Atsushi Yabuki, Ayako Muraoka, Satoko Osuka, Akira Yokoi, Kosuke Yoshida, Masami Kitagawa, Bayasura, Reina Sonehara, Natsuki Miyake, Natsuki Nakanishi, Tomoko Nakamura, Akira Iwase, Hiroaki Kajiyama
Ovarian endometrioma (OE) is a common gynecological disease that is often treated with surgery and hormonal treatment. However, ovarian cystectomy can impair the ovarian reserve (OR). Previously, we showed that perioperative administration of dienogest (DNG) is an effective option for OR preservation. However, there were differences in the extent of OR preservation among patients following perioperative DNG treatment. In the current study, we performed a global examination of serum microRNAs (miRNAs) to identify accurate biomarkers that predict post-operative restoration of OR following perioperative DNG treatment...
November 21, 2023: Reproductive Biology