prognostic Score (GPS) at hemodialysis (HD) initiation and overall/cardiovascular mortality. METHODS: A total of 264 patients starting HD between 2014 and 2015 at a single center were studied. Follow-up persisted until therapy change, death, or study end (December 31, 2021), with a median of 6.8 years. RESULTS: Patients with a higher GPS more frequently had emergent HD initiation and showed increased eGFR at initiation...
August 19, 2023: Therapeutic Apheresis and Dialysis
https://read.qxmd.com/read/37596835/effects-of-n-acetyl-l-tryptophan-on-desorption-of-the-protein-bound-uremic-toxin-indoxyl-sulfate-and-effects-on-uremic-sarcopenia
#20
JOURNAL ARTICLE
Atsushi Ohashi, Masashi Nakatani, Hideo Hori, Shigeru Nakai, Kunihiro Tsuchida, Midori Hasegawa, Naotake Tsuboi
INTRODUCTION: Indoxyl sulfate (IS) is a protein-bound uremic toxin that causes uremic sarcopenia. IS has poor dialysis clearance; however, the addition of a binding competitor improves its removal efficiency. METHODS: Dialysis experiments were performed using N-acetyl-l-tryptophan (L-NAT) instead of l-tryptophan (Trp) using pooled sera obtained from dialysis patients. The molecular structures of L-NAT and Trp were similar to that of IS. Therefore, we examined whether Trp and L-NAT were involved in muscle atrophy in the same manner as IS by performing culture experiments using a human myotube cell line...
August 19, 2023: Therapeutic Apheresis and Dialysis
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