journal
Journals Birth Defects Research. Part C...

Birth Defects Research. Part C, Embryo Today : Reviews

https://read.qxmd.com/read/27028846/membrane-mediated-regulation-of-embryonic-development-highlights
#21
JOURNAL ARTICLE
Rocky C Tuan
No abstract text is available yet for this article.
March 2016: Birth Defects Research. Part C, Embryo Today: Reviews
https://read.qxmd.com/read/26992153/membrane-dynamics-in-mammalian-embryogenesis-implication-in-signal-regulation
#22
REVIEW
Yoh Wada, Ge-Hong Sun-Wada, Nobuyuki Kawamura, Jyunichiro Yasukawa
Eukaryotes have evolved an array of membrane compartments constituting secretory and endocytic pathways that allow the flow of materials. Both pathways perform important regulatory roles. The secretory pathway is essential for the production of extracellular, secreted signal molecules, but its function is not restricted to a mere route connecting intra- and extracellular compartments. Post-translational modifications also play an integral function in the secretory pathway and are implicated in developmental regulation...
March 2016: Birth Defects Research. Part C, Embryo Today: Reviews
https://read.qxmd.com/read/26992081/membrane-mediated-regulation-of-vascular-identity
#23
REVIEW
Takuya Hashimoto, Masayuki Tsuneki, Trenton R Foster, Jeans M Santana, Hualong Bai, Mo Wang, Haidi Hu, Jesse J Hanisch, Alan Dardik
Vascular diseases span diverse pathology, but frequently arise from aberrant signaling attributed to specific membrane-associated molecules, particularly the Eph-ephrin family. Originally recognized as markers of embryonic vessel identity, Eph receptors and their membrane-associated ligands, ephrins, are now known to have a range of vital functions in vascular physiology. Interactions of Ephs with ephrins at cell-to-cell interfaces promote a variety of cellular responses such as repulsion, adhesion, attraction, and migration, and frequently occur during organ development, including vessel formation...
March 2016: Birth Defects Research. Part C, Embryo Today: Reviews
https://read.qxmd.com/read/26991990/from-embryonic-development-to-human-diseases-the-functional-role-of-caveolae-caveolin
#24
REVIEW
Jihee Sohn, Rachel M Brick, Rocky S Tuan
Caveolae, an almost ubiquitous, structural component of the plasma membrane, play a critical role in many functions essential for proper cell function, including membrane trafficking, signal transduction, extracellular matrix remodeling, and tissue regeneration. Three main types of caveolin proteins have been identified from caveolae since the discovery of caveolin-1 in the early 1990s. All three (Cav-1, Cav-2, and Cav-3) play crucial roles in mammalian physiology, and can effect pathogenesis in a wide range of human diseases...
March 2016: Birth Defects Research. Part C, Embryo Today: Reviews
https://read.qxmd.com/read/26991887/membrane-mediated-development-of-the-vertebrate-blood-gas-barrier
#25
REVIEW
Andrew N Makanya
During embryonic lung development, establishment of the gas-exchanging units is guided by epithelial tubes lined by columnar cells. Ultimately, a thin blood-gas barrier (BGB) is established and forms the interface for efficient gas exchange. This thin BGB is achieved through processes, which entail lowering of tight junctions, stretching, and thinning in mammals. In birds the processes are termed peremerecytosis, if they involve cell squeezing and constriction, or secarecytosis, if they entail cutting cells to size...
March 2016: Birth Defects Research. Part C, Embryo Today: Reviews
https://read.qxmd.com/read/26989869/ion-currents-in-embryo-development
#26
REVIEW
Elisabetta Tosti, Raffaele Boni, Alessandra Gallo
Ion channels are proteins expressed in the plasma membrane of electrogenic cells. In the zygote and blastomeres of the developing embryo, electrical modifications result from ion currents that flow through these channels. This phenomenon implies that ion current activity exerts a specific developmental function, and plays a crucial role in signal transduction and the control of embryogenesis, from the early cleavage stages and during growth and development of the embryo. This review describes the involvement of ion currents in early embryo development, from marine invertebrates to human, focusing on the occurrence, modulation, and dynamic role of ion fluxes taking place on the zygote and blastomere plasma membrane, and at the intercellular communication between embryo cell stages...
March 2016: Birth Defects Research. Part C, Embryo Today: Reviews
https://read.qxmd.com/read/26969610/molecular-mechanisms-of-membrane-interaction-at-implantation
#27
REVIEW
Lien M Davidson, Kevin Coward
Successful pregnancy is dependent upon the implantation of a competent embryo into a receptive endometrium. Despite major advancement in our understanding of reproductive medicine over the last few decades, implantation failure still occurs in both normal pregnancies and those created artificially by assisted reproductive technology (ART). Consequently, there is significant interest in elucidating the etiology of implantation failure. The complex multistep process of implantation begins when the developing embryo first makes contact with the plasma membrane of epithelial cells within the uterine environment...
