Arianna Ericka Gómez, Sumaya Addish, Kurtis Alvarado, Priscilla Boatemaa, Anne C Onyali, Emily G Ramirez, Maria F Rojas, Jyoti Rai, Kiana A Reynolds, W Joyce Tang, Ronald Young Kwon
PURPOSE OF REVIEW: Chromosome region 7q31.31, also known as the CPED1-WNT16 locus, is robustly associated with BMD and fracture risk. The aim of the review is to highlight experimental studies examining the function of genes at the CPED1-WNT16 locus. RECENT FINDINGS: Genes that reside at the CPED1-WNT16 locus include WNT16, FAM3C, ING3, CPED1, and TSPAN12. Experimental studies in mice strongly support the notion that Wnt16 is necessary for bone mass and strength...
March 21, 2023: Current Osteoporosis Reports