March 2016: Birth Defects Research. Part C, Embryo Today: Reviews
https://read.qxmd.com/read/26598285/gestational-surrogacy-and-the-role-of-routine-embryo-screening-current-challenges-and-future-directions-for-preimplantation-genetic-testing
#28
REVIEW
E Scott Sills, Robert E Anderson, Mary McCaffrey, Xiang Li, Nabil Arrach, Samuel H Wood
Preimplantation genetic screening (PGS) is a component of IVF entailing selection of an embryo for transfer on the basis of chromosomal normalcy. If PGS were integrated with single embryo transfer (SET) in a surrogacy setting, this approach could improve pregnancy rates, minimize miscarriage risk, and limit multiple gestations. Even without PGS, pregnancy rates for IVF surrogacy cases are generally satisfactory, especially when treatment utilizes embryos derived from young oocytes and transferred to a healthy surrogate...
March 2016: Birth Defects Research. Part C, Embryo Today: Reviews
https://read.qxmd.com/read/26706413/the-microbiome-and-childhood-diseases-focus-on-brain-gut-axis
#29
REVIEW
Siobhain M O' Mahony, Roman M Stilling, Timothy G Dinan, John F Cryan
Many childhood diseases such as autism spectrum disorders, allergic disease, and obesity are on the increase. Although environmental factors are thought to play a role in this increase. The mechanisms at play are unclear but increasing evidence points to an interaction with the gastrointestinal microbiota as being potentially important. Recently this community of bacteria and perturbation of its colonization in early life has been linked to a number of diseases. Many factors are capable of influencing this colonization and ultimately leading to an altered gut microbiota which is known to affect key systems within the body...
December 2015: Birth Defects Research. Part C, Embryo Today: Reviews
https://read.qxmd.com/read/26702563/introduction
#30
Sharon B Meropol, Michiko Watanabe, Rocky S Tuan
No abstract text is available yet for this article.
December 2015: Birth Defects Research. Part C, Embryo Today: Reviews
https://read.qxmd.com/read/26663884/microbial-programming-of-health-and-disease-starts-during-fetal-life
#31
REVIEW
Petya T Koleva, Ji-Sun Kim, James A Scott, Anita L Kozyrskyj
The pioneer microbiota of the neonatal gut are essential for gut maturation, and metabolic and immunologic programming. Recent research has shown that early bacterial colonization may impact the occurrence of disease later in life (microbial programming). Despite early conflicting evidence, it has long been considered that the womb is a sterile environment and human microbial colonization begins at birth. In the last few years, several findings have reiterated the presence of microbes in infant first stool (meconium) and pointed to the existence of in utero microbial colonization of the infant gut...
December 2015: Birth Defects Research. Part C, Embryo Today: Reviews
https://read.qxmd.com/read/26663871/the-influence-of-the-young-microbiome-on-inflammatory-diseases-lessons-from-animal-studies
#32
REVIEW
Katja M Bendtsen, Line Fisker, Axel K Hansen, Camilla H F Hansen, Dennis S Nielsen
Chronic inflammatory diseases are on the rise in the Westernized world. This rise has been correlated to a range of environmental factors, such as birth mode, rural versus urban living conditions, and use of antibiotics. Such environmental factors also influence early life gut microbiota (GM) colonization and maturation--and there is growing evidence that the negative effects of these factors on human health are mediated via GM alterations. Colonization of the gut initiates priming of the immune system from birth, driving tolerance towards non-harmful microorganisms and dietary antigens and proper reactions towards invading pathogens...
December 2015: Birth Defects Research. Part C, Embryo Today: Reviews
https://read.qxmd.com/read/26663857/the-very-low-birth-weight-infant-microbiome-and-childhood-health
#33
REVIEW
Maureen W Groer, Katherine E Gregory, Adetola Louis-Jacques, Shelley Thibeau, W Allan Walker
This review describes current understandings about the nature of the very low birth weight infant (VLBW) gut microbiome. VLBW infants often experience disruptive pregnancies and births, and prenatal factors can influence the maturity of the gut and immune system, and disturb microbial balance and succession. Many VLBWs experience rapid vaginal or Caesarean births. After birth these infants often have delays in enteral feeding, and many receive little or no mother's own milk. Furthermore the stressors of neonatal life in the hospital environment, common use of antibiotics, invasive procedures and maternal separation can contribute to dysbiosis...
December 2015: Birth Defects Research. Part C, Embryo Today: Reviews
https://read.qxmd.com/read/26663826/development-of-the-infant-intestinal-microbiome-a-bird-s-eye-view-of-a-complex-process
#34
REVIEW
Sharon B Meropol, Amy Edwards
Infants undergo profound shifts in colonizing intestinal microorganisms during their first year, especially during and after birth and during weaning. Microbiota are passed to infants through the placenta, during the vaginal birth process, and from early diet and other environmental exposures. These microbiota play an active role in the development of healthy infant metabolic and immunologic systems; profound shifts in microbiotal populations can be persistent, are associated with immediate alterations in gene expression, metabolic, immunologic, and neurologic function, and with downstream metabolic and immunologic consequences such as obesity, allergies, asthma, autoimmune diseases, and potentially neurologic conditions...
December 2015: Birth Defects Research. Part C, Embryo Today: Reviews
https://read.qxmd.com/read/26607554/on-the-origin-of-species-factors-shaping-the-establishment-of-infant-s-gut-microbiota
#35
REVIEW
Niels van Best, Mathias W Hornef, Paul H M Savelkoul, John Penders
The human gut microbiota is a complex and dynamic ecosystem, which naturally lives in a symbiotic relationship with the host. Perturbations of the microbial composition (dysbiosis) and reduced diversity may promote disease susceptibility and recurrence. In contrast to the mature intestinal microbiota of healthy adults, which appears relatively stable over time, the infant's microbiome only establishes and matures during the first years of life. In this respect, early childhood seems to represent a crucial age-window in disease prevention, since microbial diversification and maturation of the microbiome primarily occurs during this period of life...
December 2015: Birth Defects Research. Part C, Embryo Today: Reviews
https://read.qxmd.com/read/26412573/thrombosis-during-pregnancy-risks-prevention-and-treatment-for-mother-and-fetus
#36
EDITORIAL
Evi Struble, Emmanuel Fadiran, Lisa Soule
No abstract text is available yet for this article.
September 2015: Birth Defects Research. Part C, Embryo Today: Reviews
https://read.qxmd.com/read/26406886/epidemiology-of-venous-thromboembolism-vte-associated-with-pregnancy
#37
REVIEW
Leonid A Parunov, Natalia P Soshitova, Mikhail V Ovanesov, Mikhail A Panteleev, Ilya I Serebriyskiy
This review is focused on the epidemiology of venous thromboembolism (VTE), including deep vein thrombosis (DVT) and pulmonary embolism (PE), associated with pregnancy. Superficial vein thrombosis, a less hazardous and less studied type of thrombosis in pregnant women, is beyond the scope of this review. This study discusses the VTE incidence rate in women from developed countries for both antepartum and postpartum periods and for subpopulations of women affected by additional risk factors, such as thrombophilias, circulatory diseases, preeclampsia of varying degrees of severity, and Caesarean section...
September 2015: Birth Defects Research. Part C, Embryo Today: Reviews
https://read.qxmd.com/read/26404176/nonclinical-aspects-of-venous-thrombosis-in-pregnancy
#38
REVIEW
Evi Struble, Wafa Harrouk, Albert DeFelice, Belay Tesfamariam
Pregnancy is a hypercoagulable state which carries an excess risk of maternal venous thrombosis. Endothelial injury, alterations in blood flow and activation of the coagulation pathway are proposed to contribute to the hypercoagulability. The risk for thrombosis may be accentuated by certain drugs and device implants that directly or indirectly affect the coagulation pathway. To help ensure that these interventions do not result in adverse maternal or fetal outcomes during pregnancy, gravid experimental animals can be exposed to such treatments at various stages of gestation and over a dosage range that would identify hazards and inform risk assessment...
September 2015: Birth Defects Research. Part C, Embryo Today: Reviews
https://read.qxmd.com/read/26404051/diagnosis-and-management-of-thrombosis-in-pregnancy
#39
REVIEW
Barbara A Konkle
Pregnancy-related thrombosis is a major cause of maternal mortality. Pregnancy and the puerperium are associated with a fourfold to fivefold increased risk of thrombosis when compared with the nonpregnant state. The greatest time of risk is in the postpartum period. Diagnosis of venous thromboembolism (VTE) during pregnancy can be challenging as many of the symptoms can be associated with normal pregnancy. Almost all deep venous thrombosis occurs in the left leg or iliac veins. Diagnostic procedures for pulmonary embolism carry some exposure to radiation, although risks are low when compared with risks associated with an undiagnosed maternal PE...
September 2015: Birth Defects Research. Part C, Embryo Today: Reviews
https://read.qxmd.com/read/26403978/thrombosis-during-pregnancy-risks-prevention-and-treatment-for-mother-and-fetus-harvesting-the-power-of-omic-technology-biomarkers-and-in-vitro-or-in-vivo-models-to-facilitate-the-treatment-of-thrombosis
#40
REVIEW
Sara Ornaghi, Martin Mueller, Eytan R Barnea, Michael J Paidas
Maternal thromboembolism and a spectrum of placenta-mediated complications including the pre-eclampsia syndromes, fetal growth restriction, fetal loss, and abruption manifest a shared etiopathogenesis and predisposing risk factors. Furthermore, these maternal and fetal complications are often linked to subsequent maternal health consequences that comprise the metabolic syndrome, namely, thromboembolism, chronic hypertension, and type II diabetes. Traditionally, several lines of evidence have linked vasoconstriction, excessive thrombosis and inflammation, and impaired trophoblast invasion at the uteroplacental interface as hallmark features of the placental complications...
September 2015: Birth Defects Research. Part C, Embryo Today: Reviews
journal
journal
40387
2
3
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.